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Items: 1 to 50 of 320

1.

Toward methylation-based classification of central nervous system tumors.

Hegi ME, Kleihues P, Wen PY, Suvà ML.

Neuro Oncol. 2018 Apr 9;20(5):579-581. doi: 10.1093/neuonc/noy023. No abstract available.

2.

Germline MSH6 Mutation in a Patient With Two Independent Primary Glioblastomas.

Forsström LM, Sumi K, Mäkinen MJ, Oh JE, Herva R, Kleihues P, Ohgaki H, Aaltonen LA.

J Neuropathol Exp Neurol. 2017 Oct 1;76(10):848-853. doi: 10.1093/jnen/nlx066.

PMID:
28922847
3.

Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea.

Wang Q, Satomi K, Oh JE, Hutter B, Brors B, Diessl N, Liu HK, Wolf S, Wiestler O, Kleihues P, Koelsch B, Kindler-Röhrborn A, Ohgaki H.

Am J Pathol. 2016 Oct;186(10):2569-76. doi: 10.1016/j.ajpath.2016.05.024.

PMID:
27658714
4.

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW.

Acta Neuropathol. 2016 Jun;131(6):803-20. doi: 10.1007/s00401-016-1545-1. Epub 2016 May 9. Review.

PMID:
27157931
5.

Genetic Alterations in Gliosarcoma and Giant Cell Glioblastoma.

Oh JE, Ohta T, Nonoguchi N, Satomi K, Capper D, Pierscianek D, Sure U, Vital A, Paulus W, Mittelbronn M, Antonelli M, Kleihues P, Giangaspero F, Ohgaki H.

Brain Pathol. 2016 Jul;26(4):517-22. doi: 10.1111/bpa.12328. Epub 2015 Dec 16.

PMID:
26443480
6.

Alterations of the RRAS and ERCC1 genes at 19q13 in gemistocytic astrocytomas.

Ohta T, Kim YH, Oh JE, Satomi K, Nonoguchi N, Keyvani K, Pierscianek D, Sure U, Mittelbronn M, Paulus W, Vital A, Yokoo H, McDonald K, Kleihues P, Nazaret N, Barbet F, Lachuer J, Ohgaki H.

J Neuropathol Exp Neurol. 2014 Oct;73(10):908-15. doi: 10.1097/NEN.0000000000000110.

PMID:
25192052
7.

TP53, MSH4, and LATS1 germline mutations in a family with clustering of nervous system tumors.

Kim YH, Ohta T, Oh JE, Le Calvez-Kelm F, McKay J, Voegele C, Durand G, Mittelbronn M, Kleihues P, Paulus W, Ohgaki H.

Am J Pathol. 2014 Sep;184(9):2374-81. doi: 10.1016/j.ajpath.2014.05.017. Epub 2014 Jul 18.

PMID:
25041856
8.

International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading.

Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, von Deimling A, Aldape K, Brat D, Collins VP, Eberhart C, Figarella-Branger D, Fuller GN, Giangaspero F, Giannini C, Hawkins C, Kleihues P, Korshunov A, Kros JM, Beatriz Lopes M, Ng HK, Ohgaki H, Paulus W, Pietsch T, Rosenblum M, Rushing E, Soylemezoglu F, Wiestler O, Wesseling P; International Society Of Neuropathology--Haarlem.

Brain Pathol. 2014 Sep;24(5):429-35. doi: 10.1111/bpa.12171. Epub 2014 Sep 10.

PMID:
24990071
9.

Definition of primary and secondary glioblastoma--response.

Ohgaki H, Burger P, Kleihues P.

Clin Cancer Res. 2014 Apr 1;20(7):2013. doi: 10.1158/1078-0432.CCR-14-0238. Epub 2014 Feb 20. No abstract available.

10.

TERT promoter mutations in primary and secondary glioblastomas.

Nonoguchi N, Ohta T, Oh JE, Kim YH, Kleihues P, Ohgaki H.

Acta Neuropathol. 2013 Dec;126(6):931-7. doi: 10.1007/s00401-013-1163-0. Epub 2013 Aug 17.

PMID:
23955565
11.

Reply to Marc Scherer.

Kleihues P.

Brain Pathol. 2013 Jul;23(4):488. doi: 10.1111/bpa.12067. No abstract available.

PMID:
23773604
12.

Role of Biomarkers in the Clinical Management of Glioblastomas: What are the Barriers and How Can We Overcome Them?

McDonald KL, Aw G, Kleihues P.

Front Neurol. 2013 Jan 18;3:188. doi: 10.3389/fneur.2012.00188. eCollection 2012.

13.

The definition of primary and secondary glioblastoma.

Ohgaki H, Kleihues P.

Clin Cancer Res. 2013 Feb 15;19(4):764-72. doi: 10.1158/1078-0432.CCR-12-3002. Epub 2012 Dec 3. Review.

14.

Genetic profile of astrocytic and oligodendroglial gliomas.

Ohgaki H, Kleihues P.

Brain Tumor Pathol. 2011 Jul;28(3):177-83. doi: 10.1007/s10014-011-0029-1. Epub 2011 Mar 26. Review.

PMID:
21442241
15.

Molecular classification of low-grade diffuse gliomas.

Kim YH, Nobusawa S, Mittelbronn M, Paulus W, Brokinkel B, Keyvani K, Sure U, Wrede K, Nakazato Y, Tanaka Y, Vital A, Mariani L, Stawski R, Watanabe T, De Girolami U, Kleihues P, Ohgaki H.

Am J Pathol. 2010 Dec;177(6):2708-14. doi: 10.2353/ajpath.2010.100680. Epub 2010 Nov 12.

16.

Genetic profiling of CNS tumors extends histological classification.

Paulus W, Kleihues P.

Acta Neuropathol. 2010 Aug;120(2):269-70. doi: 10.1007/s00401-010-0710-1. No abstract available.

PMID:
20532895
17.

Intratumoral patterns of genomic imbalance in glioblastomas.

Nobusawa S, Lachuer J, Wierinckx A, Kim YH, Huang J, Legras C, Kleihues P, Ohgaki H.

Brain Pathol. 2010 Sep;20(5):936-44. doi: 10.1111/j.1750-3639.2010.00395.x. Epub 2010 Mar 18.

PMID:
20406234
18.

IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas.

Nobusawa S, Watanabe T, Kleihues P, Ohgaki H.

Clin Cancer Res. 2009 Oct 1;15(19):6002-7. doi: 10.1158/1078-0432.CCR-09-0715. Epub 2009 Sep 15.

19.

Genetic alterations and signaling pathways in the evolution of gliomas.

Ohgaki H, Kleihues P.

Cancer Sci. 2009 Dec;100(12):2235-41. doi: 10.1111/j.1349-7006.2009.01308.x. Epub 2009 Aug 6. Review.

20.

Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li-Fraumeni syndrome.

Watanabe T, Vital A, Nobusawa S, Kleihues P, Ohgaki H.

Acta Neuropathol. 2009 Jun;117(6):653-6. doi: 10.1007/s00401-009-0528-x. Epub 2009 Apr 2.

PMID:
19340432
21.

Age as a predictive factor in glioblastomas: population-based study.

Kita D, Ciernik IF, Vaccarella S, Franceschi S, Kleihues P, Lütolf UM, Ohgaki H.

Neuroepidemiology. 2009;33(1):17-22. doi: 10.1159/000210017. Epub 2009 Mar 27.

22.

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas.

Watanabe T, Nobusawa S, Kleihues P, Ohgaki H.

Am J Pathol. 2009 Apr;174(4):1149-53. doi: 10.2353/ajpath.2009.080958. Epub 2009 Feb 26.

23.

The 2007 WHO classification of tumours of the central nervous system.

Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P.

Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 2007 Nov;114(5):547.

24.

Genetic pathways to primary and secondary glioblastoma.

Ohgaki H, Kleihues P.

Am J Pathol. 2007 May;170(5):1445-53. Review.

25.

Brain tumors in S100beta-v-erbB transgenic rats.

Ohgaki H, Kita D, Favereaux A, Huang H, Homma T, Dessen P, Weiss WA, Kleihues P, Heppner FL.

J Neuropathol Exp Neurol. 2006 Dec;65(12):1111-7.

PMID:
17146284
26.

Stratification of medulloblastoma on the basis of histopathological grading.

Giangaspero F, Wellek S, Masuoka J, Gessi M, Kleihues P, Ohgaki H.

Acta Neuropathol. 2006 Jul;112(1):5-12. Epub 2006 Apr 29.

PMID:
16685513
27.

Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas.

Ohgaki H, Kleihues P.

J Neuropathol Exp Neurol. 2005 Jun;64(6):479-89. Review.

PMID:
15977639
28.

Epidemiology and etiology of gliomas.

Ohgaki H, Kleihues P.

Acta Neuropathol. 2005 Jan;109(1):93-108. Epub 2005 Feb 1. Review.

PMID:
15685439
29.

Molecular pathogenesis of astrocytic tumours.

Ichimura K, Ohgaki H, Kleihues P, Collins VP.

J Neurooncol. 2004 Nov;70(2):137-60. Review.

PMID:
15674475
30.

Genetic pathways to glioblastoma: a population-based study.

Ohgaki H, Dessen P, Jourde B, Horstmann S, Nishikawa T, Di Patre PL, Burkhard C, Schüler D, Probst-Hensch NM, Maiorka PC, Baeza N, Pisani P, Yonekawa Y, Yasargil MG, Lütolf UM, Kleihues P.

Cancer Res. 2004 Oct 1;64(19):6892-9.

31.

Genetic and expression profiles of cerebellar liponeurocytomas.

Horstmann S, Perry A, Reifenberger G, Giangaspero F, Huang H, Hara A, Masuoka J, Rainov NG, Bergmann M, Heppner FL, Brandner S, Chimelli L, Montagna N, Jackson T, Davis DG, Markesbery WR, Ellison DW, Weller RO, Taddei GL, Conti R, Del Bigio MR, González-Cámpora R, Radhakrishnan VV, Söylemezoglu F, Uro-Coste E, Qian J, Kleihues P, Ohgaki H.

Brain Pathol. 2004 Jul;14(3):281-9.

PMID:
15446583
32.

The science and practice of carcinogen identification and evaluation.

Cogliano VJ, Baan RA, Straif K, Grosse Y, Secretan MB, El Ghissassi F, Kleihues P.

Environ Health Perspect. 2004 Sep;112(13):1269-74. Review.

33.

Gene expression profiling and subgroup identification of oligodendrogliomas.

Huang H, Okamoto Y, Yokoo H, Heppner FL, Vital A, Fevre-Montange M, Jouvet A, Yonekawa Y, Lazaridis EN, Kleihues P, Ohgaki H.

Oncogene. 2004 Aug 5;23(35):6012-22.

PMID:
15208679
34.

Predominant expression of mutant EGFR (EGFRvIII) is rare in primary glioblastomas.

Biernat W, Huang H, Yokoo H, Kleihues P, Ohgaki H.

Brain Pathol. 2004 Apr;14(2):131-6.

PMID:
15193025
35.

Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas.

Okamoto Y, Di Patre PL, Burkhard C, Horstmann S, Jourde B, Fahey M, Schüler D, Probst-Hensch NM, Yasargil MG, Yonekawa Y, Lütolf UM, Kleihues P, Ohgaki H.

Acta Neuropathol. 2004 Jul;108(1):49-56. Epub 2004 Apr 28.

PMID:
15118874
36.

Endogenous deoxyribonucleic Acid (DNA) damage in human tissues: a comparison of ethenobases with aldehydic DNA lesions.

Barbin A, Ohgaki H, Nakamura J, Kurrer M, Kleihues P, Swenberg JA.

Cancer Epidemiol Biomarkers Prev. 2003 Nov;12(11 Pt 1):1241-7.

37.

Cerebellar liponeurocytoma with an unusually aggressive clinical course: case report.

Jenkinson MD, Bosma JJ, Du Plessis D, Ohgaki H, Kleihues P, Warnke P, Rainov NG.

Neurosurgery. 2003 Dec;53(6):1425-7; discussion 1428.

PMID:
14633310
38.

Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype.

Olivier M, Goldgar DE, Sodha N, Ohgaki H, Kleihues P, Hainaut P, Eeles RA.

Cancer Res. 2003 Oct 15;63(20):6643-50.

39.

PTEN methylation and expression in glioblastomas.

Baeza N, Weller M, Yonekawa Y, Kleihues P, Ohgaki H.

Acta Neuropathol. 2003 Nov;106(5):479-85. Epub 2003 Aug 2.

PMID:
12904991
40.

A population-based study of the incidence and survival rates in patients with pilocytic astrocytoma.

Burkhard C, Di Patre PL, Schüler D, Schüler G, Yaşargil MG, Yonekawa Y, Lütolf UM, Kleihues P, Ohgaki H.

J Neurosurg. 2003 Jun;98(6):1170-4.

PMID:
12816259
41.

Reply to Dr. Sass.

Kleihues P, Rice J.

Int J Occup Environ Health. 2003 Jan-Mar;9(1):80-1. No abstract available.

PMID:
12749636
42.

Integrity of the conduct of the IARC monographs program.

Kleihues P.

Int J Occup Environ Health. 2003 Jan-Mar;9(1):78-9; author reply 82. No abstract available.

PMID:
12749635
43.

Transparency at the International Agency for Research on Cancer (IARC).

Kleihues P; International Agency for Research on Cancer.

Lancet. 2003 Mar 1;361(9359):781. No abstract available.

PMID:
12620755
44.

AXIN1 mutations but not deletions in cerebellar medulloblastomas.

Baeza N, Masuoka J, Kleihues P, Ohgaki H.

Oncogene. 2003 Jan 30;22(4):632-6.

PMID:
12555076
45.

Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice.

Tong WM, Ohgaki H, Huang H, Granier C, Kleihues P, Wang ZQ.

Am J Pathol. 2003 Jan;162(1):343-52.

46.

Nutrition and cancer: a complex relationship.

Riboli E, Lambert R, Kleihues P.

IARC Sci Publ. 2002;156:3-4. No abstract available.

PMID:
12484109
47.

Methylation of the p73 gene in gliomas.

Watanabe T, Huang H, Nakamura M, Wischhusen J, Weller M, Kleihues P, Ohgaki H.

Acta Neuropathol. 2002 Oct;104(4):357-62. Epub 2002 Jul 3.

PMID:
12200621
48.

Prognostic impact of TP53 mutations and P53 protein overexpression in supratentorial WHO grade II astrocytomas and oligoastrocytomas.

Peraud A, Kreth FW, Wiestler OD, Kleihues P, Reulen HJ.

Clin Cancer Res. 2002 May;8(5):1117-24.

49.

Phenotype versus genotype correlation in oligodendrogliomas and low-grade diffuse astrocytomas.

Watanabe T, Nakamura M, Kros JM, Burkhard C, Yonekawa Y, Kleihues P, Ohgaki H.

Acta Neuropathol. 2002 Mar;103(3):267-75. Epub 2001 Nov 22.

PMID:
11907807
50.

The WHO classification of tumors of the nervous system.

Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, Cavenee WK.

J Neuropathol Exp Neurol. 2002 Mar;61(3):215-25; discussion 226-9. Review.

PMID:
11895036

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