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Items: 40

1.

Pluripotent stem cell-derived bile canaliculi-forming hepatocytes to study genetic liver diseases involving hepatocyte polarity.

Overeem AW, Klappe K, Parisi S, Klöters-Planchy P, Mataković L, du Teil Espina M, Drouin CA, Weiss KH, van IJzendoorn SCD.

J Hepatol. 2019 Aug;71(2):344-356. doi: 10.1016/j.jhep.2019.03.031. Epub 2019 Apr 6.

PMID:
30965071
2.

GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis.

Qin J, Sikkema AH, van der Bij K, de Jonge JC, Klappe K, Nies V, Jonker JW, Kok JW, Hoekstra D, Baron W.

J Neurosci. 2017 Oct 11;37(41):9925-9938. doi: 10.1523/JNEUROSCI.0103-17.2017. Epub 2017 Sep 12.

3.

Vaginal epithelial cells regulate membrane adhesiveness to co-ordinate bacterial adhesion.

Younes JA, Klappe K, Kok JW, Busscher HJ, Reid G, van der Mei HC.

Cell Microbiol. 2016 Apr;18(4):605-14. doi: 10.1111/cmi.12537. Epub 2015 Nov 4.

PMID:
26477544
4.

Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis.

Karimian G, Buist-Homan M, Schmidt M, Tietge UJ, de Boer JF, Klappe K, Kok JW, Combettes L, Tordjmann T, Faber KN, Moshage H.

Biochim Biophys Acta. 2013 Dec;1832(12):1922-9. doi: 10.1016/j.bbadis.2013.06.011. Epub 2013 Jun 28.

5.

Separation of actin-dependent and actin-independent lipid rafts.

Klappe K, Hummel I, Kok JW.

Anal Biochem. 2013 Jul 15;438(2):133-5. doi: 10.1016/j.ab.2013.03.018. Epub 2013 Mar 26.

PMID:
23541521
6.

Long term myriocin treatment increases MRP1 transport activity.

Meszaros P, Klappe K, van Dam A, Ivanova PT, Milne SB, Myers DS, Brown HA, Permentier H, Hoekstra D, Kok JW.

Int J Biochem Cell Biol. 2013 Feb;45(2):326-34. doi: 10.1016/j.biocel.2012.11.009. Epub 2012 Nov 23.

7.

The function of the ATP-binding cassette (ABC) transporter ABCB1 is not susceptible to actin disruption.

Meszaros P, Hummel I, Klappe K, Draghiciu O, Hoekstra D, Kok JW.

Biochim Biophys Acta. 2013 Feb;1828(2):340-51. doi: 10.1016/j.bbamem.2012.10.007. Epub 2012 Oct 17.

8.

Function of MRP1/ABCC1 is not dependent on cholesterol or cholesterol-stabilized lipid rafts.

Meszaros P, Klappe K, Hummel I, Hoekstra D, Kok JW.

Biochem J. 2011 Aug 1;437(3):483-91. doi: 10.1042/BJ20110427.

PMID:
21609321
9.

Multidrug resistance-related protein 1 (MRP1) function and localization depend on cortical actin.

Hummel I, Klappe K, Ercan C, Kok JW.

Mol Pharmacol. 2011 Feb;79(2):229-40. doi: 10.1124/mol.110.069013. Epub 2010 Nov 2.

PMID:
21045108
10.

Extensive sphingolipid depletion does not affect lipid raft integrity or lipid raft localization and efflux function of the ABC transporter MRP1.

Klappe K, Dijkhuis AJ, Hummel I, van Dam A, Ivanova PT, Milne SB, Myers DS, Brown HA, Permentier H, Kok JW.

Biochem J. 2010 Sep 15;430(3):519-29. doi: 10.1042/BJ20091882.

11.

Lipid dependence of ABC transporter localization and function.

Klappe K, Hummel I, Hoekstra D, Kok JW.

Chem Phys Lipids. 2009 Oct;161(2):57-64. doi: 10.1016/j.chemphyslip.2009.07.004. Epub 2009 Aug 3. Review.

PMID:
19651114
12.

Gangliosides do not affect ABC transporter function in human neuroblastoma cells.

Dijkhuis AJ, Klappe K, Kamps W, Sietsma H, Kok JW.

J Lipid Res. 2006 Jun;47(6):1187-95. Epub 2006 Mar 18.

13.

PDMP sensitizes neuroblastoma to paclitaxel by inducing aberrant cell cycle progression leading to hyperploidy.

Dijkhuis AJ, Klappe K, Jacobs S, Kroesen BJ, Kamps W, Sietsma H, Kok JW.

Mol Cancer Ther. 2006 Mar;5(3):593-601.

14.

Drug resistance-associated changes in sphingolipids and ABC transporters occur in different regions of membrane domains.

Hinrichs JW, Klappe K, van Riezen M, Kok JW.

J Lipid Res. 2005 Nov;46(11):2367-76. Epub 2005 Sep 8.

15.

Rafts as missing link between multidrug resistance and sphingolipid metabolism.

Hinrichs JW, Klappe K, Kok JW.

J Membr Biol. 2005 Jan;203(2):57-64. Review. No abstract available.

PMID:
15981711
16.

Up-regulation of lactosylceramide synthase in MDR1 overexpressing human liver tumour cells.

Hummel I, Klappe K, Kok JW.

FEBS Lett. 2005 Jun 20;579(16):3381-4.

17.
18.
19.

The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs.

Veldman RJ, Mita A, Cuvillier O, Garcia V, Klappe K, Medin JA, Campbell JD, Carpentier S, Kok JW, Levade T.

FASEB J. 2003 Jun;17(9):1144-6. Epub 2003 Apr 8.

PMID:
12692077
20.

Altered sphingolipid metabolism in multidrug-resistant ovarian cancer cells is due to uncoupling of glycolipid biosynthesis in the Golgi apparatus.

Veldman RJ, Klappe K, Hinrichs J, Hummel I, van der Schaaf G, Sietsma H, Kok JW.

FASEB J. 2002 Jul;16(9):1111-3. Epub 2002 May 8.

PMID:
12039850
21.

Differential expression of sphingolipids in MRP1 overexpressing HT29 cells.

Kok JW, Veldman RJ, Klappe K, Koning H, Filipeanu CM, Müller M.

Int J Cancer. 2000 Jul 15;87(2):172-8.

22.

Inhibition of P-glycoprotein activity and chemosensitization of multidrug-resistant ovarian carcinoma 2780AD cells by hexanoylglucosylceramide.

Veldman RJ, Sietsma H, Klappe K, Hoekstra D, Kok JW.

Biochem Biophys Res Commun. 1999 Dec 20;266(2):492-6.

PMID:
10600530
23.

Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated.

Kok JW, Babia T, Klappe K, Egea G, Hoekstra D.

Biochem J. 1998 Aug 1;333 ( Pt 3):779-86.

24.
25.

Interferon-gamma-induced differentiation and apoptosis of HT29 cells: dissociation of (glucosyl)ceramide signaling.

Veldman RJ, Klappe K, Hoekstra D, Kok JW.

Biochem Biophys Res Commun. 1998 Jun 29;247(3):802-8.

PMID:
9647774
26.

Metabolism and apoptotic properties of elevated ceramide in HT29rev cells.

Veldman RJ, Klappe K, Hoekstra D, Kok JW.

Biochem J. 1998 Apr 15;331 ( Pt 2):563-9.

27.

Dihydroceramide biology. Structure-specific metabolism and intracellular localization.

Kok JW, Nikolova-Karakashian M, Klappe K, Alexander C, Merrill AH Jr.

J Biol Chem. 1997 Aug 22;272(34):21128-36.

29.

Interaction of annexins with membranes: the N-terminus as a governing parameter as revealed with a chimeric annexin.

Hoekstra D, Buist-Arkema R, Klappe K, Reutelingsperger CP.

Biochemistry. 1993 Dec 28;32(51):14194-202.

PMID:
8260506
30.

Fluorescence assays to monitor fusion of enveloped viruses.

Hoekstra D, Klappe K.

Methods Enzymol. 1993;220:261-76. No abstract available.

PMID:
8394492
31.

Fusion of Sendai virus with human HL-60 and CEM cells: different kinetics of fusion for two isolates.

Pedroso de Lima MC, Nir S, Flasher D, Klappe K, Hoekstra D, Düzgüneş N.

Biochim Biophys Acta. 1991 Dec 9;1070(2):446-54.

PMID:
1662538
33.

Mass action analysis of kinetics and extent of fusion between Sendai virus and phospholipid vesicles.

Nir S, Klappe K, Hoekstra D.

Biochemistry. 1986 Dec 16;25(25):8261-6.

PMID:
3028475
34.

Parameters affecting fusion between Sendai virus and liposomes. Role of viral proteins, liposome composition, and pH.

Klappe K, Wilschut J, Nir S, Hoekstra D.

Biochemistry. 1986 Dec 16;25(25):8252-60.

PMID:
3028474
35.
36.
38.

Characterization of the fusogenic properties of Sendai virus: kinetics of fusion with erythrocyte membranes.

Hoekstra D, Klappe K, de Boer T, Wilschut J.

Biochemistry. 1985 Aug 27;24(18):4739-45.

PMID:
3000417
39.

Fluorescence method for measuring the kinetics of fusion between biological membranes.

Hoekstra D, de Boer T, Klappe K, Wilschut J.

Biochemistry. 1984 Nov 20;23(24):5675-81.

PMID:
6098295
40.

lac Repressor headpiece binds specifically to half of the lac operator: a proton nuclear magnetic resonance study.

Scheek RM, Zuiderweg ER, Klappe KJ, van Boom JH, Kaptein R, Rüterjans H, Beyreuther K.

Biochemistry. 1983 Jan 4;22(1):228-35.

PMID:
6338916

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