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Items: 1 to 50 of 68

1.

Transient antibiotic resistance calls for attention.

Lázár V, Kishony R.

Nat Microbiol. 2019 Oct;4(10):1606-1607. doi: 10.1038/s41564-019-0571-x. No abstract available.

PMID:
31541208
2.

Personal clinical history predicts antibiotic resistance of urinary tract infections.

Yelin I, Snitser O, Novich G, Katz R, Tal O, Parizade M, Chodick G, Koren G, Shalev V, Kishony R.

Nat Med. 2019 Jul;25(7):1143-1152. doi: 10.1038/s41591-019-0503-6. Epub 2019 Jul 4.

PMID:
31273328
3.

Evolthon: A community endeavor to evolve lab evolution.

Kaminski Strauss S, Schirman D, Jona G, Brooks AN, Kunjapur AM, Nguyen Ba AN, Flint A, Solt A, Mershin A, Dixit A, Yona AH, Csörgő B, Busby BP, Hennig BP, Pál C, Schraivogel D, Schultz D, Wernick DG, Agashe D, Levi D, Zabezhinsky D, Russ D, Sass E, Tamar E, Herz E, Levy ED, Church GM, Yelin I, Nachman I, Gerst JE, Georgeson JM, Adamala KP, Steinmetz LM, Rübsam M, Ralser M, Klutstein M, Desai MM, Walunjkar N, Yin N, Aharon Hefetz N, Jakimo N, Snitser O, Adini O, Kumar P, Soo Hoo Smith R, Zeidan R, Hazan R, Rak R, Kishony R, Johnson S, Nouriel S, Vonesch SC, Foster S, Dagan T, Wein T, Karydis T, Wannier TM, Stiles T, Olin-Sandoval V, Mueller WF, Bar-On YM, Dahan O, Pilpel Y.

PLoS Biol. 2019 Mar 29;17(3):e3000182. doi: 10.1371/journal.pbio.3000182. eCollection 2019 Mar.

4.

A spotlight on bacterial mutations for 75 years.

Datta MS, Kishony R.

Nature. 2018 Nov;563(7733):633-644. doi: 10.1038/d41586-018-07521-8. No abstract available.

PMID:
30478371
5.

Additivity of inhibitory effects in multidrug combinations.

Russ D, Kishony R.

Nat Microbiol. 2018 Dec;3(12):1339-1345. doi: 10.1038/s41564-018-0252-1. Epub 2018 Oct 15.

6.

Nonoptimal Gene Expression Creates Latent Potential for Antibiotic Resistance.

Palmer AC, Chait R, Kishony R.

Mol Biol Evol. 2018 Nov 1;35(11):2669-2684. doi: 10.1093/molbev/msy163.

7.

Size Laws and Division Ring Dynamics in Filamentous Escherichia coli cells.

Wehrens M, Ershov D, Rozendaal R, Walker N, Schultz D, Kishony R, Levin PA, Tans SJ.

Curr Biol. 2018 Mar 19;28(6):972-979.e5. doi: 10.1016/j.cub.2018.02.006. Epub 2018 Mar 1.

8.

Antibiotic Resistance.

Yelin I, Kishony R.

Cell. 2018 Feb 22;172(5):1136-1136.e1. doi: 10.1016/j.cell.2018.02.018.

9.

Regulatory Dynamics Determine Cell Fate following Abrupt Antibiotic Exposure.

Schultz D, Palmer AC, Kishony R.

Cell Syst. 2017 Nov 22;5(5):509-517.e3. doi: 10.1016/j.cels.2017.10.002. Epub 2017 Nov 1.

10.

Global and local selection acting on the pathogen Stenotrophomonas maltophilia in the human lung.

Chung H, Lieberman TD, Vargas SO, Flett KB, McAdam AJ, Priebe GP, Kishony R.

Nat Commun. 2017 Jan 19;8:14078. doi: 10.1038/ncomms14078.

11.

RNA Structural Determinants of Optimal Codons Revealed by MAGE-Seq.

Kelsic ED, Chung H, Cohen N, Park J, Wang HH, Kishony R.

Cell Syst. 2016 Dec 21;3(6):563-571.e6. doi: 10.1016/j.cels.2016.11.004.

12.

Genomic diversity in autopsy samples reveals within-host dissemination of HIV-associated Mycobacterium tuberculosis.

Lieberman TD, Wilson D, Misra R, Xiong LL, Moodley P, Cohen T, Kishony R.

Nat Med. 2016 Dec;22(12):1470-1474. doi: 10.1038/nm.4205. Epub 2016 Oct 31.

13.

Compounds that select against the tetracycline-resistance efflux pump.

Stone LK, Baym M, Lieberman TD, Chait R, Clardy J, Kishony R.

Nat Chem Biol. 2016 Nov;12(11):902-904. doi: 10.1038/nchembio.2176. Epub 2016 Sep 19.

14.

A competitive trade-off limits the selective advantage of increased antibiotic production.

Gerardin Y, Springer M, Kishony R.

Nat Microbiol. 2016 Sep 26;1:16175. doi: 10.1038/nmicrobiol.2016.175.

15.

Spatiotemporal microbial evolution on antibiotic landscapes.

Baym M, Lieberman TD, Kelsic ED, Chait R, Gross R, Yelin I, Kishony R.

Science. 2016 Sep 9;353(6304):1147-51. doi: 10.1126/science.aag0822.

16.

High-order species interactions shape ecosystem diversity.

Bairey E, Kelsic ED, Kishony R.

Nat Commun. 2016 Aug 2;7:12285. doi: 10.1038/ncomms12285.

17.

Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments.

Chait R, Palmer AC, Yelin I, Kishony R.

Nat Commun. 2016 Jan 20;7:10333. doi: 10.1038/ncomms10333.

18.

Multidrug evolutionary strategies to reverse antibiotic resistance.

Baym M, Stone LK, Kishony R.

Science. 2016 Jan 1;351(6268):aad3292. doi: 10.1126/science.aad3292. Review.

19.

A Hybrid Drug Limits Resistance by Evading the Action of the Multiple Antibiotic Resistance Pathway.

Wang KK, Stone LK, Lieberman TD, Shavit M, Baasov T, Kishony R.

Mol Biol Evol. 2016 Feb;33(2):492-500. doi: 10.1093/molbev/msv243. Epub 2015 Nov 3.

20.

Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes.

Palmer AC, Toprak E, Baym M, Kim S, Veres A, Bershtein S, Kishony R.

Nat Commun. 2015 Jun 10;6:7385. doi: 10.1038/ncomms8385.

21.

Inexpensive multiplexed library preparation for megabase-sized genomes.

Baym M, Kryazhimskiy S, Lieberman TD, Chung H, Desai MM, Kishony R.

PLoS One. 2015 May 22;10(5):e0128036. doi: 10.1371/journal.pone.0128036. eCollection 2015. Erratum in: PLoS One. 2015;10(6):e0131262.

22.

Counteraction of antibiotic production and degradation stabilizes microbial communities.

Kelsic ED, Zhao J, Vetsigian K, Kishony R.

Nature. 2015 May 28;521(7553):516-9.

23.

Polyploidy can drive rapid adaptation in yeast.

Selmecki AM, Maruvka YE, Richmond PA, Guillet M, Shoresh N, Sorenson AL, De S, Kishony R, Michor F, Dowell R, Pellman D.

Nature. 2015 Mar 19;519(7543):349-52. doi: 10.1038/nature14187. Epub 2015 Mar 2.

24.

Editorial overview: Antimicrobials: grappling with the complexities of antibiotics and resistance.

Kishony R, Collins JJ.

Curr Opin Microbiol. 2014 Oct;21:v-vi. doi: 10.1016/j.mib.2014.10.004. Epub 2014 Oct 28. No abstract available.

PMID:
25444122
25.

Alternating antibiotic treatments constrain evolutionary paths to multidrug resistance.

Kim S, Lieberman TD, Kishony R.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14494-9. doi: 10.1073/pnas.1409800111. Epub 2014 Sep 22.

26.

Opposing effects of target overexpression reveal drug mechanisms.

Palmer AC, Kishony R.

Nat Commun. 2014 Jul 1;5:4296. doi: 10.1038/ncomms5296.

27.

Optimization and control in bacterial lag phase.

Schultz D, Kishony R.

BMC Biol. 2013 Dec 16;11:120. doi: 10.1186/1741-7007-11-120.

28.

Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures.

Lieberman TD, Flett KB, Yelin I, Martin TR, McAdam AJ, Priebe GP, Kishony R.

Nat Genet. 2014 Jan;46(1):82-7. doi: 10.1038/ng.2848. Epub 2013 Dec 8.

29.

Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition.

Toprak E, Veres A, Yildiz S, Pedraza JM, Chait R, Paulsson J, Kishony R.

Nat Protoc. 2013 Mar;8(3):555-67. doi: 10.1038/nprot.nprot.2013.021. Epub 2013 Feb 21.

30.

Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance.

Palmer AC, Kishony R.

Nat Rev Genet. 2013 Apr;14(4):243-8. doi: 10.1038/nrg3351. Epub 2013 Feb 19. Review.

31.

Distinct single-cell morphological dynamics under beta-lactam antibiotics.

Yao Z, Kahne D, Kishony R.

Mol Cell. 2012 Dec 14;48(5):705-12. doi: 10.1016/j.molcel.2012.09.016. Epub 2012 Oct 25.

32.

Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli.

Yao Z, Davis RM, Kishony R, Kahne D, Ruiz N.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):E2561-8. Epub 2012 Aug 20.

33.

Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection.

Skurnik D, Davis MR Jr, Benedetti D, Moravec KL, Cywes-Bentley C, Roux D, Traficante DC, Walsh RL, Maira-Litràn T, Cassidy SK, Hermos CR, Martin TR, Thakkallapalli EL, Vargas SO, McAdam AJ, Lieberman TD, Kishony R, Lipuma JJ, Pier GB, Goldberg JB, Priebe GP.

J Infect Dis. 2012 Jun;205(11):1709-18. doi: 10.1093/infdis/jis254. Epub 2012 Mar 23.

34.

Distinct growth strategies of soil bacteria as revealed by large-scale colony tracking.

Ernebjerg M, Kishony R.

Appl Environ Microbiol. 2012 Mar;78(5):1345-52. doi: 10.1128/AEM.06585-11. Epub 2011 Dec 22.

35.

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection.

Toprak E, Veres A, Michel JB, Chait R, Hartl DL, Kishony R.

Nat Genet. 2011 Dec 18;44(1):101-5. doi: 10.1038/ng.1034.

36.

What counters antibiotic resistance in nature?

Chait R, Vetsigian K, Kishony R.

Nat Chem Biol. 2011 Dec 15;8(1):2-5. doi: 10.1038/nchembio.745. No abstract available.

PMID:
22173342
37.

Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes.

Lieberman TD, Michel JB, Aingaran M, Potter-Bynoe G, Roux D, Davis MR Jr, Skurnik D, Leiby N, LiPuma JJ, Goldberg JB, McAdam AJ, Priebe GP, Kishony R.

Nat Genet. 2011 Nov 13;43(12):1275-80. doi: 10.1038/ng.997.

38.

Tackling antibiotic resistance.

Bush K, Courvalin P, Dantas G, Davies J, Eisenstein B, Huovinen P, Jacoby GA, Kishony R, Kreiswirth BN, Kutter E, Lerner SA, Levy S, Lewis K, Lomovskaya O, Miller JH, Mobashery S, Piddock LJ, Projan S, Thomas CM, Tomasz A, Tulkens PM, Walsh TR, Watson JD, Witkowski J, Witte W, Wright G, Yeh P, Zgurskaya HI.

Nat Rev Microbiol. 2011 Nov 2;9(12):894-6. doi: 10.1038/nrmicro2693. Review.

39.

Structure and evolution of Streptomyces interaction networks in soil and in silico.

Vetsigian K, Jajoo R, Kishony R.

PLoS Biol. 2011 Oct;9(10):e1001184. doi: 10.1371/journal.pbio.1001184. Epub 2011 Oct 25. Erratum in: PLoS Biol. 2011 Dec;9(12). doi:10.1371/annotation/1d584443-c6b8-423b-8027-5f9034d4599f.

40.

Systems biology.

Kishony R, Hatzimanikatis V.

Curr Opin Biotechnol. 2011 Aug;22(4):538-40. doi: 10.1016/j.copbio.2011.06.001. Epub 2011 Jul 15. No abstract available.

PMID:
21763123
41.

Resolution of gene regulatory conflicts caused by combinations of antibiotics.

Bollenbach T, Kishony R.

Mol Cell. 2011 May 20;42(4):413-25. doi: 10.1016/j.molcel.2011.04.016.

42.

Dynamic phenotypic clustering in noisy ecosystems.

Ernebjerg M, Kishony R.

PLoS Comput Biol. 2011 Mar;7(3):e1002017. doi: 10.1371/journal.pcbi.1002017. Epub 2011 Mar 17.

43.

A differential drug screen for compounds that select against antibiotic resistance.

Chait R, Shrestha S, Shah AK, Michel JB, Kishony R.

PLoS One. 2010 Dec 8;5(12):e15179. doi: 10.1371/journal.pone.0015179.

44.

Optimal drug synergy in antimicrobial treatments.

Torella JP, Chait R, Kishony R.

PLoS Comput Biol. 2010 Jun 3;6(6):e1000796. doi: 10.1371/journal.pcbi.1000796. Erratum in: PLoS Comput Biol. 2010;6(7). doi: 10.1371/annotation/2505c54a-329b-4553-ad82-cb4b38100ffa. PLoS Comput Biol. 2010;6(7). doi: 10.1371/annotation/4117feb8-90b6-474f-aba8-0da4aa4b7c21.

45.

Need-based up-regulation of protein levels in response to deletion of their duplicate genes.

DeLuna A, Springer M, Kirschner MW, Kishony R.

PLoS Biol. 2010 Mar 30;8(3):e1000347. doi: 10.1371/journal.pbio.1000347.

46.

Chemical decay of an antibiotic inverts selection for resistance.

Palmer AC, Angelino E, Kishony R.

Nat Chem Biol. 2010 Mar;6(3):244. No abstract available.

PMID:
20154670
47.

Chemical decay of an antibiotic inverts selection for resistance.

Palmer AC, Angelino E, Kishony R.

Nat Chem Biol. 2010 Feb;6(2):105-7. doi: 10.1038/nchembio.289. Epub 2010 Jan 10.

48.

Hydroxyurea triggers cellular responses that actively cause bacterial cell death.

Bollenbach T, Kishony R.

Mol Cell. 2009 Dec 11;36(5):728-9. doi: 10.1016/j.molcel.2009.11.027.

49.

Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery.

Chung HS, Yao Z, Goehring NW, Kishony R, Beckwith J, Kahne D.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21872-7. doi: 10.1073/pnas.0911674106. Epub 2009 Dec 7.

50.

Nonoptimal microbial response to antibiotics underlies suppressive drug interactions.

Bollenbach T, Quan S, Chait R, Kishony R.

Cell. 2009 Nov 13;139(4):707-18. doi: 10.1016/j.cell.2009.10.025.

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