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Items: 1 to 50 of 231

1.

Establishment of immortalized primary cell from the critically endangered Bonin flying fox (Pteropus pselaphon).

Tani T, Eitsuka T, Katayama M, Nagamine T, Nakaya Y, Suzuki H, Kiyono T, Nakagawa K, Inoue-Murayama M, Onuma M, Fukuda T.

PLoS One. 2019 Aug 26;14(8):e0221364. doi: 10.1371/journal.pone.0221364. eCollection 2019.

2.

Human-Derived Corneal Epithelial Cells Expressing Cell Cycle Regulators as a New Resource for in vitro Ocular Toxicity Testing.

Fukuda T, Gouko R, Eitsuka T, Suzuki R, Takahashi K, Nakagawa K, Sugano E, Tomita H, Kiyono T.

Front Genet. 2019 Jul 16;10:587. doi: 10.3389/fgene.2019.00587. eCollection 2019.

3.

An Ex-Vivo Culture System of Ovarian Cancer Faithfully Recapitulating the Pathological Features of Primary Tumors.

Ghani FI, Dendo K, Watanabe R, Yamada K, Yoshimatsu Y, Yugawa T, Nakahara T, Tanaka K, Yoshida H, Yoshida M, Ishikawa M, Goshima N, Kato T, Kiyono T.

Cells. 2019 Jun 26;8(7). pii: E644. doi: 10.3390/cells8070644.

4.

Cancer extracellular vesicles contribute to stromal heterogeneity by inducing chemokines in cancer-associated fibroblasts.

Naito Y, Yamamoto Y, Sakamoto N, Shimomura I, Kogure A, Kumazaki M, Yokoi A, Yashiro M, Kiyono T, Yanagihara K, Takahashi RU, Hirakawa K, Yasui W, Ochiya T.

Oncogene. 2019 Jul;38(28):5566-5579. doi: 10.1038/s41388-019-0832-4. Epub 2019 May 30.

5.

Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma.

Sekine S, Kiyono T, Ryo E, Ogawa R, Wakai S, Ichikawa H, Suzuki K, Arai S, Tsuta K, Ishida M, Sasajima Y, Goshima N, Yamazaki N, Mori T.

J Clin Invest. 2019 May 30;130:3827-3832. doi: 10.1172/JCI126185.

6.

Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance.

Murakami I, Egawa N, Griffin H, Yin W, Kranjec C, Nakahara T, Kiyono T, Doorbar J.

PLoS Pathog. 2019 May 13;15(5):e1007755. doi: 10.1371/journal.ppat.1007755. eCollection 2019 May.

7.

C-X-C Motif Chemokine Ligand 14 is a Unique Multifunctional Regulator of Tumor Progression.

Yang XY, Ozawa S, Kato Y, Maehata Y, Izukuri K, Ikoma T, Kanamori K, Akasaka T, Suzuki K, Iwabuchi H, Kurata SI, Katoh I, Sakurai T, Kiyono T, Hata RI.

Int J Mol Sci. 2019 Apr 16;20(8). pii: E1872. doi: 10.3390/ijms20081872. Review.

8.

Whole-Genome Analysis of Human Papillomavirus Type 16 Prevalent in Japanese Women with or without Cervical Lesions.

Hirose Y, Onuki M, Tenjimbayashi Y, Yamaguchi-Naka M, Mori S, Tasaka N, Satoh T, Morisada T, Iwata T, Kiyono T, Mimura T, Sekizawa A, Matsumoto K, Kukimoto I.

Viruses. 2019 Apr 16;11(4). pii: E350. doi: 10.3390/v11040350.

9.

Rat-derived feeder cells immortalized by expression of mutant CDK4, cyclin D, and telomerase can support stem cell growth.

Katayama M, Kiyono T, Kuroda K, Ueda K, Onuma M, Shirakawa H, Fukuda T.

Biochim Biophys Acta Mol Cell Res. 2019 May;1866(5):945-956. doi: 10.1016/j.bbamcr.2019.02.013. Epub 2019 Mar 1.

PMID:
30826331
10.

Autonomous trisomic rescue of Down syndrome cells.

Inoue M, Kajiwara K, Yamaguchi A, Kiyono T, Samura O, Akutsu H, Sago H, Okamoto A, Umezawa A.

Lab Invest. 2019 Jun;99(6):885-897. doi: 10.1038/s41374-019-0230-0. Epub 2019 Feb 13.

11.

The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway.

Ogishima J, Taguchi A, Kawata A, Kawana K, Yoshida M, Yoshimatsu Y, Sato M, Nakamura H, Kawata Y, Nishijima A, Fujimoto A, Tomio K, Adachi K, Nagamatsu T, Oda K, Kiyono T, Osuga Y, Fujii T.

BMC Cancer. 2018 Dec 3;18(1):1201. doi: 10.1186/s12885-018-4922-4.

12.

Extended proliferation of chicken- and Okinawa rail-derived fibroblasts by expression of cell cycle regulators.

Katayama M, Kiyono T, Ohmaki H, Eitsuka T, Endoh D, Inoue-Murayama M, Nakajima N, Onuma M, Fukuda T.

J Cell Physiol. 2019 May;234(5):6709-6720. doi: 10.1002/jcp.27417. Epub 2018 Nov 11.

PMID:
30417340
13.

Albatross/FBF1 contributes to both centriole duplication and centrosome separation.

Inoko A, Yano T, Miyamoto T, Matsuura S, Kiyono T, Goshima N, Inagaki M, Hayashi Y.

Genes Cells. 2018 Dec;23(12):1023-1042. doi: 10.1111/gtc.12648. Epub 2018 Nov 13.

14.

Efficient immortalization of cells derived from critically endangered Tsushima leopard cat (Prionailurus bengalensis euptilurus) with expression of mutant CDK4, Cyclin D1, and telomerase reverse transcriptase.

Gouko R, Onuma M, Eitsuka T, Katayama M, Takahashi K, Nakagawa K, Inoue-Murayama M, Kiyono T, Fukuda T.

Cytotechnology. 2018 Dec;70(6):1619-1630. doi: 10.1007/s10616-018-0254-0. Epub 2018 Sep 17.

PMID:
30225752
15.

Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity.

Yoshida M, Taguchi A, Kawana K, Ogishima J, Adachi K, Kawata A, Nakamura H, Sato M, Fujimoto A, Inoue T, Tomio K, Mori M, Nagamatsu T, Arimoto T, Koga K, Hiraike OW, Oda K, Kiyono T, Osuga Y, Fujii T.

Int J Oncol. 2018 Oct;53(4):1580-1590. doi: 10.3892/ijo.2018.4504. Epub 2018 Jul 26.

16.

Keratinocyte differentiation induces APOBEC3A, 3B, and mitochondrial DNA hypermutation.

Wakae K, Nishiyama T, Kondo S, Izuka T, Que L, Chen C, Kase K, Kitamura K, Mohiuddin M, Wang Z, Ahasan MM, Nakamura M, Fujiwara H, Yoshizaki T, Hosomochi K, Tajima A, Nakahara T, Kiyono T, Muramatsu M.

Sci Rep. 2018 Jun 27;8(1):9745. doi: 10.1038/s41598-018-27930-z.

17.

Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta).

Fukuda T, Eitsuka T, Donai K, Kurita M, Saito T, Okamoto H, Kinoshita K, Katayama M, Nitto H, Uchida T, Onuma M, Sone H, Inoue-Murayama M, Kiyono T.

Sci Rep. 2018 Jun 20;8(1):9229. doi: 10.1038/s41598-018-27271-x.

18.

Reconstitution of high-grade serous ovarian carcinoma from primary fallopian tube secretory epithelial cells.

Nakamura K, Nakayama K, Ishikawa N, Ishikawa M, Sultana R, Kiyono T, Kyo S.

Oncotarget. 2017 Dec 8;9(16):12609-12619. doi: 10.18632/oncotarget.23035. eCollection 2018 Feb 27.

19.

EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.

Kasahara K, Aoki H, Kiyono T, Wang S, Kagiwada H, Yuge M, Tanaka T, Nishimura Y, Mizoguchi A, Goshima N, Inagaki M.

Nat Commun. 2018 Feb 22;9(1):758. doi: 10.1038/s41467-018-03117-y.

20.

Fibroblasts promote the collective invasion of ameloblastoma tumor cells in a 3D coculture model.

Fuchigami T, Koyama H, Kishida M, Nishizawa Y, Iijima M, Kibe T, Ueda M, Kiyono T, Maniwa Y, Nakamura N, Kishida S.

FEBS Open Bio. 2017 Nov 2;7(12):2000-2007. doi: 10.1002/2211-5463.12313. eCollection 2017 Dec.

21.

Interleukin-1beta (IL-1β)-induced Notch ligand Jagged1 suppresses mitogenic action of IL-1β on human dystrophic myogenic cells.

Nagata Y, Kiyono T, Okamura K, Goto YI, Matsuo M, Ikemoto-Uezumi M, Hashimoto N.

PLoS One. 2017 Dec 1;12(12):e0188821. doi: 10.1371/journal.pone.0188821. eCollection 2017.

22.

Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression.

Dendo K, Yugawa T, Nakahara T, Ohno SI, Goshima N, Arakawa H, Kiyono T.

Carcinogenesis. 2018 Feb 9;39(2):202-213. doi: 10.1093/carcin/bgx124.

23.

Reversible differentiation of immortalized human bladder smooth muscle cells accompanied by actin bundle reorganization.

Hashimoto N, Kiyono T, Saitow F, Asada M, Yoshida M.

PLoS One. 2017 Oct 19;12(10):e0186584. doi: 10.1371/journal.pone.0186584. eCollection 2017.

24.

Molecular analysis of keratocystic odontogenic tumor cell lines derived from sporadic and basal cell nevus syndrome patients.

Noguchi K, Wakai K, Kiyono T, Kawabe M, Yoshikawa K, Hashimoto-Tamaoki T, Kishimoto H, Nakano Y.

Int J Oncol. 2017 Dec;51(6):1731-1738. doi: 10.3892/ijo.2017.4146. Epub 2017 Oct 9.

PMID:
29039452
25.

Establishment and characterization of cell lines derived from complete hydatidiform mole.

Yamamoto E, Niimi K, Kiyono T, Yamamoto T, Nishino K, Nakamura K, Kotani T, Kajiyama H, Shibata K, Kikkawa F.

Int J Mol Med. 2017 Sep;40(3):614-622. doi: 10.3892/ijmm.2017.3067. Epub 2017 Jul 14.

26.

Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes.

Yoshimatsu Y, Nakahara T, Tanaka K, Inagawa Y, Narisawa-Saito M, Yugawa T, Ohno SI, Fujita M, Nakagama H, Kiyono T.

Cancer Sci. 2017 Jul;108(7):1303-1309. doi: 10.1111/cas.13264. Epub 2017 Jun 5.

27.

A novel method to generate single-cell-derived cancer-associated fibroblast clones.

Hashimoto H, Suda Y, Miyashita T, Ochiai A, Tsuboi M, Masutomi K, Kiyono T, Ishii G.

J Cancer Res Clin Oncol. 2017 Aug;143(8):1409-1419. doi: 10.1007/s00432-017-2409-3. Epub 2017 Mar 31.

PMID:
28364361
28.

Tumor necrosis factor-alpha inhibits differentiation of myogenic cells in human urethral rhabdosphincter.

Shinohara M, Sumino Y, Sato F, Kiyono T, Hashimoto N, Mimata H.

Int J Urol. 2017 Jun;24(6):461-467. doi: 10.1111/iju.13330. Epub 2017 Mar 22.

29.

Immortalized prairie vole-derived fibroblasts (VMF-K4DTs) can be transformed into pluripotent stem cells and provide a useful tool with which to determine optimal reprogramming conditions.

Katayama M, Hirayama T, Kiyono T, Onuma M, Tani T, Takeda S, Nishimori K, Fukuda T.

J Reprod Dev. 2017 Jun 21;63(3):311-318. doi: 10.1262/jrd.2016-164. Epub 2017 Mar 23.

30.

Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer.

Yokoi A, Yoshioka Y, Yamamoto Y, Ishikawa M, Ikeda SI, Kato T, Kiyono T, Takeshita F, Kajiyama H, Kikkawa F, Ochiya T.

Nat Commun. 2017 Mar 6;8:14470. doi: 10.1038/ncomms14470.

31.

Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor.

Mori S, Takeuchi T, Ishii Y, Yugawa T, Kiyono T, Nishina H, Kukimoto I.

J Virol. 2017 Feb 28;91(6). pii: e02413-16. doi: 10.1128/JVI.02413-16. Print 2017 Mar 15.

32.

GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.

Kayama K, Watanabe S, Takafuji T, Tsuji T, Hironaka K, Matsumoto M, Nakayama KI, Enari M, Kohno T, Shiraishi K, Kiyono T, Yoshida K, Sugimoto N, Fujita M.

EMBO Rep. 2017 Jan;18(1):123-137. doi: 10.15252/embr.201642444. Epub 2016 Nov 17.

33.

Embryoid Body-Explant Outgrowth Cultivation from Induced Pluripotent Stem Cells in an Automated Closed Platform.

Tone H, Yoshioka S, Akiyama H, Nishimura A, Ichimura M, Nakatani M, Kiyono T, Toyoda M, Watanabe M, Umezawa A.

Biomed Res Int. 2016;2016:7098987. doi: 10.1155/2016/7098987. Epub 2016 Aug 28.

34.

Diagnostic copper imaging of Menkes disease by synchrotron radiation-generated X-ray fluorescence analysis.

Kinebuchi M, Matsuura A, Kiyono T, Nomura Y, Kimura S.

Sci Rep. 2016 Sep 15;6:33247. doi: 10.1038/srep33247.

35.

Modeling mesothelioma utilizing human mesothelial cells reveals involvement of phospholipase-C beta 4 in YAP-active mesothelioma cell proliferation.

Kakiuchi T, Takahara T, Kasugai Y, Arita K, Yoshida N, Karube K, Suguro M, Matsuo K, Nakanishi H, Kiyono T, Nakamura S, Osada H, Sekido Y, Seto M, Tsuzuki S.

Carcinogenesis. 2016 Aug 24. pii: bgw084. [Epub ahead of print]

PMID:
27559111
36.

Modification of the Tumor Microenvironment in KRAS or c-MYC-Induced Ovarian Cancer-Associated Peritonitis.

Yoshida M, Taguchi A, Kawana K, Adachi K, Kawata A, Ogishima J, Nakamura H, Fujimoto A, Sato M, Inoue T, Nishida H, Furuya H, Tomio K, Arimoto T, Koga K, Wada-Hiraike O, Oda K, Nagamatsu T, Kiyono T, Osuga Y, Fujii T.

PLoS One. 2016 Aug 2;11(8):e0160330. doi: 10.1371/journal.pone.0160330. eCollection 2016.

37.

Cellular conservation of endangered midget buffalo (Lowland Anoa, Bubalus quarlesi) by establishment of primary cultured cell, and its immortalization with expression of cell cycle regulators.

Fukuda T, Iino Y, Eitsuka T, Onuma M, Katayama M, Murata K, Inoue-Murayama M, Hara K, Isogai E, Kiyono T.

Cytotechnology. 2016 Oct;68(5):1937-47. doi: 10.1007/s10616-016-0004-0. Epub 2016 Jul 23.

38.

Expression of the chemokine CXCL14 and cetuximab-dependent tumour suppression in head and neck squamous cell carcinoma.

Kondo T, Ozawa S, Ikoma T, Yang XY, Kanamori K, Suzuki K, Iwabuchi H, Maehata Y, Miyamoto C, Taguchi T, Kiyono T, Kubota E, Hata RI.

Oncogenesis. 2016 Jul 11;5(7):e240. doi: 10.1038/oncsis.2016.43.

39.

E6D25E, HPV16 Asian variant shows specific proteomic pattern correlating in cells transformation and suppressive innate immune response.

Chopjitt P, Pientong C, Sunthamala N, Kongyingyoes B, Haonon O, Boonmars T, Kikawa S, Nakahara T, Kiyono T, Ekalaksananan T.

Biochem Biophys Res Commun. 2016 Sep 9;478(1):417-423. doi: 10.1016/j.bbrc.2016.07.025. Epub 2016 Jul 5.

PMID:
27392712
40.

Cancer cachexia causes skeletal muscle damage via transient receptor potential vanilloid 2-independent mechanisms, unlike muscular dystrophy.

Iwata Y, Suzuki N, Ohtake H, Kamauchi S, Hashimoto N, Kiyono T, Wakabayashi S.

J Cachexia Sarcopenia Muscle. 2016 Jun;7(3):366-76. doi: 10.1002/jcsm.12067. Epub 2015 Nov 19.

41.

Reliable and versatile immortal muscle cell models from healthy and myotonic dystrophy type 1 primary human myoblasts.

Pantic B, Borgia D, Giunco S, Malena A, Kiyono T, Salvatori S, De Rossi A, Giardina E, Sangiuolo F, Pegoraro E, Vergani L, Botta A.

Exp Cell Res. 2016 Mar 1;342(1):39-51. doi: 10.1016/j.yexcr.2016.02.013. Epub 2016 Feb 19.

PMID:
26905645
42.

Highly Efficient CRISPR/Cas9-Mediated Cloning and Functional Characterization of Gastric Cancer-Derived Epstein-Barr Virus Strains.

Kanda T, Furuse Y, Oshitani H, Kiyono T.

J Virol. 2016 Apr 14;90(9):4383-93. doi: 10.1128/JVI.00060-16. Print 2016 May.

43.

Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway.

Inaba H, Goto H, Kasahara K, Kumamoto K, Yonemura S, Inoko A, Yamano S, Wanibuchi H, He D, Goshima N, Kiyono T, Hirotsune S, Inagaki M.

J Cell Biol. 2016 Feb 15;212(4):409-23. doi: 10.1083/jcb.201507046.

44.

[Life-Threatening Hyponatremia by Chemotherapy in a Patient with Non-Hodgkin's Lymphoma].

Morikawa G, Kinjo T, Hanaoka Y, Kiyono T, Okazawa K, Dan K.

Gan To Kagaku Ryoho. 2015 Dec;42(13):2493-6. Japanese.

PMID:
26809312
45.

Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma.

Yachida S, Wood LD, Suzuki M, Takai E, Totoki Y, Kato M, Luchini C, Arai Y, Nakamura H, Hama N, Elzawahry A, Hosoda F, Shirota T, Morimoto N, Hori K, Funazaki J, Tanaka H, Morizane C, Okusaka T, Nara S, Shimada K, Hiraoka N, Taniguchi H, Higuchi R, Oshima M, Okano K, Hirono S, Mizuma M, Arihiro K, Yamamoto M, Unno M, Yamaue H, Weiss MJ, Wolfgang CL, Furukawa T, Nakagama H, Vogelstein B, Kiyono T, Hruban RH, Shibata T.

Cancer Cell. 2016 Feb 8;29(2):229-40. doi: 10.1016/j.ccell.2015.12.012. Epub 2016 Jan 21.

46.

Induced Pluripotent Stem Cells With Six Reprogramming Factors From Prairie Vole, Which Is an Animal Model for Social Behaviors.

Katayama M, Hirayama T, Horie K, Kiyono T, Donai K, Takeda S, Nishimori K, Fukuda T.

Cell Transplant. 2016;25(5):783-96. doi: 10.3727/096368916X690502. Epub 2016 Jan 15.

PMID:
26777120
47.

Fatty acid analysis of triacylglycerols: Preparation of fatty acid methyl esters for gas chromatography.

Ichihara K, Kohsaka C, Tomari N, Kiyono T, Wada J, Hirooka K, Yamamoto Y.

Anal Biochem. 2016 Feb 15;495:6-8. doi: 10.1016/j.ab.2015.11.009. Epub 2015 Nov 30.

PMID:
26656926
48.

Immortalization of Fetal Bovine Colon Epithelial Cells by Expression of Human Cyclin D1, Mutant Cyclin Dependent Kinase 4, and Telomerase Reverse Transcriptase: An In Vitro Model for Bacterial Infection.

Kuroda K, Kiyono T, Isogai E, Masuda M, Narita M, Okuno K, Koyanagi Y, Fukuda T.

PLoS One. 2015 Dec 1;10(12):e0143473. doi: 10.1371/journal.pone.0143473. eCollection 2015.

49.

Aberrant Expression of the Cell Polarity Regulator aPKCλ/ι is Associated With Disease Progression in Cervical Intraepithelial Neoplasia (CIN): A Possible Marker for Predicting CIN Prognosis.

Mizushima T, Asai-Sato M, Akimoto K, Nagashima Y, Taguri M, Sasaki K, Nakaya MA, Asano R, Tokinaga A, Kiyono T, Hirahara F, Ohno S, Miyagi E.

Int J Gynecol Pathol. 2016 Mar;35(2):106-17. doi: 10.1097/PGP.0000000000000228.

PMID:
26535980
50.

Establishment of an immortalized cell line derived from the prairie vole via lentivirus-mediated transduction of mutant cyclin-dependent kinase 4, cyclin D, and telomerase reverse transcriptase.

Katayama M, Kiyono T, Horie K, Hirayama T, Eitsuka T, Kuroda K, Donai K, Hidema S, Nishimori K, Fukuda T.

Exp Anim. 2016;65(1):87-96. doi: 10.1538/expanim.15-0061. Epub 2015 Oct 23.

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