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Items: 1 to 50 of 112

1.

Chemokine CXCL1 is responsible for cocaine-induced reward in mice.

Saika F, Matsuzaki S, Kobayashi D, Kiguchi N, Kishioka S.

Neuropsychopharmacol Rep. 2018 Sep;38(3):145-148. doi: 10.1002/npr2.12018. Epub 2018 Jun 29.

2.

A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates.

Ding H, Kiguchi N, Yasuda D, Daga PR, Polgar WE, Lu JJ, Czoty PW, Kishioka S, Zaveri NT, Ko MC.

Sci Transl Med. 2018 Aug 29;10(456). pii: eaar3483. doi: 10.1126/scitranslmed.aar3483.

PMID:
30158150
3.

Differential mRNA expression of neuroinflammatory modulators in the spinal cord and thalamus of type 2 diabetic monkeys.

Ding H, Kiguchi N, Kishioka S, Ma T, Peters CM, Ko MC.

J Diabetes. 2018 May 11. doi: 10.1111/1753-0407.12780. [Epub ahead of print]

PMID:
29749036
4.

Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury.

Kiguchi N, Kobayashi D, Saika F, Matsuzaki S, Kishioka S.

J Neuroinflammation. 2018 Mar 27;15(1):96. doi: 10.1186/s12974-018-1133-5.

5.

Upregulation of CCL7 and CCL2 in reward system mediated through dopamine D1 receptor signaling underlies methamphetamine-induced place preference in mice.

Saika F, Kiguchi N, Wakida N, Kobayashi D, Fukazawa Y, Matsuzaki S, Kishioka S.

Neurosci Lett. 2018 Feb 5;665:33-37. doi: 10.1016/j.neulet.2017.11.042. Epub 2017 Nov 22.

PMID:
29174638
6.

Pharmacological Regulation of Neuropathic Pain Driven by Inflammatory Macrophages.

Kiguchi N, Kobayashi D, Saika F, Matsuzaki S, Kishioka S.

Int J Mol Sci. 2017 Nov 1;18(11). pii: E2296. doi: 10.3390/ijms18112296. Review.

7.

Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation.

Kiguchi N, Sakaguchi H, Kadowaki Y, Saika F, Fukazawa Y, Matsuzaki S, Kishioka S.

J Pharmacol Sci. 2017 Jan;133(1):53-56. doi: 10.1016/j.jphs.2016.11.005. Epub 2016 Dec 23.

8.

Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys.

Kiguchi N, Ding H, Peters CM, Kock ND, Kishioka S, Cline JM, Wagner JD, Ko MC.

Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):274-283. doi: 10.1016/j.bbadis.2016.10.007. Epub 2016 Oct 14.

9.

[The role of CC-chemokine ligand 2 in the development of psychic dependence on methamphetamine].

Saika F, Kiguchi N, Kishioka S.

Nihon Arukoru Yakubutsu Igakkai Zasshi. 2015 Oct;50(5):189-95. Review. Japanese.

PMID:
26946780
10.

Spinal Functions of B-Type Natriuretic Peptide, Gastrin-Releasing Peptide, and Their Cognate Receptors for Regulating Itch in Mice.

Kiguchi N, Sukhtankar DD, Ding H, Tanaka K, Kishioka S, Peters CM, Ko MC.

J Pharmacol Exp Ther. 2016 Mar;356(3):596-603. doi: 10.1124/jpet.115.229997. Epub 2015 Dec 15.

11.

[Exploration of novel therapeutic targets for neuropathic pain based on the regulation of immune cells].

Kobayashi Y, Kiguchi N, Saika F, Kishioka S.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2015 Jun;35(3):65-72. Review. Japanese.

PMID:
26281298
12.

TC-2559, an α4β2 nicotinic acetylcholine receptor agonist, suppresses the expression of CCL3 and IL-1β through STAT3 inhibition in cultured murine macrophages.

Kiguchi N, Saika F, Kobayashi Y, Ko MC, Kishioka S.

J Pharmacol Sci. 2015 Jun;128(2):83-6. doi: 10.1016/j.jphs.2015.04.009. Epub 2015 May 8.

13.

Macrophage-T cell interactions mediate neuropathic pain through the glucocorticoid-induced tumor necrosis factor ligand system.

Kobayashi Y, Kiguchi N, Fukazawa Y, Saika F, Maeda T, Kishioka S.

J Biol Chem. 2015 May 15;290(20):12603-13. doi: 10.1074/jbc.M115.636506. Epub 2015 Mar 18.

14.

[Development of physical dependence on nicotine and endogenous opioid system--participation of α7 nicotinic acetylcholine receptor].

Kishioka S, Kiguchi N, Kobayashi Y, Saika F, Yamamoto C.

Nihon Arukoru Yakubutsu Igakkai Zasshi. 2014 Oct;49(5):227-37. Review. Japanese.

PMID:
25651617
15.

Peripheral interleukin-4 ameliorates inflammatory macrophage-dependent neuropathic pain.

Kiguchi N, Kobayashi Y, Saika F, Sakaguchi H, Maeda T, Kishioka S.

Pain. 2015 Apr;156(4):684-93. doi: 10.1097/j.pain.0000000000000097.

PMID:
25630024
16.

Peripheral alpha4beta2 nicotinic acetylcholine receptor signalling attenuates tactile allodynia and thermal hyperalgesia after nerve injury in mice.

Saika F, Kiguchi N, Kobayashi Y, Kishioka S.

Acta Physiol (Oxf). 2015 Feb;213(2):462-71. doi: 10.1111/apha.12437. Epub 2014 Dec 29.

PMID:
25491757
17.

Epigenetic regulation of CC-chemokine ligand 2 in nonresolving inflammation.

Kiguchi N, Saika F, Kobayashi Y, Kishioka S.

Biomol Concepts. 2014 Aug;5(4):265-73. doi: 10.1515/bmc-2014-0022. Review.

PMID:
25372758
18.

Nicotine effects and the endogenous opioid system.

Kishioka S, Kiguchi N, Kobayashi Y, Saika F.

J Pharmacol Sci. 2014;125(2):117-24. Epub 2014 May 31. Review.

19.

CC-chemokine ligand 2 facilitates conditioned place preference to methamphetamine through the activation of dopamine systems.

Wakida N, Kiguchi N, Saika F, Nishiue H, Kobayashi Y, Kishioka S.

J Pharmacol Sci. 2014;125(1):68-73. Epub 2014 Apr 19.

21.

Possible involvement of endogenous opioid system located downstream of α7 nicotinic acetylcholine receptor in mice with physical dependence on nicotine.

Ueno K, Kiguchi N, Kobayashi Y, Saika F, Wakida N, Yamamoto C, Maeda T, Ozaki M, Kishioka S.

J Pharmacol Sci. 2014;124(1):47-53. Epub 2013 Dec 21.

22.

Vascular endothelial growth factor signaling in injured nerves underlies peripheral sensitization in neuropathic pain.

Kiguchi N, Kobayashi Y, Kadowaki Y, Fukazawa Y, Saika F, Kishioka S.

J Neurochem. 2014 Apr;129(1):169-78. doi: 10.1111/jnc.12614. Epub 2013 Dec 4.

23.

HMGB1 as a potential therapeutic target for neuropathic pain.

Maeda T, Ozaki M, Kobayashi Y, Kiguchi N, Kishioka S.

J Pharmacol Sci. 2013;123(4):301-5. Epub 2013 Nov 26. Review.

24.

Epigenetic upregulation of CCL2 and CCL3 via histone modifications in infiltrating macrophages after peripheral nerve injury.

Kiguchi N, Kobayashi Y, Saika F, Kishioka S.

Cytokine. 2013 Dec;64(3):666-72. doi: 10.1016/j.cyto.2013.09.019. Epub 2013 Oct 14.

PMID:
24135048
25.

Pharmacokinetic evidence for the long-lasting effect of nor-binaltorphimine, a potent kappa opioid receptor antagonist, in mice.

Kishioka S, Kiguchi N, Kobayashi Y, Yamamoto C, Saika F, Wakida N, Ko MC, Woods JH.

Neurosci Lett. 2013 Sep 27;552:98-102. doi: 10.1016/j.neulet.2013.07.040. Epub 2013 Aug 7.

PMID:
23933210
26.

Activation of nicotinic acetylcholine receptors on bone marrow-derived cells relieves neuropathic pain accompanied by peripheral neuroinflammation.

Kiguchi N, Kobayashi Y, Maeda T, Tominaga S, Nakamura J, Fukazawa Y, Ozaki M, Kishioka S.

Neurochem Int. 2012 Dec;61(7):1212-9. doi: 10.1016/j.neuint.2012.09.001. Epub 2012 Sep 16.

PMID:
22989685
27.

CC-chemokine ligand 4/macrophage inflammatory protein-1β participates in the induction of neuropathic pain after peripheral nerve injury.

Saika F, Kiguchi N, Kobayashi Y, Fukazawa Y, Kishioka S.

Eur J Pain. 2012 Oct;16(9):1271-80. doi: 10.1002/j.1532-2149.2012.00146.x. Epub 2012 Apr 24.

PMID:
22528550
28.

The critical role of spinal ceramide in the development of partial sciatic nerve ligation-induced neuropathic pain in mice.

Kobayashi Y, Kiguchi N, Maeda T, Ozaki M, Kishioka S.

Biochem Biophys Res Commun. 2012 May 4;421(2):318-22. doi: 10.1016/j.bbrc.2012.03.153. Epub 2012 Apr 7.

PMID:
22503971
29.

Availability of serum corticosterone level for quantitative evaluation of morphine withdrawal in mice.

Ueno K, Maeda T, Kiguchi N, Kobayashi Y, Ozaki M, Kishioka S.

Drug Discov Ther. 2011 Apr;5(2):71-5.

30.

Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms.

Iwai S, Kiguchi N, Kobayashi Y, Fukazawa Y, Saika F, Ueno K, Yamamoto C, Kishioka S.

Drug Discov Ther. 2012 Feb;6(1):31-7.

31.

Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein.

Fujita-Hamabe W, Nishida M, Nawa A, Kobori T, Nakamoto K, Kishioka S, Tokuyama S.

J Pharm Pharmacol. 2012 Apr;64(4):496-504. doi: 10.1111/j.2042-7158.2011.01426.x. Epub 2011 Dec 29.

PMID:
22420656
32.

Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain.

Kiguchi N, Kobayashi Y, Maeda T, Fukazawa Y, Tohya K, Kimura M, Kishioka S.

J Pharmacol Exp Ther. 2012 Mar;340(3):577-87. doi: 10.1124/jpet.111.187724. Epub 2011 Dec 1.

33.

Pharmacological relationship between nicotinic and opioid systems in analgesia and corticosterone elevation.

Yamamoto A, Kiguchi N, Kobayashi Y, Maeda T, Ueno K, Yamamoto C, Kishioka S.

Life Sci. 2011 Dec 19;89(25-26):956-61. doi: 10.1016/j.lfs.2011.10.004. Epub 2011 Oct 20.

PMID:
22036617
34.

Chemokines and cytokines in neuroinflammation leading to neuropathic pain.

Kiguchi N, Kobayashi Y, Kishioka S.

Curr Opin Pharmacol. 2012 Feb;12(1):55-61. doi: 10.1016/j.coph.2011.10.007. Epub 2011 Oct 21. Review.

PMID:
22019566
35.

Permanent relief from intermittent cold stress-induced fibromyalgia-like abnormal pain by repeated intrathecal administration of antidepressants.

Nishiyori M, Uchida H, Nagai J, Araki K, Mukae T, Kishioka S, Ueda H.

Mol Pain. 2011 Sep 21;7:69. doi: 10.1186/1744-8069-7-69.

36.

Decreased expression of intestinal P-glycoprotein increases the analgesic effects of oral morphine in a streptozotocin-induced diabetic mouse model.

Nawa A, Fujita-Hamabe W, Kishioka S, Tokuyama S.

Drug Metab Pharmacokinet. 2011;26(6):584-91. Epub 2011 Aug 30.

37.

CC-chemokine MIP-1α in the spinal cord contributes to nerve injury-induced neuropathic pain.

Kiguchi N, Kobayashi Y, Maeda T, Saika F, Kishioka S.

Neurosci Lett. 2010 Oct 22;484(1):17-21. doi: 10.1016/j.neulet.2010.07.085. Epub 2010 Aug 6.

PMID:
20692319
38.
39.

Macrophage inflammatory protein-1alpha mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1beta up-regulation.

Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S.

Pain. 2010 May;149(2):305-15. doi: 10.1016/j.pain.2010.02.025. Epub 2010 Mar 12.

PMID:
20223588
40.

Interactions between morphine and nitric oxide in various organs.

Toda N, Kishioka S, Hatano Y, Toda H.

J Anesth. 2009;23(4):554-68. doi: 10.1007/s00540-009-0793-9. Epub 2009 Nov 18. Review.

PMID:
19921366
41.

Activation of extracellular signal-regulated kinase in sciatic nerve contributes to neuropathic pain after partial sciatic nerve ligation in mice.

Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S.

Anesth Analg. 2009 Oct;109(4):1305-11. doi: 10.1213/ane.0b013e3181b1dca2.

PMID:
19762761
42.

Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation.

Maeda T, Kiguchi N, Kobayashi Y, Ikuta T, Ozaki M, Kishioka S.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13076-81. doi: 10.1073/pnas.0903524106. Epub 2009 Jul 20.

43.

Involvement of inflammatory mediators in neuropathic pain caused by vincristine.

Kiguchi N, Maeda T, Kobayashi Y, Saika F, Kishioka S.

Int Rev Neurobiol. 2009;85:179-90. doi: 10.1016/S0074-7742(09)85014-9. Review.

PMID:
19607970
44.

PPAR and Pain.

Maeda T, Kishioka S.

Int Rev Neurobiol. 2009;85:165-77. doi: 10.1016/S0074-7742(09)85013-7. Review.

PMID:
19607969
45.

Suppressive effect of imipramine on vincristine-induced mechanical allodynia in mice.

Saika F, Kiguchi N, Kobayashi Y, Fukazawa Y, Maeda T, Ozaki M, Kishioka S.

Biol Pharm Bull. 2009 Jul;32(7):1231-4.

46.

Identification of radicals formed in the reaction mixture of bovine kidney microsomes with NADPH.

Kumamoto K, Hirai T, Kishioka S, Iwahashi H.

J Biochem. 2009 Oct;146(4):571-9. doi: 10.1093/jb/mvp101. Epub 2009 Jun 29.

PMID:
19564158
47.

Leptin enhances CC-chemokine ligand expression in cultured murine macrophage.

Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S.

Biochem Biophys Res Commun. 2009 Jul 3;384(3):311-5. doi: 10.1016/j.bbrc.2009.04.121. Epub 2009 May 3.

PMID:
19409880
48.

Design, synthesis and SAR studies of tripeptide analogs with the scaffold 3-phenylpropane-1,2-diamine as aminopeptidase N/CD13 inhibitors.

Shang L, Fang H, Zhu H, Wang X, Wang Q, Mu J, Wang B, Kishioka S, Xu W.

Bioorg Med Chem. 2009 Apr 1;17(7):2775-84. doi: 10.1016/j.bmc.2009.02.034. Epub 2009 Feb 24.

PMID:
19299146
49.

The pharmacological mechanisms of electroacupuncture.

Fukazawa Y, Maeda T, Kishioka S.

Curr Opin Investig Drugs. 2009 Jan;10(1):62-9. Review.

PMID:
19127488
50.

Modulation of opioid actions by nitric oxide signaling.

Toda N, Kishioka S, Hatano Y, Toda H.

Anesthesiology. 2009 Jan;110(1):166-81. doi: 10.1097/ALN.0b013e31819146a9. Review.

PMID:
19104184

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