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Items: 23

1.
2.

Randomized placebo-controlled dose-ranging and pharmacodynamics study of roxadustat (FG-4592) to treat anemia in nondialysis-dependent chronic kidney disease (NDD-CKD) patients.

Besarab A, Provenzano R, Hertel J, Zabaneh R, Klaus SJ, Lee T, Leong R, Hemmerich S, Yu KH, Neff TB.

Nephrol Dial Transplant. 2015 Oct;30(10):1665-73. doi: 10.1093/ndt/gfv302. Epub 2015 Aug 3.

3.

Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization.

Paliege A, Rosenberger C, Bondke A, Sciesielski L, Shina A, Heyman SN, Flippin LA, Arend M, Klaus SJ, Bachmann S.

Kidney Int. 2010 Feb;77(4):312-8. doi: 10.1038/ki.2009.460. Epub 2009 Dec 16.

4.

Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney.

Rosenberger C, Rosen S, Shina A, Frei U, Eckardt KU, Flippin LA, Arend M, Klaus SJ, Heyman SN.

Nephrol Dial Transplant. 2008 Nov;23(11):3472-8. doi: 10.1093/ndt/gfn276. Epub 2008 May 29.

PMID:
18515655
5.

An endoplasmic reticulum transmembrane prolyl 4-hydroxylase is induced by hypoxia and acts on hypoxia-inducible factor alpha.

Koivunen P, Tiainen P, Hyvärinen J, Williams KE, Sormunen R, Klaus SJ, Kivirikko KI, Myllyharju J.

J Biol Chem. 2007 Oct 19;282(42):30544-52. Epub 2007 Aug 27.

6.

HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques.

Hsieh MM, Linde NS, Wynter A, Metzger M, Wong C, Langsetmo I, Lin A, Smith R, Rodgers GP, Donahue RE, Klaus SJ, Tisdale JF.

Blood. 2007 Sep 15;110(6):2140-7. Epub 2007 Jun 8.

7.
8.

Amelioration of CR-EAE with lisofylline: effects on mRNA levels of IL-12 and IFN-gamma in the CNS.

Du C, Cooper JC, Klaus SJ, Sriram S.

J Neuroimmunol. 2000 Oct 2;110(1-2):13-9.

PMID:
11024530
9.

Selective pharmacologic inhibition of murine and human IL-12-dependent Th1 differentiation and IL-12 signaling.

Coon ME, Diegel M, Leshinsky N, Klaus SJ.

J Immunol. 1999 Dec 15;163(12):6567-74.

11.

CD22 regulates thymus-independent responses and the lifespan of B cells.

Otipoby KL, Andersson KB, Draves KE, Klaus SJ, Farr AG, Kerner JD, Perlmutter RM, Law CL, Clark EA.

Nature. 1996 Dec 19-26;384(6610):634-7.

PMID:
8967951
12.

Functional CD40 ligand expressed by human blood dendritic cells is up-regulated by CD40 ligation.

Pinchuk LM, Klaus SJ, Magaletti DM, Pinchuk GV, Norsen JP, Clark EA.

J Immunol. 1996 Nov 15;157(10):4363-70.

PMID:
8906811
13.

Regulation of signalling through B-lymphocyte antigen receptors by cell-cell interaction molecules.

Law CL, Craxton A, Otipoby KL, Sidorenko SP, Klaus SJ, Clark EC.

Immunol Rev. 1996 Oct;153:123-54. Review. No abstract available.

PMID:
9010722
14.

Protein kinase C mu (PKC mu) associates with the B cell antigen receptor complex and regulates lymphocyte signaling.

Sidorenko SP, Law CL, Klaus SJ, Chandran KA, Takata M, Kurosaki T, Clark EA.

Immunity. 1996 Oct;5(4):353-63.

15.

CD45 ligation induces programmed cell death in T and B lymphocytes.

Klaus SJ, Sidorenko SP, Clark EA.

J Immunol. 1996 Apr 15;156(8):2743-53.

PMID:
8609392
16.

Cell-cell interactions regulate dendritic cell-dependent HIV-1 production in CD4+ T lymphocytes.

Pinchuk LM, Polacino PS, Agy MB, Klaus SJ, Clark EA.

Adv Exp Med Biol. 1995;378:461-3.

PMID:
8526118
17.

CD40 and its ligand in the regulation of humoral immunity.

Klaus SJ, Berberich I, Shu G, Clark EA.

Semin Immunol. 1994 Oct;6(5):279-86. Review.

PMID:
7532458
18.

The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection.

Pinchuk LM, Polacino PS, Agy MB, Klaus SJ, Clark EA.

Immunity. 1994 Jul;1(4):317-25.

PMID:
7534204
19.

Costimulation through CD28 enhances T cell-dependent B cell activation via CD40-CD40L interaction.

Klaus SJ, Pinchuk LM, Ochs HD, Law CL, Fanslow WC, Armitage RJ, Clark EA.

J Immunol. 1994 Jun 15;152(12):5643-52.

PMID:
7515910
20.

Accessory molecules that influence signaling through B lymphocyte antigen receptors.

Clark EA, Berberich I, Klaus SJ, Law CL, Sidorenko SP.

Adv Exp Med Biol. 1994;365:35-43. No abstract available.

PMID:
7887311
22.

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