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Items: 1 to 50 of 75

1.

A Benzophenone-Based Photocaging Strategy for the N7 Position of Guanosine.

Anhäuser L, Klöcker N, Muttach F, Mäsing F, Špaček P, Studer A, Rentmeister A.

Angew Chem Int Ed Engl. 2020 Feb 17;59(8):3161-3165. doi: 10.1002/anie.201914573. Epub 2019 Dec 30.

2.

Hepatic encephalopathy is linked to alterations of autophagic flux in astrocytes.

Lu K, Zimmermann M, Görg B, Bidmon HJ, Biermann B, Klöcker N, Häussinger D, Reichert AS.

EBioMedicine. 2019 Oct;48:539-553. doi: 10.1016/j.ebiom.2019.09.058. Epub 2019 Oct 21.

3.

Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers.

Trads JB, Hüll K, Matsuura BS, Laprell L, Fehrentz T, Görldt N, Kozek KA, Weaver CD, Klöcker N, Barber DM, Trauner D.

Angew Chem Int Ed Engl. 2019 Oct 21;58(43):15421-15428. doi: 10.1002/anie.201905790. Epub 2019 Sep 12. Review.

PMID:
31441199
4.

Isoform-specific Inhibition of N-methyl-D-aspartate Receptors by Bile Salts.

Koch A, Bonus M, Gohlke H, Klöcker N.

Sci Rep. 2019 Jul 11;9(1):10068. doi: 10.1038/s41598-019-46496-y.

5.

Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation.

Scherschel K, Hedenus K, Jungen C, Lemoine MD, Rübsamen N, Veldkamp MW, Klatt N, Lindner D, Westermann D, Casini S, Kuklik P, Eickholt C, Klöcker N, Shivkumar K, Christ T, Zeller T, Willems S, Meyer C.

Sci Transl Med. 2019 May 22;11(493). pii: eaav7770. doi: 10.1126/scitranslmed.aav7770.

PMID:
31118294
6.

Heterogeneity of the astrocytic AMPA-receptor transcriptome.

Mölders A, Koch A, Menke R, Klöcker N.

Glia. 2018 Dec;66(12):2604-2616. doi: 10.1002/glia.23514. Epub 2018 Oct 28.

PMID:
30370555
7.

Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction.

Haselmann H, Mannara F, Werner C, Planagumà J, Miguez-Cabello F, Schmidl L, Grünewald B, Petit-Pedrol M, Kirmse K, Classen J, Demir F, Klöcker N, Soto D, Doose S, Dalmau J, Hallermann S, Geis C.

Neuron. 2018 Oct 10;100(1):91-105.e9. doi: 10.1016/j.neuron.2018.07.048. Epub 2018 Aug 23.

8.

A modified approach for programmed electrical stimulation in mice: Inducibility of ventricular arrhythmias.

Clasen L, Eickholt C, Angendohr S, Jungen C, Shin DI, Donner B, Fürnkranz A, Kelm M, Klöcker N, Meyer C, Makimoto H.

PLoS One. 2018 Aug 22;13(8):e0201910. doi: 10.1371/journal.pone.0201910. eCollection 2018.

9.

Optical control of L-type Ca2+ channels using a diltiazem photoswitch.

Fehrentz T, Huber FME, Hartrampf N, Bruegmann T, Frank JA, Fine NHF, Malan D, Danzl JG, Tikhonov DB, Sumser M, Sasse P, Hodson DJ, Zhorov BS, Klöcker N, Trauner D.

Nat Chem Biol. 2018 Aug;14(8):764-767. doi: 10.1038/s41589-018-0090-8. Epub 2018 Jul 16.

PMID:
30013061
10.

Multiple DNA damage-dependent and DNA damage-independent stress responses define the outcome of ATR/Chk1 targeting in medulloblastoma cells.

Krüger K, Geist K, Stuhldreier F, Schumacher L, Blümel L, Remke M, Wesselborg S, Stork B, Klöcker N, Bormann S, Roos WP, Honnen S, Fritz G.

Cancer Lett. 2018 Aug 28;430:34-46. doi: 10.1016/j.canlet.2018.05.011. Epub 2018 May 16.

PMID:
29753759
11.

NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody.

Malviya M, Barman S, Golombeck KS, Planagumà J, Mannara F, Strutz-Seebohm N, Wrzos C, Demir F, Baksmeier C, Steckel J, Falk KK, Gross CC, Kovac S, Bönte K, Johnen A, Wandinger KP, Martín-García E, Becker AJ, Elger CE, Klöcker N, Wiendl H, Meuth SG, Hartung HP, Seebohm G, Leypoldt F, Maldonado R, Stadelmann C, Dalmau J, Melzer N, Goebels N.

Ann Clin Transl Neurol. 2017 Oct 3;4(11):768-783. doi: 10.1002/acn3.444. eCollection 2017 Nov.

12.

Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias.

Jungen C, Scherschel K, Eickholt C, Kuklik P, Klatt N, Bork N, Salzbrunn T, Alken F, Angendohr S, Klene C, Mester J, Klöcker N, Veldkamp MW, Schumacher U, Willems S, Nikolaev VO, Meyer C.

Nat Commun. 2017 Jan 27;8:14155. doi: 10.1038/ncomms14155.

13.

Impaired novelty acquisition and synaptic plasticity in congenital hyperammonemia caused by hepatic glutamine synthetase deficiency.

Chepkova AN, Sergeeva OA, Görg B, Haas HL, Klöcker N, Häussinger D.

Sci Rep. 2017 Jan 9;7:40190. doi: 10.1038/srep40190.

14.

Depletion of the AMPAR reserve pool impairs synaptic plasticity in a model of hepatic encephalopathy.

Schroeter A, Wen S, Mölders A, Erlenhardt N, Stein V, Klöcker N.

Mol Cell Neurosci. 2015 Sep;68:331-9. doi: 10.1016/j.mcn.2015.09.001. Epub 2015 Sep 9.

PMID:
26363416
15.

Pleiotropic, heart rate-independent cardioprotection by ivabradine.

Kleinbongard P, Gedik N, Witting P, Freedman B, Klöcker N, Heusch G.

Br J Pharmacol. 2015 Sep;172(17):4380-90. doi: 10.1111/bph.13220. Epub 2015 Jul 21.

16.

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.

Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen MS, Stožer A, Wnendt S, Piemonti L, Köhler M, Ferrer J, Thorens B, Schliess F, Rupnik MS, Heise T, Berggren PO, Klöcker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E.

Nat Med. 2015 Apr;21(4):363-72. doi: 10.1038/nm.3822. Epub 2015 Mar 16.

PMID:
25774850
17.

Synaptic plasticity in hepatic encephalopathy - a molecular perspective.

Wen S, Schroeter A, Klöcker N.

Arch Biochem Biophys. 2013 Aug 15;536(2):183-8. doi: 10.1016/j.abb.2013.04.008. Epub 2013 Apr 25. Review.

PMID:
23624147
18.

Ontogeny repeats the phylogenetic recruitment of the cargo exporter cornichon into AMPA receptor signaling complexes.

Mauric V, Mölders A, Harmel N, Heimrich B, Sergeeva OA, Klöcker N.

Mol Cell Neurosci. 2013 Sep;56:10-7. doi: 10.1016/j.mcn.2013.02.001. Epub 2013 Feb 8.

PMID:
23403072
19.

The HCN4 channel mutation D553N associated with bradycardia has a C-linker mediated gating defect.

Netter MF, Zuzarte M, Schlichthörl G, Klöcker N, Decher N.

Cell Physiol Biochem. 2012;30(5):1227-40. doi: 10.1159/000343314. Epub 2012 Oct 15.

20.

High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.

Schwenk J, Harmel N, Brechet A, Zolles G, Berkefeld H, Müller CS, Bildl W, Baehrens D, Hüber B, Kulik A, Klöcker N, Schulte U, Fakler B.

Neuron. 2012 May 24;74(4):621-33. doi: 10.1016/j.neuron.2012.03.034.

21.

AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling.

Harmel N, Cokic B, Zolles G, Berkefeld H, Mauric V, Fakler B, Stein V, Klöcker N.

PLoS One. 2012;7(1):e30681. doi: 10.1371/journal.pone.0030681. Epub 2012 Jan 24.

22.

[Elderly need an adapted cancer pain therapy].

Wirz S, Wartenberg HC, Schenk M, Weckbecker K, Klöcker N, Junker U.

MMW Fortschr Med. 2009 Nov 19;151(47):87-90; quiz 91. German. No abstract available.

PMID:
20037985
23.

Association with the auxiliary subunit PEX5R/Trip8b controls responsiveness of HCN channels to cAMP and adrenergic stimulation.

Zolles G, Wenzel D, Bildl W, Schulte U, Hofmann A, Müller CS, Thumfart JO, Vlachos A, Deller T, Pfeifer A, Fleischmann BK, Roeper J, Fakler B, Klöcker N.

Neuron. 2009 Jun 25;62(6):814-25. doi: 10.1016/j.neuron.2009.05.008.

24.

Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors.

Schwenk J, Harmel N, Zolles G, Bildl W, Kulik A, Heimrich B, Chisaka O, Jonas P, Schulte U, Fakler B, Klöcker N.

Science. 2009 Mar 6;323(5919):1313-9. doi: 10.1126/science.1167852.

25.

Prolonged irradiation of enhanced cyan fluorescent protein or Cerulean can invalidate Forster resonance energy transfer measurements.

Hoffmann B, Zimmer T, Klöcker N, Kelbauskas L, König K, Benndorf K, Biskup C.

J Biomed Opt. 2008 May-Jun;13(3):031205. doi: 10.1117/1.2937829.

26.

Localization, trafficking, and significance for acid secretion of parietal cell Kir4.1 and KCNQ1 K+ channels.

Kaufhold MA, Krabbenhöft A, Song P, Engelhardt R, Riederer B, Fährmann M, Klöcker N, Beil W, Manns M, Hagen SJ, Seidler U.

Gastroenterology. 2008 Apr;134(4):1058-69. doi: 10.1053/j.gastro.2008.01.033. Epub 2008 Jan 18.

PMID:
18395087
27.

Recycling endosomes supply cardiac pacemaker channels for regulated surface expression.

Hardel N, Harmel N, Zolles G, Fakler B, Klöcker N.

Cardiovasc Res. 2008 Jul 1;79(1):52-60. doi: 10.1093/cvr/cvn062. Epub 2008 Mar 7.

PMID:
18326556
28.

Multi-dimensional fluorescence lifetime and FRET measurements.

Biskup C, Zimmer T, Kelbauskas L, Hoffmann B, Klöcker N, Becker W, Bergmann A, Benndorf K.

Microsc Res Tech. 2007 May;70(5):442-51.

PMID:
17393489
29.

Pacemaking by HCN channels requires interaction with phosphoinositides.

Zolles G, Klöcker N, Wenzel D, Weisser-Thomas J, Fleischmann BK, Roeper J, Fakler B.

Neuron. 2006 Dec 21;52(6):1027-36.

30.

Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels.

Shumilina E, Klöcker N, Korniychuk G, Rapedius M, Lang F, Baukrowitz T.

J Physiol. 2006 Sep 1;575(Pt 2):433-42. Epub 2006 Jun 15.

31.

Fluorescence lifetime images and correlation spectra obtained by multidimensional time-correlated single photon counting.

Becker W, Bergmann A, Haustein E, Petrasek Z, Schwille P, Biskup C, Kelbauskas L, Benndorf K, Klöcker N, Anhut T, Riemann I, König K.

Microsc Res Tech. 2006 Mar;69(3):186-95.

PMID:
16538624
32.

The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.

Schulte U, Thumfart JO, Klöcker N, Sailer CA, Bildl W, Biniossek M, Dehn D, Deller T, Eble S, Abbass K, Wangler T, Knaus HG, Fakler B.

Neuron. 2006 Mar 2;49(5):697-706.

33.

[Comparison of two application forms for isotonic sodium-chloride solution in postoperative sinus-surgery wound care].

Scheithauer MO, Scheithauer I, Klöcker N, Verse T.

Laryngorhinootologie. 2006 Jan;85(1):14-9. German.

PMID:
16444650
34.

Dystroglycan and Kir4.1 coclustering in retinal Müller glia is regulated by laminin-1 and requires the PDZ-ligand domain of Kir4.1.

Noël G, Belda M, Guadagno E, Micoud J, Klöcker N, Moukhles H.

J Neurochem. 2005 Aug;94(3):691-702.

35.
36.

Selective Golgi export of Kir2.1 controls the stoichiometry of functional Kir2.x channel heteromers.

Hofherr A, Fakler B, Klöcker N.

J Cell Sci. 2005 May 1;118(Pt 9):1935-43. Epub 2005 Apr 12.

37.

Cod106, a novel synaptic protein expressed in sensory hair cells of the inner ear and in CNS neurons.

Reisinger E, Zimmermann U, Knipper M, Ludwig J, Klöcker N, Fakler B, Oliver D.

Mol Cell Neurosci. 2005 Jan;28(1):106-17.

PMID:
15607946
38.
39.
40.

Interaction of PSD-95 with potassium channels visualized by fluorescence lifetime-based resonance energy transfer imaging.

Biskup C, Kelbauskas L, Zimmer T, Benndorf K, Bergmann A, Becker W, Ruppersberg JP, Stockklausner C, Klöcker N.

J Biomed Opt. 2004 Jul-Aug;9(4):753-9.

41.

N-linked glycosylation sites of the motor protein prestin: effects on membrane targeting and electrophysiological function.

Matsuda K, Zheng J, Du GG, Klöcker N, Madison LD, Dallos P.

J Neurochem. 2004 May;89(4):928-38.

42.

Antimicrobial safety of a preservative-free nasal multiple-dose drug administration system.

Klöcker N, Kramer A, Verse T, Sikora C, Rudolph P, Daeschlein G.

Eur J Pharm Biopharm. 2004 May;57(3):489-93.

PMID:
15093598
44.

[The tolerability of nasal drugs with special regard to preservatives and physico-chemical parameters].

Verse T, Sikora C, Rudolph P, Klöcker N.

Laryngorhinootologie. 2003 Nov;82(11):782-9. German.

PMID:
14634896
45.

[The protective effect of dexpanthenol in nasal sprays. First results of cytotoxic and ciliary-toxic studies in vitro].

Klöcker N, Verse T, Rudolph P.

Laryngorhinootologie. 2003 Mar;82(3):177-82. German.

PMID:
12673516
46.

Surface expression of inward rectifier potassium channels is controlled by selective Golgi export.

Stockklausner C, Klocker N.

J Biol Chem. 2003 May 9;278(19):17000-5. Epub 2003 Feb 27.

47.

Synaptic glutamate receptor clustering in mice lacking the SH3 and GK domains of SAP97.

Klöcker N, Bunn RC, Schnell E, Caruana G, Bernstein A, Nicoll RA, Bredt DS.

Eur J Neurosci. 2002 Oct;16(8):1517-22.

PMID:
12405965
48.

A helical region in the C terminus of small-conductance Ca2+-activated K+ channels controls assembly with apo-calmodulin.

Wissmann R, Bildl W, Neumann H, Rivard AF, Klöcker N, Weitz D, Schulte U, Adelman JP, Bentrop D, Fakler B.

J Biol Chem. 2002 Feb 8;277(6):4558-64. Epub 2001 Nov 26.

50.

Morphological and functional analysis of an incomplete CNS fiber tract lesion: graded crush of the rat optic nerve.

Klöcker N, Zerfowski M, Gellrich NC, Bähr M.

J Neurosci Methods. 2001 Sep 30;110(1-2):147-53.

PMID:
11564535

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