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Items: 22

1.

Airway Innervation and Plasticity in Asthma.

Kistemaker LEM, Prakash YS.

Physiology (Bethesda). 2019 Jul 1;34(4):283-298. doi: 10.1152/physiol.00050.2018.

PMID:
31165683
2.

Second M3 muscarinic receptor binding site contributes to bronchoprotection by tiotropium.

Kistemaker LEM, Elzinga CRS, Tautermann CS, Pieper MP, Seeliger D, Alikhil S, Schmidt M, Meurs H, Gosens R.

Br J Pharmacol. 2019 Aug;176(16):2864-2876. doi: 10.1111/bph.14707. Epub 2019 Jul 2.

PMID:
31077341
3.

Mouse Lung Tissue Slice Culture.

Wu X, van Dijk EM, Bos IST, Kistemaker LEM, Gosens R.

Methods Mol Biol. 2019;1940:297-311. doi: 10.1007/978-1-4939-9086-3_21.

PMID:
30788834
4.

Cigarette smoke up-regulates PDE3 and PDE4 to decrease cAMP in airway cells.

Zuo H, Han B, Poppinga WJ, Ringnalda L, Kistemaker LEM, Halayko AJ, Gosens R, Nikolaev VO, Schmidt M.

Br J Pharmacol. 2018 Jul;175(14):2988-3006. doi: 10.1111/bph.14347. Epub 2018 Jun 3.

5.

Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells.

Mertens TCJ, van der Does AM, Kistemaker LE, Ninaber DK, Taube C, Hiemstra PS.

Physiol Rep. 2017 Jul;5(13). pii: e13347. doi: 10.14814/phy2.13347. Epub 2017 Jul 11.

6.

The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices.

Kistemaker LEM, Oenema TA, Baarsma HA, Bos IST, Schmidt M, Facchinetti F, Civelli M, Villetti G, Gosens R.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L507-L515. doi: 10.1152/ajplung.00069.2017. Epub 2017 Jun 8.

7.

Aberrant DNA methylation and expression of SPDEF and FOXA2 in airway epithelium of patients with COPD.

Song J, Heijink IH, Kistemaker LEM, Reinders-Luinge M, Kooistra W, Noordhoek JA, Gosens R, Brandsma CA, Timens W, Hiemstra PS, Rots MG, Hylkema MN.

Clin Epigenetics. 2017 Apr 24;9:42. doi: 10.1186/s13148-017-0341-7. eCollection 2017.

8.

HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice.

Leus NG, van den Bosch T, van der Wouden PE, Krist K, Ourailidou ME, Eleftheriadis N, Kistemaker LE, Bos S, Gjaltema RA, Mekonnen SA, Bischoff R, Gosens R, Haisma HJ, Dekker FJ.

Sci Rep. 2017 Mar 27;7:45047. doi: 10.1038/srep45047.

9.

Corrigendum: Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice.

Hiorns JE, Bidan CM, Jensen OE, Gosens R, Kistemaker LE, Fredberg JJ, Butler JP, Krishnan R, Brook BS.

Front Physiol. 2017 Feb 28;8:117. doi: 10.3389/fphys.2017.00117. eCollection 2017.

10.

Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice.

Hiorns JE, Bidan CM, Jensen OE, Gosens R, Kistemaker LE, Fredberg JJ, Butler JP, Krishnan R, Brook BS.

Front Physiol. 2016 Jul 21;7:309. doi: 10.3389/fphys.2016.00309. eCollection 2016. Erratum in: Front Physiol. 2017 Feb 28;8:117.

11.

HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity.

Leus NG, van der Wouden PE, van den Bosch T, Hooghiemstra WTR, Ourailidou ME, Kistemaker LE, Bischoff R, Gosens R, Haisma HJ, Dekker FJ.

Biochem Pharmacol. 2016 May 15;108:58-74. doi: 10.1016/j.bcp.2016.03.010. Epub 2016 Mar 16.

12.

Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma.

Kistemaker LE, Bos IS, Menzen MH, Maarsingh H, Meurs H, Gosens R.

Respir Res. 2016 Feb 4;17:13. doi: 10.1186/s12931-016-0327-6.

13.

Anti-inflammatory effects of targeted lung denervation in patients with COPD.

Kistemaker LE, Slebos DJ, Meurs H, Kerstjens HA, Gosens R.

Eur Respir J. 2015 Nov;46(5):1489-92. doi: 10.1183/13993003.00413-2015. Epub 2015 Sep 4. No abstract available.

14.

Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells.

Kistemaker LE, Hiemstra PS, Bos IS, Bouwman S, van den Berge M, Hylkema MN, Meurs H, Kerstjens HA, Gosens R.

Thorax. 2015 Jul;70(7):668-76. doi: 10.1136/thoraxjnl-2014-205731. Epub 2015 May 20.

PMID:
25995156
15.

Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling.

Kistemaker LE, Gosens R.

Trends Pharmacol Sci. 2015 Mar;36(3):164-71. doi: 10.1016/j.tips.2014.11.005. Epub 2014 Dec 13. Review.

PMID:
25511176
16.

Muscarinic M3 receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice.

Kistemaker LE, van Os RP, Dethmers-Ausema A, Bos IS, Hylkema MN, van den Berge M, Hiemstra PS, Wess J, Meurs H, Kerstjens HA, Gosens R.

Am J Physiol Lung Cell Mol Physiol. 2015 Jan 1;308(1):L96-103. doi: 10.1152/ajplung.00259.2014. Epub 2014 Nov 7.

17.

Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling.

Noble PB, Pascoe CD, Lan B, Ito S, Kistemaker LE, Tatler AL, Pera T, Brook BS, Gosens R, West AR.

Pulm Pharmacol Ther. 2014 Dec;29(2):96-107. doi: 10.1016/j.pupt.2014.07.005. Epub 2014 Jul 23. Review.

PMID:
25062835
18.

Muscarinic M₃ receptors contribute to allergen-induced airway remodeling in mice.

Kistemaker LE, Bos ST, Mudde WM, Hylkema MN, Hiemstra PS, Wess J, Meurs H, Kerstjens HA, Gosens R.

Am J Respir Cell Mol Biol. 2014 Apr;50(4):690-8. doi: 10.1165/rcmb.2013-0220OC.

PMID:
24156289
19.

A new perspective on muscarinic receptor antagonism in obstructive airways diseases.

Meurs H, Oenema TA, Kistemaker LE, Gosens R.

Curr Opin Pharmacol. 2013 Jun;13(3):316-23. doi: 10.1016/j.coph.2013.04.004. Epub 2013 May 3. Review.

PMID:
23643733
20.

Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice.

Kistemaker LE, Bos IS, Hylkema MN, Nawijn MC, Hiemstra PS, Wess J, Meurs H, Kerstjens HA, Gosens R.

Eur Respir J. 2013 Dec;42(6):1677-88. doi: 10.1183/09031936.00112412. Epub 2013 Feb 8.

21.

Regulation of airway inflammation and remodeling by muscarinic receptors: perspectives on anticholinergic therapy in asthma and COPD.

Kistemaker LE, Oenema TA, Meurs H, Gosens R.

Life Sci. 2012 Nov 27;91(21-22):1126-33. doi: 10.1016/j.lfs.2012.02.021. Epub 2012 Mar 3. Review.

PMID:
22406302
22.

PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells.

Roscioni SS, Kistemaker LE, Menzen MH, Elzinga CR, Gosens R, Halayko AJ, Meurs H, Schmidt M.

Respir Res. 2009 Sep 29;10:88. doi: 10.1186/1465-9921-10-88.

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