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Items: 1 to 50 of 103

1.

Infarct-Related Ventricular Tachycardia: Redefining the Electrophysiological Substrate of the Isthmus During Sinus Rhythm.

Anter E, Kleber AG, Rottmann M, Leshem E, Barkagan M, Tschabrunn CM, Contreras-Valdes FM, Buxton AE.

JACC Clin Electrophysiol. 2018 Aug;4(8):1033-1048. doi: 10.1016/j.jacep.2018.04.007. Epub 2018 Jun 27.

PMID:
30139485
2.

GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs.

Basheer WA, Xiao S, Epifantseva I, Fu Y, Kleber AG, Hong T, Shaw RM.

Circ Res. 2017 Oct 13;121(9):1069-1080. doi: 10.1161/CIRCRESAHA.117.311955. Epub 2017 Sep 18.

3.

Microstructure, Cell-to-Cell Coupling, and Ion Currents as Determinants of Electrical Propagation and Arrhythmogenesis.

Kucera JP, Rohr S, Kleber AG.

Circ Arrhythm Electrophysiol. 2017 Sep;10(9). pii: e004665. doi: 10.1161/CIRCEP.117.004665. Review. No abstract available.

PMID:
28912204
4.

Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy.

Chelko SP, Asimaki A, Andersen P, Bedja D, Amat-Alarcon N, DeMazumder D, Jasti R, MacRae CA, Leber R, Kleber AG, Saffitz JE, Judge DP.

JCI Insight. 2016 Apr 21;1(5). pii: 85923. doi: 10.1172/jci.insight.85923.

5.

Characterizing the Molecular Pathology of Arrhythmogenic Cardiomyopathy in Patient Buccal Mucosa Cells.

Asimaki A, Protonotarios A, James CA, Chelko SP, Tichnell C, Murray B, Tsatsopoulou A, Anastasakis A, te Riele A, Kléber AG, Judge DP, Calkins H, Saffitz JE.

Circ Arrhythm Electrophysiol. 2016 Feb;9(2):e003688. doi: 10.1161/CIRCEP.115.003688.

6.

Pathogenesis of Arrhythmogenic Cardiomyopathy.

Asimaki A, Kleber AG, Saffitz JE.

Can J Cardiol. 2015 Nov;31(11):1313-24. doi: 10.1016/j.cjca.2015.04.012. Epub 2015 Apr 24. Review.

7.

Arrhythmogenic Cardiomyopathy - New Insights into Disease Mechanisms and Drug Discovery.

Asimaki A, Kléber AG, MacRae CA, Saffitz JE.

Prog Pediatr Cardiol. 2014 Dec 1;37(1-2):3-7.

8.

Role of the intercalated disc in cardiac propagation and arrhythmogenesis.

Kleber AG, Saffitz JE.

Front Physiol. 2014 Oct 17;5:404. doi: 10.3389/fphys.2014.00404. eCollection 2014. Review.

9.

Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy.

Asimaki A, Kapoor S, Plovie E, Karin Arndt A, Adams E, Liu Z, James CA, Judge DP, Calkins H, Churko J, Wu JC, MacRae CA, Kléber AG, Saffitz JE.

Sci Transl Med. 2014 Jun 11;6(240):240ra74. doi: 10.1126/scitranslmed.3008008. Erratum in: Sci Transl Med. 2014 Nov 5;6(261):261er6.

10.

Engineering cardiac cell junctions in vitro to study the intercalated disc.

McCain ML, Desplantez T, Kléber AG.

Cell Commun Adhes. 2014 Jun;21(3):181-91. doi: 10.3109/15419061.2014.905931. Epub 2014 Apr 23. Review.

PMID:
24754499
11.

A micropatterning approach for imaging dynamic Cx43 trafficking to cell-cell borders.

Zhang SS, Hong S, Kléber AG, Lee LP, Shaw RM.

FEBS Lett. 2014 Apr 17;588(8):1439-45. doi: 10.1016/j.febslet.2014.01.002. Epub 2014 Jan 17.

12.

Gap junctions, slow conduction, and ventricular tachycardia after myocardial infarction.

Saffitz JE, Kléber AG.

J Am Coll Cardiol. 2012 Sep 18;60(12):1111-3. doi: 10.1016/j.jacc.2012.05.020. Epub 2012 Aug 8. No abstract available.

13.

The works of Dirk Durrer (1918-1984).

Opthof T, Janse MJ, Kléber AG, Wellens HJ, Wilde AA, Coronel R.

Neth Heart J. 2012 Oct;20(10):430-3. doi: 10.1007/s12471-012-0313-7. No abstract available.

14.

Cooperative coupling of cell-matrix and cell-cell adhesions in cardiac muscle.

McCain ML, Lee H, Aratyn-Schaus Y, Kléber AG, Parker KK.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9881-6. doi: 10.1073/pnas.1203007109. Epub 2012 Jun 6.

15.

Electrical coupling and propagation in engineered ventricular myocardium with heterogeneous expression of connexin43.

Beauchamp P, Desplantez T, McCain ML, Li W, Asimaki A, Rigoli G, Parker KK, Saffitz JE, Kleber AG.

Circ Res. 2012 May 25;110(11):1445-53. doi: 10.1161/CIRCRESAHA.111.259705. Epub 2012 Apr 19.

16.

Virtual sources and sinks during extracellular field shocks in cardiac cell cultures: effects of source-sink interactions between adjacent tissue boundaries.

Kondratyev AA, Didon JP, Hinnen-Oberer H, Lemay M, Kucera JP, Kleber AG.

Circ Arrhythm Electrophysiol. 2012 Apr;5(2):391-9. doi: 10.1161/CIRCEP.111.968180. Epub 2012 Mar 2.

PMID:
22387879
17.

Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current.

Desplantez T, McCain ML, Beauchamp P, Rigoli G, Rothen-Rutishauser B, Parker KK, Kleber AG.

Cardiovasc Res. 2012 Apr 1;94(1):58-65. doi: 10.1093/cvr/cvs025. Epub 2012 Jan 27.

18.

Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance.

McCain ML, Desplantez T, Geisse NA, Rothen-Rutishauser B, Oberer H, Parker KK, Kleber AG.

Am J Physiol Heart Circ Physiol. 2012 Jan;302(2):H443-50. doi: 10.1152/ajpheart.01218.2010. Epub 2011 Nov 11.

19.

Gap junctions and conduction of cardiac excitation.

Kléber AG.

Heart Rhythm. 2011 Dec;8(12):1981-4. doi: 10.1016/j.hrthm.2011.08.007. Epub 2011 Aug 9. Review. No abstract available.

PMID:
21835153
20.

Ascona Workshop on Cardiomyocyte Biology: highlights from the Sixth International Workshop.

Schaub MC, Kléber AG.

J Cardiovasc Pharmacol. 2010 Jul;56(1):1-5. doi: 10.1097/FJC.0b013e3181ebafe1. No abstract available.

PMID:
20588191
21.
22.

Na+ channel transfection to rescue propagation.

Kléber AG.

Heart Rhythm. 2010 Aug;7(8):1111-2. doi: 10.1016/j.hrthm.2010.05.007. Epub 2010 May 11. No abstract available.

PMID:
20466071
23.

Crosstalk between theoretical and experimental studies for the understanding of cardiac electrical impulse propagation.

Kléber AG.

J Electrocardiol. 2007 Nov-Dec;40(6 Suppl):S136-41. Review. No abstract available.

PMID:
17993310
24.

Cardiac cell-to-cell junctions as an origin of inherited arrhythmogenic disorders.

Kléber AG.

Heart Rhythm. 2007 Sep;4(9):1206-7. Epub 2007 Jun 16. No abstract available.

PMID:
17765622
25.

Adenoviral expression of IKs contributes to wavebreak and fibrillatory conduction in neonatal rat ventricular cardiomyocyte monolayers.

Muñoz V, Grzeda KR, Desplantez T, Pandit SV, Mironov S, Taffet SM, Rohr S, Kléber AG, Jalife J.

Circ Res. 2007 Aug 31;101(5):475-83. Epub 2007 Jul 12.

PMID:
17626898
26.

Relative contributions of connexins 40 and 43 to atrial impulse propagation in synthetic strands of neonatal and fetal murine cardiomyocytes.

Beauchamp P, Yamada KA, Baertschi AJ, Green K, Kanter EM, Saffitz JE, Kléber AG.

Circ Res. 2006 Nov 24;99(11):1216-24. Epub 2006 Oct 19.

PMID:
17053190
27.

Electrical coupling of cardiac myocyte cell sheets to the heart.

Eschenhagen T, Zimmermann WH, Kléber AG.

Circ Res. 2006 Mar 17;98(5):573-5. No abstract available.

PMID:
16543504
28.

The early years of cellular cardiac electrophysiology and Silvio Weidmann (1921-2005).

Kléber AG, Niggli E, McGuigan JA, Weingart R.

Heart Rhythm. 2006 Mar;3(3):353-9. No abstract available.

PMID:
16500311
29.
30.

Electrical propagation in synthetic ventricular myocyte strands from germline connexin43 knockout mice.

Beauchamp P, Choby C, Desplantez T, de Peyer K, Green K, Yamada KA, Weingart R, Saffitz JE, Kléber AG.

Circ Res. 2004 Jul 23;95(2):170-8. Epub 2004 Jun 10.

PMID:
15192022
31.

Basic mechanisms of cardiac impulse propagation and associated arrhythmias.

Kléber AG, Rudy Y.

Physiol Rev. 2004 Apr;84(2):431-88. Review.

32.

Effects of mechanical forces and mediators of hypertrophy on remodeling of gap junctions in the heart.

Saffitz JE, Kléber AG.

Circ Res. 2004 Mar 19;94(5):585-91. Review.

PMID:
15031271
33.

From the needle to the optrode: assessment of cardiac intramural electrical activity.

Kleber AG.

J Cardiovasc Electrophysiol. 2003 Nov;14(11):1203-4. No abstract available.

PMID:
14678135
34.

Cell-to-cell coupling between host and donor cells in the in situ myocardium.

Kléber AG.

Circ Res. 2003 Jun 13;92(11):1176-8. No abstract available.

PMID:
12805234
35.

Impulse propagation in synthetic strands of neonatal cardiac myocytes with genetically reduced levels of connexin43.

Thomas SP, Kucera JP, Bircher-Lehmann L, Rudy Y, Saffitz JE, Kléber AG.

Circ Res. 2003 Jun 13;92(11):1209-16. Epub 2003 May 1.

36.

Autocrine regulation of myocyte Cx43 expression by VEGF.

Pimentel RC, Yamada KA, Kléber AG, Saffitz JE.

Circ Res. 2002 Apr 5;90(6):671-7.

PMID:
11934834
37.

Slow conduction in cardiac tissue: insights from optical mapping at the cellular level.

Kucera JP, Kléber AG, Rohr S.

J Electrocardiol. 2001;34 Suppl:57-64.

PMID:
11781937
38.

Real time, confocal imaging of Ca(2+) waves in arterially perfused rat hearts.

Baader AP, Büchler L, Bircher-Lehmann L, Kléber AG.

Cardiovasc Res. 2002 Jan;53(1):105-15.

PMID:
11744018
39.

Pathophysiology and prevention of atrial fibrillation.

Allessie MA, Boyden PA, Camm AJ, Kléber AG, Lab MJ, Legato MJ, Rosen MR, Schwartz PJ, Spooner PM, Van Wagoner DR, Waldo AL.

Circulation. 2001 Feb 6;103(5):769-77. Review. No abstract available.

PMID:
11156892
40.

The fibrillating atrial myocardium. What can the detection of wave breaks tell us?

Kleber AG.

Cardiovasc Res. 2000 Nov;48(2):181-4. No abstract available.

PMID:
11054463
41.

Dephosphorylation and intracellular redistribution of ventricular connexin43 during electrical uncoupling induced by ischemia.

Beardslee MA, Lerner DL, Tadros PN, Laing JG, Beyer EC, Yamada KA, Kléber AG, Schuessler RB, Saffitz JE.

Circ Res. 2000 Oct 13;87(8):656-62.

PMID:
11029400
42.

Virtual sources associated with linear and curved strands of cardiac cells.

Tung L, Kléber AG.

Am J Physiol Heart Circ Physiol. 2000 Oct;279(4):H1579-90.

43.

Synthetic strands of neonatal mouse cardiac myocytes: structural and electrophysiological properties.

Thomas SP, Bircher-Lehmann L, Thomas SA, Zhuang J, Saffitz JE, Kléber AG.

Circ Res. 2000 Sep 15;87(6):467-73.

PMID:
10988238
44.

Pulsatile stretch remodels cell-to-cell communication in cultured myocytes.

Zhuang J, Yamada KA, Saffitz JE, Kléber AG.

Circ Res. 2000 Aug 18;87(4):316-22.

PMID:
10948066
45.

Optical recording of impulse propagation in designer cultures. Cardiac tissue architectures inducing ultra-slow conduction.

Rohr S, Kléber AG, Kucera JP.

Trends Cardiovasc Med. 1999 Oct;9(7):173-9. Review.

PMID:
10881747
46.
47.

ST-segment elevation in the electrocardiogram: a sign of myocardial ischemia.

Kléber AG.

Cardiovasc Res. 2000 Jan 1;45(1):111-8. Review.

PMID:
10728321
48.

Discontinuous propagation of the cardiac impulse and arrhythmogenesis.

Kléber AG.

J Cardiovasc Electrophysiol. 1999 Jul;10(7):1025-7. Review. No abstract available.

PMID:
10413383
49.

Genetic and molecular basis of cardiac arrhythmias; impact on clinical management. Study group on molecular basis of arrhythmias of the working group on arrhythmias of the european society of cardiology.

Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde A.

Eur Heart J. 1999 Feb;20(3):174-95. Review. No abstract available.

PMID:
10082151
50.

Genetic and molecular basis of cardiac arrhythmias: impact on clinical management part III.

Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde AM.

Circulation. 1999 Feb 9;99(5):674-81. Review. No abstract available.

PMID:
9950666

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