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Items: 1 to 50 of 227

1.

Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain.

Nishino T, Tamada K, Maeda A, Abe T, Kiyonari H, Funahashi Y, Kaibuchi K, Takumi T, Konishi H.

Mol Brain. 2019 Nov 12;12(1):94. doi: 10.1186/s13041-019-0512-x.

2.

Animal transgenesis now and beyond in the era of genome editing: Snapshots from the 15th Transgenic Technology Meeting (TT2019) in Kobe, Japan.

Kiyonari H, Furuta Y.

Genes Cells. 2019 Dec;24(12):762-767. doi: 10.1111/gtc.12725. Epub 2019 Nov 8.

PMID:
31701596
3.

Identification of U11snRNA as an endogenous agonist of TLR7-mediated immune pathogenesis.

Negishi H, Endo N, Nakajima Y, Nishiyama T, Tabunoki Y, Nishio J, Koshiba R, Matsuda A, Matsuki K, Okamura T, Negishi-Koga T, Ichinohe T, Takemura S, Ishiwata H, Iemura SI, Natsume T, Abe T, Kiyonari H, Doi T, Hangai S, Yanai H, Fujio K, Yamamoto K, Taniguchi T.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23653-23661. doi: 10.1073/pnas.1915326116. Epub 2019 Nov 6.

4.

Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride Flux.

Hori A, Nishide K, Yasukuni Y, Haga K, Kakuta W, Ishikawa Y, Hayes MJ, Ohnuma SI, Kiyonari H, Kimura K, Kondo T, Sasai N.

Sci Rep. 2019 Nov 4;9(1):15911. doi: 10.1038/s41598-019-52040-9.

5.

A Novel Birthdate-Labeling Method Reveals Segregated Parallel Projections of Mitral and External Tufted Cells in the Main Olfactory System.

Hirata T, Shioi G, Abe T, Kiyonari H, Kato S, Kobayashi K, Mori K, Kawasaki T.

eNeuro. 2019 Nov 20;6(6). pii: ENEURO.0234-19.2019. doi: 10.1523/ENEURO.0234-19.2019. Print 2019 Nov/Dec.

6.

Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate.

Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A.

Cell Rep. 2019 Oct 15;29(3):603-616.e5. doi: 10.1016/j.celrep.2019.09.019.

7.

Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death.

Sasaki K, Himeno A, Nakagawa T, Sasaki Y, Kiyonari H, Iwai K.

Nat Commun. 2019 Aug 28;10(1):3878. doi: 10.1038/s41467-019-11858-7.

8.

Induced 2C Expression and Implantation-Competent Blastocyst-like Cysts from Primed Pluripotent Stem Cells.

Kime C, Kiyonari H, Ohtsuka S, Kohbayashi E, Asahi M, Yamanaka S, Takahashi M, Tomoda K.

Stem Cell Reports. 2019 Sep 10;13(3):485-498. doi: 10.1016/j.stemcr.2019.07.011. Epub 2019 Aug 8.

9.

Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes.

Konno D, Kishida C, Maehara K, Ohkawa Y, Kiyonari H, Okada S, Matsuzaki F.

Development. 2019 Aug 13;146(15). pii: dev174243. doi: 10.1242/dev.174243.

PMID:
31371378
10.

Translationally controlled tumor protein (TCTP) plays a pivotal role in cardiomyocyte survival through a Bnip3-dependent mechanism.

Cai W, Fujita T, Hidaka Y, Jin H, Suita K, Shigeta M, Kiyonari H, Umemura M, Yokoyama U, Sadoshima J, Ishikawa Y.

Cell Death Dis. 2019 Jul 18;10(8):549. doi: 10.1038/s41419-019-1787-7.

11.

Author Correction: Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation.

Inoue N, Nishizumi H, Naritsuka H, Kiyonari H, Sakano H.

Nat Commun. 2019 Jul 10;10(1):3036. doi: 10.1038/s41467-019-11055-6.

12.

TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing.

Katsuno T, Belyantseva IA, Cartagena-Rivera AX, Ohta K, Crump SM, Petralia RS, Ono K, Tona R, Imtiaz A, Rehman A, Kiyonari H, Kaneko M, Wang YX, Abe T, Ikeya M, Fenollar-Ferrer C, Riordan GP, Wilson EA, Fitzgerald TS, Segawa K, Omori K, Ito J, Frolenkov GI, Friedman TB, Kitajiri SI.

JCI Insight. 2019 Jun 20;4(12). pii: 128561. doi: 10.1172/jci.insight.128561. eCollection 2019 Jun 20.

13.

Deletion of Class II ADP-Ribosylation Factors in Mice Causes Tremor by the Nav1.6 Loss in Cerebellar Purkinje Cell Axon Initial Segments.

Hosoi N, Shibasaki K, Hosono M, Konno A, Shinoda Y, Kiyonari H, Inoue K, Muramatsu SI, Ishizaki Y, Hirai H, Furuichi T, Sadakata T.

J Neurosci. 2019 Aug 7;39(32):6339-6353. doi: 10.1523/JNEUROSCI.2002-18.2019. Epub 2019 Jun 14.

PMID:
31201232
14.

Behavioral and neurological analyses of adult mice carrying null and distinct loss-of-receptor function mutations in protein tyrosine phosphatase receptor type Z (PTPRZ).

Tanga N, Kuboyama K, Kishimoto A, Kihara M, Kiyonari H, Watanabe T, Fujikawa A, Noda M.

PLoS One. 2019 Jun 13;14(6):e0217880. doi: 10.1371/journal.pone.0217880. eCollection 2019.

15.

Non-coding cis-element of Period2 is essential for maintaining organismal circadian behaviour and body temperature rhythmicity.

Doi M, Shimatani H, Atobe Y, Murai I, Hayashi H, Takahashi Y, Fustin JM, Yamaguchi Y, Kiyonari H, Koike N, Yagita K, Lee C, Abe M, Sakimura K, Okamura H.

Nat Commun. 2019 Jun 12;10(1):2563. doi: 10.1038/s41467-019-10532-2.

16.

Structured spike series specify gene expression patterns for olfactory circuit formation.

Nakashima A, Ihara N, Shigeta M, Kiyonari H, Ikegaya Y, Takeuchi H.

Science. 2019 Jul 5;365(6448). pii: eaaw5030. doi: 10.1126/science.aaw5030. Epub 2019 Jun 6.

PMID:
31171707
17.

Gli signaling pathway modulates fibroblast activation and facilitates scar formation in pulmonary fibrosis.

Tsukui T, Ueha S, Shichino S, Hashimoto S, Nakajima T, Shiraishi K, Kihara M, Kiyonari H, Inagaki Y, Matsushima K.

Biochem Biophys Res Commun. 2019 Jun 30;514(3):684-690. doi: 10.1016/j.bbrc.2019.05.011. Epub 2019 May 8.

PMID:
31078262
18.

Asrij/OCIAD1 suppresses CSN5-mediated p53 degradation and maintains mouse hematopoietic stem cell quiescence.

Sinha S, Dwivedi TR, Yengkhom R, Bheemsetty VA, Abe T, Kiyonari H, VijayRaghavan K, Inamdar MS.

Blood. 2019 May 30;133(22):2385-2400. doi: 10.1182/blood.2019000530. Epub 2019 Apr 5.

PMID:
30952670
19.

Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.

Morita M, Siddiqui N, Katsumura S, Rouya C, Larsson O, Nagashima T, Hekmatnejad B, Takahashi A, Kiyonari H, Zang M, St-Arnaud R, Oike Y, Giguère V, Topisirovic I, Okada-Hatakeyama M, Yamamoto T, Sonenberg N.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7973-7981. doi: 10.1073/pnas.1816023116. Epub 2019 Mar 29.

20.

PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover.

Xie MJ, Ishikawa Y, Yagi H, Iguchi T, Oka Y, Kuroda K, Iwata K, Kiyonari H, Matsuda S, Matsuzaki H, Yuzaki M, Fukazawa Y, Sato M.

Sci Rep. 2019 Mar 13;9(1):4305. doi: 10.1038/s41598-019-40838-6.

21.

Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.

Sasako T, Ohsugi M, Kubota N, Itoh S, Okazaki Y, Terai A, Kubota T, Yamashita S, Nakatsukasa K, Kamura T, Iwayama K, Tokuyama K, Kiyonari H, Furuta Y, Shibahara J, Fukayama M, Enooku K, Okushin K, Tsutsumi T, Tateishi R, Tobe K, Asahara H, Koike K, Kadowaki T, Ueki K.

Nat Commun. 2019 Feb 27;10(1):947. doi: 10.1038/s41467-019-08591-6.

22.

Ecrg4 deficiency extends the replicative capacity of neural stem cells in a Foxg1-dependent manner.

Nakatani Y, Kiyonari H, Kondo T.

Development. 2019 Feb 18;146(4). pii: dev168120. doi: 10.1242/dev.168120.

23.

Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice.

Imaeda A, Tanaka S, Tonegawa K, Fuchigami S, Obana M, Maeda M, Kihara M, Kiyonari H, Conway SJ, Fujio Y, Nakayama H.

Biochem Biophys Res Commun. 2019 Feb 26;510(1):149-155. doi: 10.1016/j.bbrc.2019.01.070. Epub 2019 Jan 23.

24.

The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice.

Tanga N, Kuboyama K, Kishimoto A, Kiyonari H, Shiraishi A, Suzuki R, Watanabe T, Fujikawa A, Noda M.

Glia. 2019 May;67(5):967-984. doi: 10.1002/glia.23583. Epub 2019 Jan 22.

PMID:
30667096
25.

Sox13 is a novel early marker for hair follicle development.

Noto M, Noguchi N, Ishimura A, Kiyonari H, Abe T, Suzuki T, Hasunuma N, Taira M, Manabe M, Osada SI.

Biochem Biophys Res Commun. 2019 Feb 19;509(4):862-868. doi: 10.1016/j.bbrc.2018.12.163. Epub 2019 Jan 11.

PMID:
30638933
26.

Dynamic organelle localization and cytoskeletal reorganization during preimplantation mouse embryo development revealed by live imaging of genetically encoded fluorescent fusion proteins.

Kiyonari H, Kaneko M, Abe T, Shioi G, Aizawa S, Furuta Y, Fujimori T.

Genesis. 2019 Feb;57(2):e23277. doi: 10.1002/dvg.23277. Epub 2019 Jan 13.

27.

Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility.

Konishi Y, Terai K, Furuta Y, Kiyonari H, Abe T, Ueda Y, Kinashi T, Hamazaki Y, Takaori-Kondo A, Matsuda M.

iScience. 2018 Dec 21;10:98-113. doi: 10.1016/j.isci.2018.11.025. Epub 2018 Nov 20.

28.

Hair follicle epidermal stem cells define a niche for tactile sensation.

Cheng CC, Tsutsui K, Taguchi T, Sanzen N, Nakagawa A, Kakiguchi K, Yonemura S, Tanegashima C, Keeley SD, Kiyonari H, Furuta Y, Tomono Y, Watt FM, Fujiwara H.

Elife. 2018 Oct 25;7. pii: e38883. doi: 10.7554/eLife.38883.

29.

Deletion of Long Isoform of Eukaryotic Elongation Factor 1Bδ Leads to Audiogenic Seizures and Aversive Stimulus-Induced Long-Lasting Activity Suppression in Mice.

Kaitsuka T, Kiyonari H, Shiraishi A, Tomizawa K, Matsushita M.

Front Mol Neurosci. 2018 Oct 2;11:358. doi: 10.3389/fnmol.2018.00358. eCollection 2018.

30.

ROSA26 reporter mouse lines and image analyses reveal distinct region-specific cell behaviors in the visceral endoderm.

Abe T, Kutsuna N, Kiyonari H, Furuta Y, Fujimori T.

Development. 2018 Nov 21;145(22). pii: dev165852. doi: 10.1242/dev.165852.

31.

Obesity in Yap transgenic mice is associated with TAZ downregulation.

Kamura K, Shin J, Kiyonari H, Abe T, Shioi G, Fukuhara A, Sasaki H.

Biochem Biophys Res Commun. 2018 Nov 2;505(3):951-957. doi: 10.1016/j.bbrc.2018.10.037. Epub 2018 Oct 9.

PMID:
30309656
32.

Muscarinic Acetylcholine Receptors Chrm1 and Chrm3 Are Essential for REM Sleep.

Niwa Y, Kanda GN, Yamada RG, Shi S, Sunagawa GA, Ukai-Tadenuma M, Fujishima H, Matsumoto N, Masumoto KH, Nagano M, Kasukawa T, Galloway J, Perrin D, Shigeyoshi Y, Ukai H, Kiyonari H, Sumiyama K, Ueda HR.

Cell Rep. 2018 Aug 28;24(9):2231-2247.e7. doi: 10.1016/j.celrep.2018.07.082.

33.

Human cystatin SN is an endogenous protease inhibitor that prevents allergic rhinitis.

Fukuoka A, Matsushita K, Morikawa T, Adachi T, Yasuda K, Kiyonari H, Fujieda S, Yoshimoto T.

J Allergy Clin Immunol. 2019 Mar;143(3):1153-1162.e12. doi: 10.1016/j.jaci.2018.06.035. Epub 2018 Aug 23.

PMID:
30012514
34.

Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation.

Inoue N, Nishizumi H, Naritsuka H, Kiyonari H, Sakano H.

Nat Commun. 2018 May 9;9(1):1842. doi: 10.1038/s41467-018-04239-z. Erratum in: Nat Commun. 2019 Jul 10;10(1):3036.

35.

Renal papillary tip extract stimulates BNP production and excretion from cardiomyocytes.

Goto I, Okamoto R, Hashizume R, Suzuki N, Ito R, Yamanaka K, Saito H, Kiyonari H, Tawara I, Kageyama Y, Ogihara Y, Ali Y, Yamada N, Katayama N, Ito M.

PLoS One. 2018 May 7;13(5):e0197078. doi: 10.1371/journal.pone.0197078. eCollection 2018.

36.

Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain.

Takeuchi A, Iida K, Tsubota T, Hosokawa M, Denawa M, Brown JB, Ninomiya K, Ito M, Kimura H, Abe T, Kiyonari H, Ohno K, Hagiwara M.

Cell Rep. 2018 May 1;23(5):1326-1341. doi: 10.1016/j.celrep.2018.03.141.

37.

Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice.

Yanai H, Chiba S, Hangai S, Kometani K, Inoue A, Kimura Y, Abe T, Kiyonari H, Nishio J, Taguchi-Atarashi N, Mizushima Y, Negishi H, Grosschedl R, Taniguchi T.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5253-5258. doi: 10.1073/pnas.1803936115. Epub 2018 Apr 30.

38.

Madagascar ground gecko genome analysis characterizes asymmetric fates of duplicated genes.

Hara Y, Takeuchi M, Kageyama Y, Tatsumi K, Hibi M, Kiyonari H, Kuraku S.

BMC Biol. 2018 Apr 16;16(1):40. doi: 10.1186/s12915-018-0509-4.

39.

Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning.

Shetty R, Joshi D, Jain M, Vasudevan M, Paul JC, Bhat G, Banerjee P, Abe T, Kiyonari H, VijayRaghavan K, Inamdar MS.

Sci Rep. 2018 Apr 4;8(1):5632. doi: 10.1038/s41598-018-24014-w.

40.

A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing.

Murakami TC, Mano T, Saikawa S, Horiguchi SA, Shigeta D, Baba K, Sekiya H, Shimizu Y, Tanaka KF, Kiyonari H, Iino M, Mochizuki H, Tainaka K, Ueda HR.

Nat Neurosci. 2018 Apr;21(4):625-637. doi: 10.1038/s41593-018-0109-1. Epub 2018 Mar 5.

PMID:
29507408
41.

Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice.

Sassa T, Tadaki M, Kiyonari H, Kihara A.

FASEB J. 2018 Jun;32(6):2966-2978. doi: 10.1096/fj.201700947R. Epub 2018 Jan 17.

PMID:
29401594
42.

Animal transgenesis on the fast track in the era of evolving genome editing technologies: report for TT2017 the 14th Transgenic Technology Meeting in Snowbird, Utah.

Furuta Y, Kiyonari H.

Transgenic Res. 2018 Feb;27(1):123-129. doi: 10.1007/s11248-018-0060-7. Epub 2018 Feb 3. No abstract available.

43.

The Inv compartment of renal cilia is an intraciliary signal-activating center to phosphorylate ANKS6.

Nakajima Y, Kiyonari H, Mukumoto Y, Yokoyama T.

Kidney Int. 2018 May;93(5):1108-1117. doi: 10.1016/j.kint.2017.11.016. Epub 2018 Feb 1.

PMID:
29395339
44.

Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency.

Ito N, Katoh K, Kushige H, Saito Y, Umemoto T, Matsuzaki Y, Kiyonari H, Kobayashi D, Soga M, Era T, Araki N, Furuta Y, Suda T, Kida Y, Ohta K.

Sci Rep. 2018 Jan 26;8(1):1634. doi: 10.1038/s41598-018-20057-1.

45.

Roles of Cdc42 and Rac in Bergmann glia during cerebellar corticogenesis.

Sakamoto I, Ueyama T, Hayashibe M, Nakamura T, Mohri H, Kiyonari H, Shigyo M, Tohda C, Saito N.

Exp Neurol. 2018 Apr;302:57-67. doi: 10.1016/j.expneurol.2017.12.003. Epub 2017 Dec 15.

PMID:
29253508
46.

Mechanosensory-Based Phase Coding of Odor Identity in the Olfactory Bulb.

Iwata R, Kiyonari H, Imai T.

Neuron. 2017 Dec 6;96(5):1139-1152.e7. doi: 10.1016/j.neuron.2017.11.008.

47.

Production of knock-in mice in a single generation from embryonic stem cells.

Ukai H, Kiyonari H, Ueda HR.

Nat Protoc. 2017 Dec;12(12):2513-2530. doi: 10.1038/nprot.2017.110. Epub 2017 Nov 16.

PMID:
29189772
48.

The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice.

Ushijima T, Fujimoto N, Matsuyama S, Kan-O M, Kiyonari H, Shioi G, Kage Y, Yamasaki S, Takeya R, Sumimoto H.

J Biol Chem. 2018 Jan 5;293(1):148-162. doi: 10.1074/jbc.M117.813931. Epub 2017 Nov 20.

49.

Enforced expression of MIR142, a target of chromosome translocation in human B-cell tumors, results in B-cell depletion.

Kuriyama K, Enomoto Y, Suzuki R, Watanuki J, Hosoi H, Yamashita Y, Murata S, Mushino T, Tamura S, Hanaoka N, Dyer M, Siebert R, Kiyonari H, Nakakuma H, Kitamura T, Sonoki T.

Int J Hematol. 2018 Mar;107(3):345-354. doi: 10.1007/s12185-017-2360-8. Epub 2017 Oct 25.

PMID:
29071477
50.

Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.

Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T.

Sci Rep. 2017 Oct 12;7(1):13026. doi: 10.1038/s41598-017-13432-x.

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