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Jeopardized myocardium and survival in patients presenting to the catheterization laboratory with ST-elevation myocardial infarction and shock.

Joshi FR, Pedersen F, Räder S, Raunsø J, Kjaergaard J, Lindholm M, Hassager C, Engstrøm T, Holmvang L, Helqvist S, Jørgensen E.

Cardiovasc Revasc Med. 2019 Nov 9. pii: S1553-8389(19)30745-6. doi: 10.1016/j.carrev.2019.11.002. [Epub ahead of print]


Corrigendum to "Highly malignant routine EEG predicts poor prognosis after cardiac arrest in the Target Temperature Management trial" [Resuscitation 131 (2019) 24-28].

Backman S, Cronberg T, Friberg H, Ullén S, Horn J, Kjaergaard J, Hassager C, Wanscher M, Nielsen N, Westhall E.

Resuscitation. 2019 Dec;145:82. doi: 10.1016/j.resuscitation.2019.10.023. Epub 2019 Nov 11. No abstract available.


"Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA): Safety and efficacy of low-dose Iloprost, a prostacyclin analogue, in addition to standard therapy, as compared to standard therapy alone, in post-cardiac-arrest-syndrome patients."

Meyer ASP, Johansson PI, Kjaergaard J, Frydland M, Meyer MAS, Henriksen HH, Thomsen JH, Wiberg SC, Hassager C, Ostrowski SR.

Am Heart J. 2019 Oct 21;219:9-20. doi: 10.1016/j.ahj.2019.10.002. [Epub ahead of print]


A caspase-6-cleaved fragment of Glial Fibrillary Acidic Protein as a potential serological biomarker of CNS injury after cardiac arrest.

Jonesco DS, Hassager C, Frydland M, Kjærgaard J, Karsdal M, Henriksen K.

PLoS One. 2019 Nov 6;14(11):e0224633. doi: 10.1371/journal.pone.0224633. eCollection 2019.


Diagnosis and treatment of acute respiratory illness in children under five in primary care in low-, middle-, and high-income countries: A descriptive FRESH AIR study.

Kjærgaard J, Anastasaki M, Stubbe Østergaard M, Isaeva E, Akylbekov A, Nguyen NQ, Reventlow S, Lionis C, Sooronbaev T, Pham LA, Nantanda R, Stout JW, Poulsen A; FRESH AIR Collaborators.

PLoS One. 2019 Nov 6;14(11):e0221389. doi: 10.1371/journal.pone.0221389. eCollection 2019.


Vector Flow Imaging of the Ascending Aorta in Patients with Tricuspid and Bicuspid Aortic Valve Stenosis Treated with Biological and Mechanical Implants.

Hansen KL, Møller-Sørensen H, Kjaergaard J, Jensen JA, Nielsen MB.

Ultrasound Med Biol. 2020 Jan;46(1):64-72. doi: 10.1016/j.ultrasmedbio.2019.09.020. Epub 2019 Oct 31.


Infectious diseases detected by screening after arrival to Denmark in internationally adopted children.

Nielsen AV, Kjaergaard J, Pedersen TM, Helmuth IG, Nygaard U, Nielsen HW, Christensen VB, Kurtzhals JAL, Poulsen A.

Acta Paediatr. 2019 Oct 3. doi: 10.1111/apa.15045. [Epub ahead of print]


The complement lectin pathway protein MAp19 and out-of-hospital cardiac arrest: Insights from two randomized clinical trials.

Bro-Jeppesen J, Jeppesen AN, Haugaard S, Troldborg A, Hassager C, Kjaergaard J, Kirkegaard H, Wanscher M, Hvas AM, Thiel S.

Eur Heart J Acute Cardiovasc Care. 2019 Sep 20:2048872619870031. doi: 10.1177/2048872619870031. [Epub ahead of print]


Mechanical circulatory support for decompensated heart failure: the last remaining indication for intra-aortic balloon pump?

Kjaergaard J, Møller JE, Hassager C.

EuroIntervention. 2019 Sep 20;15(7):571-573. doi: 10.4244/EIJV15I7A104. No abstract available.


Cardiac output during targeted temperature management and renal function after out-of-hospital cardiac arrest.

Grand J, Bro-Jeppesen J, Hassager C, Rundgren M, Winther-Jensen M, Thomsen JH, Nielsen N, Wanscher M, Kjærgaard J.

J Crit Care. 2019 Dec;54:65-73. doi: 10.1016/j.jcrc.2019.07.013. Epub 2019 Jul 15.


Cardiac output, heart rate and stroke volume during targeted temperature management after out-of-hospital cardiac arrest: Association with mortality and cause of death.

Grand J, Kjaergaard J, Bro-Jeppesen J, Wanscher M, Nielsen N, Lindholm MG, Thomsen JH, Boesgaard S, Hassager C.

Resuscitation. 2019 Sep;142:136-143. doi: 10.1016/j.resuscitation.2019.07.024. Epub 2019 Jul 27.


Arterial blood pressure during targeted temperature management after out-of-hospital cardiac arrest and association with brain injury and long-term cognitive function.

Grand J, Lilja G, Kjaergaard J, Bro-Jeppesen J, Friberg H, Wanscher M, Cronberg T, Nielsen N, Hassager C.

Eur Heart J Acute Cardiovasc Care. 2019 Jun 27:2048872619860804. doi: 10.1177/2048872619860804. [Epub ahead of print]


Design paper of the "Blood pressure targets in post-resuscitation care and bedside monitoring of cerebral energy state: a randomized clinical trial".

Mölström S, Nielsen TH, Nordström CH, Hassager C, Møller JE, Kjærgaard J, Möller S, Schmidt H, Toft P.

Trials. 2019 Jun 10;20(1):344. doi: 10.1186/s13063-019-3397-1.


Admission Leukocyte Count is Associated with Late Cardiogenic Shock Development and All-Cause 30-Day Mortality in Patients with St-Elevation Myocardial Infarction.

Klein A, Wiberg S, Hassager C, Winther-Jensen M, Frikke-Schmidt R, Bang LE, Lindholm MG, Holmvang L, Moeller-Helgestad O, Ravn HB, Jensen LO, Kjaergaard J, Moeller JE, Frydland M.

Shock. 2019 May 1. doi: 10.1097/SHK.0000000000001369. [Epub ahead of print]


Serum tau fragments as predictors of death or poor neurological outcome after out-of-hospital cardiac arrest.

Grand J, Kjaergaard J, Nielsen N, Friberg H, Cronberg T, Bro-Jeppesen J, Karsdal MA, Nielsen HB, Frydland M, Henriksen K, Mattsson N, Zetterberg H, Hassager C.

Biomarkers. 2019 Sep;24(6):584-591. doi: 10.1080/1354750X.2019.1609580. Epub 2019 May 31.


Prognostic value of automated pupillometry: an unselected cohort from a cardiac intensive care unit.

Obling L, Hassager C, Illum C, Grand J, Wiberg S, Lindholm MG, Winther-Jensen M, Kondziella D, Kjaergaard J.

Eur Heart J Acute Cardiovasc Care. 2019 Apr 5:2048872619842004. doi: 10.1177/2048872619842004. [Epub ahead of print]


Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest.

Wiberg S, Stride N, Bro-Jeppesen J, Holmberg MJ, Kjærgaard J, Larsen S, Donnino MW, Hassager C, Dela F.

Eur Heart J Acute Cardiovasc Care. 2019 Mar 11:2048872618814700. doi: 10.1177/2048872618814700. [Epub ahead of print]


Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest: an analysis of the TTH48 trial.

De Fazio C, Skrifvars MB, Søreide E, Creteur J, Grejs AM, Kjærgaard J, Laitio T, Nee J, Kirkegaard H, Taccone FS.

Crit Care. 2019 Feb 22;23(1):61. doi: 10.1186/s13054-019-2335-7.


Associations between partial pressure of oxygen and neurological outcome in out-of-hospital cardiac arrest patients: an explorative analysis of a randomized trial.

Ebner F, Ullén S, Åneman A, Cronberg T, Mattsson N, Friberg H, Hassager C, Kjærgaard J, Kuiper M, Pelosi P, Undén J, Wise MP, Wetterslev J, Nielsen N.

Crit Care. 2019 Jan 28;23(1):30. doi: 10.1186/s13054-019-2322-z.


Mean arterial pressure during targeted temperature management and renal function after out-of-hospital cardiac arrest.

Grand J, Hassager C, Winther-Jensen M, Rundgren M, Friberg H, Horn J, Wise MP, Nielsen N, Kuiper M, Wiberg S, Thomsen JH, Jaeger Wanscher MC, Frydland M, Kjaergaard J.

J Crit Care. 2019 Apr;50:234-241. doi: 10.1016/j.jcrc.2018.12.009. Epub 2018 Dec 18.


Tricuspid annular plane systolic excursion is significantly reduced during uncomplicated coronary artery bypass surgery: A prospective observational study.

Korshin A, Grønlykke L, Nilsson JC, Møller-Sørensen H, Ihlemann N, Kjøller SM, Damgaard S, Lehnert P, Hassager C, Kjaergaard J, Ravn HB.

J Thorac Cardiovasc Surg. 2019 Aug;158(2):480-489. doi: 10.1016/j.jtcvs.2018.09.114. Epub 2018 Oct 17.


Out-of-hospital cardiac arrest at place of residence is associated with worse outcomes in patients admitted to intensive care. A post-hoc analysis of the targeted temperature management trial.

Andréll C, Dankiewicz J, Hassager C, Horn J, Kjærgaard J, Winther-Jensen M, Wise MP, Nielsen N, Stammet P, Friberg H; TTM Trial Investigators.

Minerva Anestesiol. 2019 Jul;85(7):738-745. doi: 10.23736/S0375-9393.18.12878-1. Epub 2018 Nov 22.


Influence of Strategic Cortical Infarctions on Pupillary Function.

Peinkhofer C, Martens P, Grand J, Truelsen T, Knudsen GM, Kjaergaard J, Kondziella D.

Front Neurol. 2018 Oct 29;9:916. doi: 10.3389/fneur.2018.00916. eCollection 2018.


Detailed analysis of health-related quality of life after out-of-hospital cardiac arrest.

Bohm M, Lilja G, Finnbogadóttir H, Cronberg T, Undén J, Friberg H, Kjærgaard J, Nielsen N, Wise MP, Åkerman E.

Resuscitation. 2019 Feb;135:197-204. doi: 10.1016/j.resuscitation.2018.10.028. Epub 2018 Oct 29.


Serum Neurofilament Light Chain for Prognosis of Outcome After Cardiac Arrest.

Moseby-Knappe M, Mattsson N, Nielsen N, Zetterberg H, Blennow K, Dankiewicz J, Dragancea I, Friberg H, Lilja G, Insel PS, Rylander C, Westhall E, Kjaergaard J, Wise MP, Hassager C, Kuiper MA, Stammet P, Wanscher MCJ, Wetterslev J, Erlinge D, Horn J, Pellis T, Cronberg T.

JAMA Neurol. 2019 Jan 1;76(1):64-71. doi: 10.1001/jamaneurol.2018.3223.


Otoacoustic Emissions for Outcome Prediction in Postanoxic Brain Injury.

Kondziella D, Jensen AM, Hjuler T, Bille M, Kjaergaard J.

Front Neurol. 2018 Sep 25;9:796. doi: 10.3389/fneur.2018.00796. eCollection 2018.


Lactate is a Prognostic Factor in Patients Admitted With Suspected ST-Elevation Myocardial Infarction.

Frydland M, Møller JE, Wiberg S, Lindholm MG, Hansen R, Henriques JPS, Møller-Helgestad OK, Bang LE, Frikke-Schmidt R, Goetze JP, Udesen NLJ, Thomsen JH, Ouweneel DM, Obling L, Ravn HB, Holmvang L, Jensen LO, Kjaergaard J, Hassager C.

Shock. 2019 Mar;51(3):321-327. doi: 10.1097/SHK.0000000000001191.


Refractory out-of-hospital cardiac arrest with ongoing cardiopulmonary resuscitation at hospital arrival - survival and neurological outcome without extracorporeal cardiopulmonary resuscitation.

Gregers E, Kjærgaard J, Lippert F, Thomsen JH, Køber L, Wanscher M, Hassager C, Søholm H.

Crit Care. 2018 Sep 29;22(1):242. doi: 10.1186/s13054-018-2176-9.


Use of renal replacement therapy after out-of-hospital cardiac arrest in Denmark 2005-2013.

Winther-Jensen M, Kjaergaard J, Lassen JF, Køber L, Torp-Pedersen C, Hansen SM, Lippert F, Kragholm K, Christensen EF, Hassager C.

Scand Cardiovasc J. 2018 Oct;52(5):238-243. doi: 10.1080/14017431.2018.1503707. Epub 2018 Sep 5.


Carbon dioxide dynamics in relation to neurological outcome in resuscitated out-of-hospital cardiac arrest patients: an exploratory Target Temperature Management Trial substudy.

Ebner F, Harmon MBA, Aneman A, Cronberg T, Friberg H, Hassager C, Juffermans N, Kjærgaard J, Kuiper M, Mattsson N, Pelosi P, Ullén S, Undén J, Wise MP, Nielsen N.

Crit Care. 2018 Aug 18;22(1):196. doi: 10.1186/s13054-018-2119-5.


Cancer is not associated with higher short or long-term mortality after successful resuscitation from out-of-hospital cardiac arrest when adjusting for prognostic factors.

Winther-Jensen M, Kjaergaard J, Hassager C, Køber L, Lippert F, Søholm H.

Eur Heart J Acute Cardiovasc Care. 2018 Aug 10:2048872618794090. doi: 10.1177/2048872618794090. [Epub ahead of print]


Highly malignant routine EEG predicts poor prognosis after cardiac arrest in the Target Temperature Management trial.

Backman S, Cronberg T, Friberg H, Ullén S, Horn J, Kjaergaard J, Hassager C, Wanscher M, Nielsen N, Westhall E.

Resuscitation. 2018 Oct;131:24-28. doi: 10.1016/j.resuscitation.2018.07.024. Epub 2018 Jul 24. Erratum in: Resuscitation. 2019 Dec;145:82.


The association between plasma miR-122-5p release pattern at admission and all-cause mortality or shock after out-of-hospital cardiac arrest.

Gilje P, Frydland M, Bro-Jeppesen J, Dankiewicz J, Friberg H, Rundgren M, Devaux Y, Stammet P, Al-Mashat M, Jögi J, Kjaergaard J, Hassager C, Erlinge D.

Biomarkers. 2019 Feb;24(1):29-35. doi: 10.1080/1354750X.2018.1499804. Epub 2018 Aug 23.


Validation and Clinical Evaluation of a Method for Double-Blinded Blood Pressure Target Investigation in Intensive Care Medicine.

Grand J, Meyer ASP, Hassager C, Schmidt H, Møller JE, Kjaergaard J.

Crit Care Med. 2018 Oct;46(10):1626-1633. doi: 10.1097/CCM.0000000000003289.


Author Correction: Recurrent lower respiratory illnesses among young children in rural Kyrgyzstan: overuse of antibiotics and possible under-diagnosis of asthma. A qualitative FRESH AIR study.

Østergaard MS, Kjærgaard J, Kristensen MM, Reventlow S, Poulsen A, Isaeva E, Akylbekov A, Sooronbaev T.

NPJ Prim Care Respir Med. 2018 Jun 28;28(1):25. doi: 10.1038/s41533-018-0082-x.


Neurological prognostication tools in out-of-hospital cardiac arrest patients in Danish intensive care units from 2005 to 2013.

Winther-Jensen M, Hassager C, Lassen JF, Køber L, Torp-Pedersen C, Hansen SM, Lippert F, Kragholm K, Christensen EF, Kjaergaard J.

Acta Anaesthesiol Scand. 2018 Nov;62(10):1412-1420. doi: 10.1111/aas.13177. Epub 2018 Jun 26.


Time to epileptiform activity and EEG background recovery are independent predictors after cardiac arrest.

Westhall E, Rosén I, Rundgren M, Bro-Jeppesen J, Kjaergaard J, Hassager C, Lindehammar H, Horn J, Ullén S, Nielsen N, Friberg H, Cronberg T.

Clin Neurophysiol. 2018 Aug;129(8):1660-1668. doi: 10.1016/j.clinph.2018.05.016. Epub 2018 Jun 9.


Lactate, lactate clearance and outcome after cardiac arrest: A post-hoc analysis of the TTM-Trial.

Düring J, Dankiewicz J, Cronberg T, Hassager C, Hovdenes J, Kjaergaard J, Kuiper M, Nielsen N, Pellis T, Stammet P, Vulto J, Wanscher M, Wise M, Åneman A, Friberg H.

Acta Anaesthesiol Scand. 2018 Nov;62(10):1436-1442. doi: 10.1111/aas.13172. Epub 2018 Jun 21.


A2A Adenosine Receptor Gene Deletion or Synthetic A2A Antagonist Liberate Tumor-Reactive CD8+ T Cells from Tumor-Induced Immunosuppression.

Kjaergaard J, Hatfield S, Jones G, Ohta A, Sitkovsky M.

J Immunol. 2018 Jul 15;201(2):782-791. doi: 10.4049/jimmunol.1700850. Epub 2018 May 25.


Osborn waves following out-of-hospital cardiac arrest-Effect of level of temperature management and risk of arrhythmia and death.

Hadziselimovic E, Thomsen JH, Kjaergaard J, Køber L, Graff C, Pehrson S, Nielsen N, Erlinge D, Frydland M, Wiberg S, Hassager C.

Resuscitation. 2018 Jul;128:119-125. doi: 10.1016/j.resuscitation.2018.04.037. Epub 2018 May 1.


Recurrent lower respiratory illnesses among young children in rural Kyrgyzstan: overuse of antibiotics and possible under-diagnosis of asthma. A qualitative FRESH AIR study.

Østergaard MS, Kjærgaard J, Kristensen MM, Reventlow S, Poulsen A, Isaeva E, Akylbekov A, Sooronbaev T.

NPJ Prim Care Respir Med. 2018 Apr 10;28(1):13. doi: 10.1038/s41533-018-0081-y. Erratum in: NPJ Prim Care Respir Med. 2018 Jun 28;28(1):25.


BCG Vaccination at Birth and Rate of Hospitalization for Infection Until 15 Months of Age in Danish Children: A Randomized Clinical Multicenter Trial.

Stensballe LG, Ravn H, Birk NM, Kjærgaard J, Nissen TN, Pihl GT, Thøstesen LM, Greisen G, Jeppesen DL, Kofoed PE, Pryds O, Sørup S, Aaby P, Benn CS.

J Pediatric Infect Dis Soc. 2019 Jul 1;8(3):213-220. doi: 10.1093/jpids/piy029.


Importance of comorbidities in comatose survivors of shockable and non-shockable out-of-hospital cardiac arrest treated with target temperature management.

Salam I, Thomsen JH, Kjaergaard J, Bro-Jeppesen J, Frydland M, Winther-Jensen M, Køber L, Wanscher M, Hassager C, Søholm H.

Scand Cardiovasc J. 2018 Jun;52(3):133-140. doi: 10.1080/14017431.2018.1450991. Epub 2018 Mar 19.


Plasma Concentration of Biomarkers Reflecting Endothelial Cell- and Glycocalyx Damage are Increased in Patients With Suspected ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock.

Frydland M, Ostrowski SR, Møller JE, Hadziselimovic E, Holmvang L, Ravn HB, Jensen LO, Pettersson AS, Kjaergaard J, Lindholm MG, Johansson PI, Hassager C.

Shock. 2018 Nov;50(5):538-544. doi: 10.1097/SHK.0000000000001123.


[Advanced life support for cardiac arrest beyond the algorithm].

Rudolph SS, Isbye DL, Pfeiffer P, Kjærgaard J.

Ugeskr Laeger. 2018 Jan 29;180(5). pii: V05170386. Review. Danish.


In response to: phenylephrine and paradoxically increased muscle tissue oxygenation: is the mechanism related to local venoconstriction or augmented venous return?

Sørensen H, Egesborg AH, Thomsen JH, Meyer ASP, Terzic D, Hilsted L, Kjærgaard J, Goetze JP, Barbosa TC, Secher NH.

J Clin Monit Comput. 2018 Dec;32(6):1145-1146. doi: 10.1007/s10877-018-0108-5. Epub 2018 Jan 31. No abstract available.


The feasibility of tricuspid annular plane systolic excursion performed by transesophageal echocardiography throughout heart surgery and its interchangeability with transthoracic echocardiography.

Korshin A, Grønlykke L, Nilsson JC, Møller-Sørensen H, Ihlemann N, Kjøller M, Damgaard S, Lehnert P, Hassager C, Kjaergaard J, Ravn HB.

Int J Cardiovasc Imaging. 2018 Jul;34(7):1017-1028. doi: 10.1007/s10554-018-1306-4. Epub 2018 Jan 30.


Time to awakening after cardiac arrest and the association with target temperature management.

Lybeck A, Cronberg T, Aneman A, Hassager C, Horn J, Hovdenes J, Kjærgaard J, Kuiper M, Wanscher M, Stammet P, Wise MP, Nielsen N, Ullén S, Friberg H; TTM-trial investigators.

Resuscitation. 2018 May;126:166-171. doi: 10.1016/j.resuscitation.2018.01.027.


Mothers' informational needs when deciding to have their newborn infant vaccinated with BCG. A Mixed-methods design.

Pihl GT, Ammentorp J, Johannessen H, Kjaergaard J, Nissen TN, Birk NM, Stensballe LG, Thøstesen LM, Kofoed PE.

Scand J Caring Sci. 2018 Sep;32(3):1118-1126. doi: 10.1111/scs.12557. Epub 2018 Jan 25.


Return to Work and Participation in Society After Out-of-Hospital Cardiac Arrest.

Lilja G, Nielsen N, Bro-Jeppesen J, Dunford H, Friberg H, Hofgren C, Horn J, Insorsi A, Kjaergaard J, Nilsson F, Pelosi P, Winters T, Wise MP, Cronberg T.

Circ Cardiovasc Qual Outcomes. 2018 Jan;11(1):e003566. doi: 10.1161/CIRCOUTCOMES.117.003566.


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