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Items: 1 to 50 of 98

1.

A Nosocomial Cluster of Tigecycline- and Vancomycin-Resistant Enterococcus faecium Isolates and the Impact of rpsJ and tet(M) Mutations on Tigecycline Resistance.

Bender JK, Klare I, Fleige C, Werner G.

Microb Drug Resist. 2019 Dec 31. doi: 10.1089/mdr.2019.0346. [Epub ahead of print]

PMID:
31895641
2.

Validating a screening agar for linezolid-resistant enterococci.

Werner G, Fleige C, Klare I, Weber RE, Bender JK.

BMC Infect Dis. 2019 Dec 23;19(1):1078. doi: 10.1186/s12879-019-4711-y.

3.

Comparison of VITEK® 2, three different gradient strip tests and broth microdilution for detecting vanB-positive Enterococcus faecium isolates with low vancomycin MICs.

Klare I, Bender JK, Fleige C, Kriebel N, Hamprecht A, Gatermann S, Werner G.

J Antimicrob Chemother. 2019 Oct 1;74(10):2926-2929. doi: 10.1093/jac/dkz310.

4.

Development of a multiplex-PCR to simultaneously detect acquired linezolid resistance genes cfr, optrA and poxtA in enterococci of clinical origin.

Bender JK, Fleige C, Klare I, Werner G.

J Microbiol Methods. 2019 May;160:101-103. doi: 10.1016/j.mimet.2019.03.025. Epub 2019 Mar 30.

PMID:
30940534
6.

A Core Genome Multilocus Sequence Typing Scheme for Enterococcus faecalis.

Neumann B, Prior K, Bender JK, Harmsen D, Klare I, Fuchs S, Bethe A, Zühlke D, Göhler A, Schwarz S, Schaffer K, Riedel K, Wieler LH, Werner G.

J Clin Microbiol. 2019 Feb 27;57(3). pii: e01686-18. doi: 10.1128/JCM.01686-18. Print 2019 Mar.

7.

Reduction of nosocomial bloodstream infections and nosocomial vancomycin-resistant Enterococcus faecium on an intensive care unit after introduction of antiseptic octenidine-based bathing.

Messler S, Klare I, Wappler F, Werner G, Ligges U, Sakka SG, Mattner F.

J Hosp Infect. 2019 Mar;101(3):264-271. doi: 10.1016/j.jhin.2018.10.023. Epub 2018 Nov 5.

PMID:
30408504
8.

Rapid emergence of highly variable and transferable oxazolidinone and phenicol resistance gene optrA in German Enterococcus spp. clinical isolates.

Bender JK, Fleige C, Lange D, Klare I, Werner G.

Int J Antimicrob Agents. 2018 Dec;52(6):819-827. doi: 10.1016/j.ijantimicag.2018.09.009. Epub 2018 Sep 17.

PMID:
30236952
9.

Emergence and control of linezolid-resistant Staphylococcus epidermidis in an ICU of a German hospital.

Weßels C, Strommenger B, Klare I, Bender J, Messler S, Mattner F, Krakau M, Werner G, Layer F.

J Antimicrob Chemother. 2018 May 1;73(5):1185-1193. doi: 10.1093/jac/dky010.

PMID:
29438544
10.

Comparative evaluation of VITEK® 2 and three commercial gradient strip assays for daptomycin susceptibility testing of Staphylococcus aureus.

Weber RE, Layer F, Klare I, Werner G, Strommenger B.

J Antimicrob Chemother. 2017 Nov 1;72(11):3059-3062. doi: 10.1093/jac/dkx255.

PMID:
28961857
11.

Nursing staff fluctuation and pathogenic burden in the NICU - effective outbreak management and the underestimated relevance of non-resistant strains.

Hensel KO, van den Bruck R, Klare I, Heldmann M, Ghebremedhin B, Jenke AC.

Sci Rep. 2017 Mar 21;7:45014. doi: 10.1038/srep45014.

12.

Detection of a cfr(B) Variant in German Enterococcus faecium Clinical Isolates and the Impact on Linezolid Resistance in Enterococcus spp.

Bender JK, Fleige C, Klare I, Fiedler S, Mischnik A, Mutters NT, Dingle KE, Werner G.

PLoS One. 2016 Nov 28;11(11):e0167042. doi: 10.1371/journal.pone.0167042. eCollection 2016.

13.

Emergence of linezolid- and vancomycin-resistant Enterococcus faecium in a department for hematologic stem cell transplantation.

Krull M, Klare I, Ross B, Trenschel R, Beelen DW, Todt D, Steinmann E, Buer J, Rath PM, Steinmann J.

Antimicrob Resist Infect Control. 2016 Sep 22;5:31. doi: 10.1186/s13756-016-0131-6. eCollection 2016.

14.

Does antibiotic resistance impair plasma susceptibility of multi-drug resistant clinical isolates of enterococci in vitro?

Napp M, von Podewils S, Klare I, Haase H, Kasch R, Gümbel D, Ekkernkamp A, Jünger M, Daeschlein G.

Gut Pathog. 2016 Sep 1;8(1):41. doi: 10.1186/s13099-016-0122-4. eCollection 2016.

15.

Population structure and acquisition of the vanB resistance determinant in German clinical isolates of Enterococcus faecium ST192.

Bender JK, Kalmbach A, Fleige C, Klare I, Fuchs S, Werner G.

Sci Rep. 2016 Feb 23;6:21847. doi: 10.1038/srep21847.

16.

Tigecycline resistance in clinical isolates of Enterococcus faecium is mediated by an upregulation of plasmid-encoded tetracycline determinants tet(L) and tet(M).

Fiedler S, Bender JK, Klare I, Halbedel S, Grohmann E, Szewzyk U, Werner G.

J Antimicrob Chemother. 2016 Apr;71(4):871-81. doi: 10.1093/jac/dkv420. Epub 2015 Dec 18.

PMID:
26682961
17.

Complete Genome Sequence of the Gut Commensal and Laboratory Strain Enterococcus faecium 64/3.

Bender JK, Fiedler S, Klare I, Werner G.

Genome Announc. 2015 Nov 19;3(6). pii: e01275-15. doi: 10.1128/genomeA.01275-15.

18.

Evaluation of DiversiLab®, MLST and PFGE typing for discriminating clinical Enterococcus faecium isolates.

Werner G, Fleige C, Neumann B, Bender JK, Layer F, Klare I.

J Microbiol Methods. 2015 Nov;118:81-4. doi: 10.1016/j.mimet.2015.08.019. Epub 2015 Sep 1.

PMID:
26341611
19.

Epidemiology and molecular typing of VRE bloodstream isolates in an Irish tertiary care hospital.

Ryan L, O'Mahony E, Wrenn C, FitzGerald S, Fox U, Boyle B, Schaffer K, Werner G, Klare I.

J Antimicrob Chemother. 2015 Oct;70(10):2718-24. doi: 10.1093/jac/dkv185. Epub 2015 Jul 4.

PMID:
26142479
20.

Increased frequency of linezolid resistance among clinical Enterococcus faecium isolates from German hospital patients.

Klare I, Fleige C, Geringer U, Thürmer A, Bender J, Mutters NT, Mischnik A, Werner G.

J Glob Antimicrob Resist. 2015 Jun;3(2):128-131. doi: 10.1016/j.jgar.2015.02.007. Epub 2015 Apr 13.

PMID:
27873661
21.

Pre-Use Susceptibility to Ceftaroline in Clinical Staphylococcus aureus Isolates from Germany: Is There a Non-Susceptible Pool to be Selected?

Strommenger B, Layer F, Klare I, Werner G.

PLoS One. 2015 May 8;10(5):e0125864. doi: 10.1371/journal.pone.0125864. eCollection 2015.

22.

[Vancomycin-resistant enterococci (VRE). Recent results and trends in development of antibiotic resistance].

Klare I, Witte W, Wendt C, Werner G.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012 Nov;55(11-12):1387-400. doi: 10.1007/s00103-012-1564-6. German.

PMID:
23114437
23.

Vancomycin-resistant vanB-type Enterococcus faecium isolates expressing varying levels of vancomycin resistance and being highly prevalent among neonatal patients in a single ICU.

Werner G, Klare I, Fleige C, Geringer U, Witte W, Just HM, Ziegler R.

Antimicrob Resist Infect Control. 2012 May 30;1(1):21. doi: 10.1186/2047-2994-1-21.

24.

Performance of three chromogenic VRE screening agars, two Etest(®) vancomycin protocols, and different microdilution methods in detecting vanB genotype Enterococcus faecium with varying vancomycin MICs.

Klare I, Fleige C, Geringer U, Witte W, Werner G.

Diagn Microbiol Infect Dis. 2012 Oct;74(2):171-6. doi: 10.1016/j.diagmicrobio.2012.06.020. Epub 2012 Aug 15.

PMID:
22901792
25.

Cross-transmission rates of enterococcal isolates among newborns in a neonatal intensive care unit.

Böhme H, Königsmark C, Klare I, Zischka M, Werner G.

Pediatr Rep. 2012 Jan 2;4(1):e15. doi: 10.4081/pr.2012.e15. Epub 2012 Mar 26.

26.

Insight into antimicrobial susceptibility and population structure of contemporary human Enterococcus faecalis isolates from Europe.

Kuch A, Willems RJ, Werner G, Coque TM, Hammerum AM, Sundsfjord A, Klare I, Ruiz-Garbajosa P, Simonsen GS, van Luit-Asbroek M, Hryniewicz W, Sadowy E.

J Antimicrob Chemother. 2012 Mar;67(3):551-8. doi: 10.1093/jac/dkr544. Epub 2011 Dec 29.

PMID:
22207599
27.

Comparison of direct cultivation on a selective solid medium, polymerase chain reaction from an enrichment broth, and the BD GeneOhm™ VanR Assay for identification of vancomycin-resistant enterococci in screening specimens.

Werner G, Serr A, Schütt S, Schneider C, Klare I, Witte W, Wendt C.

Diagn Microbiol Infect Dis. 2011 Aug;70(4):512-21. doi: 10.1016/j.diagmicrobio.2011.04.004.

PMID:
21767707
28.

IS element IS16 as a molecular screening tool to identify hospital-associated strains of Enterococcus faecium.

Werner G, Fleige C, Geringer U, van Schaik W, Klare I, Witte W.

BMC Infect Dis. 2011 Mar 31;11:80. doi: 10.1186/1471-2334-11-80.

29.

Tolerance and safety of the potentially probiotic strain Lactobacillus rhamnosus PRSF-L477: a randomised, double-blind placebo-controlled trial in healthy volunteers.

Wind RD, Tolboom H, Klare I, Huys G, Knol J.

Br J Nutr. 2010 Dec;104(12):1806-16. doi: 10.1017/S0007114510002746. Epub 2010 Aug 9.

PMID:
20691131
30.

High-level ciprofloxacin resistance among hospital-adapted Enterococcus faecium (CC17).

Werner G, Fleige C, Ewert B, Laverde-Gomez JA, Klare I, Witte W.

Int J Antimicrob Agents. 2010 Feb;35(2):119-25. doi: 10.1016/j.ijantimicag.2009.10.012. Epub 2009 Dec 16.

PMID:
20006472
31.

Is there an association between nosocomial infection rates and bacterial cross transmissions?

Kola A, Schwab F, Bärwolff S, Eckmanns T, Weist K, Dinger E, Klare I, Witte W, Ruden H, Gastmeier P.

Crit Care Med. 2010 Jan;38(1):46-50. doi: 10.1097/CCM.0b013e3181b42a9b.

PMID:
19770743
32.

Emergence and spread of vancomycin resistance among enterococci in Europe.

Werner G, Coque TM, Hammerum AM, Hope R, Hryniewicz W, Johnson A, Klare I, Kristinsson KG, Leclercq R, Lester CH, Lillie M, Novais C, Olsson-Liljequist B, Peixe LV, Sadowy E, Simonsen GS, Top J, Vuopio-Varkila J, Willems RJ, Witte W, Woodford N.

Euro Surveill. 2008 Nov 20;13(47). pii: 19046. Review.

33.

Genotypic diversity, antimicrobial resistance, and virulence factors of human isolates and probiotic cultures constituting two intraspecific groups of Enterococcus faecium isolates.

Vankerckhoven V, Huys G, Vancanneyt M, Snauwaert C, Swings J, Klare I, Witte W, Van Autgaerden T, Chapelle S, Lammens C, Goossens H.

Appl Environ Microbiol. 2008 Jul;74(14):4247-55. doi: 10.1128/AEM.02474-07. Epub 2008 May 16.

34.

Emergence and spread of antibiotic-resistant Gram-positive bacterial pathogens.

Witte W, Cuny C, Klare I, Nübel U, Strommenger B, Werner G.

Int J Med Microbiol. 2008 Jul;298(5-6):365-77. doi: 10.1016/j.ijmm.2007.10.005. Epub 2008 Mar 5. Review.

PMID:
18325835
35.

Tigecycline-resistant Enterococcus faecalis strain isolated from a German intensive care unit patient.

Werner G, Gfrörer S, Fleige C, Witte W, Klare I.

J Antimicrob Chemother. 2008 May;61(5):1182-3. doi: 10.1093/jac/dkn065. Epub 2008 Feb 18. No abstract available.

PMID:
18285315
37.

Discrimination between epidemic and non-epidemic glycopeptide-resistant E. faecium in a post-outbreak situation.

Borgmann S, Schulte B, Wolz C, Gruber H, Werner G, Goerke C, Klare I, Beyser K, Heeg P, Autenrieth IB.

J Hosp Infect. 2007 Sep;67(1):49-55. Epub 2007 Jul 31.

PMID:
17669548
38.

Detection of mutations conferring resistance to linezolid in Enterococcus spp. by fluorescence in situ hybridization.

Werner G, Bartel M, Wellinghausen N, Essig A, Klare I, Witte W, Poppert S.

J Clin Microbiol. 2007 Oct;45(10):3421-3. Epub 2007 May 2.

40.

Antimicrobial susceptibilities of Lactobacillus, Pediococcus and Lactococcus human isolates and cultures intended for probiotic or nutritional use.

Klare I, Konstabel C, Werner G, Huys G, Vankerckhoven V, Kahlmeter G, Hildebrandt B, Müller-Bertling S, Witte W, Goossens H.

J Antimicrob Chemother. 2007 May;59(5):900-12. Epub 2007 Mar 16.

PMID:
17369278
41.

[Prevention and control of the spread of vancomycin-resistant enterococci: results of a workshop held by the German Society for Hygiene and Microbiology].

Vonberg RP, Chaberny IF, Kola A, Mattner F, Borgmann S, Dettenkofer M, Jonas D, Fahr AM, Klare I, Werner G, Weist K, Wendt C, Gastmeier P; German Society for Hygiene and Microbiology.

Anaesthesist. 2007 Feb;56(2):151-7. German.

PMID:
17171367
42.

Molecular epidemiology of hospital-acquired vancomycin-resistant enterococci.

Abele-Horn M, Vogel U, Klare I, Konstabel C, Trabold R, Kurihara R, Witte W, Kreth W, Schlegel PG, Claus H.

J Clin Microbiol. 2006 Nov;44(11):4009-13. Epub 2006 Sep 27.

43.

Rapid emergence of resistance to linezolid during linezolid therapy of an Enterococcus faecium infection.

Seedat J, Zick G, Klare I, Konstabel C, Weiler N, Sahly H.

Antimicrob Agents Chemother. 2006 Dec;50(12):4217-9. Epub 2006 Sep 18.

44.

Spread of ampicillin/vancomycin-resistant Enterococcus faecium of the epidemic-virulent clonal complex-17 carrying the genes esp and hyl in German hospitals.

Klare I, Konstabel C, Mueller-Bertling S, Werner G, Strommenger B, Kettlitz C, Borgmann S, Schulte B, Jonas D, Serr A, Fahr AM, Eigner U, Witte W.

Eur J Clin Microbiol Infect Dis. 2005 Dec;24(12):815-25. Review.

PMID:
16374593
45.

Evaluation of new broth media for microdilution antibiotic susceptibility testing of Lactobacilli, Pediococci, Lactococci, and Bifidobacteria.

Klare I, Konstabel C, Müller-Bertling S, Reissbrodt R, Huys G, Vancanneyt M, Swings J, Goossens H, Witte W.

Appl Environ Microbiol. 2005 Dec;71(12):8982-6.

46.

Linezolid-resistant E. faecium isolated from an open joint fracture: a report of the first isolate from Italy?

Schulte B, Klare I, Strommenger B, Werner G, Autenrieth IB, Bahrs C, Heeg P, Borgmann S.

Int J Hyg Environ Health. 2005;208(6):477-80. Epub 2005 Aug 11.

PMID:
16325557
47.

How many infections are caused by patient-to-patient transmission in intensive care units?

Grundmann H, Bärwolff S, Tami A, Behnke M, Schwab F, Geffers C, Halle E, Göbel UB, Schiller R, Jonas D, Klare I, Weist K, Witte W, Beck-Beilecke K, Schumacher M, Rüden H, Gastmeier P.

Crit Care Med. 2005 May;33(5):946-51.

PMID:
15891318
48.

Outbreak of vancomycin-resistant enterococci (VRE) in a hematological oncology ward and hygienic preventive measures. A long-term study.

Knoll M, Daeschlein G, Okpara-Hofmann J, Klare I, Wilhelms D, Wolf HH, Borneff-Lipp M.

Onkologie. 2005 Apr;28(4):187-92. Epub 2005 Mar 31.

PMID:
15840966
49.

[Incidence of transmission of pathogens in intensive care units. Results of the SIR 3 study].

Bärwolff S, Grundmann H, Schwab F, Tami A, Behnke M, Geffers C, Halle E, Göbel U, Schiller R, Jonas D, Klare I, Weist K, Witte W, Dinger E, Beilecke K, Rüden H, Gastmeier P.

Anaesthesist. 2005 Jun;54(6):560-6. German.

PMID:
15809853
50.

Occurrence of antibiotic-resistant enterobacteria in agricultural foodstuffs.

Boehme S, Werner G, Klare I, Reissbrodt R, Witte W.

Mol Nutr Food Res. 2004 Dec;48(7):522-31.

PMID:
15538714

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