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Items: 43

1.

Expression patterns of signaling lymphocytic activation molecule family members in peripheral blood mononuclear cell subsets in patients with systemic lupus erythematosus.

Karampetsou MP, Comte D, Kis-Toth K, Kyttaris VC, Tsokos GC.

PLoS One. 2017 Oct 11;12(10):e0186073. doi: 10.1371/journal.pone.0186073. eCollection 2017.

2.

Signaling Lymphocytic Activation Molecule Family Member 7 Engagement Restores Defective Effector CD8+ T Cell Function in Systemic Lupus Erythematosus.

Comte D, Karampetsou MP, Yoshida N, Kis-Toth K, Kyttaris VC, Tsokos GC.

Arthritis Rheumatol. 2017 May;69(5):1035-1044. doi: 10.1002/art.40038.

3.

Brief Report: CD4+ T Cells From Patients With Systemic Lupus Erythematosus Respond Poorly to Exogenous Interleukin-2.

Comte D, Karampetsou MP, Kis-Toth K, Yoshida N, Bradley SJ, Kyttaris VC, Tsokos GC.

Arthritis Rheumatol. 2017 Apr;69(4):808-813. doi: 10.1002/art.40014.

4.

Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus.

Comte D, Karampetsou MP, Kis-Toth K, Yoshida N, Bradley SJ, Mizui M, Kono M, Solomon JR, Kyttaris VC, Tsokos GC.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9321-6. doi: 10.1073/pnas.1605081113. Epub 2016 Aug 1.

5.

Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production.

Karampetsou MP, Comte D, Kis-Toth K, Terhorst C, Kyttaris VC, Tsokos GC.

J Immunol. 2016 Jun 15;196(12):4915-24. doi: 10.4049/jimmunol.1501523. Epub 2016 May 11.

6.

Selective Loss of Signaling Lymphocytic Activation Molecule Family Member 4-Positive CD8+ T Cells Contributes to the Decreased Cytotoxic Cell Activity in Systemic Lupus Erythematosus.

Kis-Toth K, Comte D, Karampetsou MP, Kyttaris VC, Kannan L, Terhorst C, Tsokos GC.

Arthritis Rheumatol. 2016 Jan;68(1):164-73. doi: 10.1002/art.39410.

7.

Mesenchymal Stromal Cell-Like Cells Set the Balance of Stimulatory and Inhibitory Signals in Monocyte-Derived Dendritic Cells.

Bacskai I, Mázló A, Kis-Tóth K, Szabó A, Panyi G, Sarkadi B, Apáti Á, Rajnavölgyi É.

Stem Cells Dev. 2015 Aug 1;24(15):1805-16. doi: 10.1089/scd.2014.0509. Epub 2015 Apr 29.

PMID:
25808140
8.

Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis.

Walter JE, Lo MS, Kis-Toth K, Tirosh I, Frugoni F, Lee YN, Csomos K, Chen K, Pillai S, Dunham J, Tsokos GC, Luning Prak ET, Notarangelo LD.

J Allergy Clin Immunol. 2015 Jan;135(1):272-3. doi: 10.1016/j.jaci.2014.07.063. Epub 2014 Oct 11. No abstract available.

9.

Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival.

Kis-Toth K, Tsokos GC.

J Immunol. 2014 May 1;192(9):4436-42. doi: 10.4049/jimmunol.1302909. Epub 2014 Mar 26.

10.

A T cell gene expression panel for the diagnosis and monitoring of disease activity in patients with systemic lupus erythematosus.

Grammatikos AP, Kyttaris VC, Kis-Toth K, Fitzgerald LM, Devlin A, Finnell MD, Tsokos GC.

Clin Immunol. 2014 Feb;150(2):192-200. doi: 10.1016/j.clim.2013.12.002. Epub 2013 Dec 16.

11.

Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Fas(lpr) mouse.

Thai TH, Patterson HC, Pham DH, Kis-Toth K, Kaminski DA, Tsokos GC.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20194-9. doi: 10.1073/pnas.1317632110. Epub 2013 Nov 26.

12.

R-spondin3 prevents mesenteric ischemia/reperfusion-induced tissue damage by tightening endothelium and preventing vascular leakage.

Kannan L, Kis-Toth K, Yoshiya K, Thai TH, Sehrawat S, Mayadas TN, Dalle Lucca JJ, Tsokos GC.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14348-53. doi: 10.1073/pnas.1309393110. Epub 2013 Aug 13.

13.

Monocyte-derived dendritic cell subpopulations use different types of matrix metalloproteinases inhibited by GM6001.

Kis-Toth K, Bacskai I, Gogolak P, Mazlo A, Szatmari I, Rajnavolgyi E.

Immunobiology. 2013 Nov;218(11):1361-9. doi: 10.1016/j.imbio.2013.06.012. Epub 2013 Jul 2.

PMID:
23870824
14.

Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor.

Keszei M, Detre C, Castro W, Magelky E, O'Keeffe M, Kis-Toth K, Tsokos GC, Wang N, Terhorst C.

FASEB J. 2013 Aug;27(8):3123-31. doi: 10.1096/fj.12-226951. Epub 2013 Apr 29.

15.

Glucocorticoids suppress T cell function by up-regulating microRNA-98.

Davis TE, Kis-Toth K, Szanto A, Tsokos GC.

Arthritis Rheum. 2013 Jul;65(7):1882-90. doi: 10.1002/art.37966.

16.

The two-component adjuvant IC31® boosts type i interferon production of human monocyte-derived dendritic cells via ligation of endosomal TLRs.

Szabo A, Gogolak P, Pazmandi K, Kis-Toth K, Riedl K, Wizel B, Lingnau K, Bacsi A, Rethi B, Rajnavolgyi E.

PLoS One. 2013;8(2):e55264. doi: 10.1371/journal.pone.0055264. Epub 2013 Feb 6. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/322893f7-942c-4059-9295-7ecd26162aca.

17.

Brief report: increased expression of a short splice variant of CTLA-4 exacerbates lupus in MRL/lpr mice.

Ichinose K, Zhang Z, Koga T, Juang YT, Kis-Tóth K, Sharpe AH, Kuchroo V, Crispín JC, Tsokos GC.

Arthritis Rheum. 2013 Mar;65(3):764-9. doi: 10.1002/art.37790.

18.

SAP expression in invariant NKT cells is required for cognate help to support B-cell responses.

Detre C, Keszei M, Garrido-Mesa N, Kis-Toth K, Castro W, Agyemang AF, Veerapen N, Besra GS, Carroll MC, Tsokos GC, Wang N, Leadbetter EA, Terhorst C.

Blood. 2012 Jul 5;120(1):122-9. doi: 10.1182/blood-2011-11-395913. Epub 2012 May 21.

19.

Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID mice.

Kis-Toth K, Radacs M, Olasz K, van Eden W, Mikecz K, Glant TT.

Int Immunol. 2012 Aug;24(8):507-17. doi: 10.1093/intimm/dxs057. Epub 2012 Apr 19.

20.

A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells.

Rauen T, Juang YT, Hedrich CM, Kis-Toth K, Tsokos GC.

Genes Immun. 2012 Jun;13(4):346-50. doi: 10.1038/gene.2011.85. Epub 2012 Jan 12.

PMID:
22237416
21.

T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice.

Olasz K, Boldizsar F, Kis-Toth K, Tarjanyi O, Hegyi A, van Eden W, Rauch TA, Mikecz K, Glant TT.

Clin Exp Immunol. 2012 Feb;167(2):346-55. doi: 10.1111/j.1365-2249.2011.04506.x.

22.

Histamine modulates multiple functional activities of monocyte-derived dendritic cell subsets via histamine receptor 2.

Simon T, Gogolák P, Kis-Tóth K, Jelinek I, László V, Rajnavölgyi E.

Int Immunol. 2012 Feb;24(2):107-16. doi: 10.1093/intimm/dxr107. Epub 2012 Jan 9.

PMID:
22232416
23.

Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation.

Chatterjee M, Rauen T, Kis-Toth K, Kyttaris VC, Hedrich CM, Terhorst C, Tsokos GC.

J Immunol. 2012 Feb 1;188(3):1206-12. doi: 10.4049/jimmunol.1102773. Epub 2011 Dec 19.

24.

cAMP-responsive element modulator α (CREMα) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE).

Hedrich CM, Rauen T, Kis-Toth K, Kyttaris VC, Tsokos GC.

J Biol Chem. 2012 Feb 10;287(7):4715-25. doi: 10.1074/jbc.M111.323261. Epub 2011 Dec 19.

25.

Cutting edge: Calcium/Calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis.

Ichinose K, Rauen T, Juang YT, Kis-Toth K, Mizui M, Koga T, Tsokos GC.

J Immunol. 2011 Dec 1;187(11):5500-4. doi: 10.4049/jimmunol.1102357. Epub 2011 Oct 26.

26.

CREMα suppresses spleen tyrosine kinase expression in normal but not systemic lupus erythematosus T cells.

Ghosh D, Kis-Toth K, Juang YT, Tsokos GC.

Arthritis Rheum. 2012 Mar;64(3):799-807. doi: 10.1002/art.33375.

27.

The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading.

Lányi Á, Baráth M, Péterfi Z, Bogel G, Orient A, Simon T, Petrovszki E, Kis-Tóth K, Sirokmány G, Rajnavölgyi É, Terhorst C, Buday L, Geiszt M.

PLoS One. 2011;6(8):e23653. doi: 10.1371/journal.pone.0023653. Epub 2011 Aug 23.

28.

The dysregulation of cytokine networks in systemic lupus erythematosus.

Apostolidis SA, Lieberman LA, Kis-Toth K, Crispín JC, Tsokos GC.

J Interferon Cytokine Res. 2011 Oct;31(10):769-79. doi: 10.1089/jir.2011.0029. Epub 2011 Aug 30. Review.

29.

Phospholipase Cγ2 is required for basal but not oestrogen deficiency-induced bone resorption.

Kertész Z, Gyori D, Körmendi S, Fekete T, Kis-Tóth K, Jakus Z, Schett G, Rajnavölgyi E, Dobó-Nagy C, Mócsai A.

Eur J Clin Invest. 2012 Jan;42(1):49-60. doi: 10.1111/j.1365-2362.2011.02556.x. Epub 2011 Jul 12.

30.

Voltage-gated sodium channel Nav1.7 maintains the membrane potential and regulates the activation and chemokine-induced migration of a monocyte-derived dendritic cell subset.

Kis-Toth K, Hajdu P, Bacskai I, Szilagyi O, Papp F, Szanto A, Posta E, Gogolak P, Panyi G, Rajnavolgyi E.

J Immunol. 2011 Aug 1;187(3):1273-80. doi: 10.4049/jimmunol.1003345. Epub 2011 Jun 29.

31.

Cytosolic DNA-activated human dendritic cells are potent activators of the adaptive immune response.

Kis-Toth K, Szanto A, Thai TH, Tsokos GC.

J Immunol. 2011 Aug 1;187(3):1222-34. doi: 10.4049/jimmunol.1100469. Epub 2011 Jun 27.

32.

Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans.

Nesterovitch AB, Szanto S, Gonda A, Bardos T, Kis-Toth K, Adarichev VA, Olasz K, Ghassemi-Najad S, Hoffman MD, Tharp MD, Mikecz K, Glant TT.

Am J Pathol. 2011 Apr;178(4):1701-14. doi: 10.1016/j.ajpath.2010.12.053.

33.

SLAMF6-driven co-stimulation of human peripheral T cells is defective in SLE T cells.

Chatterjee M, Kis-Toth K, Thai TH, Terhorst C, Tsokos GC.

Autoimmunity. 2011 May;44(3):211-8. doi: 10.3109/08916934.2010.530627. Epub 2011 Jan 14.

34.

A systemic lupus erythematosus gene expression array in disease diagnosis and classification: a preliminary report.

Juang YT, Peoples C, Kafri R, Kyttaris VC, Sunahori K, Kis-Toth K, Fitzgerald L, Ergin S, Finnell M, Tsokos GC.

Lupus. 2011 Mar;20(3):243-9. doi: 10.1177/0961203310383072. Epub 2010 Dec 7.

35.

Suppression of autoimmunity and organ pathology in lupus-prone mice upon inhibition of calcium/calmodulin-dependent protein kinase type IV.

Ichinose K, Juang YT, Crispín JC, Kis-Toth K, Tsokos GC.

Arthritis Rheum. 2011 Feb;63(2):523-9. doi: 10.1002/art.30085.

36.

Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice.

Boldizsar F, Kis-Toth K, Tarjanyi O, Olasz K, Hegyi A, Mikecz K, Glant TT.

Arthritis Rheum. 2010 Oct;62(10):2984-94. doi: 10.1002/art.27614.

37.

Pathogenesis of human systemic lupus erythematosus: recent advances.

Crispín JC, Liossis SN, Kis-Toth K, Lieberman LA, Kyttaris VC, Juang YT, Tsokos GC.

Trends Mol Med. 2010 Feb;16(2):47-57. doi: 10.1016/j.molmed.2009.12.005. Epub 2010 Feb 4. Review.

38.

Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation.

Kis-Toth K, Tsokos GC.

Autoimmunity. 2010 Mar;43(2):121-30. doi: 10.3109/08916930903214041. Review.

PMID:
20102311
39.

Developmental switch of the expression of ion channels in human dendritic cells.

Zsiros E, Kis-Toth K, Hajdu P, Gaspar R, Bielanska J, Felipe A, Rajnavolgyi E, Panyi G.

J Immunol. 2009 Oct 1;183(7):4483-92. doi: 10.4049/jimmunol.0803003. Epub 2009 Sep 11.

40.

Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast-mediated pathologic bone resorption.

Tunyogi-Csapo M, Kis-Toth K, Radacs M, Farkas B, Jacobs JJ, Finnegan A, Mikecz K, Glant TT.

Arthritis Rheum. 2008 Aug;58(8):2397-408. doi: 10.1002/art.23653.

41.

Congenic strains displaying similar clinical phenotype of arthritis represent different immunologic models of inflammation.

Adarichev VA, Vegvari A, Szabo Z, Kis-Toth K, Mikecz K, Glant TT.

Genes Immun. 2008 Oct;9(7):591-601. doi: 10.1038/gene.2008.54. Epub 2008 Jul 24.

42.

Two loci on chromosome 15 control experimentally induced arthritis through the differential regulation of IL-6 and lymphocyte proliferation.

Glant TT, Szántó S, Vegvari A, Szabo Z, Kis-Toth K, Mikecz K, Adarichev VA.

J Immunol. 2008 Jul 15;181(2):1307-14.

43.

Activation-induced apoptosis and cell surface expression of Fas (CD95) ligand are reciprocally regulated by retinoic acid receptor alpha and gamma and involve nur77 in T cells.

Tóth R, Szegezdi E, Reichert U, Bernardon JM, Michel S, Ancian P, Kis-Tóth K, Macsári Z, Fésüs L, Szondy Z.

Eur J Immunol. 2001 May;31(5):1382-91.

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