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Items: 18


Oncolytic virotherapy in glioblastoma patients induces a tumor macrophage phenotypic shift leading to an altered glioblastoma microenvironment.

van den Bossche WBL, Kleijn A, Teunissen CE, Voerman JSA, Teodosio C, Noske DP, van Dongen JJM, Dirven CMF, Lamfers MLM.

Neuro Oncol. 2018 Oct 9;20(11):1494-1504. doi: 10.1093/neuonc/noy082.


Cerebrospinal fluid biomarkers of malignancies located in the central nervous system.

Verheul C, Kleijn A, Lamfers MLM.

Handb Clin Neurol. 2017;146:139-169. doi: 10.1016/B978-0-12-804279-3.00010-1. Review.


The Sequence of Delta24-RGD and TMZ Administration in Malignant Glioma Affects the Role of CD8+T Cell Anti-tumor Activity.

Kleijn A, van den Bossche W, Haefner ES, Belcaid Z, Burghoorn-Maas C, Kloezeman JJ, Pas SD, Leenstra S, Debets R, de Vrij J, Dirven CMF, Lamfers MLM.

Mol Ther Oncolytics. 2017 Mar 1;5:11-19. doi: 10.1016/j.omto.2017.02.002. eCollection 2017 Jun 16.


A Systematic Comparison Identifies an ATP-Based Viability Assay as Most Suitable Read-Out for Drug Screening in Glioma Stem-Like Cells.

Kleijn A, Kloezeman JJ, Balvers RK, van der Kaaij M, Dirven CM, Leenstra S, Lamfers ML.

Stem Cells Int. 2016;2016:5623235. doi: 10.1155/2016/5623235. Epub 2016 May 5.


The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells.

Berghauser Pont LM, Kleijn A, Kloezeman JJ, van den Bossche W, Kaufmann JK, de Vrij J, Leenstra S, Dirven CM, Lamfers ML.

PLoS One. 2015 May 18;10(5):e0127058. doi: 10.1371/journal.pone.0127058. eCollection 2015.


The therapeutic efficacy of the oncolytic virus Delta24-RGD in a murine glioma model depends primarily on antitumor immunity.

Kleijn A, Kloezeman J, Treffers-Westerlaken E, Fulci G, Leenstra S, Dirven C, Debets R, Lamfers M.

Oncoimmunology. 2014 Dec 13;3(9):e955697. eCollection 2014 Oct.


ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.

Balvers RK, Lamfers ML, Kloezeman JJ, Kleijn A, Berghauser Pont LM, Dirven CM, Leenstra S.

J Transl Med. 2015 Feb 26;13:74. doi: 10.1186/s12967-015-0427-y.


Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.

de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML.

Int J Cancer. 2015 Oct 1;137(7):1630-42. doi: 10.1002/ijc.29521. Epub 2015 Apr 7.


Establishing the Lysine-rich Protein CEST Reporter Gene as a CEST MR Imaging Detector for Oncolytic Virotherapy.

Farrar CT, Buhrman JS, Liu G, Kleijn A, Lamfers ML, McMahon MT, Gilad AA, Fulci G.

Radiology. 2015 Jun;275(3):746-54. doi: 10.1148/radiol.14140251. Epub 2015 Feb 13.


The in vivo therapeutic efficacy of the oncolytic adenovirus Delta24-RGD is mediated by tumor-specific immunity.

Kleijn A, Kloezeman J, Treffers-Westerlaken E, Fulci G, Leenstra S, Dirven C, Debets R, Lamfers M.

PLoS One. 2014 May 27;9(5):e97495. doi: 10.1371/journal.pone.0097495. eCollection 2014.


Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model.

Jiang H, Clise-Dwyer K, Ruisaard KE, Fan X, Tian W, Gumin J, Lamfers ML, Kleijn A, Lang FF, Yung WK, Vence LM, Gomez-Manzano C, Fueyo J.

PLoS One. 2014 May 14;9(5):e97407. doi: 10.1371/journal.pone.0097407. eCollection 2014.


Serum-free culture success of glial tumors is related to specific molecular profiles and expression of extracellular matrix-associated gene modules.

Balvers RK, Kleijn A, Kloezeman JJ, French PJ, Kremer A, van den Bent MJ, Dirven CM, Leenstra S, Lamfers ML.

Neuro Oncol. 2013 Dec;15(12):1684-95. doi: 10.1093/neuonc/not116. Epub 2013 Sep 17.


Employing a cylindrical single crystal in gas-surface dynamics.

Hahn C, Shan J, Liu Y, Berg O, Kleijn AW, Juurlink LB.

J Chem Phys. 2012 Mar 21;136(11):114201. doi: 10.1063/1.3692686.


Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging.

Kleijn A, Chen JW, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G.

Clin Cancer Res. 2011 Jul 1;17(13):4484-93. doi: 10.1158/1078-0432.CCR-11-0575. Epub 2011 May 10.


Health improvement through dietary management of type 2 diabetes.

De Kleijn A.

Br J Community Nurs. 2008 Aug;13(8):378, 380-3.


Oncology nursing care standards.

de Kleijn AM, Muller ME.

Curationis. 1991 Aug;14(2):23-7.


The role of the nurse in renal care.

de Kleijn AM.

Curationis. 1978 Dec;1(3):31-2. No abstract available.


Experimental Physiology of the Labyrinth.

de Kleijn A.

Proc R Soc Med. 1924;17(Otol Sect):6-27. No abstract available.

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