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Items: 1 to 50 of 128

1.

Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo.

Sonzogni O, Haynes J, Seifried LA, Kamel YM, Huang K, BeGora MD, Yeung FA, Robert-Tissot C, Heng YJ, Yuan X, Wulf GM, Kron KJ, Wagenblast E, Lupien M, Kislinger T, Hannon GJ, Muthuswamy SK.

PLoS Biol. 2018 Jun 20;16(6):e2004049. doi: 10.1371/journal.pbio.2004049. eCollection 2018 Jun.

2.

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities.

Casey AE, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, Cruickshank J, Shehata M, Drysdale E, Fang H, Kim H, Isserlin R, Bailey S, Medina T, Deblois G, Shiah YJ, Barsyte-Lovejoy D, Hofer S, Bader G, Lupien M, Arrowsmith C, Knapp S, De Carvalho D, Berman H, Boutros PC, Kislinger T, Khokha R.

J Cell Biol. 2018 Aug 6;217(8):2951-2974. doi: 10.1083/jcb.201804042. Epub 2018 Jun 19.

3.

Proteomic Analysis of Cancer-Associated Fibroblasts Reveals a Paracrine Role for MFAP5 in Human Oral Tongue Squamous Cell Carcinoma.

Principe S, Mejia-Guerrero S, Ignatchenko V, Sinha A, Ignatchenko A, Shi W, Pereira K, Su S, Huang SH, O'Sullivan B, Xu W, Goldstein DP, Weinreb I, Ailles L, Liu FF, Kislinger T.

J Proteome Res. 2018 Jun 1;17(6):2045-2059. doi: 10.1021/acs.jproteome.7b00925. Epub 2018 May 2.

PMID:
29681158
4.

Cell-surface proteomics for the identification of novel therapeutic targets in cancer.

Kuhlmann L, Cummins E, Samudio I, Kislinger T.

Expert Rev Proteomics. 2018 Mar;15(3):259-275. doi: 10.1080/14789450.2018.1429924. Epub 2018 Jan 23.

PMID:
29343144
5.

Proteomic Profiling of Secreted Proteins, Exosomes, and Microvesicles in Cell Culture Conditioned Media.

Sinha A, Principe S, Alfaro J, Ignatchenko A, Ignatchenko V, Kislinger T.

Methods Mol Biol. 2018;1722:91-102. doi: 10.1007/978-1-4939-7553-2_6.

PMID:
29264800
6.

Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization.

Garnier D, Meehan B, Kislinger T, Daniel P, Sinha A, Abdulkarim B, Nakano I, Rak J.

Neuro Oncol. 2018 Jan 22;20(2):236-248. doi: 10.1093/neuonc/nox142.

PMID:
29016925
7.

Proteomic Response of Human Umbilical Vein Endothelial Cells to Histamine Stimulation.

Emirbayer PE, Sinha A, Ignatchenko V, Hoyer S, Dörrie J, Schaft N, Pischetsrieder M, Kislinger T.

Proteomics. 2017 Nov;17(21). doi: 10.1002/pmic.201700116. Epub 2017 Oct 12.

PMID:
28921918
8.

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.

Cogger KF, Sinha A, Sarangi F, McGaugh EC, Saunders D, Dorrell C, Mejia-Guerrero S, Aghazadeh Y, Rourke JL, Screaton RA, Grompe M, Streeter PR, Powers AC, Brissova M, Kislinger T, Nostro MC.

Nat Commun. 2017 Aug 24;8(1):331. doi: 10.1038/s41467-017-00561-0.

9.

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T, Liang Y, Llorente A, Lunavat TR, Maji S, Monteleone F, Øverbye A, Panaretakis T, Patel T, Peinado H, Pluchino S, Principe S, Ronquist G, Royo F, Sahoo S, Spinelli C, Stensballe A, Théry C, van Herwijnen MJC, Wauben M, Welton JL, Zhao K, Mathivanan S.

J Extracell Vesicles. 2017 May 26;6(1):1321455. doi: 10.1080/20013078.2017.1321455. eCollection 2017.

10.

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Alfaro JA, Ignatchenko A, Ignatchenko V, Sinha A, Boutros PC, Kislinger T.

Genome Med. 2017 Jul 18;9(1):62. doi: 10.1186/s13073-017-0454-9.

11.

Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors.

Jensen SR, Schoof EM, Wheeler SE, Hvid H, Ahnfelt-Rønne J, Hansen BF, Nishimura E, Olsen GS, Kislinger T, Brubaker PL.

Endocrinology. 2017 Aug 1;158(8):2470-2485. doi: 10.1210/en.2017-00194.

PMID:
28591806
12.

HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway.

Yamashita Y, Anczurowski M, Nakatsugawa M, Tanaka M, Kagoya Y, Sinha A, Chamoto K, Ochi T, Guo T, Saso K, Butler MO, Minden MD, Kislinger T, Hirano N.

Nat Commun. 2017 May 10;8:15244. doi: 10.1038/ncomms15244.

13.

Characterization of Protein Content Present in Exosomes Isolated from Conditioned Media and Urine.

Sinha A, Alfaro J, Kislinger T.

Curr Protoc Protein Sci. 2017 Feb 2;87:24.9.1-24.9.12. doi: 10.1002/cpps.23.

PMID:
28150884
14.

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.

Wang D, Pham NA, Tong J, Sakashita S, Allo G, Kim L, Yanagawa N, Raghavan V, Wei Y, To C, Trinh QM, Starmans MH, Chan-Seng-Yue MA, Chadwick D, Li L, Zhu CQ, Liu N, Li M, Lee S, Ignatchenko V, Strumpf D, Taylor P, Moghal N, Liu G, Boutros PC, Kislinger T, Pintilie M, Jurisica I, Shepherd FA, McPherson JD, Muthuswamy L, Moran MF, Tsao MS.

Int J Cancer. 2017 Feb 1;140(3):662-673. doi: 10.1002/ijc.30472. Epub 2016 Nov 7.

15.

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors.

Wojtowicz EE, Lechman ER, Hermans KG, Schoof EM, Wienholds E, Isserlin R, van Veelen PA, Broekhuis MJ, Janssen GM, Trotman-Grant A, Dobson SM, Krivdova G, Elzinga J, Kennedy J, Gan OI, Sinha A, Ignatchenko V, Kislinger T, Dethmers-Ausema B, Weersing E, Alemdehy MF, de Looper HW, Bader GD, Ritsema M, Erkeland SJ, Bystrykh LV, Dick JE, de Haan G.

Cell Stem Cell. 2016 Sep 1;19(3):383-96. doi: 10.1016/j.stem.2016.06.008. Epub 2016 Jul 14.

16.

Targeted proteomics identifies liquid-biopsy signatures for extracapsular prostate cancer.

Kim Y, Jeon J, Mejia S, Yao CQ, Ignatchenko V, Nyalwidhe JO, Gramolini AO, Lance RS, Troyer DA, Drake RR, Boutros PC, Semmes OJ, Kislinger T.

Nat Commun. 2016 Jun 28;7:11906. doi: 10.1038/ncomms11906.

17.

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia.

Banh RS, Iorio C, Marcotte R, Xu Y, Cojocari D, Rahman AA, Pawling J, Zhang W, Sinha A, Rose CM, Isasa M, Zhang S, Wu R, Virtanen C, Hitomi T, Habu T, Sidhu SS, Koizumi A, Wilkins SE, Kislinger T, Gygi SP, Schofield CJ, Dennis JW, Wouters BG, Neel BG.

Nat Cell Biol. 2016 Jul;18(7):803-813. doi: 10.1038/ncb3376. Epub 2016 Jun 20.

18.

Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland.

Baker L, BeGora M, Au Yeung F, Feigin ME, Rosenberg AZ, Lowe SW, Kislinger T, Muthuswamy SK.

J Cell Sci. 2016 Jun 15;129(12):2307-15. doi: 10.1242/jcs.185413. Epub 2016 May 13.

19.

Proteotranscriptomic Analysis Reveals Stage Specific Changes in the Molecular Landscape of Clear-Cell Renal Cell Carcinoma.

Neely BA, Wilkins CE, Marlow LA, Malyarenko D, Kim Y, Ignatchenko A, Sasinowska H, Sasinowski M, Nyalwidhe JO, Kislinger T, Copland JA, Drake RR.

PLoS One. 2016 Apr 29;11(4):e0154074. doi: 10.1371/journal.pone.0154074. eCollection 2016.

20.

Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery.

Nawaz M, Fatima F, Nazarenko I, Ekström K, Murtaza I, Anees M, Sultan A, Neder L, Camussi G, Valadi H, Squire JA, Kislinger T.

Expert Rev Proteomics. 2016;13(4):395-409. doi: 10.1586/14789450.2016.1165613. Review.

PMID:
26973172
21.

Proteogenomics: Opportunities and Caveats.

Dimitrakopoulos L, Prassas I, Diamandis EP, Nesvizhskii A, Kislinger T, Jaffe J, Drabovich A.

Clin Chem. 2016 Apr;62(4):551-7. doi: 10.1373/clinchem.2015.247858. Epub 2016 Jan 27. No abstract available.

22.

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.

Sharma P, Abbasi C, Lazic S, Teng AC, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO.

Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391.

PMID:
26403541
23.

A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan.

Ghavidel A, Baxi K, Ignatchenko V, Prusinkiewicz M, Arnason TG, Kislinger T, Carvalho CE, Harkness TA.

PLoS Genet. 2015 Aug 6;11(8):e1005429. doi: 10.1371/journal.pgen.1005429. eCollection 2015 Aug.

24.

Semi-supervised Learning Predicts Approximately One Third of the Alternative Splicing Isoforms as Functional Proteins.

Hao Y, Colak R, Teyra J, Corbi-Verge C, Ignatchenko A, Hahne H, Wilhelm M, Kuster B, Braun P, Kaida D, Kislinger T, Kim PM.

Cell Rep. 2015 Jul 14;12(2):183-9. doi: 10.1016/j.celrep.2015.06.031. Epub 2015 Jul 2.

25.

Using proteomics to probe neurons.

Kim Y, Kislinger T.

Elife. 2015 Jul 2;4:e09103. doi: 10.7554/eLife.09103.

26.

CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration.

Wei Y, Vellanki RN, Coyaud É, Ignatchenko V, Li L, Krieger JR, Taylor P, Tong J, Pham NA, Liu G, Raught B, Wouters BG, Kislinger T, Tsao MS, Moran MF.

Mol Cancer Res. 2015 Jul;13(7):1119-29. doi: 10.1158/1541-7786.MCR-14-0165-T. Epub 2015 Mar 17.

27.

Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice.

Jackson HW, Waterhouse P, Sinha A, Kislinger T, Berman HK, Khokha R.

Nat Cell Biol. 2015 Mar;17(3):217-27. doi: 10.1038/ncb3118. Epub 2015 Feb 23.

PMID:
25706237
28.

Novel insights into head and neck cancer using next-generation "omic" technologies.

Sepiashvili L, Bruce JP, Huang SH, O'Sullivan B, Liu FF, Kislinger T.

Cancer Res. 2015 Feb 1;75(3):480-6. doi: 10.1158/0008-5472.CAN-14-3124. Epub 2015 Jan 14. Review.

29.

VennDIS: a JavaFX-based Venn and Euler diagram software to generate publication quality figures.

Ignatchenko V, Ignatchenko A, Sinha A, Boutros PC, Kislinger T.

Proteomics. 2015 Apr;15(7):1239-44. doi: 10.1002/pmic.201400320. Epub 2015 Jan 23.

PMID:
25545689
30.

Integrated omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact.

Li L, Wei Y, To C, Zhu CQ, Tong J, Pham NA, Taylor P, Ignatchenko V, Ignatchenko A, Zhang W, Wang D, Yanagawa N, Li M, Pintilie M, Liu G, Muthuswamy L, Shepherd FA, Tsao MS, Kislinger T, Moran MF.

Nat Commun. 2014 Nov 28;5:5469. doi: 10.1038/ncomms6469.

PMID:
25429762
31.

The emerging role of extracellular vesicles as biomarkers for urogenital cancers.

Nawaz M, Camussi G, Valadi H, Nazarenko I, Ekström K, Wang X, Principe S, Shah N, Ashraf NM, Fatima F, Neder L, Kislinger T.

Nat Rev Urol. 2014 Dec;11(12):688-701. doi: 10.1038/nrurol.2014.301. Epub 2014 Nov 18. Review.

PMID:
25403245
32.

EVpedia: a community web portal for extracellular vesicles research.

Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Aikawa E, Baj-Krzyworzeka M, van Balkom BW, Belting M, Blanc L, Bond V, Bongiovanni A, Borràs FE, Buée L, Buzás EI, Cheng L, Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekström K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM, Nolte-'t Hoen E, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jørgensen M, Kim KP, Kim YK, Kislinger T, Lässer C, Lee DS, Lee H, van Leeuwen J, Lener T, Liu ML, Lötvall J, Marcilla A, Mathivanan S, Möller A, Morhayim J, Mullier F, Nazarenko I, Nieuwland R, Nunes DN, Pang K, Park J, Patel T, Pocsfalvi G, Del Portillo H, Putz U, Ramirez MI, Rodrigues ML, Roh TY, Royo F, Sahoo S, Schiffelers R, Sharma S, Siljander P, Simpson RJ, Soekmadji C, Stahl P, Stensballe A, Stępień E, Tahara H, Trummer A, Valadi H, Vella LJ, Wai SN, Witwer K, Yáñez-Mó M, Youn H, Zeidler R, Gho YS.

Bioinformatics. 2015 Mar 15;31(6):933-9. doi: 10.1093/bioinformatics/btu741. Epub 2014 Nov 10.

33.

Onco-proteogenomics: cancer proteomics joins forces with genomics.

Alfaro JA, Sinha A, Kislinger T, Boutros PC.

Nat Methods. 2014 Nov;11(11):1107-13. doi: 10.1038/nmeth.3138.

PMID:
25357240
34.

Proteomic analysis of human fetal atria and ventricle.

Lu ZQ, Sinha A, Sharma P, Kislinger T, Gramolini AO.

J Proteome Res. 2014 Dec 5;13(12):5869-78. doi: 10.1021/pr5007685. Epub 2014 Oct 31.

PMID:
25323733
35.

Integrated omic analysis of oropharyngeal carcinomas reveals human papillomavirus (HPV)-dependent regulation of the activator protein 1 (AP-1) pathway.

Sepiashvili L, Waggott D, Hui A, Shi W, Su S, Ignatchenko A, Ignatchenko V, Laureano M, Huang SH, Xu W, Weinreb I, Waldron J, O'Sullivan B, Irish JC, Boutros PC, Liu FF, Kislinger T.

Mol Cell Proteomics. 2014 Dec;13(12):3572-84. doi: 10.1074/mcp.M114.041764. Epub 2014 Sep 30.

36.

Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

Weinreb I, Piscuoglio S, Martelotto LG, Waggott D, Ng CK, Perez-Ordonez B, Harding NJ, Alfaro J, Chu KC, Viale A, Fusco N, da Cruz Paula A, Marchio C, Sakr RA, Lim R, Thompson LD, Chiosea SI, Seethala RR, Skalova A, Stelow EB, Fonseca I, Assaad A, How C, Wang J, de Borja R, Chan-Seng-Yue M, Howlett CJ, Nichols AC, Wen YH, Katabi N, Buchner N, Mullen L, Kislinger T, Wouters BG, Liu FF, Norton L, McPherson JD, Rubin BP, Clarke BA, Weigelt B, Boutros PC, Reis-Filho JS.

Nat Genet. 2014 Nov;46(11):1166-9. doi: 10.1038/ng.3096. Epub 2014 Sep 21.

37.

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state.

Shimoda M, Principe S, Jackson HW, Luga V, Fang H, Molyneux SD, Shao YW, Aiken A, Waterhouse PD, Karamboulas C, Hess FM, Ohtsuka T, Okada Y, Ailles L, Ludwig A, Wrana JL, Kislinger T, Khokha R.

Nat Cell Biol. 2014 Sep;16(9):889-901. doi: 10.1038/ncb3021. Epub 2014 Aug 24.

PMID:
25150980
38.

Global proteome analysis identifies active immunoproteasome subunits in human platelets.

Klockenbusch C, Walsh GM, Brown LM, Hoffman MD, Ignatchenko V, Kislinger T, Kast J.

Mol Cell Proteomics. 2014 Dec;13(12):3308-19. doi: 10.1074/mcp.M113.031757. Epub 2014 Aug 21.

39.

Serum proteomic analysis of a pre-symptomatic multiple sclerosis cohort.

Wallin MT, Oh U, Nyalwidhe J, Semmes J, Kislinger T, Coffman P, Kurtzke JF, Jacobson S.

Eur J Neurol. 2015 Mar;22(3):591-9. doi: 10.1111/ene.12534. Epub 2014 Aug 7.

PMID:
25104396
40.

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function.

Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, Strahl BD, Bouhassira EE, Edelmann W, Keogh MC.

Cell Rep. 2014 Mar 13;6(5):892-905. doi: 10.1016/j.celrep.2014.01.029. Epub 2014 Feb 22.

41.

The proteomics of prostate cancer exosomes.

Drake RR, Kislinger T.

Expert Rev Proteomics. 2014 Apr;11(2):167-77. doi: 10.1586/14789450.2014.890894. Epub 2014 Feb 25.

PMID:
24564711
42.

Proteomic profiles of human lung adeno and squamous cell carcinoma using super-SILAC and label-free quantification approaches.

Zhang W, Wei Y, Ignatchenko V, Li L, Sakashita S, Pham NA, Taylor P, Tsao MS, Kislinger T, Moran MF.

Proteomics. 2014 Mar;14(6):795-803. doi: 10.1002/pmic.201300382.

PMID:
24453208
43.

In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.

Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T.

Biochem Biophys Res Commun. 2014 Mar 21;445(4):694-701. doi: 10.1016/j.bbrc.2013.12.070. Epub 2014 Jan 14.

PMID:
24434149
44.

Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.

Garnier D, Magnus N, Meehan B, Kislinger T, Rak J.

Exp Cell Res. 2013 Oct 15;319(17):2747-57. doi: 10.1016/j.yexcr.2013.08.003. Epub 2013 Aug 13.

PMID:
23954818
45.

Novel approaches for the identification of biomarkers of aggressive prostate cancer.

Kim Y, Kislinger T.

Genome Med. 2013 Jun 28;5(6):56. doi: 10.1186/gm460. eCollection 2013. Review.

46.

Analysis of extracellular vesicles: new avenues for signaling biology and biomarker discovery.

Kislinger T.

Proteomics. 2013 May;13(10-11):1551-3. doi: 10.1002/pmic.201370095. No abstract available.

PMID:
23729288
47.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR.

Proteomics. 2013 May;13(10-11):1667-1671. doi: 10.1002/pmic.201200561. Epub 2013 Apr 23.

48.

Tumor-derived exosomes and microvesicles in head and neck cancer: implications for tumor biology and biomarker discovery.

Principe S, Hui AB, Bruce J, Sinha A, Liu FF, Kislinger T.

Proteomics. 2013 May;13(10-11):1608-23. doi: 10.1002/pmic.201200533. Review.

PMID:
23505015
49.

The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover.

Bohgaki M, Hakem A, Halaby MJ, Bohgaki T, Li Q, Bissey PA, Shloush J, Kislinger T, Sanchez O, Sheng Y, Hakem R.

Cell Death Differ. 2013 Jun;20(6):812-22. doi: 10.1038/cdd.2013.7. Epub 2013 Mar 1.

50.

A combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activation.

Draker R, Ng MK, Sarcinella E, Ignatchenko V, Kislinger T, Cheung P.

PLoS Genet. 2012;8(11):e1003047. doi: 10.1371/journal.pgen.1003047. Epub 2012 Nov 8.

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