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Items: 24

1.

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

Vlaming H, McLean CM, Korthout T, Alemdehy MF, Hendriks S, Lancini C, Palit S, Klarenbeek S, Kwesi-Maliepaard EM, Molenaar TM, Hoekman L, Schmidlin TT, Altelaar AM, van Welsem T, Dannenberg JH, Jacobs H, van Leeuwen F.

EMBO J. 2019 Jul 15;38(14):e101564. doi: 10.15252/embj.2019101564. Epub 2019 Jun 17.

2.

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data.

Kluin RJC, Kemper K, Kuilman T, de Ruiter JR, Iyer V, Forment JV, Cornelissen-Steijger P, de Rink I, Ter Brugge P, Song JY, Klarenbeek S, McDermott U, Jonkers J, Velds A, Adams DJ, Peeper DS, Krijgsman O.

BMC Bioinformatics. 2018 Oct 4;19(1):366. doi: 10.1186/s12859-018-2353-5.

3.

Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547.

Kas SM, de Ruiter JR, Schipper K, Schut E, Bombardelli L, Wientjens E, Drenth AP, de Korte-Grimmerink R, Mahakena S, Phillips C, Smith PD, Klarenbeek S, van de Wetering K, Berns A, Wessels LFA, Jonkers J.

Cancer Res. 2018 Oct 1;78(19):5668-5679. doi: 10.1158/0008-5472.CAN-18-0757. Epub 2018 Aug 16.

4.

BRCA1-associated mammary tumorigenesis is dependent on estrogen rather than progesterone signaling.

van de Ven M, Liu X, van der Burg E, Klarenbeek S, Alexi X, Zwart W, Dijcks F, Bouwman P, Jonkers J.

J Pathol. 2018 Sep;246(1):41-53. doi: 10.1002/path.5105. Epub 2018 Jul 4.

PMID:
29877575
5.

Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma.

Kas SM, de Ruiter JR, Schipper K, Annunziato S, Schut E, Klarenbeek S, Drenth AP, van der Burg E, Klijn C, Ten Hoeve JJ, Adams DJ, Koudijs MJ, Wesseling J, Nethe M, Wessels LFA, Jonkers J.

Nat Genet. 2017 Aug;49(8):1219-1230. doi: 10.1038/ng.3905. Epub 2017 Jun 26.

PMID:
28650484
6.

Prophylactic window therapy with the clinical poly(ADP-ribose) polymerase inhibitor olaparib delays BRCA1-deficient mammary tumour formation in mice.

van de Ven M, van der Burg E, van der Gulden H, Klarenbeek S, Bouwman P, Jonkers J.

J Pathol. 2017 Mar;241(4):511-521. doi: 10.1002/path.4857. Epub 2017 Jan 23.

PMID:
27943283
7.

GATA1-Deficient Dendritic Cells Display Impaired CCL21-Dependent Migration toward Lymph Nodes Due to Reduced Levels of Polysialic Acid.

Scheenstra MR, De Cuyper IM, Branco-Madeira F, de Bleser P, Kool M, Meinders M, Hoogenboezem M, Mul E, Wolkers MC, Salerno F, Nota B, Saeys Y, Klarenbeek S, van IJcken WF, Hammad H, Philipsen S, van den Berg TK, Kuijpers TW, Lambrecht BN, Gutiérrez L.

J Immunol. 2016 Dec 1;197(11):4312-4324. Epub 2016 Nov 4.

8.

PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma.

Boelens MC, Nethe M, Klarenbeek S, de Ruiter JR, Schut E, Bonzanni N, Zeeman AL, Wientjens E, van der Burg E, Wessels L, van Amerongen R, Jonkers J.

Cell Rep. 2016 Aug 23;16(8):2087-2101. doi: 10.1016/j.celrep.2016.07.059. Epub 2016 Aug 11.

9.

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1.

Drost R, Dhillon KK, van der Gulden H, van der Heijden I, Brandsma I, Cruz C, Chondronasiou D, Castroviejo-Bermejo M, Boon U, Schut E, van der Burg E, Wientjens E, Pieterse M, Klijn C, Klarenbeek S, Loayza-Puch F, Elkon R, van Deemter L, Rottenberg S, van de Ven M, Dekkers DH, Demmers JA, van Gent DC, Agami R, Balmaña J, Serra V, Taniguchi T, Bouwman P, Jonkers J.

J Clin Invest. 2016 Aug 1;126(8):2903-18. doi: 10.1172/JCI70196. Epub 2016 Jul 25.

10.

p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice.

Tenhagen M, Klarenbeek S, Braumuller TM, Hofmann I, van der Groep P, Ter Hoeve N, van der Wall E, Jonkers J, Derksen PW.

J Mammary Gland Biol Neoplasia. 2016 Dec;21(3-4):81-88. Epub 2016 Jul 13.

11.

Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.

Annunziato S, Kas SM, Nethe M, Yücel H, Del Bravo J, Pritchard C, Bin Ali R, van Gerwen B, Siteur B, Drenth AP, Schut E, van de Ven M, Boelens MC, Klarenbeek S, Huijbers IJ, van Miltenburg MH, Jonkers J.

Genes Dev. 2016 Jun 15;30(12):1470-80. doi: 10.1101/gad.279190.116.

12.

Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation.

van Miltenburg MH, van Nimwegen MJ, Tijdens I, Lalai R, Kuiper R, Klarenbeek S, Schouten PC, de Vries A, Jonkers J, van de Water B.

Br J Cancer. 2014 May 27;110(11):2747-55. doi: 10.1038/bjc.2014.219. Epub 2014 May 8.

13.

Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling.

Schackmann RC, Klarenbeek S, Vlug EJ, Stelloo S, van Amersfoort M, Tenhagen M, Braumuller TM, Vermeulen JF, van der Groep P, Peeters T, van der Wall E, van Diest PJ, Jonkers J, Derksen PW.

Cancer Res. 2013 Aug 1;73(15):4937-49. doi: 10.1158/0008-5472.CAN-13-0180. Epub 2013 Jun 3.

14.

Genetically engineered mouse models of PI3K signaling in breast cancer.

Klarenbeek S, van Miltenburg MH, Jonkers J.

Mol Oncol. 2013 Apr;7(2):146-64. doi: 10.1016/j.molonc.2013.02.003. Epub 2013 Feb 11. Review.

15.

A preclinical mouse model of invasive lobular breast cancer metastasis.

Doornebal CW, Klarenbeek S, Braumuller TM, Klijn CN, Ciampricotti M, Hau CS, Hollmann MW, Jonkers J, de Visser KE.

Cancer Res. 2013 Jan 1;73(1):353-63. doi: 10.1158/0008-5472.CAN-11-4208. Epub 2012 Nov 14.

16.

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

Drost R, Bouwman P, Rottenberg S, Boon U, Schut E, Klarenbeek S, Klijn C, van der Heijden I, van der Gulden H, Wientjens E, Pieterse M, Catteau A, Green P, Solomon E, Morris JR, Jonkers J.

Cancer Cell. 2011 Dec 13;20(6):797-809. doi: 10.1016/j.ccr.2011.11.014.

17.

Somatic structural rearrangements in genetically engineered mouse mammary tumors.

Varela I, Klijn C, Stephens PJ, Mudie LJ, Stebbings L, Galappaththige D, van der Gulden H, Schut E, Klarenbeek S, Campbell PJ, Wessels LF, Stratton MR, Jonkers J, Futreal PA, Adams DJ.

Genome Biol. 2010;11(10):R100. doi: 10.1186/gb-2010-11-10-r100. Epub 2010 Oct 13.

18.

Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers.

Holstege H, van Beers E, Velds A, Liu X, Joosse SA, Klarenbeek S, Schut E, Kerkhoven R, Klijn CN, Wessels LF, Nederlof PM, Jonkers J.

BMC Cancer. 2010 Aug 24;10:455. doi: 10.1186/1471-2407-10-455.

19.

Expression of receptors for luteinizing hormone, gastric-inhibitory polypeptide, and vasopressin in normal adrenal glands and cortisol-secreting adrenocortical tumors in dogs.

Galac S, Kars VJ, Klarenbeek S, Teerds KJ, Mol JA, Kooistra HS.

Domest Anim Endocrinol. 2010 Jul;39(1):63-75. doi: 10.1016/j.domaniend.2010.02.003. Epub 2010 Mar 11.

PMID:
20399066
20.

Effect of growth-promoting 17beta-estradiol, 19-nortestosterone and dexamethasone on circulating levels of nine potential biomarker candidates in veal calves.

Cacciatore G, Eisenberg SW, Situ C, Mooney MH, Delahaut P, Klarenbeek S, Huet AC, Bergwerff AA, Elliott CT.

Anal Chim Acta. 2009 Apr 1;637(1-2):351-9. doi: 10.1016/j.aca.2008.11.027. Epub 2008 Nov 20.

PMID:
19286051
21.

[A dog with alveolar echinococcosis: the larval stage of the fox tapeworm].

van Riel A, Sjollema B, Klarenbeek S, van der Giessen J.

Tijdschr Diergeneeskd. 2007 Nov 1;132(21):828-31. Dutch.

PMID:
18030903
22.

Canine X-linked muscular dystrophy in a family of Grand Basset Griffon Vendéen dogs.

Klarenbeek S, Gerritzen-Bruning MJ, Rozemuller AJM, van der Lugt JJ.

J Comp Pathol. 2007 Nov;137(4):249-252. doi: 10.1016/j.jcpa.2007.06.007. Epub 2007 Sep 21.

PMID:
17888939
23.

Influence of 17beta-oestradiol, nortestosterone and dexamethasone on the adaptive immune response in veal calves.

Eisenberg SW, Cacciatore G, Klarenbeek S, Bergwerff AA, Koets AP.

Res Vet Sci. 2008 Apr;84(2):199-205. Epub 2007 Jun 22.

PMID:
17588626
24.

Reducing chloride conductance prevents hyperkalaemia-induced loss of twitch force in rat slow-twitch muscle.

van Emst MG, Klarenbeek S, Schot A, Plomp JJ, Doornenbal A, Everts ME.

J Physiol. 2004 Nov 15;561(Pt 1):169-81. Epub 2004 Sep 2.

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