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Items: 1 to 50 of 300

1.

Evaluation of a Screening Program to Detect Critical Congenital Heart Defects in Newborns.

Klausner R, Shapiro ED, Elder RW, Colson E, Loyal J.

Hosp Pediatr. 2017 Apr;7(4):214-218. doi: 10.1542/hpeds.2016-0176. Epub 2017 Mar 1.

2.

Next-Generation Sequencing of Circulating Tumor DNA for Early Cancer Detection.

Aravanis AM, Lee M, Klausner RD.

Cell. 2017 Feb 9;168(4):571-574. doi: 10.1016/j.cell.2017.01.030.

3.

Acute nicotine administration increases BOLD fMRI signal in brain regions involved in reward signaling and compulsive drug intake in rats.

Bruijnzeel AW, Alexander JC, Perez PD, Bauzo-Rodriguez R, Hall G, Klausner R, Guerra V, Zeng H, Igari M, Febo M.

Int J Neuropsychopharmacol. 2014 Oct 31;18(2). pii: pyu011. doi: 10.1093/ijnp/pyu011.

4.

Innovating for every woman and every child.

Godal T, Klausner R.

Lancet. 2012 Jan 7;379(9810):e1-2. doi: 10.1016/S0140-6736(11)61393-7. Epub 2011 Sep 9. No abstract available.

PMID:
21908037
5.

Translational science: a view from a biotechnology investor.

Klausner R.

Sci Transl Med. 2010 Jun 2;2(34):34ed3. doi: 10.1126/scitranslmed.3001274. No abstract available.

6.

Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma.

Riss J, Khanna C, Koo S, Chandramouli GV, Yang HH, Hu Y, Kleiner DE, Rosenwald A, Schaefer CF, Ben-Sasson SA, Yang L, Powell J, Kane DW, Star RA, Aprelikova O, Bauer K, Vasselli JR, Maranchie JK, Kohn KW, Buetow KH, Linehan WM, Weinstein JN, Lee MP, Klausner RD, Barrett JC.

Cancer Res. 2006 Jul 15;66(14):7216-24.

7.

Perspective from the National Cancer Institute (NCI).

Liu E, Nealon E, Klausner R.

Breast Dis. 1998 Dec;10(5-6):29-31. No abstract available.

PMID:
15687583
8.

Breast disease. Foreword.

Klausner R.

Breast Dis. 1998 Apr;10(1-2):1. No abstract available.

PMID:
15687542
9.

An attack on all fronts.

Klausner R, Alonso P.

Nature. 2004 Aug 19;430(7002):930-1. No abstract available.

PMID:
15318232
10.

An audience with... Richard D. Klausner.

Klausner RD.

Nat Rev Drug Discov. 2004 Jun;3(6):470. No abstract available.

PMID:
15214330
11.

Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location.

Maranchie JK, Afonso A, Albert PS, Kalyandrug S, Phillips JL, Zhou S, Peterson J, Ghadimi BM, Hurley K, Riss J, Vasselli JR, Ried T, Zbar B, Choyke P, Walther MM, Klausner RD, Linehan WM.

Hum Mutat. 2004 Jan;23(1):40-6.

PMID:
14695531
12.

Public health. Grand Challenges in Global Health.

Varmus H, Klausner R, Zerhouni E, Acharya T, Daar AS, Singer PA.

Science. 2003 Oct 17;302(5644):398-9.

13.

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma.

Rosenwald A, Wright G, Leroy K, Yu X, Gaulard P, Gascoyne RD, Chan WC, Zhao T, Haioun C, Greiner TC, Weisenburger DD, Lynch JC, Vose J, Armitage JO, Smeland EB, Kvaloy S, Holte H, Delabie J, Campo E, Montserrat E, Lopez-Guillermo A, Ott G, Muller-Hermelink HK, Connors JM, Braziel R, Grogan TM, Fisher RI, Miller TP, LeBlanc M, Chiorazzi M, Zhao H, Yang L, Powell J, Wilson WH, Jaffe ES, Simon R, Klausner RD, Staudt LM.

J Exp Med. 2003 Sep 15;198(6):851-62.

14.

Medicine. The need for a global HIV vaccine enterprise.

Klausner RD, Fauci AS, Corey L, Nabel GJ, Gayle H, Berkley S, Haynes BF, Baltimore D, Collins C, Douglas RG, Esparza J, Francis DP, Ganguly NK, Gerberding JL, Johnston MI, Kazatchkine MD, McMichael AJ, Makgoba MW, Pantaleo G, Piot P, Shao Y, Tramont E, Varmus H, Wasserheit JN.

Science. 2003 Jun 27;300(5628):2036-9.

PMID:
12829768
15.

Predicting survival in patients with metastatic kidney cancer by gene-expression profiling in the primary tumor.

Vasselli JR, Shih JH, Iyengar SR, Maranchie J, Riss J, Worrell R, Torres-Cabala C, Tabios R, Mariotti A, Stearman R, Merino M, Walther MM, Simon R, Klausner RD, Linehan WM.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):6958-63. Epub 2003 May 30.

16.

The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma.

Rosenwald A, Wright G, Wiestner A, Chan WC, Connors JM, Campo E, Gascoyne RD, Grogan TM, Muller-Hermelink HK, Smeland EB, Chiorazzi M, Giltnane JM, Hurt EM, Zhao H, Averett L, Henrickson S, Yang L, Powell J, Wilson WH, Jaffe ES, Simon R, Klausner RD, Montserrat E, Bosch F, Greiner TC, Weisenburger DD, Sanger WG, Dave BJ, Lynch JC, Vose J, Armitage JO, Fisher RI, Miller TP, LeBlanc M, Ott G, Kvaloy S, Holte H, Delabie J, Staudt LM.

Cancer Cell. 2003 Feb;3(2):185-97.

17.

Studying cancer families to identify kidney cancer genes.

Zbar B, Klausner R, Linehan WM.

Annu Rev Med. 2003;54:217-33. Epub 2001 Dec 3. Review.

PMID:
12525673
18.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA; Mammalian Gene Collection Program Team.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

19.

Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.

Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10353-8. Epub 2002 Jul 29.

20.

The fabric of cancer cell biology-Weaving together the strands.

Klausner RD.

Cancer Cell. 2002 Feb;1(1):3-10. Review. No abstract available.

21.

The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma.

Maranchie JK, Vasselli JR, Riss J, Bonifacino JS, Linehan WM, Klausner RD.

Cancer Cell. 2002 Apr;1(3):247-55.

22.

Cancer Molecular Analysis Project: weaving a rich cancer research tapestry.

Buetow KH, Klausner RD, Fine H, Kaplan R, Singer DS, Strausberg RL.

Cancer Cell. 2002 May;1(4):315-8. Review.

23.

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma.

Rosenwald A, Wright G, Chan WC, Connors JM, Campo E, Fisher RI, Gascoyne RD, Muller-Hermelink HK, Smeland EB, Giltnane JM, Hurt EM, Zhao H, Averett L, Yang L, Wilson WH, Jaffe ES, Simon R, Klausner RD, Powell J, Duffey PL, Longo DL, Greiner TC, Weisenburger DD, Sanger WG, Dave BJ, Lynch JC, Vose J, Armitage JO, Montserrat E, López-Guillermo A, Grogan TM, Miller TP, LeBlanc M, Ott G, Kvaloy S, Delabie J, Holte H, Krajci P, Stokke T, Staudt LM; Lymphoma/Leukemia Molecular Profiling Project.

N Engl J Med. 2002 Jun 20;346(25):1937-47.

24.

VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells.

Bindra RS, Vasselli JR, Stearman R, Linehan WM, Klausner RD.

Cancer Res. 2002 Jun 1;62(11):3014-9.

25.

Reductive iron uptake by Candida albicans: role of copper, iron and the TUP1 regulator.

Knight SA, Lesuisse E, Stearman R, Klausner RD, Dancis A.

Microbiology. 2002 Jan;148(Pt 1):29-40.

PMID:
11782496
26.

Biomedicine. The NASA-NCI collaboration on biomolecular sensors.

Goldin DS, Dahl CA, Olsen KL, Ostrach LH, Klausner RD.

Science. 2001 Apr 20;292(5516):443-4. No abstract available.

PMID:
11330296
27.

Molecular cytogenetic characterization of early and late renal cell carcinomas in von Hippel-Lindau disease.

Phillips JL, Ghadimi BM, Wangsa D, Padilla-Nash H, Worrell R, Hewitt S, Walther M, Linehan WM, Klausner RD, Ried T.

Genes Chromosomes Cancer. 2001 May;31(1):1-9.

PMID:
11284029
28.

Molecular profiling of clinical tissues specimens: feasibility and applications.

Emmert-Buck MR, Strausberg RL, Krizman DB, Bonaldo MF, Bonner RF, Bostwick DG, Brown MR, Buetow KH, Chuaqui RF, Cole KA, Duray PH, Englert CR, Gillespie JW, Greenhut S, Grouse L, Hillier LW, Katz KS, Klausner RD, Kuznetzov V, Lash AE, Lennon G, Linehan WM, Liotta LA, Marra MA, Munson PJ, Ornstein DK, Prabhu VV, Prang C, Schuler GD, Soares MB, Tolstoshev CM, Vocke CD, Waterston RH.

J Mol Diagn. 2000 May;2(2):60-6. Review. No abstract available.

29.

Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis.

de Paulsen N, Brychzy A, Fournier MC, Klausner RD, Gnarra JR, Pause A, Lee S.

Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1387-92. Epub 2001 Feb 6.

30.

Foreword

Klausner RD.

J Natl Cancer Inst Monogr. 1999;(25):1. No abstract available.

PMID:
10854445
31.

Molecular profiling of clinical tissue specimens: feasibility and applications.

Emmert-Buck MR, Strausberg RL, Krizman DB, Bonaldo MF, Bonner RF, Bostwick DG, Brown MR, Buetow KH, Chuaqui RF, Cole KA, Duray PH, Englert CR, Gillespie JW, Greenhut S, Grouse L, Hillier LW, Katz KS, Klausner RD, Kuznetzov V, Lash AE, Lennon G, Linehan WM, Liotta LA, Marra MA, Munson PJ, Ornstein DK, Prabhu VV, Prange C, Schuler GD, Soares MB, Tolstoshev CM, Vocke CD, Waterston RH.

Am J Pathol. 2000 Apr;156(4):1109-15. Review. No abstract available.

32.

A systematic, high-resolution linkage of the cytogenetic and physical maps of the human genome.

Kirsch IR, Green ED, Yonescu R, Strausberg R, Carter N, Bentley D, Leversha MA, Dunham I, Braden VV, Hilgenfeld E, Schuler G, Lash AE, Shen GL, Martelli M, Kuehl WM, Klausner RD, Ried T.

Nat Genet. 2000 Apr;24(4):339-40. No abstract available.

PMID:
10742091
33.

The cancer genome anatomy project: building an annotated gene index.

Strausberg RL, Buetow KH, Emmert-Buck MR, Klausner RD.

Trends Genet. 2000 Mar;16(3):103-6. No abstract available.

PMID:
10689348
34.

Constitutional von Hippel-Lindau (VHL) gene deletions detected in VHL families by fluorescence in situ hybridization.

Pack SD, Zbar B, Pak E, Ault DO, Humphrey JS, Pham T, Hurley K, Weil RJ, Park WS, Kuzmin I, Stolle C, Glenn G, Liotta LA, Lerman MI, Klausner RD, Linehan WM, Zhuang Z.

Cancer Res. 1999 Nov 1;59(21):5560-4.

35.

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.

Iwai K, Yamanaka K, Kamura T, Minato N, Conaway RC, Conaway JW, Klausner RD, Pause A.

Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12436-41.

36.

The mammalian gene collection.

Strausberg RL, Feingold EA, Klausner RD, Collins FS.

Science. 1999 Oct 15;286(5439):455-7.

PMID:
10521335
37.

Studying cancer in the mouse.

Klausner RD.

Oncogene. 1999 Sep 20;18(38):5249-52. Review. No abstract available.

38.

The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells.

Koochekpour S, Jeffers M, Wang PH, Gong C, Taylor GA, Roessler LM, Stearman R, Vasselli JR, Stetler-Stevenson WG, Kaelin WG Jr, Linehan WM, Klausner RD, Gnarra JR, Vande Woude GF.

Mol Cell Biol. 1999 Sep;19(9):5902-12.

39.

Cancer, genomics, and the National Cancer Institute.

Klausner RD.

J Clin Invest. 1999;104 Suppl:S15-7. No abstract available.

PMID:
10453252
41.

Tenth Annual Pezcoller Symposium: the genetics of cancer susceptibility.

Mihich E, Strong L, Klausner R.

Cancer Res. 1999 Jul 1;59(13):3271-9. No abstract available.

42.

Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein.

Lee S, Neumann M, Stearman R, Stauber R, Pause A, Pavlakis GN, Klausner RD.

Mol Cell Biol. 1999 Feb;19(2):1486-97.

43.

Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor gene.

Stolle C, Glenn G, Zbar B, Humphrey JS, Choyke P, Walther M, Pack S, Hurley K, Andrey C, Klausner R, Linehan WM.

Hum Mutat. 1998;12(6):417-23.

PMID:
9829911
44.

'Breast cancer prevention trial'.

Klausner RD.

Jpn J Clin Oncol. 1998 Jul;28(7):459-60. No abstract available.

PMID:
9739790
45.

Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast.

Philpott CC, Rashford J, Yamaguchi-Iwai Y, Rouault TA, Dancis A, Klausner RD.

EMBO J. 1998 Sep 1;17(17):5026-36.

46.

Identification of a putative alpha-glucan synthase essential for cell wall construction and morphogenesis in fission yeast.

Hochstenbach F, Klis FM, van den Ende H, van Donselaar E, Peters PJ, Klausner RD.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9161-6.

47.

Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins.

Iwai K, Drake SK, Wehr NB, Weissman AM, LaVaute T, Minato N, Klausner RD, Levine RL, Rouault TA.

Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):4924-8.

48.

YIpDCE1 - an integrating plasmid for dual constitutive expression in yeast.

Stearman R, Dancis A, Klausner RD.

Gene. 1998 Jun 8;212(2):197-202.

PMID:
9611262
49.

The yeast CLC chloride channel functions in cation homeostasis.

Gaxiola RA, Yuan DS, Klausner RD, Fink GR.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4046-50.

50.

The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal.

Pause A, Lee S, Lonergan KM, Klausner RD.

Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):993-8.

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