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Items: 20


Prognostic Impact of Natural Killer Cell Count in Follicular Lymphoma and Diffuse Large B-cell Lymphoma Patients Treated with Immunochemotherapy.

Klanova M, Oestergaard MZ, Trněný M, Hiddemann W, Marcus R, Sehn LH, Vitolo U, Bazeos A, Goede V, Zeuner H, Knapp A, Sahin D, Spielewoy N, Bolen CR, Cardona A, Klein C, Venstrom JM, Nielsen T, Fingerle-Rowson G.

Clin Cancer Res. 2019 Aug 1;25(15):4634-4643. doi: 10.1158/1078-0432.CCR-18-3270. Epub 2019 May 3.


Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.

Prukova D, Andera L, Nahacka Z, Karolova J, Svaton M, Klanova M, Havranek O, Soukup J, Svobodova K, Zemanova Z, Tuskova D, Pokorna E, Helman K, Forsterova K, Pacheco-Blanco M, Vockova P, Berkova A, Fronkova E, Trneny M, Klener P.

Clin Cancer Res. 2019 Jul 15;25(14):4455-4465. doi: 10.1158/1078-0432.CCR-18-3275. Epub 2019 Apr 19.


Integration of cell of origin into the clinical CNS International Prognostic Index improves CNS relapse prediction in DLBCL.

Klanova M, Sehn LH, Bence-Bruckler I, Cavallo F, Jin J, Martelli M, Stewart D, Vitolo U, Zaja F, Zhang Q, Mattiello F, Sellam G, Punnoose EA, Szafer-Glusman E, Bolen CR, Oestergaard MZ, Fingerle-Rowson GR, Nielsen T, Trneny M.

Blood. 2019 Feb 28;133(9):919-926. doi: 10.1182/blood-2018-07-862862. Epub 2019 Jan 7.


Immunochemotherapy With Obinutuzumab or Rituximab for Previously Untreated Follicular Lymphoma in the GALLIUM Study: Influence of Chemotherapy on Efficacy and Safety.

Hiddemann W, Barbui AM, Canales MA, Cannell PK, Collins GP, Dürig J, Forstpointner R, Herold M, Hertzberg M, Klanova M, Radford J, Seymour JF, Tobinai K, Trotman J, Burciu A, Fingerle-Rowson G, Wolbers M, Nielsen T, Marcus RE.

J Clin Oncol. 2018 Aug 10;36(23):2395-2404. doi: 10.1200/JCO.2017.76.8960. Epub 2018 Jun 1.


Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement.

Maswabi BC, Molinsky J, Savvulidi F, Zikmund T, Prukova D, Tuskova D, Klanova M, Vockova P, Lateckova L, Sefc L, Zivny J, Trneny M, Klener P.

Haematologica. 2017 Apr;102(4):e152-e155. doi: 10.3324/haematol.2016.151571. Epub 2017 Jan 5. No abstract available.


Single-agent cytarabine is insufficient for the treatment of human mantle cell lymphoma in mouse xenograft model.

Klanova M, Soukup T, Molinsky J, Lateckova L, Vockova P, Alam M, Zivny J, Trneny M, Klener P.

Neoplasma. 2016;63(5):774-8. doi: 10.4149/neo_2016_515.


Significantly higher numbers of proB cells in healthy Caucasians compared to Asians: Is there association with incidence of CLL?

Molinsky J, Maswabi B, Prukova D, Klanova M, Vockova P, Zikmund T, Savvulidi F, Alam M, Sefc L, Vokurka M, Obrtlikova P, Trneny M, Klener P Jr.

Blood Cells Mol Dis. 2016 Mar;57:118-9. doi: 10.1016/j.bcmd.2015.12.001. Epub 2015 Dec 2. No abstract available.


Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma.

Klanova M, Andera L, Brazina J, Svadlenka J, Benesova S, Soukup J, Prukova D, Vejmelkova D, Jaksa R, Helman K, Vockova P, Lateckova L, Molinsky J, Maswabi BC, Alam M, Kodet R, Pytlik R, Trneny M, Klener P.

Clin Cancer Res. 2016 Mar 1;22(5):1138-49. doi: 10.1158/1078-0432.CCR-15-1191. Epub 2015 Oct 14. Erratum in: Clin Cancer Res. 2016 Aug 1;22(15):3984.


Detailed Functional and Proteomic Characterization of Fludarabine Resistance in Mantle Cell Lymphoma Cells.

Lorkova L, Scigelova M, Arrey TN, Vit O, Pospisilova J, Doktorova E, Klanova M, Alam M, Vockova P, Maswabi B, Klener P Jr, Petrak J.

PLoS One. 2015 Aug 18;10(8):e0135314. doi: 10.1371/journal.pone.0135314. eCollection 2015.


Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents.

Klanova M, Lorkova L, Vit O, Maswabi B, Molinsky J, Pospisilova J, Vockova P, Mavis C, Lateckova L, Kulvait V, Vejmelkova D, Jaksa R, Hernandez F, Trneny M, Vokurka M, Petrak J, Klener P Jr.

Mol Cancer. 2014 Jun 27;13:159. doi: 10.1186/1476-4598-13-159.


Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research.

Klanova M, Soukup T, Jaksa R, Molinsky J, Lateckova L, Maswabi BC, Prukova D, Brezinova J, Michalova K, Vockova P, Hernandez-Ilizaliturri F, Kulvait V, Zivny J, Vokurka M, Necas E, Trneny M, Klener P.

Lab Invest. 2014 Jul;94(7):806-17. doi: 10.1038/labinvest.2014.61. Epub 2014 May 26.


[Multiple myeloma].

Špička I, Klánová M.

Vnitr Lek. 2013 Jul;59(7):627-30. Review. Czech.


In vivo growth of mantle cell lymphoma xenografts in immunodeficient mice is positively regulated by VEGF and associated with significant up-regulation of CD31/PECAM1.

Molinský J, Klánová M, Maswabi B, Soukup T, Trněný M, Nečas E, Živný J, Klener P.

Folia Biol (Praha). 2013;59(1):26-31.


Resistance to TRAIL in mantle cell lymphoma cells is associated with the decreased expression of purine metabolism enzymes.

Pospisilova J, Vit O, Lorkova L, Klanova M, Zivny J, Klener P, Petrak J.

Int J Mol Med. 2013 May;31(5):1273-9. doi: 10.3892/ijmm.2013.1302. Epub 2013 Mar 13.


The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms.

Beranova L, Pombinho AR, Spegarova J, Koc M, Klanova M, Molinsky J, Klener P, Bartunek P, Andera L.

Apoptosis. 2013 Jun;18(6):739-50. doi: 10.1007/s10495-013-0823-9.


Multi-level disruption of the extrinsic apoptotic pathway mediates resistance of leukemia cells to TNF-related apoptosis-inducing ligand (TRAIL).

Leahomschi S, Molinsky J, Klanova M, Andera L, Peterka M, Gasova Z, Klener P Sr, Trneny M, Necas E, Simonova T, Zivny J, Klener P Jr.

Neoplasma. 2013;60(2):223-31.


Roscovitine sensitizes leukemia and lymphoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

Molinsky J, Klanova M, Koc M, Beranova L, Andera L, Ludvikova Z, Bohmova M, Gasova Z, Strnad M, Ivanek R, Trneny M, Necas E, Zivny J, Klener P.

Leuk Lymphoma. 2013 Feb;54(2):372-80. doi: 10.3109/10428194.2012.710331. Epub 2012 Sep 8.


Intrapleural bortezomib for the therapy of myelomatous pleural effusion: a case report.

Klanova M, Klener P, Trneny M, Straub J, Spicka I.

Case Reports Immunol. 2012;2012:978479. doi: 10.1155/2012/978479. Epub 2012 Oct 11.


Pharmacokinetics and pharmacodynamics of cetirizine in infants and toddlers.

Spicák V, Dab I, Hulhoven R, Desager JP, Klánová M, de Longueville M, Harvengt C.

Clin Pharmacol Ther. 1997 Mar;61(3):325-30.


[Case report of the clinico-biochemical diagnosis of the peroxisomal disease syndrome of Zellweger].

Klánová M, Kozich V, Pehal F.

Cesk Pediatr. 1990 Jan;45(1):50-1. Czech. No abstract available.


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