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Items: 1 to 50 of 534

1.

Suppression of STING associated with LKB1 loss in KRAS-driven lung cancer.

Kitajima S, Ivanova E, Guo S, Yoshida R, Campisi M, Sundararaman SK, Tange S, Mitsuishi Y, Thai TC, Masuda S, Piel BP, Sholl LM, Kirschmeier PT, Paweletz CP, Watanabe H, Yajima M, Barbie DA.

Cancer Discov. 2018 Oct 8. pii: CD-18-0689. doi: 10.1158/2159-8290.CD-18-0689. [Epub ahead of print]

PMID:
30297358
2.

Correction: Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein levels predict the presence of fibrotic nonalcoholic steatohepatitis (NASH) and NASH cirrhosis.

Alkhouri N, Johnson C, Adams L, Kitajima S, Tsuruno C, Colpitts TL, Hatcho K, Lawitz E, Lopez R, Feldstein AE.

PLoS One. 2018 Oct 4;13(10):e0205541. doi: 10.1371/journal.pone.0205541. eCollection 2018.

3.

Enzymatic hydrolysis of PET: functional roles of three Ca2+ ions bound to a cutinase-like enzyme, Cut190*, and its engineering for improved activity.

Oda M, Yamagami Y, Inaba S, Oida T, Yamamoto M, Kitajima S, Kawai F.

Appl Microbiol Biotechnol. 2018 Sep 24. doi: 10.1007/s00253-018-9374-x. [Epub ahead of print]

PMID:
30250976
4.

Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS.

Kitajima S, Asahina H, Chen T, Guo S, Quiceno LG, Cavanaugh JD, Merlino AA, Tange S, Terai H, Kim JW, Wang X, Zhou S, Xu M, Wang S, Zhu Z, Thai TC, Takahashi C, Wang Y, Neve R, Stinson S, Tamayo P, Watanabe H, Kirschmeier PT, Wong KK, Barbie DA.

Cancer Cell. 2018 Sep 10;34(3):439-452.e6. doi: 10.1016/j.ccell.2018.08.009.

PMID:
30205046
5.

3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade.

Aref AR, Campisi M, Ivanova E, Portell A, Larios D, Piel BP, Mathur N, Zhou C, Coakley RV, Bartels A, Bowden M, Herbert Z, Hill S, Gilhooley S, Carter J, Cañadas I, Thai TC, Kitajima S, Chiono V, Paweletz CP, Barbie DA, Kamm RD, Jenkins RW.

Lab Chip. 2018 Oct 9;18(20):3129-3143. doi: 10.1039/c8lc00322j.

PMID:
30183789
6.

Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein levels predict the presence of fibrotic nonalcoholic steatohepatitis (NASH) and NASH cirrhosis.

Alkhouri N, Johnson C, Adams L, Kitajima S, Tsuruno C, Colpitts TL, Hatcho K, Lawitz E, Lopez R, Feldstein A.

PLoS One. 2018 Aug 30;13(8):e0202226. doi: 10.1371/journal.pone.0202226. eCollection 2018. Erratum in: PLoS One. 2018 Oct 4;13(10):e0205541.

7.

Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses.

Cañadas I, Thummalapalli R, Kim JW, Kitajima S, Jenkins RW, Christensen CL, Campisi M, Kuang Y, Zhang Y, Gjini E, Zhang G, Tian T, Sen DR, Miao D, Imamura Y, Thai T, Piel B, Terai H, Aref AR, Hagan T, Koyama S, Watanabe M, Baba H, Adeni AE, Lydon CA, Tamayo P, Wei Z, Herlyn M, Barbie TU, Uppaluri R, Sholl LM, Sicinska E, Sands J, Rodig S, Wong KK, Paweletz CP, Watanabe H, Barbie DA.

Nat Med. 2018 Aug;24(8):1143-1150. doi: 10.1038/s41591-018-0116-5. Epub 2018 Jul 23.

PMID:
30038220
8.

Author Correction: Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression.

Sun W, Kato H, Kitajima S, Lee KL, Gradin K, Okamoto T, Poellinger L.

Sci Rep. 2018 Jul 20;8(1):11239. doi: 10.1038/s41598-018-29095-1.

9.

Severe Maxillary Medication-related Osteonecrosis of the Jaw.

Kitajima S, Mizuno S, Kogiso R, Tsuji C.

Intern Med. 2018 Jul 6. doi: 10.2169/internalmedicine.0643-17. [Epub ahead of print] No abstract available.

10.

The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells.

Inoue M, Uchida Y, Edagawa M, Hirata M, Mitamura J, Miyamoto D, Taketani K, Sekine S, Kawauchi J, Kitajima S.

PLoS One. 2018 Jul 2;13(7):e0194160. doi: 10.1371/journal.pone.0194160. eCollection 2018.

11.

DNA damage response induced by Etoposide promotes steroidogenesis via GADD45A in cultured adrenal cells.

Tamamori-Adachi M, Koga A, Susa T, Fujii H, Tsuchiya M, Okinaga H, Hisaki H, Iizuka M, Kitajima S, Okazaki T.

Sci Rep. 2018 Jun 25;8(1):9636. doi: 10.1038/s41598-018-27938-5.

12.

Transcriptome analysis of Petunia axillaris flowers reveals genes involved in morphological differentiation and metabolite transport.

Amano I, Kitajima S, Suzuki H, Koeduka T, Shitan N.

PLoS One. 2018 Jun 14;13(6):e0198936. doi: 10.1371/journal.pone.0198936. eCollection 2018.

13.

Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR.

Joh K, Matsuhisa F, Kitajima S, Nishioka K, Higashimoto K, Yatsuki H, Kono T, Koseki H, Soejima H.

Epigenetics Chromatin. 2018 Jun 6;11(1):28. doi: 10.1186/s13072-018-0200-6.

14.

Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells.

Kitajima S, Lee KL, Fujioka M, Sun W, You J, Chia GS, Wanibuchi H, Tomita S, Araki M, Kato H, Poellinger L.

Oncotarget. 2018 Apr 10;9(27):19123-19135. doi: 10.18632/oncotarget.24919. eCollection 2018 Apr 10.

15.

Comparative multi-omics analysis reveals diverse latex-based defense strategies against pests among latex-producing organs of the fig tree (Ficus carica).

Kitajima S, Aoki W, Shibata D, Nakajima D, Sakurai N, Yazaki K, Munakata R, Taira T, Kobayashi M, Aburaya S, Savadogo EH, Hibino S, Yano H.

Planta. 2018 Jun;247(6):1423-1438. doi: 10.1007/s00425-018-2880-3. Epub 2018 Mar 13.

PMID:
29536219
16.

Hypoxia-inducible factor-1α promotes cell survival during ammonia stress response in ovarian cancer stem-like cells.

Kitajima S, Lee KL, Hikasa H, Sun W, Huang RY, Yang H, Matsunaga S, Yamaguchi T, Araki M, Kato H, Poellinger L.

Oncotarget. 2017 Dec 7;8(70):114481-114494. doi: 10.18632/oncotarget.23010. eCollection 2017 Dec 29.

17.

RASA1/NF1-Mutant Lung Cancer: Racing to the Clinic?

Kitajima S, Barbie DA.

Clin Cancer Res. 2018 Mar 15;24(6):1243-1245. doi: 10.1158/1078-0432.CCR-17-3597. Epub 2018 Jan 17.

PMID:
29343556
18.

Involvement of p38MAPK in Impaired Neutrophil Bactericidal Activity of Hemodialysis Patients.

Kamikawa Y, Sakai N, Miyake T, Sagara A, Shinozaki Y, Kitajima S, Toyama T, Hara A, Iwata Y, Shimizu M, Furuichi K, Imamura R, Suda T, Kaneko S, Wada T.

Ther Apher Dial. 2018 Jan 10. doi: 10.1111/1744-9987.12651. [Epub ahead of print]

PMID:
29318737
19.

ER Stress Signaling Promotes the Survival of Cancer "Persister Cells" Tolerant to EGFR Tyrosine Kinase Inhibitors.

Terai H, Kitajima S, Potter DS, Matsui Y, Quiceno LG, Chen T, Kim TJ, Rusan M, Thai TC, Piccioni F, Donovan KA, Kwiatkowski N, Hinohara K, Wei G, Gray NS, Fischer ES, Wong KK, Shimamura T, Letai A, Hammerman PS, Barbie DA.

Cancer Res. 2018 Feb 15;78(4):1044-1057. doi: 10.1158/0008-5472.CAN-17-1904. Epub 2017 Dec 19.

PMID:
29259014
20.

Cloning and Aggregation Characterization of Rubber Elongation Factor and Small Rubber Particle Protein from Ficus carica.

Yokota S, Suzuki Y, Saitoh K, Kitajima S, Ohya N, Gotoh T.

Mol Biotechnol. 2018 Feb;60(2):83-91. doi: 10.1007/s12033-017-0051-6.

PMID:
29214498
21.

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, He MX, Walker W, Zhang G, Tian T, Cheng C, Wei Z, Palakurthi S, Bittinger M, Vitzthum H, Kim JW, Merlino A, Quinn M, Venkataramani C, Kaplan JA, Portell A, Gokhale PC, Phillips B, Smart A, Rotem A, Jones RE, Keogh L, Anguiano M, Stapleton L, Jia Z, Barzily-Rokni M, Cañadas I, Thai TC, Hammond MR, Vlahos R, Wang ES, Zhang H, Li S, Hanna GJ, Huang W, Hoang MP, Piris A, Eliane JP, Stemmer-Rachamimov AO, Cameron L, Su MJ, Shah P, Izar B, Thakuria M, LeBoeuf NR, Rabinowits G, Gunda V, Parangi S, Cleary JM, Miller BC, Kitajima S, Thummalapalli R, Miao B, Barbie TU, Sivathanu V, Wong J, Richards WG, Bueno R, Yoon CH, Miret J, Herlyn M, Garraway LA, Van Allen EM, Freeman GJ, Kirschmeier PT, Lorch JH, Ott PA, Hodi FS, Flaherty KT, Kamm RD, Boland GM, Wong KK, Dornan D, Paweletz CP, Barbie DA.

Cancer Discov. 2018 Feb;8(2):196-215. doi: 10.1158/2159-8290.CD-17-0833. Epub 2017 Nov 3.

PMID:
29101162
22.

Decline in estimated glomerular filtration rate is associated with risk of end-stage renal disease in type 2 diabetes with macroalbuminuria: an observational study from JDNCS.

Shimizu M, Furuichi K, Toyama T, Funamoto T, Kitajima S, Hara A, Ogawa D, Koya D, Ikeda K, Koshino Y, Kurokawa Y, Abe H, Mori K, Nakayama M, Konishi Y, Samejima KI, Matsui M, Yamauchi H, Gohda T, Fukami K, Nagata D, Yamazaki H, Yuzawa Y, Suzuki Y, Fujimoto S, Maruyama S, Kato S, Naito T, Yoshimura K, Yokoyama H, Wada T; Research Group of Diabetic Nephropathy, the Ministry of Health, Labour, and Welfare of Japan and Japan Agency for Medical Research and Development.

Clin Exp Nephrol. 2018 Apr;22(2):377-387. doi: 10.1007/s10157-017-1467-9. Epub 2017 Sep 9.

PMID:
28889347
23.

Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation.

Kitajima S, Takahashi C.

Cancer Sci. 2017 Sep;108(9):1726-1731. doi: 10.1111/cas.13312. Epub 2017 Jul 29. Review.

24.

Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.

Kim JW, Abudayyeh OO, Yeerna H, Yeang CH, Stewart M, Jenkins RW, Kitajima S, Konieczkowski DJ, Medetgul-Ernar K, Cavazos T, Mah C, Ting S, Van Allen EM, Cohen O, Mcdermott J, Damato E, Aguirre AJ, Liang J, Liberzon A, Alexe G, Doench J, Ghandi M, Vazquez F, Weir BA, Tsherniak A, Subramanian A, Meneses-Cime K, Park J, Clemons P, Garraway LA, Thomas D, Boehm JS, Barbie DA, Hahn WC, Mesirov JP, Tamayo P.

Cell Syst. 2017 Aug 23;5(2):105-118.e9. doi: 10.1016/j.cels.2017.08.002.

25.

ATF3 negatively regulates cellular antiviral signaling and autophagy in the absence of type I interferons.

Sood V, Sharma KB, Gupta V, Saha D, Dhapola P, Sharma M, Sen U, Kitajima S, Chowdhury S, Kalia M, Vrati S.

Sci Rep. 2017 Aug 18;7(1):8789. doi: 10.1038/s41598-017-08584-9.

26.

The novel heme-dependent inducible protein, SRRD regulates heme biosynthesis and circadian rhythms.

Adachi Y, Umeda M, Kawazoe A, Sato T, Ohkawa Y, Kitajima S, Izawa S, Sagami I, Taketani S.

Arch Biochem Biophys. 2017 Oct 1;631:19-29. doi: 10.1016/j.abb.2017.08.006. Epub 2017 Aug 9.

PMID:
28802827
27.

Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression.

Sun W, Kato H, Kitajima S, Lee KL, Gradin K, Okamoto T, Poellinger L.

Sci Rep. 2017 Aug 3;7(1):7190. doi: 10.1038/s41598-017-05685-3. Erratum in: Sci Rep. 2018 Jul 20;8(1):11239.

28.

Impairment of the carnitine/organic cation transporter 1-ergothioneine axis is mediated by intestinal transporter dysfunction in chronic kidney disease.

Shinozaki Y, Furuichi K, Toyama T, Kitajima S, Hara A, Iwata Y, Sakai N, Shimizu M, Kaneko S, Isozumi N, Nagamori S, Kanai Y, Sugiura T, Kato Y, Wada T.

Kidney Int. 2017 Dec;92(6):1356-1369. doi: 10.1016/j.kint.2017.04.032. Epub 2017 Jul 26.

PMID:
28754554
29.

Inhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesis.

Sakai N, Nakamura M, Lipson KE, Miyake T, Kamikawa Y, Sagara A, Shinozaki Y, Kitajima S, Toyama T, Hara A, Iwata Y, Shimizu M, Furuichi K, Kaneko S, Tager AM, Wada T.

Sci Rep. 2017 Jul 14;7(1):5392. doi: 10.1038/s41598-017-05624-2.

30.

A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling.

Muranaka H, Hayashi A, Minami K, Kitajima S, Kohno S, Nishimoto Y, Nagatani N, Suzuki M, Kulathunga LAN, Sasaki N, Okada N, Matsuzaka T, Shimano H, Tada H, Takahashi C.

Oncogenesis. 2017 Jun 26;6(6):e350. doi: 10.1038/oncsis.2017.51.

31.

Superior canal dehiscence syndrome associated with scuba diving.

Kitajima N, Sugita-Kitajima A, Kitajima S.

Diving Hyperb Med. 2017 Jun;47(2):123-126.

32.

Increased Hepatic Expression of Endothelial Lipase Inhibits Cholesterol Diet-Induced Hypercholesterolemia and Atherosclerosis in Transgenic Rabbits.

Wang C, Nishijima K, Kitajima S, Niimi M, Yan H, Chen Y, Ning B, Matsuhisa F, Liu E, Zhang J, Chen YE, Fan J.

Arterioscler Thromb Vasc Biol. 2017 Jul;37(7):1282-1289. doi: 10.1161/ATVBAHA.117.309139. Epub 2017 May 25.

33.

An autopsy case of vertebrobasilar dolichoectasia under hemodialysis due to autosomal dominant polycystic kidney disease.

Nakagawa S, Furuichi K, Sagara A, Shinozaki Y, Kitajima S, Toyama T, Hara A, Iwata Y, Sakai N, Shimizu M, Matsui K, Kaneko S, Toyama T, Wada T.

CEN Case Rep. 2016 May;5(1):51-55. doi: 10.1007/s13730-015-0190-1. Epub 2015 Aug 18.

34.

Ferritin 2 domain-containing protein found in lacquer tree (Toxicodendron vernicifluum) sap has negative effects on laccase and peroxidase reactions.

Kitajima S, Imamura T, Iibushi J, Ikenaga M, Tachibana Y, Andoh N, Oyabu H, Hirooka K, Shiina T, Ishizaki Y.

Biosci Biotechnol Biochem. 2017 Jun;81(6):1165-1175. doi: 10.1080/09168451.2017.1289814. Epub 2017 Feb 10.

PMID:
28485213
35.

The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.

Kitajima S, Yoshida A, Kohno S, Li F, Suzuki S, Nagatani N, Nishimoto Y, Sasaki N, Muranaka H, Wan Y, Thai TC, Okahashi N, Matsuda F, Shimizu H, Nishiuchi T, Suzuki Y, Tominaga K, Gotoh N, Suzuki M, Ewen ME, Barbie DA, Hirose O, Tanaka T, Takahashi C.

Oncogene. 2017 Sep 7;36(36):5145-5157. doi: 10.1038/onc.2017.124. Epub 2017 May 8.

PMID:
28481867
36.

Down-regulation of the two-component system and cell-wall biosynthesis-related genes was associated with the reversion to daptomycin susceptibility in daptomycin non-susceptible methicillin-resistant Staphylococcus aureus.

Iwata Y, Satou K, Tsuzuku H, Furuichi K, Senda Y, Sakai-Takemori Y, Wada T, Fujita S, Miyake T, Yasuda H, Sakai N, Kitajima S, Toyama T, Shinozaki Y, Sagara A, Miyagawa T, Hara A, Shimizu M, Kamikawa Y, Kaneko S, Wada T.

Eur J Clin Microbiol Infect Dis. 2017 Oct;36(10):1839-1845. doi: 10.1007/s10096-017-2999-3. Epub 2017 May 5.

PMID:
28477235
37.

Yb<sup>3+</sup>-doped CaF<sub>2</sub>-LaF<sub>3</sub> ceramics laser.

Kitajima S, Yamakado K, Shirakawa A, Ueda KI, Ezura Y, Ishizawa H.

Opt Lett. 2017 May 1;42(9):1724-1727. doi: 10.1364/OL.42.001724.

PMID:
28454145
38.

[A Case of Giant Prostate Carcinoma Effectively Treated with External-Beam Radiation Therapy].

Kanda S, Narita S, Komine N, Kitajima S, Yamauchi M, Sugita A, Saito Y, Habuchi T.

Hinyokika Kiyo. 2016 Dec;62(12):647-650. doi: 10.14989/ActaUrolJap_62_12_647. Japanese.

39.

MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6.

Yoshida A, Kitajima S, Li F, Cheng C, Takegami Y, Kohno S, Wan YS, Hayashi N, Muranaka H, Nishimoto Y, Nagatani N, Nishiuchi T, Thai TC, Suzuki S, Nakao S, Tanaka T, Hirose O, Barbie DA, Takahashi C.

Oncotarget. 2017 Feb 21;8(8):13872-13885. doi: 10.18632/oncotarget.14681.

40.

Transcriptome and proteome analyses provide insight into laticifer's defense of Euphorbia tirucalli against pests.

Kitajima S, Miura K, Aoki W, Yamato KT, Taira T, Murakami R, Aburaya S.

Plant Physiol Biochem. 2016 Nov;108:434-446. doi: 10.1016/j.plaphy.2016.08.008. Epub 2016 Aug 18.

PMID:
27566924
41.

Kerr-lens mode-locked Yb<sup>3+</sup>-doped Lu<sub>3</sub>Al<sub>5</sub>O<sub>12</sub> ceramic laser.

Kitajima S, Nakao H, Shirakawa A, Yagi H, Yanagitani T.

Opt Lett. 2016 Oct 1;41(19):4570-4573. doi: 10.1364/OL.41.004570.

PMID:
27749883
42.

Acrolein-detoxifying isozymes of glutathione transferase in plants.

Mano J, Ishibashi A, Muneuchi H, Morita C, Sakai H, Biswas MS, Koeduka T, Kitajima S.

Planta. 2017 Feb;245(2):255-264. doi: 10.1007/s00425-016-2604-5. Epub 2016 Oct 7.

PMID:
27718072
43.

Expansion of medical vocabularies using distributional semantics on Japanese patient blogs.

Ahltorp M, Skeppstedt M, Kitajima S, Henriksson A, Rzepka R, Araki K.

J Biomed Semantics. 2016 Sep 26;7(1):58.

44.

Evaluation of Pulmonary Toxicity of Zinc Oxide Nanoparticles Following Inhalation and Intratracheal Instillation.

Morimoto Y, Izumi H, Yoshiura Y, Tomonaga T, Oyabu T, Myojo T, Kawai K, Yatera K, Shimada M, Kubo M, Yamamoto K, Kitajima S, Kuroda E, Kawaguchi K, Sasaki T.

Int J Mol Sci. 2016 Aug 1;17(8). pii: E1241. doi: 10.3390/ijms17081241.

45.

Learning and Memory Deficits in Male Adult Mice Treated with a Benzodiazepine Sleep-Inducing Drug during the Juvenile Period.

Furukawa Y, Tanemura K, Igarashi K, Ideta-Otsuka M, Aisaki K, Kitajima S, Kitagawa M, Kanno J.

Front Neurosci. 2016 Jul 20;10:339. doi: 10.3389/fnins.2016.00339. eCollection 2016.

46.

[Control of undifferentiated state by RB tumor suppressor].

Kohno S, Kitajima S, Sasaki N, Takahashi C.

Seikagaku. 2016 Jun;88(3):335-41. Japanese. No abstract available.

PMID:
27483952
47.

ATF3 controls proliferation of osteoclast precursor and bone remodeling.

Fukasawa K, Park G, Iezaki T, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Yoneda Y, Takarada T, Kitajima S, Vacher J, Hinoi E.

Sci Rep. 2016 Aug 2;6:30918. doi: 10.1038/srep30918.

48.

Prioritized Expression of BDH2 under Bulk Translational Repression and Its Contribution to Tolerance to Severe Vanillin Stress in Saccharomyces cerevisiae.

Ishida Y, Nguyen TT, Kitajima S, Izawa S.

Front Microbiol. 2016 Jul 6;7:1059. doi: 10.3389/fmicb.2016.01059. eCollection 2016.

49.

Quantitative analysis of inner-ear barotrauma using a Eustachian tube function analyzer.

Kitajima N, Sugita-Kitajima A, Kitajima S.

Diving Hyperb Med. 2016 Jun;46(2):76-81.

PMID:
27334994
50.

Inflammation as a driver and vulnerability of KRAS mediated oncogenesis.

Kitajima S, Thummalapalli R, Barbie DA.

Semin Cell Dev Biol. 2016 Oct;58:127-35. doi: 10.1016/j.semcdb.2016.06.009. Epub 2016 Jun 11. Review.

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