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Items: 1 to 50 of 335

1.

Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Lam CK, Tian L, Belbachir N, Wnorowski A, Shrestha R, Ma N, Kitani T, Rhee JW, Wu JC.

Circ Res. 2019 Jul 5;125(2):212-222. doi: 10.1161/CIRCRESAHA.118.314202. Epub 2019 May 13.

PMID:
31079550
2.

A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles.

Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, Blau HM, Wu JC.

Cell Stem Cell. 2019 May 2;24(5):802-811.e5. doi: 10.1016/j.stem.2019.02.015. Epub 2019 Mar 14.

PMID:
30880024
3.

Human-Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Patients With Breast Cancer.

Kitani T, Ong SG, Lam CK, Rhee JW, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC.

Circulation. 2019 May 21;139(21):2451-2465. doi: 10.1161/CIRCULATIONAHA.118.037357.

PMID:
30866650
4.

Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development.

Guo H, Tian L, Zhang JZ, Kitani T, Paik DT, Lee WH, Wu JC.

Stem Cell Reports. 2019 Apr 9;12(4):772-786. doi: 10.1016/j.stemcr.2019.01.022. Epub 2019 Feb 28.

5.

Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity.

Sharma A, McKeithan WL, Serrano R, Kitani T, Burridge PW, Del Álamo JC, Mercola M, Wu JC.

Nat Protoc. 2018 Dec;13(12):3018-3041. doi: 10.1038/s41596-018-0076-8.

PMID:
30413796
6.

The DEAD-box RNA-binding protein DDX6 regulates parental RNA decay for cellular reprogramming to pluripotency.

Kami D, Kitani T, Nakamura A, Wakui N, Mizutani R, Ohue M, Kametani F, Akimitsu N, Gojo S.

PLoS One. 2018 Oct 1;13(10):e0203708. doi: 10.1371/journal.pone.0203708. eCollection 2018.

7.

Reply to: Preventive role of ramelteon and suvorexant for postoperative delirium after pharyngolaryngectomy with esophagectomy.

Booka E, Tsubosa Y, Matsumoto T, Takeuchi M, Kitani T, Nagaoka M, Imai A, Kamijo T, Iida Y, Shimada A, Takebayashi K, Niihara M, Mori K, Onitsuka T, Takeuchi H, Kitagawa Y.

Esophagus. 2018 Jul;15(3):207. doi: 10.1007/s10388-018-0610-3. Epub 2018 Apr 18. No abstract available.

PMID:
29951986
8.

Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells.

Ma N, Zhang JZ, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC.

Circulation. 2018 Dec 4;138(23):2666-2681. doi: 10.1161/CIRCULATIONAHA.117.032273.

PMID:
29914921
9.

Pluripotent Stem Cell-Derived Cardiomyocytes as a Platform for Cell Therapy Applications: Progress and Hurdles for Clinical Translation.

Oikonomopoulos A, Kitani T, Wu JC.

Mol Ther. 2018 Jul 5;26(7):1624-1634. doi: 10.1016/j.ymthe.2018.02.026. Epub 2018 Mar 6. Review.

10.

Comprehensive renoprotective effects of ipragliflozin on early diabetic nephropathy in mice.

Kamezaki M, Kusaba T, Komaki K, Fushimura Y, Watanabe N, Ikeda K, Kitani T, Yamashita N, Uehara M, Kirita Y, Shiotsu Y, Sakai R, Fukuda T, Yamazaki M, Fukui M, Matoba S, Tamagaki K.

Sci Rep. 2018 Mar 5;8(1):4029. doi: 10.1038/s41598-018-22229-5.

11.

SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation.

Lee J, Shao NY, Paik DT, Wu H, Guo H, Termglinchan V, Churko JM, Kim Y, Kitani T, Zhao MT, Zhang Y, Wilson KD, Karakikes I, Snyder MP, Wu JC.

Cell Stem Cell. 2018 Mar 1;22(3):428-444.e5. doi: 10.1016/j.stem.2018.02.005.

12.

A Case of the nephrotic syndrome in bone marrow transplantation recipient, histologically showing overlapped glomerular lesions of thrombotic microangiopathy and membranous nephropathy.

Masuzawa N, Nishimura A, Kitani T, Tamagaki K, Sugitani M, Nagoshi H, Kuroda J, Konishi E.

Pathol Int. 2017 Dec;67(12):620-625. doi: 10.1111/pin.12589. Epub 2017 Sep 20.

PMID:
28940837
13.

Postoperative delirium after pharyngolaryngectomy with esophagectomy: a role for ramelteon and suvorexant.

Booka E, Tsubosa Y, Matsumoto T, Takeuchi M, Kitani T, Nagaoka M, Imai A, Kamijo T, Iida Y, Shimada A, Takebayashi K, Niihara M, Mori K, Onitsuka T, Takeuchi H, Kitagawa Y.

Esophagus. 2017;14(3):229-234. doi: 10.1007/s10388-017-0570-z. Epub 2017 Jan 21.

14.

High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC.

Sci Transl Med. 2017 Feb 15;9(377). pii: eaaf2584. doi: 10.1126/scitranslmed.aaf2584.

15.

Renal artery stenosis following nilotinib administration in a patient with chronic myelogenous leukemia.

Hatsuse M, Daikoku Y, Tamoto Y, Uehara M, Kitani T, Tamagaki K, Fuchida SI, Okano A, Murakami S, Shimazaki C.

Rinsho Ketsueki. 2017;58(1):15-19. doi: 10.11406/rinketsu.58.15. Review. Japanese.

PMID:
28190859
16.

Hematopoietic Stem Cell Transplantation Nephropathy Associated with Chronic Graft-versus-Host Disease without Extrarenal Involvement.

Ishida R, Shimizu A, Kitani T, Nakata M, Ota N, Kado H, Shiotsu Y, Ishida M, Tamagaki K.

Intern Med. 2016;55(19):2837-2842. Epub 2016 Oct 1.

17.

Comparison of Salvage Total Pharyngolaryngectomy and Cervical Esophagectomy Between Hypopharyngeal Cancer and Cervical Esophageal Cancer.

Takebayashi K, Tsubosa Y, Kamijo T, Iida Y, Imai A, Nagaoka M, Kitani T, Niihara M, Booka E, Shimada A, Nakagawa M, Onitsuka T.

Ann Surg Oncol. 2017 Mar;24(3):778-784. doi: 10.1245/s10434-016-5474-y. Epub 2016 Oct 6.

PMID:
27714538
18.

Risk factors for complications after pharyngolaryngectomy with total esophagectomy.

Booka E, Tsubosa Y, Niihara M, Takagi W, Takebayashi K, Shimada A, Kitani T, Nagaoka M, Imai A, Kamijo T, Iida Y, Onitsuka T, Nakagawa M, Takeuchi H, Kitagawa Y.

Esophagus. 2016;13(4):317-322. Epub 2016 Mar 31.

19.

Efficacy of chlorophyll c2 for seasonal allergic rhinitis: single-center double-blind randomized control trial.

Fujiwara T, Nishida N, Nota J, Kitani T, Aoishi K, Takahashi H, Sugahara T, Hato N.

Eur Arch Otorhinolaryngol. 2016 Dec;273(12):4289-4294. doi: 10.1007/s00405-016-4133-z. Epub 2016 Jun 9.

PMID:
27277115
20.

Incidence and risk factors for postoperative delirium after major head and neck cancer surgery.

Booka E, Kamijo T, Matsumoto T, Takeuchi M, Kitani T, Nagaoka M, Imai A, Iida Y, Shimada A, Takebayashi K, Niihara M, Mori K, Onitsuka T, Tsubosa Y, Takeuchi H, Kitagawa Y.

J Craniomaxillofac Surg. 2016 Jul;44(7):890-4. doi: 10.1016/j.jcms.2016.04.032. Epub 2016 Apr 26.

PMID:
27235151
21.

Cardiac mesenchymal progenitors differentiate into adipocytes via Klf4 and c-Myc.

Kami D, Kitani T, Kawasaki T, Gojo S.

Cell Death Dis. 2016 Apr 14;7:e2190. doi: 10.1038/cddis.2016.31.

22.

Inorganic polyphosphates are important for cell survival and motility of human skin keratinocytes.

Simbulan-Rosenthal CM, Gaur A, Sanabria VA, Dussan LJ, Saxena R, Schmidt J, Kitani T, Chen YS, Rahim S, Uren A, Crooke E, Rosenthal DS.

Exp Dermatol. 2015 Aug;24(8):636-9. doi: 10.1111/exd.12729. Epub 2015 May 8. No abstract available.

PMID:
25869331
23.

Novel detergent for whole organ tissue engineering.

Kawasaki T, Kirita Y, Kami D, Kitani T, Ozaki C, Itakura Y, Toyoda M, Gojo S.

J Biomed Mater Res A. 2015 Oct;103(10):3364-73. doi: 10.1002/jbm.a.35474. Epub 2015 Jun 17.

PMID:
25850947
24.

Internalization of isolated functional mitochondria: involvement of macropinocytosis.

Kitani T, Kami D, Matoba S, Gojo S.

J Cell Mol Med. 2014 Aug;18(8):1694-703. doi: 10.1111/jcmm.12316. Epub 2014 Jun 9.

25.

Direct human mitochondrial transfer: a novel concept based on the endosymbiotic theory.

Kitani T, Kami D, Kawasaki T, Nakata M, Matoba S, Gojo S.

Transplant Proc. 2014 May;46(4):1233-6. doi: 10.1016/j.transproceed.2013.11.133.

PMID:
24815168
26.

Cardiac mesenchymal progenitors from postmortem cardiac tissues retained cellular characterization.

Kami D, Kitani T, Nakata M, Gojo S.

Transplant Proc. 2014 May;46(4):1194-7. doi: 10.1016/j.transproceed.2013.11.110.

PMID:
24815158
27.

Pleiotropic functions of magnetic nanoparticles for ex vivo gene transfer.

Kami D, Kitani T, Kishida T, Mazda O, Toyoda M, Tomitaka A, Ota S, Ishii R, Takemura Y, Watanabe M, Umezawa A, Gojo S.

Nanomedicine. 2014 Aug;10(6):1165-74. doi: 10.1016/j.nano.2014.03.018. Epub 2014 Apr 4.

PMID:
24709330
28.

Large-scale cell production of stem cells for clinical application using the automated cell processing machine.

Kami D, Watakabe K, Yamazaki-Inoue M, Minami K, Kitani T, Itakura Y, Toyoda M, Sakurai T, Umezawa A, Gojo S.

BMC Biotechnol. 2013 Nov 15;13:102. doi: 10.1186/1472-6750-13-102.

29.

A Japanese Family Suffering from Familial Juvenile Hyperuricemic Nephropathy due to a Rare Mutation of the Uromodulin Gene.

Nakayama M, Mori Y, Ota N, Ishida M, Shiotsu Y, Matsuoka E, Kado H, Ishida R, Nakata M, Kitani T, Tamagaki K, Sekita C, Taniguchi A.

Case Rep Nephrol Urol. 2012 Jan;2(1):15-9. doi: 10.1159/000337343. Epub 2012 Mar 14.

30.

Post-translational excision of the carboxyl-terminal segment of CaM kinase phosphatase N and its cytosolic occurrence in the brain.

Kitani T, Okuno S, Nakamura Y, Tokuno H, Takeuchi M, Fujisawa H.

J Neurochem. 2006 Jan;96(2):374-84. Epub 2005 Nov 3.

31.

Phase II clinical study of cladribine in the treatment of hairy cell leukemia.

Machii T, Chou T, Suzuki M, Ohe Y, Katagiri S, Kitano EK, Kitano K, Fujiyama Y, Izumi T, Shimazaki C, Nanba K, Ohashi Y, Kitani T; Cladribine Study Group.

Int J Hematol. 2005 Oct;82(3):230-5.

PMID:
16207596
32.
35.
36.

Diagnostic evaluation of 2', 5'-oligoadenylate synthetase activities and antibodies against Epstein-Barr virus and Coxiella burnetii in patients with chronic fatigue syndrome in Japan.

Ikuta K, Yamada T, Shimomura T, Kuratsune H, Kawahara R, Ikawa S, Ohnishi E, Sokawa Y, Fukushi H, Hirai K, Watanabe Y, Kurata T, Kitani T, Sairenji T.

Microbes Infect. 2003 Oct;5(12):1096-102.

PMID:
14554250
37.
38.
39.

The hematopoietic defect in PNH is not due to defective stroma, but is due to defective progenitor cells.

Nishimura J, Ware RE, Burnette A, Pendleton AL, Kitano K, Hirota T, Machii T, Kitani T, Smith CA, Rosse WF.

Blood Cells Mol Dis. 2002 Sep-Oct;29(2):159-67.

PMID:
12490282
40.

Stimulation of Ca(2+)/calmodulin-dependent protein kinase phosphatase by polycations.

Ishida A, Kameshita I, Kitani T, Okuno S, Takeuchi M, Fujisawa H.

Arch Biochem Biophys. 2002 Dec 15;408(2):229-38.

PMID:
12464276
41.

Acquired activated protein C resistance associated with anti-protein S antibody as a strong risk factor for DVT in non-SLE patients.

Nojima J, Kuratsune H, Suehisa E, Kawasaki T, Machii T, Kitani T, Iwatani Y, Kanakura Y.

Thromb Haemost. 2002 Nov;88(5):716-22.

PMID:
12428083
42.

Lack of effects of oxolinic acid on spermatogenesis in young adult and aged Wistar rats.

Yoshida M, Kitani T, Takenaka A, Kudoh K, Katsuda SI, Taya K, Kurokawa Y, Maekawa A.

Food Chem Toxicol. 2002 Dec;40(12):1815-25.

PMID:
12419696
43.

Brain regions involved in fatigue sensation: reduced acetylcarnitine uptake into the brain.

Kuratsune H, Yamaguti K, Lindh G, Evengård B, Hagberg G, Matsumura K, Iwase M, Onoe H, Takahashi M, Machii T, Kanakura Y, Kitani T, Långström B, Watanabe Y.

Neuroimage. 2002 Nov;17(3):1256-65.

PMID:
12414265
44.

Phosphorylation of calmodulin by Ca2+/calmodulin-dependent protein kinase IV.

Ishida A, Kameshita I, Okuno S, Kitani T, Fujisawa H.

Arch Biochem Biophys. 2002 Nov 1;407(1):72-82.

PMID:
12392717
45.

[Progress in the field of hematology in the last 100 years: Medical history of paroxysmal nocturnal hemoglobinuria].

Kitani T.

Nihon Naika Gakkai Zasshi. 2002 Jul 10;91(7):2078-83. Japanese. No abstract available.

PMID:
12187681
46.

Acquired activated protein C resistance is associated with the co-existence of anti-prothrombin antibodies and lupus anticoagulant activity in patients with systemic lupus erythematosus.

Nojima J, Kuratsune H, Suehisa E, Kawasaki T, Machii T, Kitani T, Iwatani Y, Kanakura Y.

Br J Haematol. 2002 Aug;118(2):577-83.

PMID:
12139749
47.

[Chronic fatigue syndrome (CFS)].

Kuratsune H, Kondo K, Ikuta K, Yamanishi K, Watanabe Y, Kitani T.

Nihon Naika Gakkai Zasshi. 2001 Dec 10;90(12):2431-7. Review. Japanese. No abstract available.

PMID:
11917868
48.

Identification and characterization of CaMKP-N, nuclear calmodulin-dependent protein kinase phosphatase.

Takeuchi M, Ishida A, Kameshita I, Kitani T, Okuno S, Fujisawa H.

J Biochem. 2001 Dec;130(6):833-40.

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