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Items: 13

1.

Transcriptional regulation is insufficient to explain substrate-induced flux changes in Bacillus subtilis.

Chubukov V, Uhr M, Le Chat L, Kleijn RJ, Jules M, Link H, Aymerich S, Stelling J, Sauer U.

Mol Syst Biol. 2013 Nov 26;9:709. doi: 10.1038/msb.2013.66.

2.

The IHF regulon of exponentially growing Pseudomonas putida cells.

Silva-Rocha R, Chavarría M, Kleijn RJ, Sauer U, de Lorenzo V.

Environ Microbiol. 2013 Jan;15(1):49-63. doi: 10.1111/j.1462-2920.2012.02750.x. Epub 2012 Apr 18.

PMID:
22510163
3.

Regulatory tasks of the phosphoenolpyruvate-phosphotransferase system of Pseudomonas putida in central carbon metabolism.

Chavarría M, Kleijn RJ, Sauer U, Pflüger-Grau K, de Lorenzo V.

MBio. 2012 Mar 20;3(2). pii: e00028-12. doi: 10.1128/mBio.00028-12. Print 2012.

4.

Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism.

Buescher JM, Liebermeister W, Jules M, Uhr M, Muntel J, Botella E, Hessling B, Kleijn RJ, Le Chat L, Lecointe F, Mäder U, Nicolas P, Piersma S, Rügheimer F, Becher D, Bessieres P, Bidnenko E, Denham EL, Dervyn E, Devine KM, Doherty G, Drulhe S, Felicori L, Fogg MJ, Goelzer A, Hansen A, Harwood CR, Hecker M, Hubner S, Hultschig C, Jarmer H, Klipp E, Leduc A, Lewis P, Molina F, Noirot P, Peres S, Pigeonneau N, Pohl S, Rasmussen S, Rinn B, Schaffer M, Schnidder J, Schwikowski B, Van Dijl JM, Veiga P, Walsh S, Wilkinson AJ, Stelling J, Aymerich S, Sauer U.

Science. 2012 Mar 2;335(6072):1099-103. doi: 10.1126/science.1206871.

5.

Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli.

Haverkorn van Rijsewijk BR, Nanchen A, Nallet S, Kleijn RJ, Sauer U.

Mol Syst Biol. 2011 Mar 29;7:477. doi: 10.1038/msb.2011.9.

6.

Regulation of CodY activity through modulation of intracellular branched-chain amino acid pools.

Brinsmade SR, Kleijn RJ, Sauer U, Sonenshein AL.

J Bacteriol. 2010 Dec;192(24):6357-68. doi: 10.1128/JB.00937-10. Epub 2010 Oct 8.

7.

Metabolic fluxes during strong carbon catabolite repression by malate in Bacillus subtilis.

Kleijn RJ, Buescher JM, Le Chat L, Jules M, Aymerich S, Sauer U.

J Biol Chem. 2010 Jan 15;285(3):1587-96. doi: 10.1074/jbc.M109.061747. Epub 2009 Nov 16.

8.

Metabolic flux analysis of a glycerol-overproducing Saccharomyces cerevisiae strain based on GC-MS, LC-MS and NMR-derived C-labelling data.

Kleijn RJ, Geertman JM, Nfor BK, Ras C, Schipper D, Pronk JT, Heijnen JJ, van Maris AJ, van Winden WA.

FEMS Yeast Res. 2007 Mar;7(2):216-31. Epub 2006 Nov 21.

9.

Cytosolic NADPH metabolism in penicillin-G producing and non-producing chemostat cultures of Penicillium chrysogenum.

Kleijn RJ, Liu F, van Winden WA, van Gulik WM, Ras C, Heijnen JJ.

Metab Eng. 2007 Jan;9(1):112-23. Epub 2006 Aug 18.

PMID:
17008114
10.

13C-labeled gluconate tracing as a direct and accurate method for determining the pentose phosphate pathway split ratio in Penicillium chrysogenum.

Kleijn RJ, van Winden WA, Ras C, van Gulik WM, Schipper D, Heijnen JJ.

Appl Environ Microbiol. 2006 Jul;72(7):4743-54.

11.

Measurement of intracellular metabolites of primary metabolism and adenine nucleotides in chemostat cultivated Penicillium chrysogenum.

Nasution U, van Gulik WM, Kleijn RJ, van Winden WA, Proell A, Heijnen JJ.

Biotechnol Bioeng. 2006 May 5;94(1):159-66.

PMID:
16508996
12.
13.

Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of (13)C-labeled primary metabolites.

van Winden WA, van Dam JC, Ras C, Kleijn RJ, Vinke JL, van Gulik WM, Heijnen JJ.

FEMS Yeast Res. 2005 Apr;5(6-7):559-68.

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