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Items: 1 to 50 of 321

1.

On the therapeutic scope of low-dose IL-2. Response to: 'Circulating regulatory T cells were absolutelydecreased in dermatomyositis/polymyositispatients and restored by low-dose IL-2' by Zhang et al.

Klatzmann D.

Ann Rheum Dis. 2019 Oct 14. pii: annrheumdis-2019-216267. doi: 10.1136/annrheumdis-2019-216267. [Epub ahead of print] No abstract available.

PMID:
31611217
2.

Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells.

Pouzolles M, Machado A, Guilbaud M, Irla M, Gailhac S, Barennes P, Cesana D, Calabria A, Benedicenti F, Sergé A, Raman I, Li QZ, Montini E, Klatzmann D, Adjali O, Taylor N, Zimmermann VS.

J Allergy Clin Immunol. 2019 Sep 9. pii: S0091-6749(19)31171-6. doi: 10.1016/j.jaci.2019.08.029. [Epub ahead of print]

PMID:
31513879
3.

T regulatory cells activation and distribution are modified in critically ill patients with acute respiratory distress syndrome: A prospective single-centre observational study.

Halter S, Aimade L, Barbié M, Brisson H, Rouby JJ, Langeron O, Klatzmann D, Rosenzwajg M, Monsel A.

Anaesth Crit Care Pain Med. 2019 Jul 30. pii: S2352-5568(19)30210-3. doi: 10.1016/j.accpm.2019.07.014. [Epub ahead of print]

PMID:
31374365
4.

TLR9 signalling in HCV-associated atypical memory B cells triggers Th1 and rheumatoid factor autoantibody responses.

Comarmond C, Lorin V, Marques C, Maciejewski-Duval A, Joher N, Planchais C, Touzot M, Biard L, Hieu T, Quiniou V, Desbois AC, Rosenzwajg M, Klatzmann D, Cacoub P, Mouquet H, Saadoun D.

J Hepatol. 2019 Nov;71(5):908-919. doi: 10.1016/j.jhep.2019.06.029. Epub 2019 Jul 4.

PMID:
31279905
5.

Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells.

Ritvo PG, Klatzmann D.

Front Immunol. 2019 Feb 27;10:250. doi: 10.3389/fimmu.2019.00250. eCollection 2019. Review.

6.

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.

Serradell MC, Rupil LL, Martino RA, Prucca CG, Carranza PG, Saura A, Fernández EA, Gargantini PR, Tenaglia AH, Petiti JP, Tonelli RR, Reinoso-Vizcaino N, Echenique J, Berod L, Piaggio E, Bellier B, Sparwasser T, Klatzmann D, Luján HD.

Nat Commun. 2019 Jan 21;10(1):361. doi: 10.1038/s41467-018-08265-9.

7.

Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial.

Rosenzwajg M, Lorenzon R, Cacoub P, Pham HP, Pitoiset F, El Soufi K, RIbet C, Bernard C, Aractingi S, Banneville B, Beaugerie L, Berenbaum F, Champey J, Chazouilleres O, Corpechot C, Fautrel B, Mekinian A, Regnier E, Saadoun D, Salem JE, Sellam J, Seksik P, Daguenel-Nguyen A, Doppler V, Mariau J, Vicaut E, Klatzmann D.

Ann Rheum Dis. 2019 Feb;78(2):209-217. doi: 10.1136/annrheumdis-2018-214229. Epub 2018 Nov 24.

PMID:
30472651
8.

Role of Chemokine Receptor CCR4 and Regulatory T Cells in Wound Healing of Diabetic Mice.

Barros JF, Waclawiak I, Pecli C, Borges PA, Georgii JL, Ramos-Junior ES, Canetti C, Courau T, Klatzmann D, Kunkel SL, Penido C, Canto FB, Benjamim CF.

J Invest Dermatol. 2019 May;139(5):1161-1170. doi: 10.1016/j.jid.2018.10.039. Epub 2018 Nov 19.

PMID:
30465800
9.

Comparison of Dendritic Cell Activation by Virus-Based Vaccine Delivery Vectors Emphasizes the Transcriptional Downregulation of the Oxidative Phosphorylation Pathway.

Tsitoura E, Kazazi D, Oz-Arslan D, Sever EA, Khalili S, Vassilaki N, Aslanoglou E, Dérian N, Six A, Sezerman OU, Klatzmann D, Mavromara P.

Hum Gene Ther. 2019 Apr;30(4):429-445. doi: 10.1089/hum.2018.161. Epub 2019 Jan 25.

PMID:
30351174
10.

Regulatory T cells in the treatment of disease.

Sharabi A, Tsokos MG, Ding Y, Malek TR, Klatzmann D, Tsokos GC.

Nat Rev Drug Discov. 2018 Nov;17(11):823-844. doi: 10.1038/nrd.2018.148. Epub 2018 Oct 12. Review.

PMID:
30310234
11.

Deep phenotyping of immune cell populations by optimized and standardized flow cytometry analyses.

Pitoiset F, Cassard L, El Soufi K, Boselli L, Grivel J, Roux A, Klatzmann D, Chaput N, Rosenzwajg M.

Cytometry A. 2018 Aug;93(8):793-802. doi: 10.1002/cyto.a.23570. Epub 2018 Aug 31.

12.

Clinical and multi-omics cross-phenotyping of patients with autoimmune and autoinflammatory diseases: the observational TRANSIMMUNOM protocol.

Lorenzon R, Mariotti-Ferrandiz E, Aheng C, Ribet C, Toumi F, Pitoiset F, Chaara W, Derian N, Johanet C, Drakos I, Harris S, Amselem S, Berenbaum F, Benveniste O, Bodaghi B, Cacoub P, Grateau G, Amouyal C, Hartemann A, Saadoun D, Sellam J, Seksik P, Sokol H, Salem JE, Vicaut E, Six A, Rosenzwajg M, Bernard C, Klatzmann D.

BMJ Open. 2018 Aug 30;8(8):e021037. doi: 10.1136/bmjopen-2017-021037.

13.

Immunological environment in colorectal cancer: a computer-aided morphometric study of whole slide digital images derived from tissue microarray.

Eyraud D, Granger B, Bardier A, Loncar Y, Gottrand G, Le Naour G, Siksik JM, Vaillant JC, Klatzmann D, Puybasset L, Charlotte F, Augustin J.

Pathology. 2018 Oct;50(6):607-612. doi: 10.1016/j.pathol.2018.04.006. Epub 2018 Aug 27.

PMID:
30166125
14.

High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells.

Ritvo PG, Saadawi A, Barennes P, Quiniou V, Chaara W, El Soufi K, Bonnet B, Six A, Shugay M, Mariotti-Ferrandiz E, Klatzmann D.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9604-9609. doi: 10.1073/pnas.1808594115. Epub 2018 Aug 29.

15.

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.

Zacchigna S, Martinelli V, Moimas S, Colliva A, Anzini M, Nordio A, Costa A, Rehman M, Vodret S, Pierro C, Colussi G, Zentilin L, Gutierrez MI, Dirkx E, Long C, Sinagra G, Klatzmann D, Giacca M.

Nat Commun. 2018 Jun 26;9(1):2432. doi: 10.1038/s41467-018-04908-z.

16.

Pharmacodynamics of regulatory T cells in mice and humans treated with low-dose IL-2.

Churlaud G, Abbara C, Vinot PA, Fourcade G, Ritvo PG, Lorenzon R, Rosenzwajg M, Diquet B, Klatzmann D.

J Allergy Clin Immunol. 2018 Oct;142(4):1344-1346.e3. doi: 10.1016/j.jaci.2018.06.006. Epub 2018 Jun 18. No abstract available.

17.

RepSeq Data Representativeness and Robustness Assessment by Shannon Entropy.

Chaara W, Gonzalez-Tort A, Florez LM, Klatzmann D, Mariotti-Ferrandiz E, Six A.

Front Immunol. 2018 May 15;9:1038. doi: 10.3389/fimmu.2018.01038. eCollection 2018.

18.

IL-2 antibodies in type 1 diabetes and during IL-2 therapy.

Churlaud G, Rosenzwajg M, Cacoub P, Saadoun D, Valteau-Couanet D, Chaput N, Pugliese A, Klatzmann D.

Diabetologia. 2018 Sep;61(9):2066-2068. doi: 10.1007/s00125-018-4649-4. Epub 2018 Jun 2. No abstract available.

PMID:
29860627
19.

Activated dendritic cells modulate proliferation and differentiation of human myoblasts.

Ladislau L, Portilho DM, Courau T, Solares-Pérez A, Negroni E, Lainé J, Klatzmann D, Bonomo A, Allenbach Y, Benveniste O, Riederer I, Savino W, Mouly V, Butler-Browne G, Benjamim CF.

Cell Death Dis. 2018 May 1;9(5):551. doi: 10.1038/s41419-018-0426-z.

20.

Regulatory T Cells As Supporters of Psychoimmune Resilience: Toward Immunotherapy of Major Depressive Disorder.

Ellul P, Mariotti-Ferrandiz E, Leboyer M, Klatzmann D.

Front Neurol. 2018 Mar 20;9:167. doi: 10.3389/fneur.2018.00167. eCollection 2018.

21.

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, Cuturi MC, Geissler E, Giannoukakis N, Gołab K, Hafler DA, van Ham SM, Hester J, Hippen K, Di Ianni M, Ilic N, Isaacs J, Issa F, Iwaszkiewicz-Grześ D, Jaeckel E, Joosten I, Klatzmann D, Koenen H, van Kooten C, Korsgren O, Kretschmer K, Levings M, Marek-Trzonkowska NM, Martinez-Llordella M, Miljkovic D, Mills KHG, Miranda JP, Piccirillo CA, Putnam AL, Ritter T, Roncarolo MG, Sakaguchi S, Sánchez-Ramón S, Sawitzki B, Sofronic-Milosavljevic L, Sykes M, Tang Q, Vives-Pi M, Waldmann H, Witkowski P, Wood KJ, Gregori S, Hilkens CMU, Lombardi G, Lord P, Martinez-Caceres EM, Trzonkowski P.

Front Immunol. 2018 Jan 15;8:1844. doi: 10.3389/fimmu.2017.01844. eCollection 2017.

22.

A standardized flow cytometry procedure for the monitoring of regulatory T cells in clinical trials.

Pitoiset F, Barbié M, Monneret G, Braudeau C, Pochard P, Pellegrin I, Trauet J, Labalette M, Klatzmann D, Rosenzwajg M.

Cytometry B Clin Cytom. 2018 Sep;94(5):621-626. doi: 10.1002/cyto.b.21622. Epub 2018 Jan 23.

23.

Reproducibility and Reuse of Adaptive Immune Receptor Repertoire Data.

Breden F, Luning Prak ET, Peters B, Rubelt F, Schramm CA, Busse CE, Vander Heiden JA, Christley S, Bukhari SAC, Thorogood A, Matsen Iv FA, Wine Y, Laserson U, Klatzmann D, Douek DC, Lefranc MP, Collins AM, Bubela T, Kleinstein SH, Watson CT, Cowell LG, Scott JK, Kepler TB.

Front Immunol. 2017 Nov 1;8:1418. doi: 10.3389/fimmu.2017.01418. eCollection 2017.

24.

A Sophism in Vectorology: Turning Harmful Defective Retroviral Vectors into Helpful Replication-Competent Retroviruses Against Cancer.

Klatzmann D.

Hum Gene Ther. 2017 Nov;28(11):954-957. doi: 10.1089/hum.2017.29050.dkl. No abstract available.

PMID:
29035117
25.

Tfr cells lack IL-2Rα but express decoy IL-1R2 and IL-1Ra and suppress the IL-1-dependent activation of Tfh cells.

Ritvo PG, Churlaud G, Quiniou V, Florez L, Brimaud F, Fourcade G, Mariotti-Ferrandiz E, Klatzmann D.

Sci Immunol. 2017 Sep 8;2(15). pii: eaan0368. doi: 10.1126/sciimmunol.aan0368.

PMID:
28887367
26.

Retrovirus-Based Virus-Like Particle Immunogenicity and Its Modulation by Toll-Like Receptor Activation.

Pitoiset F, Vazquez T, Levacher B, Nehar-Belaid D, Dérian N, Vigneron J, Klatzmann D, Bellier B.

J Virol. 2017 Oct 13;91(21). pii: e01230-17. doi: 10.1128/JVI.01230-17. Print 2017 Nov 1.

27.

The early pregnancy placenta foreshadows DNA methylation alterations of solid tumors.

Nordor AV, Nehar-Belaid D, Richon S, Klatzmann D, Bellet D, Dangles-Marie V, Fournier T, Aryee MJ.

Epigenetics. 2017 Sep;12(9):793-803. doi: 10.1080/15592294.2017.1342912. Epub 2017 Nov 24.

28.

Reply: Beneficial effect of interleukin-2-based immunomodulation in Alzheimer-like pathology.

Alves S, Churlaud G, Klatzmann D, Cartier N.

Brain. 2017 Jul 1;140(7):e40. doi: 10.1093/brain/awx109. No abstract available.

PMID:
28498902
29.

Regulatory T Cell Therapy for Uveitis: A New Promising Challenge.

Foussat A, Gregoire S, Clerget-Chossat N, Terrada C, Asnagli H, Lemoine FM, Klatzmann D, LeHoang P, Forte M, Bodaghi B.

J Ocul Pharmacol Ther. 2017 May;33(4):278-284. doi: 10.1089/jop.2016.0165. Review.

PMID:
28448237
30.

T follicular helper and T follicular regulatory cells have different TCR specificity.

Maceiras AR, Almeida SCP, Mariotti-Ferrandiz E, Chaara W, Jebbawi F, Six A, Hori S, Klatzmann D, Faro J, Graca L.

Nat Commun. 2017 Apr 21;8:15067. doi: 10.1038/ncomms15067.

31.

Effect of intracoronary administration of AAV1/SERCA2a on ventricular remodelling in patients with advanced systolic heart failure: results from the AGENT-HF randomized phase 2 trial.

Hulot JS, Salem JE, Redheuil A, Collet JP, Varnous S, Jourdain P, Logeart D, Gandjbakhch E, Bernard C, Hatem SN, Isnard R, Cluzel P, Le Feuvre C, Leprince P, Hammoudi N, Lemoine FM, Klatzmann D, Vicaut E, Komajda M, Montalescot G, Lompré AM, Hajjar RJ; AGENT-HF Investigators.

Eur J Heart Fail. 2017 Nov;19(11):1534-1541. doi: 10.1002/ejhf.826. Epub 2017 Apr 10.

32.

B- and T-cell subpopulations in patients with severe idiopathic membranous nephropathy may predict an early response to rituximab.

Rosenzwajg M, Languille E, Debiec H, Hygino J, Dahan K, Simon T, Klatzmann D, Ronco P.

Kidney Int. 2017 Jul;92(1):227-237. doi: 10.1016/j.kint.2017.01.012. Epub 2017 Mar 15.

PMID:
28318628
33.

T cells and autoimmune kidney disease.

Suárez-Fueyo A, Bradley SJ, Klatzmann D, Tsokos GC.

Nat Rev Nephrol. 2017 Jun;13(6):329-343. doi: 10.1038/nrneph.2017.34. Epub 2017 Mar 13. Review.

PMID:
28287110
34.

Direct-Acting Antiviral Therapy Restores Immune Tolerance to Patients With Hepatitis C Virus-Induced Cryoglobulinemia Vasculitis.

Comarmond C, Garrido M, Pol S, Desbois AC, Costopoulos M, Le Garff-Tavernier M, Si Ahmed SN, Alric L, Fontaine H, Bellier B, Maciejewski A, Rosenzwajg M, Klatzmann D, Musset L, Poynard T, Cacoub P, Saadoun D.

Gastroenterology. 2017 Jun;152(8):2052-2062.e2. doi: 10.1053/j.gastro.2017.02.037. Epub 2017 Mar 6.

PMID:
28274850
35.

Narcolepsy Type 1 Is Associated with a Systemic Increase and Activation of Regulatory T Cells and with a Systemic Activation of Global T Cells.

Lecendreux M, Churlaud G, Pitoiset F, Regnault A, Tran TA, Liblau R, Klatzmann D, Rosenzwajg M.

PLoS One. 2017 Jan 20;12(1):e0169836. doi: 10.1371/journal.pone.0169836. eCollection 2017.

36.

Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice.

Alves S, Churlaud G, Audrain M, Michaelsen-Preusse K, Fol R, Souchet B, Braudeau J, Korte M, Klatzmann D, Cartier N.

Brain. 2017 Mar 1;140(3):826-842. doi: 10.1093/brain/aww330.

PMID:
28003243
37.

The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammation.

Mascarell L, Airouche S, Berjont N, Gary C, Gueguen C, Fourcade G, Bellier B, Togbe D, Ryffel B, Klatzmann D, Baron-Bodo V, Moingeon P.

Mucosal Immunol. 2017 May;10(3):695-704. doi: 10.1038/mi.2016.87. Epub 2016 Oct 12.

PMID:
27731323
38.

TGF-β and VEGF cooperatively control the immunotolerant tumor environment and the efficacy of cancer immunotherapies.

Courau T, Nehar-Belaid D, Florez L, Levacher B, Vazquez T, Brimaud F, Bellier B, Klatzmann D.

JCI Insight. 2016 Jun 16;1(9):e85974. doi: 10.1172/jci.insight.85974.

39.

Molecular signatures of neural connectivity in the olfactory cortex.

Diodato A, Ruinart de Brimont M, Yim YS, Derian N, Perrin S, Pouch J, Klatzmann D, Garel S, Choi GB, Fleischmann A.

Nat Commun. 2016 Jul 18;7:12238. doi: 10.1038/ncomms12238.

40.

Low-Dose IL-2 Induces Regulatory T Cell-Mediated Control of Experimental Food Allergy.

Bonnet B, Vigneron J, Levacher B, Vazquez T, Pitoiset F, Brimaud F, Churlaud G, Klatzmann D, Bellier B.

J Immunol. 2016 Jul 1;197(1):188-98. doi: 10.4049/jimmunol.1501271. Epub 2016 Jun 3.

41.

Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.

Dragin N, Bismuth J, Cizeron-Clairac G, Biferi MG, Berthault C, Serraf A, Nottin R, Klatzmann D, Cumano A, Barkats M, Le Panse R, Berrih-Aknin S.

J Clin Invest. 2016 Apr 1;126(4):1525-37. doi: 10.1172/JCI81894. Epub 2016 Mar 21.

42.

Early Transcriptome Signatures from Immunized Mouse Dendritic Cells Predict Late Vaccine-Induced T-Cell Responses.

Dérian N, Bellier B, Pham HP, Tsitoura E, Kazazi D, Huret C, Mavromara P, Klatzmann D, Six A.

PLoS Comput Biol. 2016 Mar 21;12(3):e1004801. doi: 10.1371/journal.pcbi.1004801. eCollection 2016 Mar.

43.

Behçet's disease physiopathology: a contemporary review.

Zeidan MJ, Saadoun D, Garrido M, Klatzmann D, Six A, Cacoub P.

Auto Immun Highlights. 2016 Dec;7(1):4. doi: 10.1007/s13317-016-0074-1. Epub 2016 Feb 12.

44.

A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria.

Mariotti-Ferrandiz E, Pham HP, Dulauroy S, Gorgette O, Klatzmann D, Cazenave PA, Pied S, Six A.

PLoS One. 2016 Feb 4;11(2):e0147871. doi: 10.1371/journal.pone.0147871. eCollection 2016.

45.

Treatment of Uveitis by In Situ Administration of Ex Vivo-Activated Polyclonal Regulatory T Cells.

Grégoire S, Terrada C, Martin GH, Fourcade G, Baeyens A, Marodon G, Fisson S, Billiard F, Lucas B, Tadayoni R, Béhar-Cohen F, Levacher B, Galy A, LeHoang P, Klatzmann D, Bodaghi B, Salomon BL.

J Immunol. 2016 Mar 1;196(5):2109-18. doi: 10.4049/jimmunol.1501723. Epub 2016 Jan 29.

46.

Tetraspanins displayed in retrovirus-derived virus-like particles and their immunogenicity.

Soares HR, Castro R, Tomás HA, Rodrigues AF, Gomes-Alves P, Bellier B, Klatzmann D, Carrondo MJT, Alves PM, Coroadinha AS.

Vaccine. 2016 Mar 18;34(13):1634-1641. doi: 10.1016/j.vaccine.2015.12.015. Epub 2016 Jan 12.

PMID:
26795367
47.

Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice.

Nehar-Belaid D, Courau T, Dérian N, Florez L, Ruocco MG, Klatzmann D.

J Immunol. 2016 Jan 15;196(2):678-90. doi: 10.4049/jimmunol.1501834. Epub 2015 Dec 7.

48.

Calpains Released by T Lymphocytes Cleave TLR2 To Control IL-17 Expression.

Perez J, Dansou B, Hervé R, Levi C, Tamouza H, Vandermeersch S, Demey-Thomas E, Haymann JP, Zafrani L, Klatzmann D, Boissier MC, Letavernier E, Baud L.

J Immunol. 2016 Jan 1;196(1):168-81. doi: 10.4049/jimmunol.1500749. Epub 2015 Nov 25.

49.

Regulatory T-cell development and function are impaired in mice lacking membrane expression of full length intercellular adhesion molecule-1.

Gottrand G, Courau T, Thomas-Vaslin V, Prevel N, Vazquez T, Ruocco MG, Lambrecht B, Bellier B, Colombo BM, Klatzmann D.

Immunology. 2015 Dec;146(4):657-70. doi: 10.1111/imm.12533. Epub 2015 Oct 28.

50.

Human and Mouse CD8(+)CD25(+)FOXP3(+) Regulatory T Cells at Steady State and during Interleukin-2 Therapy.

Churlaud G, Pitoiset F, Jebbawi F, Lorenzon R, Bellier B, Rosenzwajg M, Klatzmann D.

Front Immunol. 2015 Apr 15;6:171. doi: 10.3389/fimmu.2015.00171. eCollection 2015.

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