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Items: 1 to 50 of 95

1.

TransCon CNP, a sustained-release C-Type Natriuretic Peptide prodrug, a potentially safe and efficacious new therapeutic modality for the treatment of comorbidities associated with FGFR3-related skeletal dysplasias.

Breinholt VM, Rasmussen CE, Mygind PH, Kjelgaard-Hansen M, Faltinger F, Bernhard A, Zettler J, Hersel U.

J Pharmacol Exp Ther. 2019 Jun 24. pii: jpet.119.258251. doi: 10.1124/jpet.119.258251. [Epub ahead of print]

2.

Gene-based FVIIa prophylaxis modulates the spontaneous bleeding phenotype of hemophilia A rats.

Zintner SM, Small JC, Pavani G, Dankner L, Marcos-Contreras OA, Gimotty PA, Kjelgaard-Hansen M, Wiinberg B, Margaritis P.

Blood Adv. 2019 Feb 12;3(3):301-311. doi: 10.1182/bloodadvances.2018027219.

3.

Bleed volume of experimental knee haemarthrosis correlates with the subsequent degree of haemophilic arthropathy.

Vøls KK, Kjelgaard-Hansen M, Ley CD, Hansen AK, Petersen M.

Haemophilia. 2019 Mar;25(2):324-333. doi: 10.1111/hae.13672. Epub 2019 Jan 16.

PMID:
30648774
4.

Rapid inflammation and early degeneration of bone and cartilage revealed in a time-course study of induced haemarthrosis in haemophilic rats.

Christensen KR, Kjelgaard-Hansen M, Nielsen LN, Wiinberg B, Alexander Althoehn F, Bloksgaard Poulsen N, Kryger Vøls K, Popp Thyme A, Maria Lövgren K, Kornerup Hansen A, Roepstorff K.

Rheumatology (Oxford). 2019 Apr 1;58(4):588-599. doi: 10.1093/rheumatology/key186.

PMID:
29982826
5.

C-reactive protein, glucose and iron concentrations are significantly altered in dogs undergoing open ovariohysterectomy or ovariectomy.

Moldal ER, Kjelgaard-Hansen MJ, Peeters ME, Nødtvedt A, Kirpensteijn J.

Acta Vet Scand. 2018 May 30;60(1):32. doi: 10.1186/s13028-018-0384-6.

6.

Usefulness of C-reactive protein and serum amyloid A in early detection of postoperative infectious complications to tibial plateau leveling osteotomy in dogs.

Löfqvist K, Kjelgaard-Hansen M, Nielsen MBM.

Acta Vet Scand. 2018 May 21;60(1):30. doi: 10.1186/s13028-018-0385-5.

7.

THROMBOELASTOGRAPHY IN THE HEALTHY ASIAN ELEPHANT ( ELEPHAS MAXIMUS): REFERENCE INTERVALS AND EFFECTS OF STORAGE.

Perrin KL, Krogh AK, Kjelgaard-Hansen M, Howard L, Bochsen L, Kiso WK, Schmitt D, Kristensen AT, Bertelsen MF.

J Zoo Wildl Med. 2018 Mar;49(1):54-63. doi: 10.1638/2017-0179R.1.

PMID:
29517458
8.

Engineering of a membrane-triggered activity switch in coagulation factor VIIa.

Nielsen AL, Sorensen AB, Holmberg HL, Gandhi PS, Karlsson J, Buchardt J, Lamberth K, Kjelgaard-Hansen M, Ley CD, Sørensen BB, Ruf W, Olsen OH, Østergaard H.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12454-12459. doi: 10.1073/pnas.1618713114. Epub 2017 Nov 6.

9.

Increased basement membrane turnover and strongly attenuated interstitial matrix turnover is a key pathological feature of haemophilia.

Manon-Jensen T, Hua BL, Olsen EHN, Sun S, Gudme CN, Li J, Lei W, Vandahl B, Roepstorff K, Kjelgaard-Hansen M, Zhao Y, Karsdal MA.

Haemophilia. 2017 Nov;23(6):e515-e518. doi: 10.1111/hae.13329. Epub 2017 Aug 29. No abstract available.

PMID:
28851078
10.

Serological biomarkers detect active joint destruction and inflammation in patients with haemophilic arthropathy.

Hua B, Olsen EHN, Sun S, Gudme CN, Wang L, Vandahl B, Roepstorff K, Kjelgaard-Hansen M, Sørensen BB, Zhao Y, Karsdal MA, Manon-Jensen T.

Haemophilia. 2017 Jul;23(4):e294-e300. doi: 10.1111/hae.13196. Epub 2017 Apr 24.

PMID:
28439941
11.

Measurement of serum C-reactive protein concentration for discriminating between suppurative arthritis and osteoarthritis in dogs.

Hillström A, Bylin J, Hagman R, Björhall K, Tvedten H, Königsson K, Fall T, Kjelgaard-Hansen M.

BMC Vet Res. 2016 Oct 28;12(1):240.

12.

Altered collagen turnover in factor VIII-deficient rats with hemophilic arthropathy identifies potential novel serological biomarkers in hemophilia.

Manon-Jensen T, Karsdal MA, Nielsen LN, Kjelgaard-Hansen M, Vandahl B, Olsen EH, Enoksson M, Roepstorff K.

J Thromb Haemost. 2016 Dec;14(12):2419-2429. doi: 10.1111/jth.13518. Epub 2016 Oct 28.

13.

Acute phase proteins in dogs naturally infected with the Giant Kidney Worm (Dioctophyme renale).

Schmidt EM, Kjelgaard-Hansen M, Thomas F, Tvarijonaviciute A, Cerón JJ, Eckersall PD.

Vet Clin Pathol. 2016 Dec;45(4):657-664. doi: 10.1111/vcp.12400. Epub 2016 Oct 17. Erratum in: Vet Clin Pathol. 2017 Jun;46(2):380.

PMID:
27748965
14.

Visualization of haemophilic arthropathy in F8-/- rats by ultrasonography and micro-computed tomography.

Christensen KR, Roepstorff K, Petersen M, Wiinberg B, Hansen AK, Kjelgaard-Hansen M, Nielsen LN.

Haemophilia. 2017 Jan;23(1):152-162. doi: 10.1111/hae.13080. Epub 2016 Sep 9.

PMID:
27611596
15.

Acute-phase proteins as diagnostic markers in horses with colic.

Pihl TH, Scheepers E, Sanz M, Goddard A, Page P, Toft N, Kjelgaard-Hansen M, Andersen PH, Jacobsen S.

J Vet Emerg Crit Care (San Antonio). 2016 Sep;26(5):664-74. doi: 10.1111/vec.12504. Epub 2016 Jul 6.

PMID:
27384962
16.

Cardiac troponin I in three cat breeds with hypertrophic cardiomyopathy.

Langhorn R, Willesen JL, Tarnow I, Kjelgaard-Hansen M, Koch J.

Vet Rec. 2016 May 21;178(21):532. doi: 10.1136/vr.103549. Epub 2016 Apr 13. No abstract available.

PMID:
27076529
17.

The F8(-/-) rat as a model of hemophilic arthropathy.

Sørensen KR, Roepstorff K, Wiinberg B, Hansen AK, Tranholm M, Nielsen LN, Kjelgaard-Hansen M.

J Thromb Haemost. 2016 Jun;14(6):1216-25. doi: 10.1111/jth.13328. Epub 2016 May 10.

18.

Excessive Pro-Inflammatory Serum Cytokine Concentrations in Virulent Canine Babesiosis.

Goddard A, Leisewitz AL, Kjelgaard-Hansen M, Kristensen AT, Schoeman JP.

PLoS One. 2016 Mar 8;11(3):e0150113. doi: 10.1371/journal.pone.0150113. eCollection 2016.

19.

Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

Olsen HG, Kjelgaard-Hansen M, Tveden-Nyborg P, Birck MM, Hammelev KP, Vegge A, Aalbæk B, Leifsson PS, Jensen HE, Iburg T, Heegaard PM, Nielsen OL.

BMC Res Notes. 2016 Feb 16;9:99. doi: 10.1186/s13104-016-1888-7.

20.

C-reactive protein: quantitative marker of surgical trauma and post-surgical complications in dogs: a systematic review.

Christensen MB, Eriksen T, Kjelgaard-Hansen M.

Acta Vet Scand. 2015 Oct 20;57:71. doi: 10.1186/s13028-015-0164-5. Review.

21.

Validation and application of a canine-specific automated high-sensitivity C-reactive protein assay.

Hillström A, Hagman R, Söder J, Häggström J, Ljungvall I, Kjelgaard-Hansen M.

J Vet Diagn Invest. 2015 Mar;27(2):182-90. doi: 10.1177/1040638715575751.

PMID:
25776543
22.

Serum protein capillary electrophoresis and measurement of acute phase proteins in a captive cheetah (Acinonyx jubatus) population.

Depauw S, Delanghe J, Whitehouse-Tedd K, Kjelgaard-Hansen M, Christensen M, Hesta M, Tugirimana P, Budd J, Dermauw V, Janssens GP.

J Zoo Wildl Med. 2014 Sep;45(3):497-506.

PMID:
25314816
23.

Expression of acute phase proteins and inflammatory cytokines in mouse mammary gland following Staphylococcus aureus challenge and in response to milk accumulation.

Nazemi S, Aalbæk B, Kjelgaard-Hansen M, Safayi S, Klærke DA, Knight CH.

J Dairy Res. 2014 Nov;81(4):445-54. doi: 10.1017/S0022029914000454. Epub 2014 Sep 17.

PMID:
25230141
24.

Cardiac troponin I and T as prognostic markers in cats with hypertrophic cardiomyopathy.

Langhorn R, Tarnow I, Willesen JL, Kjelgaard-Hansen M, Skovgaard IM, Koch J.

J Vet Intern Med. 2014 Sep-Oct;28(5):1485-91. doi: 10.1111/jvim.12407. Epub 2014 Jul 23.

25.

Prediction of long-term outcome by measurement of serum concentration of cardiac troponins in critically ill dogs with systemic inflammation.

Langhorn R, Thawley V, Oyama MA, King LG, Machen MC, Trafny DJ, Willesen JL, Tarnow I, Kjelgaard-Hansen M.

J Vet Intern Med. 2014 Sep-Oct;28(5):1492-7. doi: 10.1111/jvim.12402. Epub 2014 Jul 16.

26.

Inflammation-induced haemostatic response in layer chickens infected with Streptococcus equi subsp. zooepidemicus as evaluated by fibrinogen, prothrombin time and thromboelastography.

Roy K, Bertelsen MF, Pors SE, Johansen KW, Kristensen AT, Kjelgaard-Hansen M, Andreasen EB, Christensen JP, Biswas PK, Bojesen AM.

Avian Pathol. 2014;43(4):364-70. doi: 10.1080/03079457.2014.938608. Epub 2014 Jul 21.

PMID:
25017320
27.

Acute-phase responses in healthy and diseased rhesus macaques (Macaca mulatta).

Krogh AK, Lundsgaard JF, Bakker J, Langermans JA, Verreck FA, Kjelgaard-Hansen M, Jacobsen S, Bertelsen MF.

J Zoo Wildl Med. 2014 Jun;45(2):306-14.

PMID:
25000691
28.

Validation of a commercially available automated canine-specific immunoturbidimetric method for measuring canine C-reactive protein.

Hillström A, Hagman R, Tvedten H, Kjelgaard-Hansen M.

Vet Clin Pathol. 2014 Jun;43(2):235-43. doi: 10.1111/vcp.12150. Epub 2014 May 5.

29.

Combined assessment of serum free and total T4 in a general clinical setting seemingly has limited potential in improving diagnostic accuracy of thyroid dysfunction in dogs and cats.

Rasmussen SH, Andersen HH, Kjelgaard-Hansen M.

Vet Clin Pathol. 2014 Mar;43(1):1-3. doi: 10.1111/vcp.12106. No abstract available.

PMID:
24588571
30.

Exercise induced hypercoagulability, increased von Willebrand factor and decreased thyroid hormone concentrations in sled dogs.

Krogh AK, Legind P, Kjelgaard-Hansen M, Bochsen L, Kristensen AT.

Acta Vet Scand. 2014 Feb 7;56:11. doi: 10.1186/1751-0147-56-11.

31.

Comparison of serum amyloid A and C-reactive protein as diagnostic markers of systemic inflammation in dogs.

Christensen MB, Langhorn R, Goddard A, Andreasen EB, Moldal E, Tvarijonaviciute A, Kirpensteijn J, Jakobsen S, Persson F, Kjelgaard-Hansen M.

Can Vet J. 2014 Feb;55(2):161-8.

32.

Performance of a commercial Chicken-Ovo-transferrin-ELISA on the serum of brown layer chickens infected with Gallibacterium anatis and Streptococcus zooepidemicus.

Roy K, Kjelgaard-Hansen M, Pors SE, Christensen JP, Biswas PK, Bojesen AM.

Avian Pathol. 2014;43(1):57-61. doi: 10.1080/03079457.2013.867011. Epub 2014 Jan 6.

PMID:
24313352
33.

Myocardial injury in dogs with snake envenomation and its relation to systemic inflammation.

Langhorn R, Persson F, Ablad B, Goddard A, Schoeman JP, Willesen JL, Tarnow I, Kjelgaard-Hansen M.

J Vet Emerg Crit Care (San Antonio). 2014 Mar-Apr;24(2):174-81. doi: 10.1111/vec.12127. Epub 2013 Dec 4.

PMID:
24304906
34.

Evaluation of a high-sensitivity assay for measurement of canine and feline serum cardiac troponin I.

Langhorn R, Willesen JL, Tarnow I, Kjelgaard-Hansen M.

Vet Clin Pathol. 2013 Dec;42(4):490-8. doi: 10.1111/vcp.12085. Epub 2013 Oct 16.

PMID:
24131244
35.

Comparison of components of biological variation between 3 equine thromboelastography assays.

Hyldahl Laursen S, Andersen PH, Kjelgaard-Hansen M, Wiinberg B.

Vet Clin Pathol. 2013 Dec;42(4):443-50. doi: 10.1111/vcp.12079. Epub 2013 Sep 18.

PMID:
24102554
36.

Monocyte chemotactic protein-1 and other inflammatory parameters in Bernese Mountain dogs with disseminated histiocytic sarcoma.

Nikolic Nielsen L, Kjelgaard-Hansen M, Kristensen AT.

Vet J. 2013 Nov;198(2):424-8. doi: 10.1016/j.tvjl.2013.07.030. Epub 2013 Aug 27.

PMID:
23992872
37.

Serum paraoxonase 1 activity in dogs: preanalytical and analytical factors and correlation with C-reactive protein and alpha-2-globulin.

Rossi G, Giordano A, Pezzia F, Kjelgaard-Hansen M, Paltrinieri S.

Vet Clin Pathol. 2013 Sep;42(3):329-41. doi: 10.1111/vcp.12073. Epub 2013 Aug 14.

PMID:
23944371
38.

Canine serum C-reactive protein as a quantitative marker of the inflammatory stimulus of aseptic elective soft tissue surgery.

Kjelgaard-Hansen M, Strom H, Mikkelsen LF, Eriksen T, Jensen AL, Luntang-Jensen M.

Vet Clin Pathol. 2013 Sep;42(3):342-5. doi: 10.1111/vcp.12063. Epub 2013 Jul 30.

PMID:
23899087
39.

Evaluation of the use of serum C-reactive protein concentration to predict outcome in puppies infected with canine parvovirus.

McClure V, van Schoor M, Thompson PN, Kjelgaard-Hansen M, Goddard A.

J Am Vet Med Assoc. 2013 Aug 1;243(3):361-6. doi: 10.2460/javma.243.3.361.

PMID:
23865878
40.

Prognostic importance of myocardial injury in critically ill dogs with systemic inflammation.

Langhorn R, Oyama MA, King LG, Machen MC, Trafny DJ, Thawley V, Willesen JL, Tarnow I, Kjelgaard-Hansen M.

J Vet Intern Med. 2013 Jul-Aug;27(4):895-903. doi: 10.1111/jvim.12105. Epub 2013 May 16.

41.

Investigation of the solubility and the potentials for purification of serum amyloid A (SAA) from equine acute phase serum--a pilot study.

Christensen MB, Sørensen JC, Jacobsen S, Kjelgaard-Hansen M.

BMC Res Notes. 2013 Apr 16;6:152. doi: 10.1186/1756-0500-6-152.

42.

Serum amyloid A and haptoglobin concentrations in serum and peritoneal fluid of healthy horses and horses with acute abdominal pain.

Pihl TH, Andersen PH, Kjelgaard-Hansen M, Mørck NB, Jacobsen S.

Vet Clin Pathol. 2013 Jun;42(2):177-83. doi: 10.1111/vcp.12031. Epub 2013 Apr 11.

PMID:
23577834
43.

Organohalogen contaminants and Blood plasma clinical-chemical parameters in three colonies of North Atlantic Great skua (Stercorarius skua).

Sonne C, Rigét FF, Leat EH, Bourgeon S, Borgå K, Strøm H, Hanssen SA, Gabrielsen GW, Petersen A, Olafsdottir K, Magnusdottir E, Bustnes JO, Furness RW, Kjelgaard-Hansen M.

Ecotoxicol Environ Saf. 2013 Jun;92:245-51. doi: 10.1016/j.ecoenv.2013.02.012. Epub 2013 Mar 26.

PMID:
23537726
44.

Canine serum amyloid A (SAA) measured by automated latex agglutination turbidimetry is useful for routine sensitive and specific detection of systemic inflammation in a general clinical setting.

Christensen MB, Langhorn R, Goddard A, Andreasen EB, Moldal E, Tvarijonaviciute A, Kirpenteijn J, Jakobsen S, Persson F, Kjelgaard-Hansen M.

J Vet Med Sci. 2013 May 2;75(4):459-66. Epub 2012 Nov 28.

45.

Hemostatic abnormalities in uncomplicated babesiosis (Babesia rossi) in dogs.

Liebenberg C, Goddard A, Wiinberg B, Kjelgaard-Hansen M, van der Merwe LL, Thompson PN, Matjila PT, Schoeman JP.

J Vet Intern Med. 2013 Jan-Feb;27(1):150-6. doi: 10.1111/jvim.12016. Epub 2012 Nov 29.

46.

Mortality in virulent canine babesiosis is associated with a consumptive coagulopathy.

Goddard A, Wiinberg B, Schoeman JP, Kristensen AT, Kjelgaard-Hansen M.

Vet J. 2013 May;196(2):213-7. doi: 10.1016/j.tvjl.2012.09.009. Epub 2012 Oct 23.

PMID:
23098634
47.

The use of sequential organ failure assessment parameters in an awake porcine model of severe Staphylococcus aureus sepsis.

Soerensen KE, Nielsen OL, Birck MM, Soerensen DB, Leifsson PS, Jensen HE, Aalbaek B, Kristensen AT, Wiinberg B, Kjelgaard-Hansen M, Heegaard PM, Iburg TM.

APMIS. 2012 Nov;120(11):909-21. doi: 10.1111/j.1600-0463.2012.02917.x. Epub 2012 May 15.

PMID:
23009115
48.

Plasma IL-8 concentrations are increased in dogs with spirocercosis.

Dvir E, Mellanby RJ, Kjelgaard-Hansen M, Schoeman JP.

Vet Parasitol. 2012 Nov 23;190(1-2):185-90. doi: 10.1016/j.vetpar.2012.06.007. Epub 2012 Jun 17.

PMID:
22770706
49.

Evaluation of an automated assay based on monoclonal anti-human serum amyloid A (SAA) antibodies for measurement of canine, feline, and equine SAA.

Christensen M, Jacobsen S, Ichiyanagi T, Kjelgaard-Hansen M.

Vet J. 2012 Dec;194(3):332-7. doi: 10.1016/j.tvjl.2012.05.007. Epub 2012 Jun 15.

PMID:
22704135
50.

The impact of Staphylococcus aureus concentration on the development of pulmonary lesions and cytokine expression after intravenous inoculation of pigs.

Soerensen KE, Skovgaard K, Heegaard PM, Jensen HE, Nielsen OL, Leifsson PS, Olsen HG, Aalbaek B, Kristensen AT, Kjelgaard-Hansen M, Wiinberg B, Iburg TM.

Vet Pathol. 2012 Nov;49(6):950-62. doi: 10.1177/0300985812439726. Epub 2012 Mar 28.

PMID:
22461225

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