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Items: 1 to 50 of 94

1.

Structure of the human ClC-1 chloride channel.

Wang K, Preisler SS, Zhang L, Cui Y, Missel JW, Grønberg C, Gotfryd K, Lindahl E, Andersson M, Calloe K, Egea PF, Klaerke DA, Pusch M, Pedersen PA, Zhou ZH, Gourdon P.

PLoS Biol. 2019 Apr 25;17(4):e3000218. doi: 10.1371/journal.pbio.3000218. eCollection 2019 Apr.

2.

PACAP-38 and PACAP(6-38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB3-Receptor.

Pedersen SH, la Cour SH, Calloe K, Hauser F, Olesen J, Klaerke DA, Jansen-Olesen I.

Front Cell Neurosci. 2019 Mar 28;13:114. doi: 10.3389/fncel.2019.00114. eCollection 2019.

3.

Purification of Functional Human TRP Channels Recombinantly Produced in Yeast.

Zhang L, Wang K, Klaerke DA, Calloe K, Lowrey L, Pedersen PA, Gourdon P, Gotfryd K.

Cells. 2019 Feb 11;8(2). pii: E148. doi: 10.3390/cells8020148.

4.

Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel Kv11.1.

Calloe K, Rognant S, Friis S, Shaughnessy C, Klaerke DA, Trachsel D.

Res Vet Sci. 2019 Apr;123:239-246. doi: 10.1016/j.rvsc.2019.01.009. Epub 2019 Jan 8.

PMID:
30685649
5.

Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers.

Klaerke DA, Tejada MLA, Christensen VG, Lassen M, Pedersen PA, Calloe K.

Curr Protoc Pharmacol. 2018 Jun;81(1):e37. doi: 10.1002/cpph.37. Epub 2018 May 4.

PMID:
29927074
6.

Effects of trimethoprim-sulfadiazine and detomidine on the function of equine Kv 11.1 channels in a two-electrode voltage-clamp (TEVC) oocyte model.

Trachsel DS, Tejada MA, Groesfjeld Christensen V, Pedersen PJ, Kanters JK, Buhl R, Calloe K, Klaerke DA.

J Vet Pharmacol Ther. 2018 Aug;41(4):536-545. doi: 10.1111/jvp.12502. Epub 2018 Mar 22.

PMID:
29566261
7.

Corrigendum to "Molecular cloning and functional expression of the K+ channel KV7.1 and the regulatory subunit KCNE1 from equine myocardium" [Res. Vet. Sci. 113 (2017) 79-86].

Pedersen PJ, Thomsen KB, Flak JB, Tejada MA, Hauser F, Trachsel D, Buhl R, Kalbfleisch T, DePriest MS, MacLeod JN, Calloe K, Klaerke DA.

Res Vet Sci. 2018 Jun;118:304. doi: 10.1016/j.rvsc.2017.12.014. Epub 2018 Mar 21. No abstract available.

PMID:
29554586
8.

Molecular cloning and functional expression of the K+ channel KV7.1 and the regulatory subunit KCNE1 from equine myocardium.

Pedersen PJ, Thomsen KB, Flak JB, Tejada MA, Hauser F, Trachsel D, Buhl R, Kalbfleisch T, DePriest MS, MacLeod JN, Calloe K, Klaerke DA.

Res Vet Sci. 2017 Aug;113:79-86. doi: 10.1016/j.rvsc.2017.09.010. Epub 2017 Sep 11. Erratum in: Res Vet Sci. 2018 Mar 16;118:304.

PMID:
28917093
9.

Functional characterization of malaria parasites deficient in the K+ channel Kch2.

Ellekvist P, Mlambo G, Kumar N, Klaerke DA.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):690-696. doi: 10.1016/j.bbrc.2017.08.128. Epub 2017 Aug 30.

10.

Heteromeric Slick/Slack K+ channels show graded sensitivity to cell volume changes.

Tejada MA, Hashem N, Calloe K, Klaerke DA.

PLoS One. 2017 Feb 21;12(2):e0169914. doi: 10.1371/journal.pone.0169914. eCollection 2017.

11.

Differences in the electrocardiographic QT interval of various breeds of athletic horses during rest and exercise.

Pedersen PJ, Karlsson M, Flethøj M, Trachsel DS, Kanters JK, Klaerke DA, Buhl R.

J Vet Cardiol. 2016 Sep;18(3):255-264. doi: 10.1016/j.jvc.2016.02.002. Epub 2016 Apr 7.

PMID:
27068842
12.

Molecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium.

Pedersen PJ, Thomsen KB, Olander ER, Hauser F, Tejada Mde L, Poulsen KL, Grubb S, Buhl R, Calloe K, Klaerke DA.

PLoS One. 2015 Sep 16;10(9):e0138320. doi: 10.1371/journal.pone.0138320. eCollection 2015.

13.

The Mutation P.T613a in the Pore Helix of the Kv 11.1 Potassium Channel is Associated with Long QT Syndrome.

Poulsen KL, Hotait M, Calloe K, Klaerke DA, Rebeiz A, Nemer G, Tejada MA, Refaat MM.

Pacing Clin Electrophysiol. 2015 Nov;38(11):1304-9. doi: 10.1111/pace.12693. Epub 2015 Aug 7.

PMID:
26173150
14.

High yield purification of full-length functional hERG K+ channels produced in Saccharomyces cerevisiae.

Molbaek K, Scharff-Poulsen P, Helix-Nielsen C, Klaerke DA, Pedersen PA.

Microb Cell Fact. 2015 Feb 7;14:15. doi: 10.1186/s12934-015-0193-9.

15.

Cell volume changes regulate slick (Slo2.1), but not slack (Slo2.2) K+ channels.

Tejada MA, Stople K, Hammami Bomholtz S, Meinild AK, Poulsen AN, Klaerke DA.

PLoS One. 2014 Oct 27;9(10):e110833. doi: 10.1371/journal.pone.0110833. eCollection 2014.

16.

Diurnal modulation and sources of variation affecting ventricular repolarization in Warmblood horses.

Pedersen PJ, Moeller SB, Flethøj M, Kanters JK, Buhl R, Klaerke DA.

J Vet Cardiol. 2014 Dec;16(4):265-76. doi: 10.1016/j.jvc.2014.07.001. Epub 2014 Jul 27.

PMID:
25278426
17.

Expression of acute phase proteins and inflammatory cytokines in mouse mammary gland following Staphylococcus aureus challenge and in response to milk accumulation.

Nazemi S, Aalbæk B, Kjelgaard-Hansen M, Safayi S, Klærke DA, Knight CH.

J Dairy Res. 2014 Nov;81(4):445-54. doi: 10.1017/S0022029914000454. Epub 2014 Sep 17.

PMID:
25230141
18.

Reciprocity in the developmental regulation of aquaporins 1, 3 and 5 during pregnancy and lactation in the rat.

Nazemi S, Rahbek M, Parhamifar L, Moghimi SM, Babamoradi H, Mehrdana F, Klærke DA, Knight CH.

PLoS One. 2014 Sep 3;9(9):e106809. doi: 10.1371/journal.pone.0106809. eCollection 2014.

19.

Long-term effect on in vitro cloning efficiency after treatment of somatic cells with Xenopus egg extract in the pig.

Liu Y, Ostrup O, Li R, Li J, Vajta G, Kragh PM, Schmidt M, Purup S, Hyttel P, Klærke D, Callesen H.

Reprod Fertil Dev. 2014 Aug;26(7):1017-31. doi: 10.1071/RD13147.

PMID:
25145414
20.

Expression of the small conductance Ca²⁺-activated potassium channel subtype 3 (SK3) in rat uterus after stimulation with 17β-estradiol.

Rahbek M, Nazemi S, Odum L, Gupta S, Poulsen SS, Hay-Schmidt A, Klaerke DA.

PLoS One. 2014 Feb 5;9(2):e87652. doi: 10.1371/journal.pone.0087652. eCollection 2014.

21.

In vivo studies of aquaporins 3 and 10 in human stratum corneum.

Jungersted JM, Bomholt J, Bajraktari N, Hansen JS, Klærke DA, Pedersen PA, Hedfalk K, Nielsen KH, Agner T, Hélix-Nielsen C.

Arch Dermatol Res. 2013 Oct;305(8):699-704. doi: 10.1007/s00403-013-1365-2. Epub 2013 May 16.

PMID:
23677388
22.

Normal electrocardiographic QT interval in race-fit Standardbred horses at rest and its rate dependence during exercise.

Pedersen PJ, Kanters JK, Buhl R, Klaerke DA.

J Vet Cardiol. 2013 Mar;15(1):23-31. doi: 10.1016/j.jvc.2012.08.002. Epub 2013 Feb 22. Erratum in: J Vet Cardiol. 2013 Sep;15(3):231.

PMID:
23434174
23.

Clofilium inhibits Slick and Slack potassium channels.

de Los Angeles Tejada M, Stolpe K, Meinild AK, Klaerke DA.

Biologics. 2012;6:465-70. doi: 10.2147/BTT.S33827. Epub 2012 Dec 12.

24.

Purinergic signalling - a possible mechanism for KCNQ1 channel response to cell volume challenges.

Hammami S, Willumsen NJ, Meinild AK, Klaerke DA, Novak I.

Acta Physiol (Oxf). 2013 Mar;207(3):503-15. doi: 10.1111/j.1748-1716.2012.02460.x. Epub 2012 Jul 14.

PMID:
22805606
25.

PIP₂ modulation of Slick and Slack K⁺ channels.

de los Angeles Tejada M, Jensen LJ, Klaerke DA.

Biochem Biophys Res Commun. 2012 Jul 27;424(2):208-13. doi: 10.1016/j.bbrc.2012.06.038. Epub 2012 Jun 21.

PMID:
22728883
26.

Remodeling of ribosomal genes in somatic cells by Xenopus egg extract.

Østrup O, Hyttel P, Klærke DA, Collas P.

Biochem Biophys Res Commun. 2011 Sep 2;412(3):487-93. doi: 10.1016/j.bbrc.2011.07.128. Epub 2011 Aug 6.

PMID:
21843509
27.

Neuronal fast activating and meningeal silent modulatory BK channel splice variants cloned from rat.

Poulsen AN, Jansen-Olesen I, Olesen J, Klaerke DA.

Pflugers Arch. 2011 Jan;461(1):65-75. doi: 10.1007/s00424-010-0887-0. Epub 2010 Oct 12.

PMID:
20938677
28.

Localization of large conductance calcium-activated potassium channels and their effect on calcitonin gene-related peptide release in the rat trigemino-neuronal pathway.

Wulf-Johansson H, Amrutkar DV, Hay-Schmidt A, Poulsen AN, Klaerke DA, Olesen J, Jansen-Olesen I.

Neuroscience. 2010 Jun 2;167(4):1091-102. doi: 10.1016/j.neuroscience.2010.02.063. Epub 2010 Mar 6.

PMID:
20211697
29.

Expression of BK Ca channels and the modulatory beta-subunits in the rat and porcine trigeminal ganglion.

Wulf-Johansson H, Hay-Schmidt A, Poulsen AN, Klaerke DA, Olesen J, Jansen-Olesen I.

Brain Res. 2009 Oct 6;1292:1-13. doi: 10.1016/j.brainres.2009.07.047. Epub 2009 Jul 23.

PMID:
19631627
30.

Modulation of Kir4.1 and Kir4.1-Kir5.1 channels by extracellular cations.

Søe R, Andreasen M, Klaerke DA.

Biochim Biophys Acta. 2009 Sep;1788(9):1706-13. doi: 10.1016/j.bbamem.2009.07.002. Epub 2009 Jul 16.

31.

Modulation of Kir4.1 and Kir4.1-Kir5.1 channels by small changes in cell volume.

Soe R, Macaulay N, Klaerke DA.

Neurosci Lett. 2009 Jun 26;457(2):80-4. doi: 10.1016/j.neulet.2009.04.010. Epub 2009 Apr 8.

PMID:
19429167
32.

Triton X-100 inhibits agonist-induced currents and suppresses benzodiazepine modulation of GABA(A) receptors in Xenopus oocytes.

Søgaard R, Ebert B, Klaerke D, Werge T.

Biochim Biophys Acta. 2009 May;1788(5):1073-80. doi: 10.1016/j.bbamem.2009.02.001. Epub 2009 Feb 12.

33.

Molecular investigations of BK(Ca) channels and the modulatory beta-subunits in porcine basilar and middle cerebral arteries.

Wulf H, Hay-Schmidt A, Poulsen AN, Klaerke DA, Olesen J, Jansen-Olesen I.

J Mol Histol. 2009 Apr;40(2):87-97. doi: 10.1007/s10735-009-9216-3. Epub 2009 Apr 1.

PMID:
19337844
34.

Cell volume and membrane stretch independently control K+ channel activity.

Hammami S, Willumsen NJ, Olsen HL, Morera FJ, Latorre R, Klaerke DA.

J Physiol. 2009 May 15;587(Pt 10):2225-31. doi: 10.1113/jphysiol.2008.163550. Epub 2009 Mar 16.

35.

K ATP channels in pig and human intracranial arteries.

Ploug KB, Sørensen MA, Strøbech L, Klaerke DA, Hay-Schmidt A, Sheykhzade M, Olesen J, Jansen-Olesen I.

Eur J Pharmacol. 2008 Dec 28;601(1-3):43-9. doi: 10.1016/j.ejphar.2008.10.041. Epub 2008 Oct 29.

PMID:
18996111
36.

Differential expression of BK channel isoforms and beta-subunits in rat neuro-vascular tissues.

Poulsen AN, Wulf H, Hay-Schmidt A, Jansen-Olesen I, Olesen J, Klaerke DA.

Biochim Biophys Acta. 2009 Feb;1788(2):380-9. doi: 10.1016/j.bbamem.2008.10.001. Epub 2008 Oct 18.

37.

Molecular studies of BKCa channels in intracranial arteries: presence and localization.

Wulf H, Hay-Schmidt A, Poulsen AN, Klaerke DA, Olesen J, Jansen-Olesen I.

Cell Tissue Res. 2008 Dec;334(3):359-69. doi: 10.1007/s00441-008-0701-x. Epub 2008 Oct 25.

PMID:
18953570
38.

Role of K ATP channels in cephalic vasodilatation induced by calcitonin gene-related peptide, nitric oxide, and transcranial electrical stimulation in the rat.

Gozalov A, Jansen-Olesen I, Klaerke D, Olesen J.

Headache. 2008 Sep;48(8):1202-13. doi: 10.1111/j.1526-4610.2008.01205.x. Epub 2008 Jul 21.

PMID:
18647185
39.

Critical role of a K+ channel in Plasmodium berghei transmission revealed by targeted gene disruption.

Ellekvist P, Maciel J, Mlambo G, Ricke CH, Colding H, Klaerke DA, Kumar N.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6398-402. doi: 10.1073/pnas.0802384105. Epub 2008 Apr 23.

40.

The KCNE1 beta-subunit exerts a transient effect on the KCNQ1 K+ channel.

Poulsen AN, Klaerke DA.

Biochem Biophys Res Commun. 2007 Nov 9;363(1):133-9. Epub 2007 Aug 31.

PMID:
17845799
41.

Role of BK(Ca) channels in cephalic vasodilation induced by CGRP, NO and transcranial electrical stimulation in the rat.

Gozalov A, Jansen-Olesen I, Klaerke D, Olesen J.

Cephalalgia. 2007 Oct;27(10):1120-7. Epub 2007 Aug 21.

PMID:
17714519
42.

Characterization of transport mechanisms and determinants critical for Na+-dependent Pi symport of the PiT family paralogs human PiT1 and PiT2.

Bøttger P, Hede SE, Grunnet M, Høyer B, Klaerke DA, Pedersen L.

Am J Physiol Cell Physiol. 2006 Dec;291(6):C1377-87. Epub 2006 Jun 21.

43.

The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?

Jespersen T, Grunnet M, Rasmussen HB, Jørgensen NB, Jensen HS, Angelo K, Olesen SP, Klaerke DA.

Biochem Biophys Res Commun. 2006 Mar 24;341(4):979-88. Epub 2006 Jan 24.

PMID:
16476578
44.

A new family of insect tyramine receptors.

Cazzamali G, Klaerke DA, Grimmelikhuijzen CJ.

Biochem Biophys Res Commun. 2005 Dec 16;338(2):1189-96. Epub 2005 Oct 21.

PMID:
16274665
45.

P2Y2 and P2Y4 receptors regulate pancreatic Ca(2+)-activated K+ channels differently.

Hede SE, Amstrup J, Klaerke DA, Novak I.

Pflugers Arch. 2005 Sep;450(6):429-36. Epub 2005 Jun 17.

PMID:
16075244
46.

Quantification and distribution of big conductance Ca2+-activated K+ channels in kidney epithelia.

Grunnet M, Hay-Schmidt A, Klaerke DA.

Biochim Biophys Acta. 2005 Aug 15;1714(2):114-24.

47.

NH3 and NH4+ permeability in aquaporin-expressing Xenopus oocytes.

Holm LM, Jahn TP, Møller AL, Schjoerring JK, Ferri D, Klaerke DA, Zeuthen T.

Pflugers Arch. 2005 Sep;450(6):415-28. Epub 2005 Jun 30.

PMID:
15988592
48.

Role of KATP channels in the regulation of rat dura and pia artery diameter.

Gozalov A, Petersen KA, Mortensen C, Jansen-Olesen I, Klaerke D, Olesen J.

Cephalalgia. 2005 Apr;25(4):249-60.

PMID:
15773822
49.

hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics.

Grunnet M, Olesen SP, Klaerke DA, Jespersen T.

Biochem Biophys Res Commun. 2005 Mar 25;328(4):1146-53.

PMID:
15707997
50.

Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels.

Dupuis DS, Klaerke DA, Olesen SP.

Basic Clin Pharmacol Toxicol. 2005 Feb;96(2):123-30.

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