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Items: 1 to 50 of 113

1.

Data-driven analysis of JAK2V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms.

Pedersen RK, Andersen M, Knudsen TA, Sajid Z, Gudmand-Hoeyer J, Dam MJB, Skov V, Kjaer L, Ellervik C, Larsen TS, Hansen D, Pallisgaard N, Hasselbalch HC, Ottesen JT.

Cancer Med. 2020 Mar;9(6):2039-2051. doi: 10.1002/cam4.2741. Epub 2020 Jan 28.

2.

Evidence of immune elimination, immuno-editing and immune escape in patients with hematological cancer.

Holmström MO, Cordua S, Skov V, Kjær L, Pallisgaard N, Ellervik C, Hasselbalch HC, Andersen MH.

Cancer Immunol Immunother. 2020 Feb;69(2):315-324. doi: 10.1007/s00262-019-02473-y. Epub 2020 Jan 8. Review.

PMID:
31915854
3.

Ruxolitinib and interferon-α2 combination therapy for patients with polycythemia vera or myelofibrosis: a phase II study.

Sørensen AL, Mikkelsen SU, Knudsen TA, Bjørn ME, Andersen CL, Bjerrum OW, Brochmann N, Patel DA, Gjerdrum LMR, El Fassi D, Kruse TA, Larsen TS, Mourits-Andersen HT, Nielsen CH, Ellervik C, Pallisgaard N, Thomassen M, Kjær L, Skov V, Hasselbalch HC.

Haematologica. 2019 Dec 26. pii: haematol.2019.235648. doi: 10.3324/haematol.2019.235648. [Epub ahead of print]

4.

Smoking, blood cells and myeloproliferative neoplasms: meta-analysis and Mendelian randomization of 2·3 million people.

Jayasuriya NA, Kjaergaard AD, Pedersen KM, Sørensen AL, Bak M, Larsen MK, Nordestgaard BG, Bojesen SE, Çolak Y, Skov V, Kjaer L, Tolstrup JS, Hasselbalch HC, Ellervik C.

Br J Haematol. 2019 Dec 25. doi: 10.1111/bjh.16321. [Epub ahead of print]

PMID:
31875952
5.

Oxidatively generated modifications to nucleic acids in vivo: Measurement in urine and plasma.

Poulsen HE, Weimann A, Henriksen T, Kjær LK, Larsen EL, Carlsson ER, Christensen CK, Brandslund I, Fenger M.

Free Radic Biol Med. 2019 Dec;145:336-341. doi: 10.1016/j.freeradbiomed.2019.10.001. Epub 2019 Oct 3. Review.

PMID:
31586654
6.

The red blood cell count and the erythrocyte sedimentation rate in the diagnosis of polycythaemia vera.

Nersesjan V, Zervides KA, Sørensen AL, Kjaer L, Skov V, Hasselbalch HC.

Eur J Haematol. 2020 Jan;104(1):46-54. doi: 10.1111/ejh.13334. Epub 2019 Nov 22.

PMID:
31584701
7.

Quantifying the potential for bluetongue virus transmission in Danish cattle farms.

Haider N, Kjær LJ, Skovgård H, Nielsen SA, Bødker R.

Sci Rep. 2019 Sep 17;9(1):13466. doi: 10.1038/s41598-019-49866-8.

8.

Correction to: Functional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment.

Engelsdorf T, Kjaer L, Gigli-Bisceglia N, Vaahtera L, Bauer S, Miedes E, Wormit A, James L, Chairam I, Molina A, Hamann T.

BMC Plant Biol. 2019 Sep 5;19(1):385. doi: 10.1186/s12870-019-1995-4.

9.

Functional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment.

Engelsdorf T, Kjaer L, Gigli-Bisceglia N, Vaahtera L, Bauer S, Miedes E, Wormit A, James L, Chairam I, Molina A, Hamann T.

BMC Plant Biol. 2019 Jul 18;19(1):320. doi: 10.1186/s12870-019-1934-4. Erratum in: BMC Plant Biol. 2019 Sep 5;19(1):385.

10.

B-cell frequencies and immunoregulatory phenotypes in myeloproliferative neoplasms: Influence of ruxolitinib, interferon-α2, or combination treatment.

Sørensen AL, Bjørn ME, Riley CH, Holmstrøm M, Andersen MH, Svane IM, Mikkelsen SU, Skov V, Kjaer L, Hasselbalch HC, Nielsen CH.

Eur J Haematol. 2019 Oct;103(4):351-361. doi: 10.1111/ejh.13292. Epub 2019 Aug 18.

PMID:
31297883
11.

A large-scale screening for the taiga tick, Ixodes persulcatus, and the meadow tick, Dermacentor reticulatus, in southern Scandinavia, 2016.

Kjær LJ, Soleng A, Edgar KS, Lindstedt HEH, Paulsen KM, Andreassen ÅK, Korslund L, Kjelland V, Slettan A, Stuen S, Kjellander P, Christensson M, Teräväinen M, Baum A, Isbrand A, Jensen LM, Klitgaard K, Bødker R.

Parasit Vectors. 2019 Jul 9;12(1):338. doi: 10.1186/s13071-019-3596-3.

12.

Prevalence and phenotypes of JAK2 V617F and calreticulin mutations in a Danish general population.

Cordua S, Kjaer L, Skov V, Pallisgaard N, Hasselbalch HC, Ellervik C.

Blood. 2019 Aug 1;134(5):469-479. doi: 10.1182/blood.2019001113. Epub 2019 Jun 19. Erratum in: Blood. 2019 Oct 3;134(14):1195.

PMID:
31217187
13.

Multiple infections in questing nymphs and adult female Ixodes ricinus ticks collected in a recreational forest in Denmark.

Klitgaard K, Kjær LJ, Isbrand A, Hansen MF, Bødker R.

Ticks Tick Borne Dis. 2019 Aug;10(5):1060-1065. doi: 10.1016/j.ttbdis.2019.05.016. Epub 2019 May 31.

14.

Simulation of transmission and persistence of African swine fever in wild boar in Denmark.

Halasa T, Boklund A, Bøtner A, Mortensen S, Kjær LJ.

Prev Vet Med. 2019 Jun 1;167:68-79. doi: 10.1016/j.prevetmed.2019.03.028. Epub 2019 Apr 1.

PMID:
31027724
15.

Variant-specific discrepancy when quantitating BCR-ABL1 e13a2 and e14a2 transcripts using the Europe Against Cancer qPCR assay.

Kjaer L, Skov V, Andersen MT, Aggerholm A, Clair P, Gniot M, Soeby K, Udby L, Dorff MH, Hasselbalch H, Pallisgaard N.

Eur J Haematol. 2019 Jul;103(1):26-34. doi: 10.1111/ejh.13238. Epub 2019 May 1.

PMID:
30985947
16.

Predicting and mapping human risk of exposure to Ixodes ricinus nymphs using climatic and environmental data, Denmark, Norway and Sweden, 2016.

Kjær LJ, Soleng A, Edgar KS, Lindstedt HEH, Paulsen KM, Andreassen ÅK, Korslund L, Kjelland V, Slettan A, Stuen S, Kjellander P, Christensson M, Teräväinen M, Baum A, Klitgaard K, Bødker R.

Euro Surveill. 2019 Feb;24(9). doi: 10.2807/1560-7917.ES.2019.24.9.1800101.

17.

A Possible Connection Between Plant Longevity and the Absence of Protein Fibrillation: Basis for Identifying Aggregation Inhibitors in Plants.

Mohammad-Beigi H, Kjaer L, Eskandari H, Aliakbari F, Christiansen G, Ruvo G, Ward JL, Otzen DE.

Front Plant Sci. 2019 Feb 13;10:148. doi: 10.3389/fpls.2019.00148. eCollection 2019.

18.

High frequencies of circulating memory T cells specific for calreticulin exon 9 mutations in healthy individuals.

Holmström MO, Ahmad SM, Klausen U, Bendtsen SK, Martinenaite E, Riley CH, Svane IM, Kjær L, Skov V, Ellervik C, Pallisgaard N, Hasselbalch HC, Andersen MH.

Blood Cancer J. 2019 Jan 17;9(2):8. doi: 10.1038/s41408-018-0166-4.

19.

The effect of structured personal care on RNA oxidation: A 19-year follow-up of the randomized trial Diabetes Care in General Practice (DCGP).

Kjaer LK, Grand MK, Siersma V, Broedbaek K, Jorgensen A, de Fine Olivarius N, Poulsen HE.

J Diabetes Complications. 2019 Mar;33(3):202-207. doi: 10.1016/j.jdiacomp.2018.12.004. Epub 2018 Dec 11.

PMID:
30638771
20.

Exposure of non-target small mammals to anticoagulant rodenticide during chemical rodent control operations.

Elmeros M, Bossi R, Christensen TK, Kjær LJ, Lassen P, Topping CJ.

Environ Sci Pollut Res Int. 2019 Feb;26(6):6133-6140. doi: 10.1007/s11356-018-04064-3. Epub 2019 Jan 7.

PMID:
30617892
21.

Bridging blood cancers and inflammation: The reduced Cancitis model.

Ottesen JT, Pedersen RK, Sajid Z, Gudmand-Hoeyer J, Bangsgaard KO, Skov V, Kjær L, Knudsen TA, Pallisgaard N, Hasselbalch HC, Andersen M.

J Theor Biol. 2019 Mar 21;465:90-108. doi: 10.1016/j.jtbi.2019.01.001. Epub 2019 Jan 4.

PMID:
30615883
22.

International external quality assurance of JAK2 V617F quantification.

Asp J, Skov V, Bellosillo B, Kristensen T, Lippert E, Dicker F, Schwarz J, Wojtaszewska M, Palmqvist L, Akiki S, Aggerholm A, Tolstrup Andersen M, Girodon F, Kjær L, Oppliger Leibundgut E, Pancrazzi A, Vorland M, Andrikovics H, Kralovics R, Cassinat B, Coucelo M, Eftimov A, Haslam K, Kusec R, Link-Lenczowska D, Lodé L, Matiakowska K, Naguib D, Navaglia F, Novotny GW, Percy MJ, Sudarikov A, Hermouet S, Pallisgaard N.

Ann Hematol. 2019 May;98(5):1111-1118. doi: 10.1007/s00277-018-3570-8. Epub 2018 Dec 8.

23.

JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation.

Czech J, Cordua S, Weinbergerova B, Baumeister J, Crepcia A, Han L, Maié T, Costa IG, Denecke B, Maurer A, Schubert C, Feldberg K, Gezer D, Brümmendorf TH, Müller-Newen G, Mayer J, Racil Z, Kubesova B, Knudsen T, Sørensen AL, Holmström M, Kjær L, Skov V, Larsen TS, Hasselbalch HC, Chatain N, Koschmieder S.

Leukemia. 2019 Apr;33(4):995-1010. doi: 10.1038/s41375-018-0295-6. Epub 2018 Nov 23.

PMID:
30470838
24.

The annual, temporal and spatial pattern of Setaria tundra outbreaks in Finnish reindeer: a mechanistic transmission model approach.

Haider N, Laaksonen S, Kjær LJ, Oksanen A, Bødker R.

Parasit Vectors. 2018 Nov 12;11(1):565. doi: 10.1186/s13071-018-3159-z.

25.

RNA oxidation and iron levels in patients with diabetes.

Cejvanovic V, Kjær LK, Mørup Bergholdt HK, Henriksen T, Weimann A, Ellervik C, Poulsen HE.

Free Radic Biol Med. 2018 Dec;129:532-536. doi: 10.1016/j.freeradbiomed.2018.10.420. Epub 2018 Oct 16.

PMID:
30339885
26.

Indicator of RNA oxidation in urine for the prediction of mortality in patients with type 2 diabetes and microalbuminuria: A post-hoc analysis of the Steno-2 trial.

Kjaer LK, Oellgaard J, Henriksen T, Gaede P, Pedersen O, Poulsen HE.

Free Radic Biol Med. 2018 Dec;129:247-255. doi: 10.1016/j.freeradbiomed.2018.09.030. Epub 2018 Sep 21.

27.

Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function.

Laustsen A, Bak RO, Krapp C, Kjær L, Egedahl JH, Petersen CC, Pillai S, Tang HQ, Uldbjerg N, Porteus M, Roan NR, Nyegaard M, Denton PW, Jakobsen MR.

Nat Commun. 2018 Aug 30;9(1):3525. doi: 10.1038/s41467-018-05816-y.

28.

α-Synucleins from Animal Species Show Low Fibrillation Propensities and Weak Oligomer Membrane Disruption.

Sahin C, Kjær L, Christensen MS, N Pedersen J, Christiansen G, Pérez AW, Møller IM, Enghild JJ, Pedersen JS, Larsen K, Otzen DE.

Biochemistry. 2018 Aug 28;57(34):5145-5158. doi: 10.1021/acs.biochem.8b00627. Epub 2018 Aug 15.

PMID:
30067901
29.

Whole Blood Gene Expression Profiling in patients undergoing colon cancer surgery identifies differential expression of genes involved in immune surveillance, inflammation and carcinogenesis.

Watt SK, Hasselbalch HC, Skov V, Kjær L, Thomassen M, Kruse TA, Burton M, Gögenur I.

Surg Oncol. 2018 Jun;27(2):208-215. doi: 10.1016/j.suronc.2018.03.002. Epub 2018 Mar 27.

PMID:
29937173
30.

Safety and efficacy of combination therapy of interferon-α2 and ruxolitinib in polycythemia vera and myelofibrosis.

Mikkelsen SU, Kjaer L, Bjørn ME, Knudsen TA, Sørensen AL, Andersen CBL, Bjerrum OW, Brochmann N, Fassi DE, Kruse TA, Larsen TS, Mourits-Andersen HT, Nielsen CH, Pallisgaard N, Thomassen M, Skov V, Hasselbalch HC.

Cancer Med. 2018 Aug;7(8):3571-3581. doi: 10.1002/cam4.1619. Epub 2018 Jun 22.

31.

Pseudomonas aeruginosa rhamnolipid induces fibrillation of human α-synuclein and modulates its effect on biofilm formation.

Andersen KK, Vad BS, Kjaer L, Tolker-Nielsen T, Christiansen G, Otzen DE.

FEBS Lett. 2018 May;592(9):1484-1496. doi: 10.1002/1873-3468.13038. Epub 2018 Apr 10.

32.

Microclimatic temperatures at Danish cattle farms, 2000-2016: quantifying the temporal and spatial variation in the transmission potential of Schmallenberg virus.

Haider N, Cuellar AC, Kjær LJ, Sørensen JH, Bødker R.

Parasit Vectors. 2018 Mar 5;11(1):128. doi: 10.1186/s13071-018-2709-8.

33.

Spatial and temporal variation in the abundance of Culicoides biting midges (Diptera: Ceratopogonidae) in nine European countries.

Cuéllar AC, Kjær LJ, Kirkeby C, Skovgard H, Nielsen SA, Stockmarr A, Andersson G, Lindstrom A, Chirico J, Lühken R, Steinke S, Kiel E, Gethmann J, Conraths FJ, Larska M, Hamnes I, Sviland S, Hopp P, Brugger K, Rubel F, Balenghien T, Garros C, Rakotoarivony I, Allène X, Lhoir J, Chavernac D, Delécolle JC, Mathieu B, Delécolle D, Setier-Rio ML, Venail R, Scheid B, Chueca MÁM, Barceló C, Lucientes J, Estrada R, Mathis A, Tack W, Bødker R.

Parasit Vectors. 2018 Feb 27;11(1):112. doi: 10.1186/s13071-018-2706-y.

34.

Iron induced RNA-oxidation in the general population and in mouse tissue.

Cejvanovic V, Kjær LK, Bergholdt HKM, Torp-Pedersen A, Henriksen T, Weimann A, Ellervik C, Poulsen HE.

Free Radic Biol Med. 2018 Feb 1;115:127-135. doi: 10.1016/j.freeradbiomed.2017.11.013. Epub 2017 Nov 20.

PMID:
29157668
35.

Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses.

Carstensen H, Kjær L, Haugaard MM, Flethøj M, Hesselkilde EZ, Kanters JK, Pehrson S, Buhl R, Jespersen T.

J Cardiovasc Pharmacol. 2018 Jan;71(1):26-35. doi: 10.1097/FJC.0000000000000541.

36.

Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study.

Kjær LK, Cejvanovic V, Henriksen T, Petersen KM, Hansen T, Pedersen O, Christensen CK, Torp-Pedersen C, Gerds TA, Brandslund I, Mandrup-Poulsen T, Poulsen HE.

Diabetes Care. 2017 Dec;40(12):1771-1778. doi: 10.2337/dc17-1150. Epub 2017 Oct 23.

PMID:
29061564
37.

Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development.

Andersen M, Sajid Z, Pedersen RK, Gudmand-Hoeyer J, Ellervik C, Skov V, Kjær L, Pallisgaard N, Kruse TA, Thomassen M, Troelsen J, Hasselbalch HC, Ottesen JT.

PLoS One. 2017 Aug 31;12(8):e0183620. doi: 10.1371/journal.pone.0183620. eCollection 2017.

38.

Microclimatic temperatures increase the potential for vector-borne disease transmission in the Scandinavian climate.

Haider N, Kirkeby C, Kristensen B, Kjær LJ, Sørensen JH, Bødker R.

Sci Rep. 2017 Aug 15;7(1):8175. doi: 10.1038/s41598-017-08514-9.

39.

Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes.

Kjaer L, Holmström MO, Cordua S, Andersen MH, Svane IM, Thomassen M, Kruse TA, Pallisgaard N, Skov V, Hasselbalch HC.

Leuk Lymphoma. 2018 Apr;59(4):973-977. doi: 10.1080/10428194.2017.1359743. Epub 2017 Aug 9. No abstract available.

PMID:
28792253
40.

The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy.

Holmström MO, Martinenaite E, Ahmad SM, Met Ö, Friese C, Kjær L, Riley CH, Thor Straten P, Svane IM, Hasselbalch HC, Andersen MH.

Leukemia. 2018 Feb;32(2):429-437. doi: 10.1038/leu.2017.214. Epub 2017 Jul 5.

PMID:
28676668
41.

The effect of empagliflozin on oxidative nucleic acid modifications in patients with type 2 diabetes: protocol for a randomised, double-blinded, placebo-controlled trial.

Larsen EL, Cejvanovic V, Kjær LK, Vilsbøll T, Knop FK, Rungby J, Poulsen HE.

BMJ Open. 2017 May 9;7(5):e014728. doi: 10.1136/bmjopen-2016-014728.

42.

The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes.

Sørensen AS, Kjær LK, Petersen KM, Henriksen T, Cejvanovic V, Pedersen O, Hansen T, Christensen CK, Brandslund I, Poulsen HE.

Scand J Clin Lab Invest. 2017 Jul;77(4):253-258. doi: 10.1080/00365513.2017.1299208. Epub 2017 Mar 13.

PMID:
28287274
43.

Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials.

Larsen EL, Cejvanovic V, Kjaer LK, Pedersen MT, Popik SD, Hansen LK, Andersen JT, Jimenez-Solem E, Broedbaek K, Petersen M, Weimann A, Henriksen T, Lykkesfeldt J, Torp-Pedersen C, Poulsen HE.

Br J Clin Pharmacol. 2017 Aug;83(8):1643-1653. doi: 10.1111/bcp.13261. Epub 2017 Mar 17.

44.

The impact of interferon-alpha2 on HLA genes in patients with polycythemia vera and related neoplasms.

Skov V, Riley CH, Thomassen M, Kjær L, Stauffer Larsen T, Bjerrum OW, Kruse TA, Hasselbalch HC.

Leuk Lymphoma. 2017 Aug;58(8):1914-1921. doi: 10.1080/10428194.2016.1262032. Epub 2016 Dec 2.

PMID:
27911124
45.

Differential Dynamics of CALR Mutant Allele Burden in Myeloproliferative Neoplasms during Interferon Alfa Treatment.

Kjær L, Cordua S, Holmström MO, Thomassen M, Kruse TA, Pallisgaard N, Larsen TS, de Stricker K, Skov V, Hasselbalch HC.

PLoS One. 2016 Oct 20;11(10):e0165336. doi: 10.1371/journal.pone.0165336. eCollection 2016.

46.

Markers of oxidative stress in obese men with and without hypertension.

Cejvanovic V, Asferg C, Kjær LK, Andersen UB, Linneberg A, Frystyk J, Henriksen T, Flyvbjerg A, Christiansen M, Weimann A, Jeppesen J, Poulsen HE.

Scand J Clin Lab Invest. 2016 Dec;76(8):620-625. Epub 2016 Sep 26.

PMID:
27666677
47.

A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis.

Skov V, Burton M, Thomassen M, Stauffer Larsen T, Riley CH, Brinch Madelung A, Kjær L, Bondo H, Stamp I, Ehinger M, Dahl-Sørensen R, Brochmann N, Nielsen K, Thiele J, Jensen MK, Weis Bjerrum O, Kruse TA, Hasselbalch HC.

PLoS One. 2016 Aug 31;11(8):e0161570. doi: 10.1371/journal.pone.0161570. eCollection 2016.

48.

Alpha-synuclein and familial variants affect the chain order and the thermotropic phase behavior of anionic lipid vesicles.

Pantusa M, Vad B, Lillelund O, Kjær L, Otzen D, Bartucci R.

Biochim Biophys Acta. 2016 Sep;1864(9):1206-1214. doi: 10.1016/j.bbapap.2016.05.003. Epub 2016 May 10.

PMID:
27177693
49.

[Communication skills training in Denmark has come a long way].

Kjær LB, Møller JE, O'Connor M, Christiansen M, Ørntoft MB, Mørcke AM.

Ugeskr Laeger. 2016 Feb 15;178(7):V09150740. Review. Danish.

PMID:
27063007
50.

Social affiliation and contact patterns among white-tailed deer in disparate landscapes: implications for disease transmission.

Schauber EM, Nielsen CK, Kjær LJ, Anderson CW, Storm DJ.

J Mammal. 2015 Feb 15;96(1):16-28. Epub 2015 Mar 27.

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