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Five-year Recurrence-free Survival After Surgery Followed by Oral Chemotherapy for Gastric Cancer With Portal Vein Tumor Thrombosis.

Yoshida Y, Beppu T, Kinoshita K, Sato N, Akahoshi S, Yuki H, Saito S, Kitaoka M, Nasu J.

Anticancer Res. 2019 Apr;39(4):2233-2238. doi: 10.21873/anticanres.13339.


A novel range-verification method using ionoacoustic wave generated from spherical gold markers for particle-beam therapy: a simulation study.

Takayanagi T, Uesaka T, Kitaoka M, Unlu MB, Umegaki K, Shirato H, Xing L, Matsuura T.

Sci Rep. 2019 Mar 8;9(1):4011. doi: 10.1038/s41598-019-38889-w.


Sharing of human milk oligosaccharides degradants within bifidobacterial communities in faecal cultures supplemented with Bifidobacterium bifidum.

Gotoh A, Katoh T, Sakanaka M, Ling Y, Yamada C, Asakuma S, Urashima T, Tomabechi Y, Katayama-Ikegami A, Kurihara S, Yamamoto K, Harata G, He F, Hirose J, Kitaoka M, Okuda S, Katayama T.

Sci Rep. 2018 Sep 18;8(1):13958. doi: 10.1038/s41598-018-32080-3.


Identification, functional characterization, and crystal structure determination of bacterial levoglucosan dehydrogenase.

Sugiura M, Nakahara M, Yamada C, Arakawa T, Kitaoka M, Fushinobu S.

J Biol Chem. 2018 Nov 9;293(45):17375-17386. doi: 10.1074/jbc.RA118.004963. Epub 2018 Sep 17.


Relationship between screen time and nutrient intake in Japanese children and adolescents: a cross-sectional observational study.

Tsujiguchi H, Hori D, Kambayashi Y, Hamagishi T, Asakura H, Mitoma J, Kitaoka M, Anyenda EO, Nguyen TTT, Yamada Y, Hayashi K, Konoshita T, Sagara T, Shibata A, Sasaki S, Nakamura H.

Environ Health Prev Med. 2018 Aug 7;23(1):34. doi: 10.1186/s12199-018-0725-0.


Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes.

Petrova B, Liu K, Tian C, Kitaoka M, Freinkman E, Yang J, Orr-Weaver TL.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E7978-E7986. doi: 10.1073/pnas.1807918115. Epub 2018 Aug 6.


A beginner's guide to rigor and reproducibility in fluorescence imaging experiments.

Lee JY, Kitaoka M.

Mol Biol Cell. 2018 Jul 1;29(13):1519-1525. doi: 10.1091/mbc.E17-05-0276.


Reduced iodinated contrast media for abdominal imaging by dual-layer spectral detector computed tomography for patients with kidney disease.

Saito H, Noda K, Ogasawara K, Atsuji S, Takaoka H, Kajihara H, Nasu J, Kitaoka M, Morishita S, Matsushita I, Katahira K.

Radiol Case Rep. 2018 Feb 23;13(2):437-443. doi: 10.1016/j.radcr.2018.01.028. eCollection 2018 Apr.


Spindle assembly in egg extracts of the Marsabit clawed frog, Xenopus borealis.

Kitaoka M, Heald R, Gibeaux R.

Cytoskeleton (Hoboken). 2018 Jun;75(6):244-257. doi: 10.1002/cm.21444. Epub 2018 Apr 17.


Mechanistic investigation of transcutaneous protein delivery using solid-in-oil nanodispersion: A case study with phycocyanin.

Hardiningtyas SD, Wakabayashi R, Kitaoka M, Tahara Y, Minamihata K, Goto M, Kamiya N.

Eur J Pharm Biopharm. 2018 Jun;127:44-50. doi: 10.1016/j.ejpb.2018.01.020. Epub 2018 Feb 3.


Expression and Characterization of Recombinant Sucrose Phosphorylase.

Zhang H, Sun X, Li W, Li T, Li S, Kitaoka M.

Protein J. 2018 Feb;37(1):93-100. doi: 10.1007/s10930-017-9754-6.


Paternal chromosome loss and metabolic crisis contribute to hybrid inviability in Xenopus.

Gibeaux R, Acker R, Kitaoka M, Georgiou G, van Kruijsbergen I, Ford B, Marcotte EM, Nomura DK, Kwon T, Veenstra GJC, Heald R.

Nature. 2018 Jan 18;553(7688):337-341. doi: 10.1038/nature25188. Epub 2018 Jan 10.


Transcutaneous pollinosis immunotherapy using a solid-in-oil nanodispersion system carrying T cell epitope peptide and R848.

Kitaoka M, Naritomi A, Kawabe Y, Kamihira M, Kamiya N, Goto M.

Bioeng Transl Med. 2017 Feb 3;2(1):102-108. doi: 10.1002/btm2.10048. eCollection 2017 Mar.


Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease.

Pagan JD, Kitaoka M, Anthony RM.

Cell. 2018 Jan 25;172(3):564-577.e13. doi: 10.1016/j.cell.2017.11.041. Epub 2017 Dec 21.


Discovery of α-l-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42.

Viborg AH, Katayama T, Arakawa T, Abou Hachem M, Lo Leggio L, Kitaoka M, Svensson B, Fushinobu S.

J Biol Chem. 2017 Dec 22;292(51):21092-21101. doi: 10.1074/jbc.M117.792598. Epub 2017 Oct 23.


Association between all-cause mortality and severity of depressive symptoms in patients with type 2 diabetes: Analysis from the Japan Diabetes Complications Study (JDCS).

Matsunaga S, Tanaka S, Fujihara K, Horikawa C, Iimuro S, Kitaoka M, Sato A, Nakamura J, Haneda M, Shimano H, Akanuma Y, Ohashi Y, Sone H.

J Psychosom Res. 2017 Aug;99:34-39. doi: 10.1016/j.jpsychores.2017.05.020. Epub 2017 May 31.


Transcutaneous immunotherapy of pollinosis using solid-in-oil nanodispersions loaded with T cell epitope peptides.

Kong Q, Kitaoka M, Wakabayashi R, Kamiya N, Goto M.

Int J Pharm. 2017 Aug 30;529(1-2):401-409. doi: 10.1016/j.ijpharm.2017.07.020. Epub 2017 Jul 10.


Influence of multi-leaf collimator leaf transmission on head and neck intensity-modulated radiation therapy and volumetric-modulated arc therapy planning.

Sasaki M, Tominaga M, Kamomae T, Ikushima H, Kitaoka M, Bando R, Sakuragawa K, Oita M.

Jpn J Radiol. 2017 Sep;35(9):511-525. doi: 10.1007/s11604-017-0661-8. Epub 2017 Jun 24.


A case of malignant peritoneal mesothelioma suggesting the utility of combining double-contrast radiography and endoscopy with computed tomography for diagnosis.

Saito H, Hasuda S, Nasu J, Kitaoka M, Matsushita I.

Clin J Gastroenterol. 2017 Aug;10(4):371-376. doi: 10.1007/s12328-017-0757-9. Epub 2017 Jun 23.


In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy.

Arlauckas SP, Garris CS, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ.

Sci Transl Med. 2017 May 10;9(389). pii: eaal3604. doi: 10.1126/scitranslmed.aal3604.


Molecular Insight into Evolution of Symbiosis between Breast-Fed Infants and a Member of the Human Gut Microbiome Bifidobacterium longum.

Yamada C, Gotoh A, Sakanaka M, Hattie M, Stubbs KA, Katayama-Ikegami A, Hirose J, Kurihara S, Arakawa T, Kitaoka M, Okuda S, Katayama T, Fushinobu S.

Cell Chem Biol. 2017 Apr 20;24(4):515-524.e5. doi: 10.1016/j.chembiol.2017.03.012. Epub 2017 Apr 6.


Efficacy and safety of sitagliptin as compared with glimepiride in Japanese patients with type 2 diabetes mellitus aged ≥ 60 years (START-J trial).

Terauchi Y, Yamada Y, Ishida H, Ohsugi M, Kitaoka M, Satoh J, Yabe D, Shihara N, Seino Y.

Diabetes Obes Metab. 2017 Aug;19(8):1188-1192. doi: 10.1111/dom.12933. Epub 2017 Apr 12.


Galacto-N-biose is neuroprotective against glutamate-induced excitotoxicity in vitro.

Shinoda Y, Nakajima Y, Iguchi H, Tatsumi S, Kitaoka M, Nakajima M, Takahashi T, Fujiwara Y, Furuichi T.

Eur J Pharmacol. 2016 Nov 15;791:711-717. doi: 10.1016/j.ejphar.2016.10.010. Epub 2016 Oct 8.


Introduction of H-antigens into oligosaccharides and sugar chains of glycoproteins using highly efficient 1,2-α-l-fucosynthase.

Sugiyama Y, Gotoh A, Katoh T, Honda Y, Yoshida E, Kurihara S, Ashida H, Kumagai H, Yamamoto K, Kitaoka M, Katayama T.

Glycobiology. 2016 Nov;26(11):1235-1247. doi: 10.1093/glycob/cww085. Epub 2016 Aug 22.


Solid-in-oil nanodispersions for transdermal drug delivery systems.

Kitaoka M, Wakabayashi R, Kamiya N, Goto M.

Biotechnol J. 2016 Nov;11(11):1375-1385. doi: 10.1002/biot.201600081. Epub 2016 Aug 16. Review.


Associations of Cough Prevalence with Ambient Polycyclic Aromatic Hydrocarbons, Nitrogen and Sulphur Dioxide: A Longitudinal Study.

Anyenda EO, Higashi T, Kambayashi Y, Nguyen TT, Michigami Y, Fujimura M, Hara J, Tsujiguchi H, Kitaoka M, Asakura H, Hori D, Yamada Y, Hayashi K, Hayakawa K, Nakamura H.

Int J Environ Res Public Health. 2016 Aug 9;13(8). pii: E800. doi: 10.3390/ijerph13080800.


The associations between lifestyles and mental health using the General Health Questionnaire 12-items are different dependently on age and sex: a population-based cross-sectional study in Kanazawa, Japan.

Hori D, Tsujiguchi H, Kambayashi Y, Hamagishi T, Kitaoka M, Mitoma J, Asakura H, Suzuki F, Anyenda EO, Nguyen TT, Hibino Y, Shibata A, Hayashi K, Sagara T, Sasahara S, Matsuzaki I, Hatta K, Konoshita T, Nakamura H.

Environ Health Prev Med. 2016 Nov;21(6):410-421. Epub 2016 Jun 6.


Erratum to: The relationship between hypertension and health-related quality of life: adjusted by chronic pain, chronic diseases, and life habits in the general middle-aged population in Japan.

Kitaoka M, Mitoma J, Asakura H, Anyenda OE, Nguyen TT, Hamagishi T, Hori D, Suzuki F, Shibata A, Horii M, Tsujiguchi H, Hibino Y, Kambayashi Y, Hitomi Y, Shikura N, Hiroyuki N.

Environ Health Prev Med. 2016 Jul;21(4):215-223. No abstract available.


Structural insights into the difference in substrate recognition of two mannoside phosphorylases from two GH130 subfamilies.

Ye Y, Saburi W, Odaka R, Kato K, Sakurai N, Komoda K, Nishimoto M, Kitaoka M, Mori H, Yao M.

FEBS Lett. 2016 Mar;590(6):828-37. doi: 10.1002/1873-3468.12105. Epub 2016 Mar 4.


A glycosynthase derived from an inverting chitinase with an extended binding cleft.

Ohnuma T, Dozen S, Honda Y, Kitaoka M, Fukamizo T.

J Biochem. 2016 Aug;160(2):93-100. doi: 10.1093/jb/mvw014. Epub 2016 Feb 22.


The relationship between hypertension and health-related quality of life: adjusted by chronic pain, chronic diseases, and life habits in the general middle-aged population in Japan.

Kitaoka M, Mitoma J, Asakura H, Anyenda OE, Nguyen TT, Hamagishi T, Hori D, Suzuki F, Shibata A, Horii M, Tsujiguchi H, Hibino Y, Kambayashi Y, Hitomi Y, Shikura N, Hiroyuki N.

Environ Health Prev Med. 2016 Jul;21(4):193-214. doi: 10.1007/s12199-016-0514-6. Epub 2016 Feb 18. Erratum in: Environ Health Prev Med. 2016 Jul;21(4):215-23.


Functional and Structural Analysis of a β-Glucosidase Involved in β-1,2-Glucan Metabolism in Listeria innocua.

Nakajima M, Yoshida R, Miyanaga A, Abe K, Takahashi Y, Sugimoto N, Toyoizumi H, Nakai H, Kitaoka M, Taguchi H.

PLoS One. 2016 Feb 17;11(2):e0148870. doi: 10.1371/journal.pone.0148870. eCollection 2016.


A Longitudinal Study of Association between Heavy Metals and Itchy Eyes, Coughing in Chronic Cough Patients: Related with Non-Immunoglobulin E Mediated Mechanism.

Nguyen TT, Higashi T, Kambayashi Y, Anyenda EO, Michigami Y, Hara J, Fujimura M, Tsujiguchi H, Kitaoka M, Asakura H, Hori D, Hibino Y, Konoshita T, Nakamura H.

Int J Environ Res Public Health. 2016 Jan 7;13(1). pii: E110. doi: 10.3390/ijerph13010110.


Characterization and crystal structure determination of β-1,2-mannobiose phosphorylase from Listeria innocua.

Tsuda T, Nihira T, Chiku K, Suzuki E, Arakawa T, Nishimoto M, Kitaoka M, Nakai H, Fushinobu S.

FEBS Lett. 2015 Dec 21;589(24 Pt B):3816-21. doi: 10.1016/j.febslet.2015.11.034. Epub 2015 Nov 26.


The crystal structure of an inverting glycoside hydrolase family 9 exo-β-D-glucosaminidase and the design of glycosynthase.

Honda Y, Arai S, Suzuki K, Kitaoka M, Fushinobu S.

Biochem J. 2016 Feb 15;473(4):463-72. doi: 10.1042/BJ20150966. Epub 2015 Nov 30.


An inverting β-1,2-mannosidase belonging to glycoside hydrolase family 130 from Dyadobacter fermentans.

Nihira T, Chiku K, Suzuki E, Nishimoto M, Fushinobu S, Kitaoka M, Ohtsubo K, Nakai H.

FEBS Lett. 2015 Nov 30;589(23):3604-10. doi: 10.1016/j.febslet.2015.10.008. Epub 2015 Oct 20.


Diversity of phosphorylases in glycoside hydrolase families.

Kitaoka M.

Appl Microbiol Biotechnol. 2015 Oct;99(20):8377-90. doi: 10.1007/s00253-015-6927-0. Epub 2015 Aug 21. Review.


Pharmacokinetics and skin-tissue penetration of daptomycin in rats.

Matsumoto K, Kitaoka M, Kuroda Y, Ikawa K, Morikawa N, Sasaki J, Iketani O, Iwata S, Horino T, Hori S, Kizu J.

Clin Pharmacol. 2015 May 21;7:79-82. doi: 10.2147/CPAA.S83447. eCollection 2015.


Crystal Structure and Substrate Recognition of Cellobionic Acid Phosphorylase, Which Plays a Key Role in Oxidative Cellulose Degradation by Microbes.

Nam YW, Nihira T, Arakawa T, Saito Y, Kitaoka M, Nakai H, Fushinobu S.

J Biol Chem. 2015 Jul 24;290(30):18281-92. doi: 10.1074/jbc.M115.664664. Epub 2015 Jun 3.


Transcutaneous Peptide Immunotherapy of Japanese Cedar Pollinosis Using Solid-in-Oil Nanodispersion Technology.

Kitaoka M, Shin Y, Kamiya N, Kawabe Y, Kamihira M, Goto M.

AAPS PharmSciTech. 2015 Dec;16(6):1418-24. doi: 10.1208/s12249-015-0333-x. Epub 2015 May 19.


Novel substrate specificities of two lacto-N-biosidases towards β-linked galacto-N-biose-containing oligosaccharides of globo H, Gb5, and GA1.

Gotoh A, Katoh T, Sugiyama Y, Kurihara S, Honda Y, Sakurama H, Kambe T, Ashida H, Kitaoka M, Yamamoto K, Katayama T.

Carbohydr Res. 2015 May 18;408:18-24. doi: 10.1016/j.carres.2015.03.005. Epub 2015 Mar 14.


Thyroid ultrasound findings in a follow-up survey of children from three Japanese prefectures: Aomori, Yamanashi, and Nagasaki.

Hayashida N, Imaizumi M, Shimura H, Furuya F, Okubo N, Asari Y, Nigawara T, Midorikawa S, Kotani K, Nakaji S, Ohtsuru A, Akamizu T, Kitaoka M, Suzuki S, Taniguchi N, Yamashita S, Takamura N.

Sci Rep. 2015 Mar 12;5:9046. doi: 10.1038/srep09046.


Prevalence of thyroid nodular lesions in children and adolescents.

Shimura H, Suzuki S, Fukushima T, Midorikawa S, Suzuki S, Hayashida N, Imaizumi M, Okubo N, Asari Y, Nigawara T, Furuya F, Kotani K, Nakaji S, Otsuru A, Akamizu T, Kitaoka M, Takamura N, Abe M, Ohto H, Taniguchi N, Yamashita S.

Fukushima J Med Sci. 2014;60(2):196-202. doi: 10.5387/fms.2014-28. Epub 2014 Dec 20. No abstract available.


Functional reassignment of Cellvibrio vulgaris EpiA to cellobiose 2-epimerase and an evaluation of the biochemical functions of the 4-O-β-D-mannosyl-D-glucose phosphorylase-like protein, UnkA.

Saburi W, Tanaka Y, Muto H, Inoue S, Odaka R, Nishimoto M, Kitaoka M, Mori H.

Biosci Biotechnol Biochem. 2015;79(6):969-77. doi: 10.1080/09168451.2015.1012146. Epub 2015 Feb 23.


Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase.

Sato M, Arakawa T, Nam YW, Nishimoto M, Kitaoka M, Fushinobu S.

Biochim Biophys Acta. 2015 May;1854(5):333-40. doi: 10.1016/j.bbapap.2015.01.011. Epub 2015 Jan 30.


Discovery of two β-1,2-mannoside phosphorylases showing different chain-length specificities from Thermoanaerobacter sp. X-514.

Chiku K, Nihira T, Suzuki E, Nishimoto M, Kitaoka M, Ohtsubo K, Nakai H.

PLoS One. 2014 Dec 12;9(12):e114882. doi: 10.1371/journal.pone.0114882. eCollection 2014.


Facile enzymatic synthesis of sugar 1-phosphates as substrates for phosphorylases using anomeric kinases.

Liu Y, Nishimoto M, Kitaoka M.

Carbohydr Res. 2015 Jan 12;401:1-4. doi: 10.1016/j.carres.2014.10.014. Epub 2014 Oct 25.


Transdermal immunization using solid-in-oil nanodispersion with CpG oligodeoxynucleotide adjuvants.

Kitaoka M, Naritomi A, Hirakawa Y, Kamiya N, Goto M.

Pharm Res. 2015 Apr;32(4):1486-92. doi: 10.1007/s11095-014-1554-5. Epub 2014 Nov 1.


Extracapsular extension of prostate cancer: diagnostic value of combined multiparametric magnetic resonance imaging and isovoxel 3-dimensional T2-weighted imaging at 1.5 T.

Itatani R, Namimoto T, Takaoka H, Katahira K, Morishita S, Kitani K, Hamada Y, Kitaoka M, Nakaura T, Yamashita Y.

J Comput Assist Tomogr. 2015 Jan-Feb;39(1):37-43. doi: 10.1097/RCT.0000000000000172.


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