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Items: 42

1.

Peptide-Functionalized Hydrogel Cubes for Active Tumor Cell Targeting.

Xue B, Kozlovskaya V, Sherwani MA, Ratnayaka S, Habib S, Anderson T, Manuvakhova M, Klampfer L, Yusuf N, Kharlampieva E.

Biomacromolecules. 2018 Oct 8;19(10):4084-4097. doi: 10.1021/acs.biomac.8b01088. Epub 2018 Sep 12.

PMID:
30169033
2.

Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation.

Owusu BY, Thomas S, Venukadasula P, Han Z, Janetka JW, Galemmo RA Jr, Klampfer L.

Oncotarget. 2017 May 29;8(38):63014-63025. doi: 10.18632/oncotarget.18260. eCollection 2017 Sep 8.

3.

Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment.

Owusu BY, Galemmo R, Janetka J, Klampfer L.

Cancers (Basel). 2017 Apr 17;9(4). pii: E35. doi: 10.3390/cancers9040035. Review.

4.

Modulation of STAT1-Driven Transcriptional Activity by Histone Deacetylases.

Owusu BY, Klampfer L.

Methods Mol Biol. 2017;1510:277-285.

PMID:
27761828
5.

Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling.

Owusu BY, Bansal N, Venukadasula PK, Ross LJ, Messick TE, Goel S, Galemmo RA, Klampfer L.

Oncotarget. 2016 May 17;7(20):29492-506. doi: 10.18632/oncotarget.8785.

6.

Design and Synthesis of Nonpeptide Inhibitors of Hepatocyte Growth Factor Activation.

Venukadasula PK, Owusu BY, Bansal N, Ross LJ, Hobrath JV, Bao D, Truss JW, Stackhouse M, Messick TE, Klampfer L, Galemmo RA Jr.

ACS Med Chem Lett. 2015 Dec 22;7(2):177-81. doi: 10.1021/acsmedchemlett.5b00357. eCollection 2016 Feb 11.

7.

α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer.

Han Z, Harris PK, Karmakar P, Kim T, Owusu BY, Wildman SA, Klampfer L, Janetka JW.

ChemMedChem. 2016 Mar 17;11(6):585-99. doi: 10.1002/cmdc.201500600. Epub 2016 Feb 17.

PMID:
26889658
8.

Prognostic and Predictive Significance of Stromal Fibroblasts and Macrophages in Colon Cancer.

Owusu BY, Vaid M, Kaler P, Klampfer L.

Biomark Cancer. 2015 Nov 2;7(Suppl 1):29-37. doi: 10.4137/BIC.S25247. eCollection 2015. Review.

9.

Vitamin D and colon cancer.

Klampfer L.

World J Gastrointest Oncol. 2014 Nov 15;6(11):430-7. doi: 10.4251/wjgo.v6.i11.430. Review.

10.

The Role of STAT1 for Crosstalk between Fibroblasts and Colon Cancer Cells.

Kaler P, Owusu BY, Augenlicht L, Klampfer L.

Front Oncol. 2014 Apr 30;4:88. doi: 10.3389/fonc.2014.00088. eCollection 2014.

11.

Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan.

Maitra R, Seetharam R, Tesfa L, Augustine TA, Klampfer L, Coffey MC, Mariadason JM, Goel S.

Oncotarget. 2014 May 15;5(9):2807-19.

12.

K-Ras, intestinal homeostasis and colon cancer.

Goel S, Huang J, Klampfer L.

Curr Clin Pharmacol. 2015;10(1):73-81. Review.

PMID:
24219000
13.

Activating mutations in β-catenin in colon cancer cells alter their interaction with macrophages; the role of snail.

Kaler P, Augenlicht L, Klampfer L.

PLoS One. 2012;7(9):e45462. doi: 10.1371/journal.pone.0045462. Epub 2012 Sep 21.

14.

Cytokines, inflammation and colon cancer.

Klampfer L.

Curr Cancer Drug Targets. 2011 May;11(4):451-64. Review.

15.

Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1beta-dependent stabilization of Snail in tumor cells.

Kaler P, Galea V, Augenlicht L, Klampfer L.

PLoS One. 2010 Jul 22;5(7):e11700. doi: 10.1371/journal.pone.0011700.

16.

The NF-κB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1β.

Kaler P, Godasi BN, Augenlicht L, Klampfer L.

Cancer Microenviron. 2009 Sep 25;2(1):69-80. doi: 10.1007/s12307-009-0030-y. eCollection 2009 Dec.

17.

Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3.

Kaler P, Augenlicht L, Klampfer L.

Oncogene. 2009 Nov 5;28(44):3892-902. doi: 10.1038/onc.2009.247. Epub 2009 Aug 24.

18.

Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis: the role of p53 and p21.

Escandell JM, Kaler P, Recio MC, Sasazuki T, Shirasawa S, Augenlicht L, Ríos JL, Klampfer L.

Biochem Pharmacol. 2008 Jul 15;76(2):198-207. doi: 10.1016/j.bcp.2008.05.004. Epub 2008 May 8.

19.

PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab.

Jhawer M, Goel S, Wilson AJ, Montagna C, Ling YH, Byun DS, Nasser S, Arango D, Shin J, Klampfer L, Augenlicht LH, Perez-Soler R, Mariadason JM.

Cancer Res. 2008 Mar 15;68(6):1953-61. doi: 10.1158/0008-5472.CAN-07-5659. Erratum in: Cancer Res. 2008 Aug 15;68(16):6859. Soler, Roman Perez [corrected to Perez-Soler, Roman]. Cancer Res. 2009 Dec 1;69(23):9156.

20.

HDAC2 deficiency sensitizes colon cancer cells to TNFalpha-induced apoptosis through inhibition of NF-kappaB activity.

Kaler P, Sasazuki T, Shirasawa S, Augenlicht L, Klampfer L.

Exp Cell Res. 2008 Apr 15;314(7):1507-18. doi: 10.1016/j.yexcr.2008.01.010. Epub 2008 Jan 19.

PMID:
18314102
21.

The role of signal transducers and activators of transcription in colon cancer.

Klampfer L.

Front Biosci. 2008 Jan 1;13:2888-99. Review.

PMID:
17981761
22.
23.
24.

STAT1-independent inhibition of cyclooxygenase-2 expression by IFNgamma; a common pathway of IFNgamma-mediated gene repression but not gene activation.

Klampfer L, Huang J, Kaler P, Sasazuki T, Shirasawa S, Augenlicht L.

Oncogene. 2007 Mar 29;26(14):2071-81. Epub 2006 Oct 2.

PMID:
17016440
25.

Interaction of genetic and dietary factors in mouse intestinal tumorigenesis.

Augenlicht LH, Yang W, Mariadason J, Velcich A, Klampfer L, Lipkin M, Yang K.

J Nutr. 2006 Oct;136(10):2695S-6S. No abstract available.

PMID:
16988154
26.
27.

Oncogenic Ras increases sensitivity of colon cancer cells to 5-FU-induced apoptosis.

Klampfer L, Swaby LA, Huang J, Sasazuki T, Shirasawa S, Augenlicht L.

Oncogene. 2005 Jun 2;24(24):3932-41.

PMID:
15856030
28.

Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis.

Mariadason JM, Nicholas C, L'Italien KE, Zhuang M, Smartt HJ, Heerdt BG, Yang W, Corner GA, Wilson AJ, Klampfer L, Arango D, Augenlicht LH.

Gastroenterology. 2005 Apr;128(4):1081-8.

PMID:
15825089
29.

Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression.

Klampfer L, Huang J, Sasazuki T, Shirasawa S, Augenlicht L.

J Biol Chem. 2004 Aug 27;279(35):36680-8. Epub 2004 Jun 22.

30.

Requirement of histone deacetylase activity for signaling by STAT1.

Klampfer L, Huang J, Swaby LA, Augenlicht L.

J Biol Chem. 2004 Jul 16;279(29):30358-68. Epub 2004 May 3.

31.

Inhibition of interferon gamma signaling by the short chain fatty acid butyrate.

Klampfer L, Huang J, Sasazuki T, Shirasawa S, Augenlicht L.

Mol Cancer Res. 2003 Sep;1(11):855-62.

32.

Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression.

Klampfer L, Huang J, Corner G, Mariadason J, Arango D, Sasazuki T, Shirasawa S, Augenlicht L.

J Biol Chem. 2003 Nov 21;278(47):46278-87. Epub 2003 Sep 12.

33.

Application of gene expression profiling to colon cell maturation, transformation and chemoprevention.

Augenlicht LH, Velcich A, Klampfer L, Huang J, Corner G, Aranes M, Laboisse C, Rigas B, Lipkin M, Yang K, Shi Q, Lesser M, Heerdt B, Arango D, Yang W, Wilson A, Mariadason JM.

J Nutr. 2003 Jul;133(7 Suppl):2410S-2416S. doi: 10.1093/jn/133.7.2410S. Review.

PMID:
12840217
34.
35.

Sodium salicylate activates caspases and induces apoptosis of myeloid leukemia cell lines.

Klampfer L, Cammenga J, Wisniewski HG, Nimer SD.

Blood. 1999 Apr 1;93(7):2386-94.

PMID:
10090950
36.

The AML1/ETO fusion protein activates transcription of BCL-2.

Klampfer L, Zhang J, Zelenetz AO, Uchida H, Nimer SD.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14059-64.

37.
38.

Activation of the TSG-6 gene by NF-IL6 requires two adjacent NF-IL6 binding sites.

Klampfer L, Chen-Kiang S, Vilcek J.

J Biol Chem. 1995 Feb 24;270(8):3677-82.

39.

NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1.

Klampfer L, Lee TH, Hsu W, Vilcek J, Chen-Kiang S.

Mol Cell Biol. 1994 Oct;14(10):6561-9.

40.

TSG-6: a TNF-, IL-1-, and LPS-inducible secreted glycoprotein associated with arthritis.

Wisniewski HG, Maier R, Lotz M, Lee S, Klampfer L, Lee TH, Vilcek J.

J Immunol. 1993 Dec 1;151(11):6593-601.

PMID:
8245487
42.

Apyrogenic synthetic desmuramyldipeptide, LK-409, with immunomodulatory properties.

Sollner M, Kotnik V, Pecar S, Stace A, Simcic S, Povsic L, Herzog-Wraber B, Klampfer L, Ihan A, Grosman P.

Agents Actions. 1993 Mar;38(3-4):273-80.

PMID:
8213354

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