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Items: 1 to 50 of 149

1.

Therapeutic potential of adenovirus-mediated TFF2-CTP-Flag peptide for treatment of colorectal cancer.

Dubeykovskaya ZA, Duddempudi PK, Deng H, Valenti G, Cuti KL, Nagar K, Tailor Y, Guha C, Kitajewski J, Wang TC.

Cancer Gene Ther. 2018 Jul 25. doi: 10.1038/s41417-018-0036-z. [Epub ahead of print]

PMID:
30042499
2.

Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence.

Kim YM, Youn SW, Sudhahar V, Das A, Chandhri R, Cuervo Grajal H, Kweon J, Leanhart S, He L, Toth PT, Kitajewski J, Rehman J, Yoon Y, Cho J, Fukai T, Ushio-Fukai M.

Cell Rep. 2018 Jun 19;23(12):3565-3578. doi: 10.1016/j.celrep.2018.05.054.

3.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 May 15. doi: 10.1007/s10456-018-9613-x. [Epub ahead of print] Review.

4.

NOTCH3 regulates stem-to-mural cell differentiation in infantile hemangioma.

Edwards AK, Glithero K, Grzesik P, Kitajewski AA, Munabi NC, Hardy K, Tan QK, Schonning M, Kangsamaksin T, Kitajewski JK, Shawber CJ, Wu JK.

JCI Insight. 2017 Nov 2;2(21). pii: 93764. doi: 10.1172/jci.insight.93764. [Epub ahead of print]

5.

PDGFRβ-P2A-CreERT2 mice: a genetic tool to target pericytes in angiogenesis.

Cuervo H, Pereira B, Nadeem T, Lin M, Lee F, Kitajewski J, Lin CS.

Angiogenesis. 2017 Nov;20(4):655-662. doi: 10.1007/s10456-017-9570-9. Epub 2017 Jul 27.

PMID:
28752390
6.

Dynamic maternal and fetal Notch activity and expression in placentation.

Levin HI, Sullivan-Pyke CS, Papaioannou VE, Wapner RJ, Kitajewski JK, Shawber CJ, Douglas NC.

Placenta. 2017 Jul;55:5-12. doi: 10.1016/j.placenta.2017.04.014. Epub 2017 Apr 21.

7.

Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts.

Werth M, Schmidt-Ott KM, Leete T, Qiu A, Hinze C, Viltard M, Paragas N, Shawber CJ, Yu W, Lee P, Chen X, Sarkar A, Mu W, Rittenberg A, Lin CS, Kitajewski J, Al-Awqati Q, Barasch J.

Elife. 2017 Jun 3;6. pii: e24265. doi: 10.7554/eLife.24265.

8.

Leukotriene B4 antagonism ameliorates experimental lymphedema.

Tian W, Rockson SG, Jiang X, Kim J, Begaye A, Shuffle EM, Tu AB, Cribb M, Nepiyushchikh Z, Feroze AH, Zamanian RT, Dhillon GS, Voelkel NF, Peters-Golden M, Kitajewski J, Dixon JB, Nicolls MR.

Sci Transl Med. 2017 May 10;9(389). pii: eaal3920. doi: 10.1126/scitranslmed.aal3920.

PMID:
28490670
9.

Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis.

Poulos MG, Ramalingam P, Gutkin MC, Kleppe M, Ginsberg M, Crowley MJ, Elemento O, Levine RL, Rafii S, Kitajewski J, Greenblatt MB, Shim JH, Butler JM.

Nat Commun. 2016 Dec 21;7:13829. doi: 10.1038/ncomms13829.

10.

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice.

Westerterp M, Tsuchiya K, Tattersall IW, Fotakis P, Bochem AE, Molusky MM, Ntonga V, Abramowicz S, Parks JS, Welch CL, Kitajewski J, Accili D, Tall AR.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1328-37. doi: 10.1161/ATVBAHA.115.306670. Epub 2016 May 19.

11.

A new paradigm for the role of smooth muscle cells in the human cervix.

Vink JY, Qin S, Brock CO, Zork NM, Feltovich HM, Chen X, Urie P, Myers KM, Hall TJ, Wapner R, Kitajewski JK, Shawber CJ, Gallos G.

Am J Obstet Gynecol. 2016 Oct;215(4):478.e1-478.e11. doi: 10.1016/j.ajog.2016.04.053. Epub 2016 May 7.

PMID:
27166013
12.

In vitro modeling of endothelial interaction with macrophages and pericytes demonstrates Notch signaling function in the vascular microenvironment.

Tattersall IW, Du J, Cong Z, Cho BS, Klein AM, Dieck CL, Chaudhri RA, Cuervo H, Herts JH, Kitajewski J.

Angiogenesis. 2016 Apr;19(2):201-15. doi: 10.1007/s10456-016-9501-1. Epub 2016 Mar 10.

13.

Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer.

Dubeykovskaya Z, Si Y, Chen X, Worthley DL, Renz BW, Urbanska AM, Hayakawa Y, Xu T, Westphalen CB, Dubeykovskiy A, Chen D, Friedman RA, Asfaha S, Nagar K, Tailor Y, Muthupalani S, Fox JG, Kitajewski J, Wang TC.

Nat Commun. 2016 Feb 4;7:10517. doi: 10.1038/ncomms10517.

14.

Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β.

Verginelli F, Adesso L, Limon I, Alisi A, Gueguen M, Panera N, Giorda E, Raimondi L, Ciarapica R, Campese AF, Screpanti I, Stifani S, Kitajewski J, Miele L, Rota R, Locatelli F.

Oncotarget. 2015 Dec 22;6(41):43216-29. doi: 10.18632/oncotarget.6456.

15.

Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus.

Shawber CJ, Lin L, Gnarra M, Sauer MV, Papaioannou VE, Kitajewski JK, Douglas NC.

Vasc Cell. 2015 Dec 1;7:9. doi: 10.1186/s13221-015-0034-y. eCollection 2015.

16.

Propranolol Targets Hemangioma Stem Cells via cAMP and Mitogen-Activated Protein Kinase Regulation.

Munabi NC, England RW, Edwards AK, Kitajewski AA, Tan QK, Weinstein A, Kung JE, Wilcox M, Kitajewski JK, Shawber CJ, Wu JK.

Stem Cells Transl Med. 2016 Jan;5(1):45-55. doi: 10.5966/sctm.2015-0076. Epub 2015 Nov 16.

17.

Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations.

Kofler NM, Cuervo H, Uh MK, Murtomäki A, Kitajewski J.

Sci Rep. 2015 Nov 13;5:16449. doi: 10.1038/srep16449.

18.

Pericytes are progenitors for coronary artery smooth muscle.

Volz KS, Jacobs AH, Chen HI, Poduri A, McKay AS, Riordan DP, Kofler N, Kitajewski J, Weissman I, Red-Horse K.

Elife. 2015 Oct 19;4. pii: e10036. doi: 10.7554/eLife.10036.

19.

Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.

Qiu W, Tang SM, Lee S, Turk AT, Sireci AN, Qiu A, Rose C, Xie C, Kitajewski J, Wen HJ, Crawford HC, Sims PA, Hruban RH, Remotti HE, Su GH.

Gastroenterology. 2016 Jan;150(1):218-228.e12. doi: 10.1053/j.gastro.2015.09.013. Epub 2015 Sep 25.

20.

Notch suppresses angiogenesis and progression of hepatic metastases.

Banerjee D, Hernandez SL, Garcia A, Kangsamaksin T, Sbiroli E, Andrews J, Forrester LA, Wei N, Kadenhe-Chiweshe A, Shawber CJ, Kitajewski JK, Kandel JJ, Yamashiro DJ.

Cancer Res. 2015 Apr 15;75(8):1592-602. doi: 10.1158/0008-5472.CAN-14-1493. Epub 2015 Mar 5.

21.

Notch functions in developmental and tumour angiogenesis by diverse mechanisms.

Kangsamaksin T, Tattersall IW, Kitajewski J.

Biochem Soc Trans. 2014 Dec;42(6):1563-8. doi: 10.1042/BST20140233. Review.

PMID:
25399571
22.

NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth.

Kangsamaksin T, Murtomaki A, Kofler NM, Cuervo H, Chaudhri RA, Tattersall IW, Rosenstiel PE, Shawber CJ, Kitajewski J.

Cancer Discov. 2015 Feb;5(2):182-97. doi: 10.1158/2159-8290.CD-14-0650. Epub 2014 Nov 11.

23.

A systematic evaluation of collagen cross-links in the human cervix.

Zork NM, Myers KM, Yoshida K, Cremers S, Jiang H, Ananth CV, Wapner RJ, Kitajewski J, Vink J.

Am J Obstet Gynecol. 2015 Mar;212(3):321.e1-8. doi: 10.1016/j.ajog.2014.09.036. Epub 2014 Oct 2.

24.

A selective microRNA-based strategy inhibits restenosis while preserving endothelial function.

Santulli G, Wronska A, Uryu K, Diacovo TG, Gao M, Marx SO, Kitajewski J, Chilton JM, Akat KM, Tuschl T, Marks AR, Totary-Jain H.

J Clin Invest. 2014 Sep;124(9):4102-14. doi: 10.1172/JCI76069. Epub 2014 Aug 18.

25.

Propranolol promotes accelerated and dysregulated adipogenesis in hemangioma stem cells.

England RW, Hardy KL, Kitajewski AM, Wong A, Kitajewski JK, Shawber CJ, Wu JK.

Ann Plast Surg. 2014 Sep;73 Suppl 1:S119-24. doi: 10.1097/SAP.0000000000000272.

26.

VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment.

Douglas NC, Zimmermann RC, Tan QK, Sullivan-Pyke CS, Sauer MV, Kitajewski JK, Shawber CJ.

Vasc Cell. 2014 Aug 1;6:16. doi: 10.1186/2045-824X-6-16. eCollection 2014.

27.

Notch signaling functions in lymphatic valve formation.

Murtomaki A, Uh MK, Kitajewski C, Zhao J, Nagasaki T, Shawber CJ, Kitajewski J.

Development. 2014 Jun;141(12):2446-51. doi: 10.1242/dev.101188.

28.

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.

Rhim AD, Oberstein PE, Thomas DH, Mirek ET, Palermo CF, Sastra SA, Dekleva EN, Saunders T, Becerra CP, Tattersall IW, Westphalen CB, Kitajewski J, Fernandez-Barrena MG, Fernandez-Zapico ME, Iacobuzio-Donahue C, Olive KP, Stanger BZ.

Cancer Cell. 2014 Jun 16;25(6):735-47. doi: 10.1016/j.ccr.2014.04.021. Epub 2014 May 22.

29.

NOTCH2 expression is decreased in epithelial ovarian cancer and is related to the tumor histological subtype.

Galic V, Shawber CJ, Reeves C, Shah M, Murtomaki A, Wright J, Herzog T, Tong GX, Kitajewski J.

Pathol Discov. 2013 Aug 16;1:4.

30.

Abstract 70: Propranolol Effects on Hemangiomas are Mediated via Distinct Pathways.

England RW, Munabi NC, Glithero KJ, Kitajewski A, Kitajewski J, Shawber CJ, Wu JK.

Plast Reconstr Surg. 2014 Mar;133(3 Suppl):81-2. doi: 10.1097/01.prs.0000445103.16503.19. No abstract available.

PMID:
25942181
31.

Abstract 3: propranolol accelerates involution in a murine model of infantile hemangioma.

Munabi NC, England RW, Glithero KJ, Chang MM, Kitajewski A, Kitajewski JK, Shawber CJ, Wu JK.

Plast Reconstr Surg. 2014 Mar;133(3 Suppl):11. doi: 10.1097/01.prs.0000444916.92464.71. No abstract available.

PMID:
25942114
32.

Abstract 2: NOTCH3 Regulates Mural Cell Differentiation of HemSCs.

Glithero KJ, Munabi NC, England RW, Kitajewski A, Chang M, Kitajewski JK, Shawber CJ, Wu JK.

Plast Reconstr Surg. 2014 Mar;133(3 Suppl):11. doi: 10.1097/01.prs.0000444915.15335.22. No abstract available.

PMID:
25942113
33.

Cervical collagen network remodeling in normal pregnancy and disrupted parturition in Antxr2 deficient mice.

Yoshida K, Reeves C, Vink J, Kitajewski J, Wapner R, Jiang H, Cremers S, Myers K.

J Biomech Eng. 2014 Feb;136(2):021017. doi: 10.1115/1.4026423.

34.

Delta-like ligand 4 regulates vascular endothelial growth factor receptor 2-driven luteal angiogenesis through induction of a tip/stalk phenotype in proliferating endothelial cells.

García-Pascual CM, Zimmermann RC, Ferrero H, Shawber CJ, Kitajewski J, Simón C, Pellicer A, Gómez R.

Fertil Steril. 2013 Dec;100(6):1768-76.e1. doi: 10.1016/j.fertnstert.2013.08.034. Epub 2013 Sep 26.

PMID:
24074756
35.

Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis.

Hernandez SL, Banerjee D, Garcia A, Kangsamaksin T, Cheng WY, Anastassiou D, Funahashi Y, Kadenhe-Chiweshe A, Shawber CJ, Kitajewski JK, Kandel JJ, Yamashiro DJ.

Vasc Cell. 2013 Sep 25;5(1):17. doi: 10.1186/2045-824X-5-17.

36.

Anthrax toxin receptor 2 promotes human uterine smooth muscle cell viability, migration and contractility.

Vink JY, Charles-Horvath PC, Kitajewski JK, Reeves CV.

Am J Obstet Gynecol. 2014 Feb;210(2):154.e1-8. doi: 10.1016/j.ajog.2013.09.030. Epub 2013 Sep 20.

37.

Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis.

Poulos MG, Guo P, Kofler NM, Pinho S, Gutkin MC, Tikhonova A, Aifantis I, Frenette PS, Kitajewski J, Rafii S, Butler JM.

Cell Rep. 2013 Sep 12;4(5):1022-34. doi: 10.1016/j.celrep.2013.07.048. Epub 2013 Sep 5.

38.

Lymphatics in health and disease: a new thematic series in vascular cell.

Kitajewski J, Shawber CJ, Simons M.

Vasc Cell. 2013 Jul 25;5(1):14. doi: 10.1186/2045-824X-5-14.

39.

Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.

Pajvani UB, Qiang L, Kangsamaksin T, Kitajewski J, Ginsberg HN, Accili D.

Nat Med. 2013 Aug;19(8):1054-60. doi: 10.1038/nm.3259. Epub 2013 Jul 7.

40.

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

Jovanovic VP, Sauer CM, Shawber CJ, Gomez R, Wang X, Sauer MV, Kitajewski J, Zimmermann RC.

Reprod Biol Endocrinol. 2013 May 15;11:43. doi: 10.1186/1477-7827-11-43.

41.

Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium.

Murtomaki A, Uh MK, Choi YK, Kitajewski C, Borisenko V, Kitajewski J, Shawber CJ.

Development. 2013 Jun;140(11):2365-76. doi: 10.1242/dev.083865. Epub 2013 Apr 24.

42.

Wnts heal by restraining angiogenesis.

Kitajewski J.

Blood. 2013 Mar 28;121(13):2381-2. doi: 10.1182/blood-2013-01-479063. No abstract available.

43.

The role of Notch and gamma-secretase inhibition in an ovarian cancer model.

Shah MM, Zerlin M, Li BY, Herzog TJ, Kitajewski JK, Wright JD.

Anticancer Res. 2013 Mar;33(3):801-8.

44.

Studies in mice reveal a role for anthrax toxin receptors in matrix metalloproteinase function and extracellular matrix homeostasis.

Reeves C, Charles-Horvath P, Kitajewski J.

Toxins (Basel). 2013 Feb 6;5(2):315-26. doi: 10.3390/toxins5020315. Review.

45.

Evaluating tumor angiogenesis.

Uh MK, Kandel J, Kitajewski J.

Methods Mol Biol. 2013;980:341-51. doi: 10.1007/978-1-62703-287-2_20.

PMID:
23359165
46.

Propranolol accelerates adipogenesis in hemangioma stem cells and causes apoptosis of hemangioma endothelial cells.

Wong A, Hardy KL, Kitajewski AM, Shawber CJ, Kitajewski JK, Wu JK.

Plast Reconstr Surg. 2012 Nov;130(5):1012-21. doi: 10.1097/PRS.0b013e318267d3db.

47.

"Large eaters" meet blood vessels: a new thematic series on macrophages and angiogenesis.

Kitajewski J.

Vasc Cell. 2012 Oct 22;4(1):17. doi: 10.1186/2045-824X-4-17.

48.

Notch signaling in developmental and tumor angiogenesis.

Kofler NM, Shawber CJ, Kangsamaksin T, Reed HO, Galatioto J, Kitajewski J.

Genes Cancer. 2011 Dec;2(12):1106-16. doi: 10.1177/1947601911423030.

49.

Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.

Xu H, Zhu J, Smith S, Foldi J, Zhao B, Chung AY, Outtz H, Kitajewski J, Shi C, Weber S, Saftig P, Li Y, Ozato K, Blobel CP, Ivashkiv LB, Hu X.

Nat Immunol. 2012 May 20;13(7):642-50. doi: 10.1038/ni.2304.

50.

Anthrax toxin receptor 2 functions in ECM homeostasis of the murine reproductive tract and promotes MMP activity.

Reeves CV, Wang X, Charles-Horvath PC, Vink JY, Borisenko VY, Young JA, Kitajewski JK.

PLoS One. 2012;7(4):e34862. doi: 10.1371/journal.pone.0034862. Epub 2012 Apr 17.

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