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Items: 1 to 50 of 143

1.

Temsirolimus metabolic pathways revisited.

Shokati T, Hartmann M, Davari B, Klawitter J, Klawitter J, Christians U.

Xenobiotica. 2019 Oct 23:1-14. doi: 10.1080/00498254.2019.1678793. [Epub ahead of print]

PMID:
31596164
2.

Brief Report: Markers of Spontaneous Preterm Delivery in Women Living With HIV: Relationship With Protease Inhibitors and Vitamin D.

Weinberg A, Huo Y, Kacanek D, Patel K, Watts DH, Wara D, Hoffman RM, Klawitter J, Christians U; for IMPAACT P1025 Team.

J Acquir Immune Defic Syndr. 2019 Oct 1;82(2):181-187. doi: 10.1097/QAI.0000000000002111.

PMID:
31513074
3.

Cyclophilin D knockout protects the mouse kidney against cyclosporin A-induced oxidative stress.

Klawitter J, Klawitter J, Pennington A, Kirkpatrick B, Roda G, Kotecha NC, Thurman JM, Christians U.

Am J Physiol Renal Physiol. 2019 Sep 1;317(3):F683-F694. doi: 10.1152/ajprenal.00417.2018. Epub 2019 Jun 12.

PMID:
31188033
4.

Disposition of oral delta-9 tetrahydrocannabinol (THC) in children receiving cannabis extracts for epilepsy.

Wang GS, Bourne DWA, Klawitter J, Sempio C, Chapman K, Knupp K, Wempe MF, Borgelt L, Christians U, Heard K, Bajaj L.

Clin Toxicol (Phila). 2019 May 21:1-5. doi: 10.1080/15563650.2019.1616093. [Epub ahead of print]

PMID:
31111749
5.

Depressed prostaglandins and leukotrienes in veterans with Gulf War illness.

Golomb BA, Koslik HJ, Christians U, Ritchie J, Wilson P, Elkins N, Klawitter J, Klawitter J, Smith D, Repine JE.

J Environ Sci Health B. 2019;54(8):623-639. doi: 10.1080/03601234.2019.1596001. Epub 2019 Apr 29.

PMID:
31033394
6.

Elevated plasma homocysteine and cysteine are associated with endothelial dysfunction across menopausal stages in healthy women.

Keller AC, Klawitter J, Hildreth KL, Christians U, Putnam K, Kohrt WM, Reusch JEB, Moreau KL.

J Appl Physiol (1985). 2019 Jun 1;126(6):1533-1540. doi: 10.1152/japplphysiol.00819.2018. Epub 2019 Mar 21.

PMID:
30896357
7.

Mineralocorticoid Antagonism and Vascular Function in Early Autosomal Dominant Polycystic Kidney Disease: A Randomized Controlled Trial.

Nowak KL, Gitomer B, Farmer-Bailey H, Wang W, Malaczewski M, Klawitter J, You Z, George D, Patel N, Jovanovich A, Chonchol M.

Am J Kidney Dis. 2019 Aug;74(2):213-223. doi: 10.1053/j.ajkd.2018.12.037. Epub 2019 Feb 23.

PMID:
30803706
8.

Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia.

Timic Stamenic T, Feseha S, Valdez R, Zhao W, Klawitter J, Todorovic SM.

Cereb Cortex. 2019 Jan 31. doi: 10.1093/cercor/bhz002. [Epub ahead of print]

PMID:
30715245
9.

Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay.

Davidson JA, Pfeifer Z, Frank B, Tong S, Urban TT, Wischmeyer PA, Mourani P, Landeck B, Christians U, Klawitter J.

J Am Heart Assoc. 2018 Dec 18;7(24):e010711. doi: 10.1161/JAHA.118.010711.

10.

Assessment of tacrolimus intrapatient variability in stable adherent transplant recipients: Establishing baseline values.

Leino AD, King EC, Jiang W, Vinks AA, Klawitter J, Christians U, Woodle ES, Alloway RR, Rohan JM.

Am J Transplant. 2019 May;19(5):1410-1420. doi: 10.1111/ajt.15199. Epub 2018 Dec 26.

PMID:
30506623
11.

Single dose of 17β-estradiol provides transient neuroprotection in female juvenile mice after cardiac-arrest and cardiopulmonary resuscitation.

Quillinan N, Dingman AL, Deng G, Tatum S, Orfila JE, Clevenger AC, Klawitter J, Traystman RJ, Herson PS.

Neurochem Int. 2019 Jul;127:80-86. doi: 10.1016/j.neuint.2018.11.013. Epub 2018 Nov 22.

PMID:
30471325
12.

A proteomics-metabolomics approach indicates changes in hypothalamic glutamate-GABA metabolism of adult female rats submitted to intrauterine growth restriction.

Pedroso AP, Dornellas APS, de Souza AP, Pagotto JF, Oyama LM, Nascimento CMO, Klawitter J, Christians U, Tashima AK, Ribeiro EB.

Eur J Nutr. 2019 Dec;58(8):3059-3068. doi: 10.1007/s00394-018-1851-6. Epub 2018 Nov 7.

PMID:
30406389
13.

Vascular Dysfunction, Oxidative Stress, and Inflammation in Autosomal Dominant Polycystic Kidney Disease.

Nowak KL, Wang W, Farmer-Bailey H, Gitomer B, Malaczewski M, Klawitter J, Jovanovich A, Chonchol M.

Clin J Am Soc Nephrol. 2018 Oct 8;13(10):1493-1501. doi: 10.2215/CJN.05850518. Epub 2018 Sep 18.

14.

Endothelial Microparticles and Systemic Complement Activation in Patients With Chronic Kidney Disease.

Jalal D, Renner B, Laskowski J, Stites E, Cooper J, Valente K, You Z, Perrenoud L, Le Quintrec M, Muhamed I, Christians U, Klawitter J, Lindorfer MA, Taylor RP, Holers VM, Thurman JM.

J Am Heart Assoc. 2018 Jul 13;7(14). pii: e007818. doi: 10.1161/JAHA.117.007818.

15.

Treating Obstructive Sleep Apnea and Chronic Intermittent Hypoxia Improves the Severity of Nonalcoholic Fatty Liver Disease in Children.

Sundaram SS, Halbower AC, Klawitter J, Pan Z, Robbins K, Capocelli KE, Sokol RJ.

J Pediatr. 2018 Jul;198:67-75.e1. doi: 10.1016/j.jpeds.2018.03.028. Epub 2018 May 8.

PMID:
29752170
16.

A neurosteroid analogue with T-type calcium channel blocking properties is an effective hypnotic, but is not harmful to neonatal rat brain.

Atluri N, Joksimovic SM, Oklopcic A, Milanovic D, Klawitter J, Eggan P, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V.

Br J Anaesth. 2018 Apr;120(4):768-778. doi: 10.1016/j.bja.2017.12.039. Epub 2018 Feb 9.

17.

Complement factor H protects mice from ischemic acute kidney injury but is not critical for controlling complement activation by glomerular IgM.

Goetz L, Laskowski J, Renner B, Pickering MC, Kulik L, Klawitter J, Stites E, Christians U, van der Vlag J, Ravichandran K, Holers VM, Thurman JM.

Eur J Immunol. 2018 May;48(5):791-802. doi: 10.1002/eji.201747240. Epub 2018 Feb 22.

18.

Infant cardiopulmonary bypass: CD73 kinetics, association with clinical outcomes, and influence on serum adenosine production capacity.

Persson JN, Baird CH, Tong S, Urban TT, Klawitter J, Wischmeyer PE, Davidson JA.

Pediatr Res. 2018 Apr;83(4):858-865. doi: 10.1038/pr.2017.325. Epub 2018 Jan 17.

19.

Bone marrow-derived cPLA2α contributes to renal fibrosis progression.

Montford JR, Lehman AMB, Bauer CD, Klawitter J, Klawitter J, Poczobutt JM, Scobey M, Weiser-Evans M, Nemenoff RA, Furgeson SB.

J Lipid Res. 2018 Feb;59(2):380-390. doi: 10.1194/jlr.M082362. Epub 2017 Dec 11.

20.

Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial.

Alloway RR, Vinks AA, Fukuda T, Mizuno T, King EC, Zou Y, Jiang W, Woodle ES, Tremblay S, Klawitter J, Klawitter J, Christians U.

PLoS Med. 2017 Nov 14;14(11):e1002428. doi: 10.1371/journal.pmed.1002428. eCollection 2017 Nov.

21.

A relative L-arginine deficiency contributes to endothelial dysfunction across the stages of the menopausal transition.

Klawitter J, Hildreth KL, Christians U, Kohrt WM, Moreau KL.

Physiol Rep. 2017 Sep;5(17). pii: e13409. doi: 10.14814/phy2.13409.

22.

Mitochondrial cyclophilin D ablation is associated with the activation of Akt/p70S6K pathway in the mouse kidney.

Klawitter J, Pennington A, Klawitter J, Thurman JM, Christians U.

Sci Rep. 2017 Sep 5;7(1):10540. doi: 10.1038/s41598-017-10076-9.

23.

Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia.

Schroeder T, Piantadosi CA, Natoli MJ, Autmizguine J, Cohen-Wolkowieczs M, Hamilton KL, Bell C, Klawitter J, Christians U, Irwin DC, Noveck RJ.

Clin Pharmacol Ther. 2018 May;103(5):888-898. doi: 10.1002/cpt.860. Epub 2017 Oct 17.

24.

An Atmospheric Pressure Chemical Ionization MS/MS Assay Using Online Extraction for the Analysis of 11 Cannabinoids and Metabolites in Human Plasma and Urine.

Klawitter J, Sempio C, Mörlein S, De Bloois E, Klepacki J, Henthorn T, Leehey MA, Hoffenberg EJ, Knupp K, Wang GS, Hopfer C, Kinney G, Bowler R, Foreman N, Galinkin J, Christians U, Klawitter J.

Ther Drug Monit. 2017 Oct;39(5):556-564. doi: 10.1097/FTD.0000000000000427.

25.

Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice.

Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, Ravid K, Choi DS, Wen J, Lukashev D, Blackburn MR, Osswald H, Coe IR, Nürnberg B, Haase VH, Xia Y, Sitkovsky M, Eltzschig HK.

J Clin Invest. 2017 Jun 1;127(6):2438. doi: 10.1172/JCI94890. Epub 2017 Jun 1. No abstract available.

26.

The novel combination of theophylline and bambuterol as a potential treatment of hypoxemia in humans.

Strand TE, Khiabani HZ, Boico A, Radiloff D, Zhao Y, Hamilton KL, Christians U, Klawitter J, Noveck RJ, Piantadosi CA, Bell C, Irwin D, Schroeder T.

Can J Physiol Pharmacol. 2017 Sep;95(9):1009-1018. doi: 10.1139/cjpp-2016-0635. Epub 2017 May 3.

PMID:
28467859
27.

Intrauterine Growth Restriction Programs the Hypothalamus of Adult Male Rats: Integrated Analysis of Proteomic and Metabolomic Data.

Pedroso AP, Souza AP, Dornellas AP, Oyama LM, Nascimento CM, Santos GM, Rosa JC, Bertolla RP, Klawitter J, Christians U, Tashima AK, Ribeiro EB.

J Proteome Res. 2017 Apr 7;16(4):1515-1525. doi: 10.1021/acs.jproteome.6b00923. Epub 2017 Mar 30.

PMID:
28314371
28.

Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells.

Tavera-Mendoza LE, Westerling T, Libby E, Marusyk A, Cato L, Cassani R, Cameron LA, Ficarro SB, Marto JA, Klawitter J, Brown M.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2186-E2194. doi: 10.1073/pnas.1615015114. Epub 2017 Feb 27.

29.

Ablation of Cyclophilin D Results in an Activation of FAK, Akt, and ERK Pathways in the Mouse Heart.

Klawitter J, Seres T, Pennington A, Beatty JT, Klawitter J, Christians U.

J Cell Biochem. 2017 Sep;118(9):2933-2940. doi: 10.1002/jcb.25947. Epub 2017 Apr 12.

PMID:
28230282
30.

Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches.

Checkley W, Deza MP, Klawitter J, Romero KM, Klawitter J, Pollard SL, Wise RA, Christians U, Hansel NN.

Respir Med. 2016 Dec;121:59-66. doi: 10.1016/j.rmed.2016.10.011. Epub 2016 Oct 21.

31.

TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death.

Fritsch J, Fickers R, Klawitter J, Särchen V, Zingler P, Adam D, Janssen O, Krause E, Schütze S.

Oncotarget. 2016 Nov 15;7(46):75774-75789. doi: 10.18632/oncotarget.12411.

32.

Nocturnal hypoxia-induced oxidative stress promotes progression of pediatric non-alcoholic fatty liver disease.

Sundaram SS, Halbower A, Pan Z, Robbins K, Capocelli KE, Klawitter J, Shearn CT, Sokol RJ.

J Hepatol. 2016 Sep;65(3):560-9. doi: 10.1016/j.jhep.2016.04.010. Epub 2016 Aug 5.

33.

Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass.

Davidson JA, Urban T, Tong S, Twite M, Woodruff A, Wischmeyer PE, Klawitter J.

PLoS One. 2016 Jul 6;11(7):e0158981. doi: 10.1371/journal.pone.0158981. eCollection 2016.

34.

Amino acids in a targeted versus a non-targeted metabolomics LC-MS/MS assay. Are the results consistent?

Klepacki J, Klawitter J, Klawitter J, Karimpour-Fard A, Thurman J, Ingle G, Patel D, Christians U.

Clin Biochem. 2016 Sep;49(13-14):955-61. doi: 10.1016/j.clinbiochem.2016.06.002. Epub 2016 Jun 8.

35.

Inhalation of two putative Gulf War toxins by mice.

Repine JE, Wilson P, Elkins N, Klawitter J, Christians U, Peters B, Smith DM.

J Environ Sci Health B. 2016;51(6):366-73. doi: 10.1080/03601234.2016.1142318. Epub 2016 Mar 7. Erratum in: J Environ Sci Health B. 2016 Sep;51(9):654.

PMID:
26950528
36.

In Memoriam--Samuel F. Hulbert, Ph.D., 1936-2016: On January 29th of this year, the world of biomaterials and biomedical engineering lost a true visionary and champion with the passing of Samuel "Sam" Hulbert.

Lemons J, Klawitter J.

J Biomed Mater Res A. 2016 May;104(5):1062-3. doi: 10.1002/jbm.a.35694. Epub 2016 Mar 15. No abstract available.

PMID:
26916662
37.

Development of liquid chromatography-tandem mass spectrometry methods for the quantitation of Anisakis simplex proteins in fish.

Fæste CK, Moen A, Schniedewind B, Haug Anonsen J, Klawitter J, Christians U.

J Chromatogr A. 2016 Feb 5;1432:58-72. doi: 10.1016/j.chroma.2016.01.002. Epub 2016 Jan 6.

PMID:
26787163
38.

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.

Henry CJ, Casás-Selves M, Kim J, Zaberezhnyy V, Aghili L, Daniel AE, Jimenez L, Azam T, McNamee EN, Clambey ET, Klawitter J, Serkova NJ, Tan AC, Dinarello CA, DeGregori J.

J Clin Invest. 2015 Dec;125(12):4666-80. doi: 10.1172/JCI83024. Epub 2015 Nov 9.

39.

Sex Steroids Do Not Modulate TRPM2-Mediated Injury in Females following Middle Cerebral Artery Occlusion(1,2,3).

Quillinan N, Grewal H, Klawitter J, Herson PS.

eNeuro. 2014 Nov 12;1(1). pii: ENEURO.0022-14.2014. doi: 10.1523/ENEURO.0022-14.2014. eCollection 2014 Nov-Dec.

40.

Biomarkers in Transplantation--Proteomics and Metabolomics.

Christians U, Klawitter J, Klawitter J.

Ther Drug Monit. 2016 Apr;38 Suppl 1:S70-4. doi: 10.1097/FTD.0000000000000243. Review.

41.

Pravastatin Therapy and Biomarker Changes in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease.

Klawitter J, McFann K, Pennington AT, Wang W, Klawitter J, Christians U, Schrier RW, Gitomer B, Cadnapaphornchai MA.

Clin J Am Soc Nephrol. 2015 Sep 4;10(9):1534-41. doi: 10.2215/CJN.11331114. Epub 2015 Jul 29.

42.

Everolimus and sirolimus in transplantation-related but different.

Klawitter J, Nashan B, Christians U.

Expert Opin Drug Saf. 2015 Jul;14(7):1055-70. doi: 10.1517/14740338.2015.1040388. Epub 2015 Apr 26. Review.

43.

Effect of dietary sodium restriction on human urinary metabolomic profiles.

Jablonski KL, Klawitter J, Chonchol M, Bassett CJ, Racine ML, Seals DR.

Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1227-34. doi: 10.2215/CJN.11531114. Epub 2015 Apr 21.

44.

A high-performance liquid chromatography-tandem mass spectrometry-based targeted metabolomics kidney dysfunction marker panel in human urine.

Klepacki J, Klawitter J, Klawitter J, Thurman JM, Christians U.

Clin Chim Acta. 2015 Jun 15;446:43-53. doi: 10.1016/j.cca.2015.04.005. Epub 2015 Apr 11.

45.

Endothelial dysfunction and oxidative stress in polycystic kidney disease.

Klawitter J, Reed-Gitomer BY, McFann K, Pennington A, Klawitter J, Abebe KZ, Klepacki J, Cadnapaphornchai MA, Brosnahan G, Chonchol M, Christians U, Schrier RW.

Am J Physiol Renal Physiol. 2014 Dec 1;307(11):F1198-206. doi: 10.1152/ajprenal.00327.2014. Epub 2014 Sep 18.

46.

Fatty acid desaturation index in human plasma: comparison of different analytical methodologies for the evaluation of diet effects.

Klawitter J, Bek S, Zakaria M, Zeng C, Hornberger A, Gilbert R, Shokati T, Klawitter J, Christians U, Boernsen KO.

Anal Bioanal Chem. 2014 Oct;406(25):6399-408. doi: 10.1007/s00216-014-8020-4. Epub 2014 Aug 13.

PMID:
25116600
47.

Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1(+) leukemia.

Gardner LA, Klawitter J, Gregory MA, Zaberezhnyy V, Baturin D, Pollyea DA, Takebe N, Christians U, Gore L, DeGregori J, Porter CC.

Am J Hematol. 2014 Sep;89(9):896-903. doi: 10.1002/ajh.23776. Epub 2014 Jun 19.

48.

Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs.

Fernandez-Bustamante A, Klawitter J, Repine JE, Agazio A, Janocha AJ, Shah C, Moss M, Douglas IS, Tran ZV, Erzurum SC, Christians U, Seres T.

Anesthesiology. 2014 Sep;121(3):469-81. doi: 10.1097/ALN.0000000000000301.

49.

Mycophenolate mofetil enhances the negative effects of sirolimus and tacrolimus on rat kidney cell metabolism.

Klawitter J, Klawitter J, Schmitz V, Shokati T, Epshtein E, Thurman JM, Christians U.

PLoS One. 2014 Jan 30;9(1):e86202. doi: 10.1371/journal.pone.0086202. eCollection 2014.

50.

Bioactive lipid mediators in polycystic kidney disease.

Klawitter J, Klawitter J, McFann K, Pennington AT, Abebe KZ, Brosnahan G, Cadnapaphornchai MA, Chonchol M, Gitomer B, Christians U, Schrier RW.

J Lipid Res. 2014 Jun;55(6):1139-49. doi: 10.1194/jlr.P042176. Epub 2013 Dec 16.

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