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Preserved capacity for satellite cell proliferation, regeneration, and hypertrophy in the skeletal muscle of healthy elderly men.

Karlsen A, Soendenbroe C, Malmgaard-Clausen NM, Wagener F, Moeller CE, Senhaji Z, Damberg K, Andersen JL, Schjerling P, Kjaer M, Mackey AL.

FASEB J. 2020 Mar 13. doi: 10.1096/fj.202000196R. [Epub ahead of print]


Regional collagen turnover and composition of the human patellar tendon.

Zhang C, Couppé C, Scheijen JLJM, Schalkwijk CG, Kjaer M, Magnusson SP, Svensson RB.

J Appl Physiol (1985). 2020 Mar 12. doi: 10.1152/japplphysiol.00030.2020. [Epub ahead of print]


Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon.

Bayer ML, Svensson RB, Schjerling P, Williams AS, Wasserman DH, Kjaer M.

Cell Tissue Res. 2020 Feb 28. doi: 10.1007/s00441-020-03184-y. [Epub ahead of print]


Strategies to develop a prophylaxis for the prevention of HPA-1a immunization and fetal and neonatal alloimmune thrombocytopenia.

Kjær M, Geisen C, Akkök ÇA, Wikman A, Sachs U, Bussel JB, Nielsen K, Walles K, Curtis BR, Vidarsson G, Järås K, Skogen B.

Transfus Apher Sci. 2020 Feb;59(1):102712. doi: 10.1016/j.transci.2019.102712. Epub 2019 Dec 31. Review.


Environmental pollutants in blood donors: The multicentre Norwegian donor study.

Averina M, Hervig T, Huber S, Kjaer M, Kristoffersen EK, Bolann B.

Transfus Med. 2020 Jan 11. doi: 10.1111/tme.12662. [Epub ahead of print]


Early development of tendinopathy in humans: Sequence of pathological changes in structure and tissue turnover signaling.

Tran PHT, Malmgaard-Clausen NM, Puggaard RS, Svensson RB, Nybing JD, Hansen P, Schjerling P, Zinglersen AH, Couppé C, Boesen M, Magnusson SP, Kjaer M.

FASEB J. 2020 Jan;34(1):776-788. doi: 10.1096/fj.201901309R. Epub 2019 Nov 26.


Heterotopic Ossification After an Achilles Tendon Rupture Cannot Be Prevented by Early Functional Rehabilitation: A Cohort Study.

Magnusson SP, Agergaard AS, Couppé C, Svensson RB, Warming S, Krogsgaard MR, Kjaer M, Eliasson P.

Clin Orthop Relat Res. 2020 Jan 6. doi: 10.1097/CORR.0000000000001085. [Epub ahead of print]


[Christmas article: Coitus is not recommended - a systematic review].

Jespersen C, Celicanin MM, Wandall-Holm MF, Kirschner B, Kjær MM, Ingerslev MD, Schroll JB.

Ugeskr Laeger. 2019 Dec 9;181(50). pii: V70800. Danish.


Multinutrient Supplementation Increases Collagen Synthesis during Early Wound Repair in a Randomized Controlled Trial in Patients with Inguinal Hernia.

Kjaer M, Frederiksen AKS, Nissen NI, Willumsen N, van Hall G, Jorgensen LN, Andersen JR, Ågren MS.

J Nutr. 2020 Jan 3. pii: nxz324. doi: 10.1093/jn/nxz324. [Epub ahead of print]


Long-term patient-important outcomes after septic shock: A protocol for 1-year follow-up of the CLASSIC trial.

Kjaer MN, Meyhoff TS, Madsen MB, Hjortrup PB, Møller MH, Egerod I, Wetterslev J, Lange T, Cronhjort M, Laake JH, Jakob SM, Nalos M, Pettilä V, van der Horst ICC, Ostermann M, Mouncey P, Cecconi M, Ferrer R, Malbrain MLNG, Ahlstedt C, Hoffmann S, Bestle MH, Gyldensted L, Nebrich L, Russell L, Vang M, Sølling C, Brøchner AC, Rasmussen BS, Perner A.

Acta Anaesthesiol Scand. 2020 Mar;64(3):410-416. doi: 10.1111/aas.13519. Epub 2019 Dec 26.


Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability.

Ericsson H, Nelander K, Heijer M, Kjaer M, Lindstedt EL, Albayaty M, Forte P, Lagerström-Fermér M, Skrtic S.

Clin Pharmacol Drug Dev. 2019 Dec 2. doi: 10.1002/cpdd.756. [Epub ahead of print]


The influence of fibrillin-1 and physical activity upon tendon tissue morphology and mechanical properties in mice.

Tran PHT, Skrba T, Wondimu E, Galatioto G, Svensson RB, Olesen AT, Mackey AL, Magnusson SP, Ramirez F, Kjaer M.

Physiol Rep. 2019 Nov;7(21):e14267. doi: 10.14814/phy2.14267.


Early Growth Response Genes Increases Rapidly After Mechanical Overloading and Unloading in Tendon Constructs.

Herchenhan A, Dietrich-Zagonel F, Schjerling P, Kjaer M, Eliasson P.

J Orthop Res. 2020 Jan;38(1):173-181. doi: 10.1002/jor.24513. Epub 2019 Nov 19.


Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients.

Karlsen A, Cullum CK, Norheim KL, Scheel FU, Zinglersen AH, Vahlgren J, Schjerling P, Kjaer M, Mackey AL.

Med Sci Sports Exerc. 2020 Apr;52(4):773-784. doi: 10.1249/MSS.0000000000002191.


Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery.

EuroSurg Collaborative.

Br J Surg. 2020 Jan;107(2):e161-e169. doi: 10.1002/bjs.11326. Epub 2019 Oct 9.


Safety, Tolerability, and Pharmacokinetics of the Mineralocorticoid Receptor Modulator AZD9977 in Healthy Men: A Phase I Multiple Ascending Dose Study.

Whittaker A, Kragh ÅM, Hartleib-Geschwindner J, Albayaty M, Backlund A, Greasley PJ, Heijer M, Kjaer M, Forte P, Unwin R, Wernevik L, Ericsson H.

Clin Transl Sci. 2020 Mar;13(2):275-283. doi: 10.1111/cts.12705. Epub 2019 Oct 30.


An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise.

Ziegler AK, Damgaard A, Mackey AL, Schjerling P, Magnusson P, Olesen AT, Kjaer M, Scheele C.

Sci Rep. 2019 Aug 19;9(1):12069. doi: 10.1038/s41598-019-48587-2.


Molecular indicators of denervation in aging human skeletal muscle.

Soendenbroe C, Heisterberg MF, Schjerling P, Karlsen A, Kjaer M, Andersen JL, Mackey AL.

Muscle Nerve. 2019 Oct;60(4):453-463. doi: 10.1002/mus.26638. Epub 2019 Jul 29.


Influence of Oral Contraceptive Use on Adaptations to Resistance Training.

Dalgaard LB, Dalgas U, Andersen JL, Rossen NB, Møller AB, Stødkilde-Jørgensen H, Jørgensen JO, Kovanen V, Couppé C, Langberg H, Kjær M, Hansen M.

Front Physiol. 2019 Jul 2;10:824. doi: 10.3389/fphys.2019.00824. eCollection 2019.


Conservative vs liberal fluid therapy in septic shock (CLASSIC) trial-Protocol and statistical analysis plan.

Meyhoff TS, Hjortrup PB, Møller MH, Wetterslev J, Lange T, Kjaer MN, Jonsson AB, Hjortsø CJS, Cronhjort M, Laake JH, Jakob SM, Nalos M, Pettilä V, van der Horst I, Ostermann M, Mouncey P, Rowan K, Cecconi M, Ferrer R, Malbrain MLNG, Ahlstedt C, Hoffmann S, Bestle MH, Nebrich L, Russell L, Vang M, Rasmussen ML, Sølling C, Rasmussen BS, Brøchner AC, Perner A.

Acta Anaesthesiol Scand. 2019 Oct;63(9):1262-1271. doi: 10.1111/aas.13434. Epub 2019 Jul 24.


Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle.

Møller AB, Vendelbo MH, Schjerling P, Couppé C, Møller N, Kjær M, Hansen M, Jessen N.

Front Physiol. 2019 Jun 14;10:736. doi: 10.3389/fphys.2019.00736. eCollection 2019.


Effects of Long-Term Physical Activity and Diet on Skin Glycation and Achilles Tendon Structure.

Hjerrild JN, Wobbe A, Stausholm MB, Larsen AE, Josefsen CO, Malmgaard-Clausen NM, Dela F, Kjaer M, Magnusson SP, Hansen M, Svensson RB, Couppé C.

Nutrients. 2019 Jun 22;11(6). pii: E1409. doi: 10.3390/nu11061409.


Muscle-strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans.

Bayer ML, Bang L, Hoegberget-Kalisz M, Svensson RB, Olesen JL, Karlsson MM, Schjerling P, Hellsten Y, Hoier B, Magnusson SP, Kjaer M.

FASEB J. 2019 Sep;33(9):10369-10382. doi: 10.1096/fj.201900542R. Epub 2019 Jun 18.


Increasing Incidence of Pelvic Sepsis Following Ileal Pouch-Anal Anastomosis for Ulcerative Colitis in Denmark: A Nationwide Cohort Study.

Mark-Christensen A, Kjær MD, Ganesalingam S, Qvist N, Thorlacius-Ussing O, Rosenberg J, Hillingsø JG, Preisler L, Laurberg S.

Dis Colon Rectum. 2019 Aug;62(8):965-971. doi: 10.1097/DCR.0000000000001404.


Regional differences in turnover, composition, and mechanics of the porcine flexor tendon.

Zhang C, Svensson RB, Couppé C, Schjerling P, Skovgaard D, Kjaer M, Magnusson SP.

Connect Tissue Res. 2019 May 28:1-10. doi: 10.1080/03008207.2019.1620222. [Epub ahead of print]


The influence of direct and indirect fibroblast cell contact on human myogenic cell behavior and gene expression in vitro.

Bechshøft CJL, Schjerling P, Kjaer M, Mackey AL.

J Appl Physiol (1985). 2019 Aug 1;127(2):342-355. doi: 10.1152/japplphysiol.00215.2019. Epub 2019 May 23.


Postnatal intervention for the treatment of FNAIT: a systematic review.

Baker JM, Shehata N, Bussel J, Murphy MF, Greinacher A, Bakchoul T, Massey E, Lieberman L, Landry D, Tanael S, Arnold DM, Baidya S, Bertrand G, Kjaer M, Kaplan C, Kjeldsen-Kragh J, Oepkes D, Savoia H, Ryan G, Hume H; International Collaboration for Transfusion Medicine Guidelines (ICTMG).

J Perinatol. 2019 Oct;39(10):1329-1339. doi: 10.1038/s41372-019-0360-7. Epub 2019 Apr 10. Review.


Minimally invasive assessment of hepatic function in children with indocyanine green elimination: a validation study.

Nielsen J, Nerup N, Møller S, de Nijs R, Rasmussen A, Bo Svendsen L, Kjaer MS, Brix Christensen V, Borgwardt L.

Scand J Gastroenterol. 2019 Apr;54(4):485-491. doi: 10.1080/00365521.2019.1591497. Epub 2019 Mar 29.


Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies.

Yeung CC, Schjerling P, Heinemeier KM, Boesen AP, Dideriksen K, Kjær M.

Eur J Appl Physiol. 2019 Jun;119(6):1387-1394. doi: 10.1007/s00421-019-04129-2. Epub 2019 Mar 28.


HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a-immunized women.

Kjeldsen-Kragh J, Titze TL, Lie BA, Vaage JT, Kjær M.

Blood Adv. 2019 Apr 9;3(7):945-951. doi: 10.1182/bloodadvances.2019032227.


Age and prior exercise in vivo determine the subsequent in vitro molecular profile of myoblasts and nonmyogenic cells derived from human skeletal muscle.

Bechshøft CJL, Jensen SM, Schjerling P, Andersen JL, Svensson RB, Eriksen CS, Mkumbuzi NS, Kjaer M, Mackey AL.

Am J Physiol Cell Physiol. 2019 Jun 1;316(6):C898-C912. doi: 10.1152/ajpcell.00049.2019. Epub 2019 Mar 27.


PET/DW-MRI for evaluating treatment in chronic hepatitis C patients.

Petersen RJ, Nielsen NS, Johannesen HH, Hansen AE, Jespersen S, Arnbjerg CJ, Löfgren J, Kjær MS, Clausen MR, Kjær A, Nielsen SD, Fischer BM.

Am J Nucl Med Mol Imaging. 2019 Feb 15;9(1):84-92. eCollection 2019.


The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation.

Ziegler AK, Jensen SM, Schjerling P, Mackey AL, Andersen JL, Kjaer M.

Exp Gerontol. 2019 Jul 1;121:19-32. doi: 10.1016/j.exger.2019.03.007. Epub 2019 Mar 21.


Efficacy of Plug Treatment for Complex Anorectal Fistulae: Long-term Danish Results.

Hansen MS, Kjær ML, Andersen J.

Ann Coloproctol. 2019 Mar 20:123-128. doi: 10.3393/ac.2018.07.14. [Epub ahead of print]


Lack of muscle fibre hypertrophy, myonuclear addition, and satellite cell pool expansion with resistance training in 83-94-year-old men and women.

Karlsen A, Bechshøft RL, Malmgaard-Clausen NM, Andersen JL, Schjerling P, Kjaer M, Mackey AL.

Acta Physiol (Oxf). 2019 Sep;227(1):e13271. doi: 10.1111/apha.13271. Epub 2019 Mar 20.


Fetal and neonatal alloimmune thrombocytopenia: recommendations for evidence-based practice, an international approach.

Lieberman L, Greinacher A, Murphy MF, Bussel J, Bakchoul T, Corke S, Kjaer M, Kjeldsen-Kragh J, Bertrand G, Oepkes D, Baker JM, Hume H, Massey E, Kaplan C, Arnold DM, Baidya S, Ryan G, Savoia H, Landry D, Shehata N; International Collaboration for Transfusion Medicine Guidelines (ICTMG).

Br J Haematol. 2019 May;185(3):549-562. doi: 10.1111/bjh.15813. Epub 2019 Mar 3.


[Treatment of acute muscle injuries].

Bayer ML, Mackey A, Magnusson SP, Krogsgaard MR, Kjær M.

Ugeskr Laeger. 2019 Feb 18;181(8). pii: V11180753. Review. Danish.


Copenhagen Consensus statement 2019: physical activity and ageing.

Bangsbo J, Blackwell J, Boraxbekk CJ, Caserotti P, Dela F, Evans AB, Jespersen AP, Gliemann L, Kramer AF, Lundbye-Jensen J, Mortensen EL, Lassen AJ, Gow AJ, Harridge SDR, Hellsten Y, Kjaer M, Kujala UM, Rhodes RE, Pike ECJ, Skinner T, Skovgaard T, Troelsen J, Tulle E, Tully MA, van Uffelen JGZ, Viña J.

Br J Sports Med. 2019 Jul;53(14):856-858. doi: 10.1136/bjsports-2018-100451. Epub 2019 Feb 21.


Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes.

Gan LM, Lagerström-Fermér M, Carlsson LG, Arfvidsson C, Egnell AC, Rudvik A, Kjaer M, Collén A, Thompson JD, Joyal J, Chialda L, Koernicke T, Fuhr R, Chien KR, Fritsche-Danielson R.

Nat Commun. 2019 Feb 20;10(1):871. doi: 10.1038/s41467-019-08852-4.


Surgical Technique Influences Rehabilitation Regimen: Response.

Magnusson SP, Eliasson P, Agergaard AS, Couppe C, Svensson R, Krogsgaard M, Kjaer M.

Am J Sports Med. 2019 Jan;47(1):NP7. doi: 10.1177/0363546518810704. No abstract available.


Adalimumab in the treatment of chronic pouchitis. A randomized double-blind, placebo-controlled trial.

Kjær MD, Qvist N, Nordgaard-Lassen I, Christensen LA, Kjeldsen J.

Scand J Gastroenterol. 2019 Feb;54(2):188-193. doi: 10.1080/00365521.2019.1569718. Epub 2019 Feb 10.


Caring for non-sedated mechanically ventilated patients in ICU: A qualitative study comparing perspectives of expert and competent nurses.

Mortensen CB, Kjær MN, Egerod I.

Intensive Crit Care Nurs. 2019 Jun;52:35-41. doi: 10.1016/j.iccn.2019.01.004. Epub 2019 Feb 5.


Load magnitude affects patellar tendon mechanical properties but not collagen or collagen cross-linking after long-term strength training in older adults.

Eriksen CS, Svensson RB, Gylling AT, Couppé C, Magnusson SP, Kjaer M.

BMC Geriatr. 2019 Jan 31;19(1):30. doi: 10.1186/s12877-019-1043-0.


Reporting and interpreting missing health-related quality of life data in intensive care trials: Protocol for a systematic review.

Kjaer MN, Madsen MB, Møller MH, Egerod I, Perner A.

Acta Anaesthesiol Scand. 2019 Jul;63(6):796-801. doi: 10.1111/aas.13326. Epub 2019 Jan 30. Review.


Safety, tolerability, pharmacokinetics and effect on serum uric acid of the myeloperoxidase inhibitor AZD4831 in a randomized, placebo-controlled, phase I study in healthy volunteers.

Gan LM, Lagerström-Fermér M, Ericsson H, Nelander K, Lindstedt EL, Michaëlsson E, Kjaer M, Heijer M, Whatling C, Fuhr R.

Br J Clin Pharmacol. 2019 Apr;85(4):762-770. doi: 10.1111/bcp.13855. Epub 2019 Feb 18.


Prognostic molecular markers in pediatric liver disease - Are there any?

Nielsen J, Christensen VB, Borgwardt L, Rasmussen A, Østrup O, Kjær MS.

Biochim Biophys Acta Mol Basis Dis. 2019 Mar 1;1865(3):577-586. doi: 10.1016/j.bbadis.2018.12.018. Epub 2018 Dec 22.


Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systematic review.

Kjaer M, Bertrand G, Bakchoul T, Massey E, Baker JM, Lieberman L, Tanael S, Greinacher A, Murphy MF, Arnold DM, Baidya S, Bussel J, Hume H, Kaplan C, Oepkes D, Ryan G, Savoia H, Shehata N, Kjeldsen-Kragh J; International Collaboration for Transfusion Medicine Guidelines.

Vox Sang. 2019 Jan;114(1):79-94. doi: 10.1111/vox.12725. Epub 2018 Nov 22.


Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients.

Skrtic S, Tyrberg B, Broberg M, Ericsson H, Schnecke V, Kjaer M, Hompesch M, Andersson EM, Ryberg E, Aivazidis A, Wennberg Huldt C, Löfgren L, Morrow L, Parkinson J, Rydén-Bergsten T, Watkins E, Sörhede Winzell M.

PLoS One. 2018 Dec 17;13(12):e0208998. doi: 10.1371/journal.pone.0208998. eCollection 2018.


Integrated method for quantitative morphometry and oxygen transport modeling in striated muscle.

Al-Shammari AA, Kissane RWP, Holbek S, Mackey AL, Andersen TR, Gaffney EA, Kjaer M, Egginton S.

J Appl Physiol (1985). 2019 Mar 1;126(3):544-557. doi: 10.1152/japplphysiol.00170.2018. Epub 2018 Dec 6.


Corticosteroid injection is the best treatment in plantar fasciitis if combined with controlled training.

Johannsen FE, Herzog RB, Malmgaard-Clausen NM, Hoegberget-Kalisz M, Magnusson SP, Kjaer M.

Knee Surg Sports Traumatol Arthrosc. 2019 Jan;27(1):5-12. doi: 10.1007/s00167-018-5234-6. Epub 2018 Nov 15.


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