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Pulsed Electrical Stimulation of the Human Eye Enhances Retinal Vessel Reaction to Flickering Light.

Freitag S, Hunold A, Klemm M, Klee S, Link D, Nagel E, Haueisen J.

Front Hum Neurosci. 2019 Oct 22;13:371. doi: 10.3389/fnhum.2019.00371. eCollection 2019.


Erwinia amylovora Auxotrophic Mutant Exometabolomics and Virulence on Apples.

Klee SM, Sinn JP, Finley M, Allman EL, Smith PB, Aimufua O, Sitther V, Lehman BL, Krawczyk T, Peter KA, McNellis TW.

Appl Environ Microbiol. 2019 Jul 18;85(15). pii: e00935-19. doi: 10.1128/AEM.00935-19. Print 2019 Aug 1.


The Apple Fruitlet Model System for Fire Blight Disease.

Klee SM, Sinn JP, McNellis TW.

Methods Mol Biol. 2019;1991:187-198. doi: 10.1007/978-1-4939-9458-8_17.


Objective measurement of forward-scattered light in the human eye: An electrophysiological approach.

Solf B, Schramm S, Link D, Klee S.

PLoS One. 2019 Apr 4;14(4):e0214850. doi: 10.1371/journal.pone.0214850. eCollection 2019.


Bleaching effects and fluorescence lifetime imaging ophthalmoscopy.

Klemm M, Sauer L, Klee S, Link D, Peters S, Hammer M, Schweitzer D, Haueisen J.

Biomed Opt Express. 2019 Feb 28;10(3):1446-1461. doi: 10.1364/BOE.10.001446. eCollection 2019 Mar 1.


Extragenic Suppression of Elongation Factor P Gene Mutant Phenotypes in Erwinia amylovora.

Klee SM, Sinn JP, Holmes AC, Lehman BL, Krawczyk T, Peter KA, McNellis TW.

J Bacteriol. 2019 May 8;201(11). pii: e00722-18. doi: 10.1128/JB.00722-18. Print 2019 Jun 1.


Scotoma Simulation in Healthy Subjects.

Klee S, Link D, Sinzinger S, Haueisen J.

Optom Vis Sci. 2018 Dec;95(12):1120-1128. doi: 10.1097/OPX.0000000000001310.


Analysis of a newly discovered antigen of Bacillus cereus biovar anthracis for its suitability in specific serological antibody testing.

Dupke S, Barduhn A, Franz T, Leendertz FH, Couacy-Hymann E, Grunow R, Klee SR.

J Appl Microbiol. 2019 Jan;126(1):311-323. doi: 10.1111/jam.14114. Epub 2018 Oct 29.


Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.

Lehmann M, Buhl L, Alsafadi HN, Klee S, Hermann S, Mutze K, Ota C, Lindner M, Behr J, Hilgendorff A, Wagner DE, Königshoff M.

Respir Res. 2018 Sep 15;19(1):175. doi: 10.1186/s12931-018-0876-y.


Experimental Characterization and Correlation of Mayer Waves in Retinal Vessel Diameter and Arterial Blood Pressure.

Rieger S, Klee S, Baumgarten D.

Front Physiol. 2018 Jul 13;9:892. doi: 10.3389/fphys.2018.00892. eCollection 2018.


S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis.

Zhang W, Ohno S, Steer B, Klee S, Staab-Weijnitz CA, Wagner D, Lehmann M, Stoeger T, Königshoff M, Adler H.

Front Immunol. 2018 Jun 1;9:1216. doi: 10.3389/fimmu.2018.01216. eCollection 2018.


An Erwinia amylovora yjeK mutant exhibits reduced virulence, increased chemical sensitivity and numerous environmentally dependent proteomic alterations.

Klee SM, Mostafa I, Chen S, Dufresne C, Lehman BL, Sinn JP, Peter KA, McNellis TW.

Mol Plant Pathol. 2018 Jul;19(7):1667-1678. doi: 10.1111/mpp.12650. Epub 2018 Feb 1.


Low antibody prevalence against Bacillus cereus biovar anthracis in Taï National Park, Côte d'Ivoire, indicates high rate of lethal infections in wildlife.

Zimmermann F, Köhler SM, Nowak K, Dupke S, Barduhn A, Düx A, Lang A, De Nys HM, Gogarten JF, Grunow R, Couacy-Hymann E, Wittig RM, Klee SR, Leendertz FH.

PLoS Negl Trop Dis. 2017 Sep 21;11(9):e0005960. doi: 10.1371/journal.pntd.0005960. eCollection 2017 Sep.


Structural and immunochemical relatedness suggests a conserved pathogenicity motif for secondary cell wall polysaccharides in Bacillus anthracis and infection-associated Bacillus cereus.

Kamal N, Ganguly J, Saile E, Klee SR, Hoffmaster A, Carlson RW, Forsberg LS, Kannenberg EL, Quinn CP.

PLoS One. 2017 Aug 23;12(8):e0183115. doi: 10.1371/journal.pone.0183115. eCollection 2017.


Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.

Lehmann M, Korfei M, Mutze K, Klee S, Skronska-Wasek W, Alsafadi HN, Ota C, Costa R, Schiller HB, Lindner M, Wagner DE, Günther A, Königshoff M.

Eur Respir J. 2017 Aug 3;50(2). pii: 1602367. doi: 10.1183/13993003.02367-2016. Print 2017 Aug.


Persistent anthrax as a major driver of wildlife mortality in a tropical rainforest.

Hoffmann C, Zimmermann F, Biek R, Kuehl H, Nowak K, Mundry R, Agbor A, Angedakin S, Arandjelovic M, Blankenburg A, Brazolla G, Corogenes K, Couacy-Hymann E, Deschner T, Dieguez P, Dierks K, Düx A, Dupke S, Eshuis H, Formenty P, Yuh YG, Goedmakers A, Gogarten JF, Granjon AC, McGraw S, Grunow R, Hart J, Jones S, Junker J, Kiang J, Langergraber K, Lapuente J, Lee K, Leendertz SA, Léguillon F, Leinert V, Löhrich T, Marrocoli S, Mätz-Rensing K, Meier A, Merkel K, Metzger S, Murai M, Niedorf S, De Nys H, Sachse A, van Schijndel J, Thiesen U, Ton E, Wu D, Wieler LH, Boesch C, Klee SR, Wittig RM, Calvignac-Spencer S, Leendertz FH.

Nature. 2017 Aug 2;548(7665):82-86. doi: 10.1038/nature23309.


Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis.

Hofmann K, Fiedler S, Vierkotten S, Weber J, Klee S, Jia J, Zwickenpflug W, Flockerzi V, Storch U, Yildirim AÖ, Gudermann T, Königshoff M, Dietrich A.

Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):560-568. doi: 10.1016/j.bbadis.2016.12.002. Epub 2016 Dec 6.


Bacillus cereus Biovar Anthracis Causing Anthrax in Sub-Saharan Africa-Chromosomal Monophyly and Broad Geographic Distribution.

Antonation KS, Grützmacher K, Dupke S, Mabon P, Zimmermann F, Lankester F, Peller T, Feistner A, Todd A, Herbinger I, de Nys HM, Muyembe-Tamfun JJ, Karhemere S, Wittig RM, Couacy-Hymann E, Grunow R, Calvignac-Spencer S, Corbett CR, Klee SR, Leendertz FH.

PLoS Negl Trop Dis. 2016 Sep 8;10(9):e0004923. doi: 10.1371/journal.pntd.0004923. eCollection 2016 Sep.


Rod Driven Frequency Entrainment and Resonance Phenomena.

Salchow C, Strohmeier D, Klee S, Jannek D, Schiecke K, Witte H, Nehorai A, Haueisen J.

Front Hum Neurosci. 2016 Aug 18;10:413. doi: 10.3389/fnhum.2016.00413. eCollection 2016.


Brucellosis in a refugee who migrated from Syria to Germany and lessons learnt, 2016.

Grunow R, Jacob D, Klee S, Schlembach D, Jackowski-Dohrmann S, Loenning-Baucke V, Eberspächer B, Swidsinski S.

Euro Surveill. 2016 Aug 4;21(31). doi: 10.2807/1560-7917.ES.2016.21.31.30311.


Source localization of S-cone and L/M-cone driven signals using silent substitution flash stimulation.

Klee S, Liebermann J, Haueisen J.

Biomed Tech (Berl). 2017 May 24;62(3):339-348. doi: 10.1515/bmt-2015-0240.


Whole Genome Analysis of Injectional Anthrax Identifies Two Disease Clusters Spanning More Than 13 Years.

Keim P, Grunow R, Vipond R, Grass G, Hoffmaster A, Birdsell DN, Klee SR, Pullan S, Antwerpen M, Bayer BN, Latham J, Wiggins K, Hepp C, Pearson T, Brooks T, Sahl J, Wagner DM.

EBioMedicine. 2015 Oct 6;2(11):1613-8. doi: 10.1016/j.ebiom.2015.10.004. eCollection 2015 Nov.


WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts.

Klee S, Lehmann M, Wagner DE, Baarsma HA, Königshoff M.

Sci Rep. 2016 Feb 12;6:20547. doi: 10.1038/srep20547.


Xenophilus feline species goes human.-Watch out for neglected zoonotic pathogens when treating animal bites.

Haditsch M, Klee SR.

Travel Med Infect Dis. 2015 Nov-Dec;13(6):503-4. doi: 10.1016/j.tmaid.2015.11.004. Epub 2015 Nov 19. No abstract available.


Capsules, toxins and AtxA as virulence factors of emerging Bacillus cereus biovar anthracis.

Brézillon C, Haustant M, Dupke S, Corre JP, Lander A, Franz T, Monot M, Couture-Tosi E, Jouvion G, Leendertz FH, Grunow R, Mock ME, Klee SR, Goossens PL.

PLoS Negl Trop Dis. 2015 Apr 1;9(4):e0003455. doi: 10.1371/journal.pntd.0003455. eCollection 2015 Apr. Erratum in: PLoS Negl Trop Dis. 2015 Apr;9(4):e0003746.


Development of an ion activation stage for atmospheric pressure ionization sources.

Klee S, Brockhaus A, Wißdorf W, Thinius M, Hartmann N, Benter T.

Rapid Commun Mass Spectrom. 2015 Jan 30;29(2):143-54. doi: 10.1002/rcm.7082.


Capillary atmospheric pressure chemical ionization using liquid point electrodes.

Klee S, Thinius M, Brockmann KJ, Benter T.

Rapid Commun Mass Spectrom. 2014 Jul 30;28(14):1591-600. doi: 10.1002/rcm.6944.


Are clusters important in understanding the mechanisms in atmospheric pressure ionization? Part 1: Reagent ion generation and chemical control of ion populations.

Klee S, Derpmann V, Wißdorf W, Klopotowski S, Kersten H, Brockmann KJ, Benter T, Albrecht S, Bruins AP, Dousty F, Kauppila TJ, Kostiainen R, O'Brien R, Robb DB, Syage JA.

J Am Soc Mass Spectrom. 2014 Aug;25(8):1310-21. doi: 10.1007/s13361-014-0891-2. Epub 2014 May 22. Review.


Analysis of the microwave, terahertz, and far infrared spectra of monodeuterated methanol CH2DOH up to J = 26, K = 11, and o(1).

Coudert LH, Zemouli M, Motiyenko RA, Margulès L, Klee S.

J Chem Phys. 2014 Feb 14;140(6):064307. doi: 10.1063/1.4864203.


Studies of the mechanism of the cluster formation in a thermally sampling atmospheric pressure ionization mass spectrometer.

Albrecht S, Klopotowski S, Derpmann V, Klee S, Brockmann KJ, Stroh F, Benter T.

Rev Sci Instrum. 2014 Jan;85(1):014102. doi: 10.1063/1.4854855.


Identification and validation of specific markers of Bacillus anthracis spores by proteomics and genomics approaches.

Chenau J, Fenaille F, Caro V, Haustant M, Diancourt L, Klee SR, Junot C, Ezan E, Goossens PL, Becher F.

Mol Cell Proteomics. 2014 Mar;13(3):716-32. doi: 10.1074/mcp.M113.032946. Epub 2013 Dec 29.


Generation of ion-bound solvent clusters as reactant ions in dopant-assisted APPI and APLI.

Klee S, Albrecht S, Derpmann V, Kersten H, Benter T.

Anal Bioanal Chem. 2013 Sep;405(22):6933-51. doi: 10.1007/s00216-013-7114-8. Epub 2013 Jul 5.


Anthrax among heroin users in Europe possibly caused by same Bacillus anthracis strain since 2000.

Grunow R, Klee SR, Beyer W, George M, Grunow D, Barduhn A, Klar S, Jacob D, Elschner M, Sandven P, Kjerulf A, Jensen JS, Cai W, Zimmermann R, Schaade L.

Euro Surveill. 2013 Mar 28;18(13). pii: 20437.


Monte Carlo simulation of ion trajectories of reacting chemical systems: mobility of small water clusters in ion mobility spectrometry.

Wissdorf W, Seifert L, Derpmann V, Klee S, Vautz W, Benter T.

J Am Soc Mass Spectrom. 2013 Apr;24(4):632-41. doi: 10.1007/s13361-012-0553-1. Epub 2013 Mar 2.


Simulation of ion motion at atmospheric pressure: particle tracing versus electrokinetic flow.

Wissdorf W, Pohler L, Klee S, Müller D, Benter T.

J Am Soc Mass Spectrom. 2012 Feb;23(2):397-406. doi: 10.1007/s13361-011-0290-x. Epub 2011 Dec 1.


Analysis of the torsional spectrum of monodeuterated methanol CH2DOH.

El Hilali A, Coudert LH, Konov I, Klee S.

J Chem Phys. 2011 Nov 21;135(19):194309. doi: 10.1063/1.3662468.


Optoelectrophysiological stimulation of the human eye using fundus-controlled silent substitution technique.

Klee S, Link D, Bessler P, Haueisen J.

J Biomed Opt. 2011 Jan-Feb;16(1):015002. doi: 10.1117/1.3528616.


The genome of a Bacillus isolate causing anthrax in chimpanzees combines chromosomal properties of B. cereus with B. anthracis virulence plasmids.

Klee SR, Brzuszkiewicz EB, Nattermann H, Brüggemann H, Dupke S, Wollherr A, Franz T, Pauli G, Appel B, Liebl W, Couacy-Hymann E, Boesch C, Meyer FD, Leendertz FH, Ellerbrok H, Gottschalk G, Grunow R, Liesegang H.

PLoS One. 2010 Jul 9;5(7):e10986. doi: 10.1371/journal.pone.0010986.


[Investigation of a family cluster of influenza A/H1N1 infections in Germany, 2009].

Faber M, Christiansen H, Kohlstock C, Oppermann H, Irmscher HM, Willer H, Schweiger B, Dupke S, Klee S, Grunow R, Haas W, Buchholz U, Süss T, Krause G, Jansen A; Influenza A/H1N1-Untersuchungsteam des Robert Koch-Instituts.

Gesundheitswesen. 2009 Oct;71(10):675-9. doi: 10.1055/s-0029-1239565. Epub 2009 Nov 2. German.


Synthesis of a novel C2/C2'-aryl-substituted pyrrolo[2,1-c][1,4]benzodiazepine dimer prodrug with improved water solubility and reduced DNA reaction rate.

Howard PW, Chen Z, Gregson SJ, Masterson LA, Tiberghien AC, Cooper N, Fang M, Coffils MJ, Klee S, Hartley JA, Thurston DE.

Bioorg Med Chem Lett. 2009 Nov 15;19(22):6463-6. doi: 10.1016/j.bmcl.2009.09.012. Epub 2009 Sep 9.


Development of antibodies against anthrose tetrasaccharide for specific detection of Bacillus anthracis spores.

Kuehn A, Kovác P, Saksena R, Bannert N, Klee SR, Ranisch H, Grunow R.

Clin Vaccine Immunol. 2009 Dec;16(12):1728-37. doi: 10.1128/CVI.00235-09. Epub 2009 Sep 30.


Silent substitution stimulation of S-cone pathway and L- and M-cone pathway in glaucoma.

Bessler P, Klee S, Kellner U, Haueisen J.

Invest Ophthalmol Vis Sci. 2010 Jan;51(1):319-26. doi: 10.1167/iovs.09-3467. Epub 2009 Aug 26.


A 17-year-old girl with a black eschar. Cowpox virus infection.

Strenger V, Müller M, Richter S, Revilla-Fernandez S, Nitsche A, Klee SR, Ellerbrok H, Zenz W.

Clin Infect Dis. 2009 Jan 1;48(1):91-2, 133-4. doi: 10.1086/595004. No abstract available.


Occurrence and genetic diversity of Bacillus anthracis strains isolated in an active wool-cleaning factory.

Wattiau P, Klee SR, Fretin D, Van Hessche M, Ménart M, Franz T, Chasseur C, Butaye P, Imberechts H.

Appl Environ Microbiol. 2008 Jul;74(13):4005-11. doi: 10.1128/AEM.00417-08. Epub 2008 May 16.


Evaluation of a real-time PCR assay to detect Coxiella burnetii.

Klee SR, Ellerbrok H, Tyczka J, Franz T, Appel B.

Ann N Y Acad Sci. 2006 Oct;1078:563-5.


Characterization of Bacillus anthracis-like bacteria isolated from wild great apes from Cote d'Ivoire and Cameroon.

Klee SR, Ozel M, Appel B, Boesch C, Ellerbrok H, Jacob D, Holland G, Leendertz FH, Pauli G, Grunow R, Nattermann H.

J Bacteriol. 2006 Aug;188(15):5333-44.


Evaluation of different methods to discriminate Bacillus anthracis from other bacteria of the Bacillus cereus group.

Klee SR, Nattermann H, Becker S, Urban-Schriefer M, Franz T, Jacob D, Appel B.

J Appl Microbiol. 2006 Apr;100(4):673-81.


Highly sensitive real-time PCR for specific detection and quantification of Coxiella burnetii.

Klee SR, Tyczka J, Ellerbrok H, Franz T, Linke S, Baljer G, Appel B.

BMC Microbiol. 2006 Jan 19;6:2.


[Efficient killing of anthrax spores using aqueous and alcoholic peracetic acid solutions].

Nattermann H, Becker S, Jacob D, Klee SR, Schwebke I, Appel B.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2005 Aug;48(8):939-50. German.


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