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The impact of switching to clozapine on psychiatric hospital admissions: a mirror-image study.

Kirwan P, O'Connor L, Sharma K, McDonald C.

Ir J Psychol Med. 2019 Dec;36(4):259-263. doi: 10.1017/ipm.2017.28. Epub 2017 Jul 18.


BK nephropathy as a cause of renal dysfunction in an ABO-incompatible liver transplant patient.

Lai C, Bleasel J, McGrath J, Majumdar A, Kirwan P, Anderson L, Strasser S, Gracey D.

Transplantation. 2019 Oct 30. doi: 10.1097/TP.0000000000003044. [Epub ahead of print] No abstract available.


Time to put down the scalpel? The role of surgery in tendinopathy.

Millar NL, Murrell GAC, Kirwan P.

Br J Sports Med. 2019 Oct 25. pii: bjsports-2019-101084. doi: 10.1136/bjsports-2019-101084. [Epub ahead of print] No abstract available.


How does surgery compare to sham surgery or physiotherapy as a treatment for tendinopathy? A systematic review of randomised trials.

Challoumas D, Clifford C, Kirwan P, Millar NL.

BMJ Open Sport Exerc Med. 2019 Apr 24;5(1):e000528. doi: 10.1136/bmjsem-2019-000528. eCollection 2019.


POMC processing in the hypothalamus is directly regulated by saturated fat - implications for the development of obesity.

Razolli D, de Araújo T, Sant'Ana M, Kirwan P, Cintra D, Merkle F, Velloso L.

Neuroendocrinology. 2019 May 20. doi: 10.1159/000501023. [Epub ahead of print]


HIV care cost in England: a cross-sectional analysis of antiretroviral treatment and the impact of generic introduction.

Ong KJ, van Hoek AJ, Harris RJ, Figueroa J, Waters L, Chau C, Croxford S, Kirwan P, Brown A, Postma MJ, Gill ON, Delpech V.

HIV Med. 2019 Jul;20(6):377-391. doi: 10.1111/hiv.12725. Epub 2019 Apr 29.


Predictive factors for HIV infection among men who have sex with men and who are seeking PrEP: a secondary analysis of the PROUD trial.

White E, Dunn DT, Desai M, Gafos M, Kirwan P, Sullivan AK, Clarke A, McCormack S; PROUD study group.

Sex Transm Infect. 2019 Sep;95(6):449-454. doi: 10.1136/sextrans-2018-053808. Epub 2019 Mar 27.


Extending Bayesian back-calculation to estimate age and time specific HIV incidence.

Brizzi F, Birrell PJ, Plummer MT, Kirwan P, Brown AE, Delpech VC, Gill ON, De Angelis D.

Lifetime Data Anal. 2019 Oct;25(4):757-780. doi: 10.1007/s10985-019-09465-1. Epub 2019 Feb 27.


HIV coinfection among persons diagnosed with hepatitis B in England in 2008-2014.

Ireland G, Simmons R, Balogun K, Kirwan P, Sabin CA, Ramsay M, Delpech V, Mandal S.

HIV Med. 2019 Apr;20(4):255-263. doi: 10.1111/hiv.12707. Epub 2019 Jan 28.


Determining the Origins of Human Immunodeficiency Virus Type 1 Drug-resistant Minority Variants in People Who Are Recently Infected Using Phylogenetic Reconstruction.

Mbisa JL, Kirwan P, Tostevin A, Ledesma J, Bibby DF, Brown A, Myers R, Hassan AS, Murphy G, Asboe D, Pozniak A, Kirk S, Gill ON, Sabin C, Delpech V, Dunn DT; UK HIV Drug Resistance Database .

Clin Infect Dis. 2019 Sep 13;69(7):1136-1143. doi: 10.1093/cid/ciy1048.


Topical glyceryl trinitrate for the treatment of tendinopathies: a systematic review.

Challoumas D, Kirwan PD, Borysov D, Clifford C, McLean M, Millar NL.

Br J Sports Med. 2019 Feb;53(4):251-262. doi: 10.1136/bjsports-2018-099552. Epub 2018 Oct 9.


Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis.

Kirwan P, Kay RG, Brouwers B, Herranz-Pérez V, Jura M, Larraufie P, Jerber J, Pembroke J, Bartels T, White A, Gribble FM, Reimann F, Farooqi IS, O'Rahilly S, Merkle FT.

Mol Metab. 2018 Nov;17:82-97. doi: 10.1016/j.molmet.2018.08.006. Epub 2018 Aug 21.


Prevalence of diagnosed HIV infection among persons with hepatitis C virus infection: England, 2008-2014.

Ireland G, Delpech V, Kirwan P, Croxford S, Lattimore S, Sabin C, Porter K, Mandal S, Simmons R.

HIV Med. 2018 Nov;19(10):708-715. doi: 10.1111/hiv.12662. Epub 2018 Jul 26.


Towards elimination of HIV transmission, AIDS and HIV-related deaths in the UK.

Brown AE, Nash S, Connor N, Kirwan PD, Ogaz D, Croxford S, Angelis D, Delpech VC.

HIV Med. 2018 Jun 20. doi: 10.1111/hiv.12617. [Epub ahead of print] Erratum in: HIV Med. 2019 Jan;20(1):74-76.


The people living with HIV stigma survey UK 2015: HIV-related sexual rejection and other experiences of stigma and discrimination among gay and heterosexual men.

Hibbert M, Crenna-Jennings W, Kirwan P, Benton L, Lut I, Okala S, Asboe D, Jeffries J, Kunda C, Mbewe R, Morris S, Morton J, Nelson M, Thorley L, Paterson H, Ross M, Reeves I, Sharp L, Sseruma W, Valiotis G, Wolton A, Jamal Z, Hudson A, Delpech V.

AIDS Care. 2018 Sep;30(9):1189-1196. doi: 10.1080/09540121.2018.1479027. Epub 2018 May 27.


Where do we diagnose HIV infection? Monitoring new diagnoses made in nontraditional settings in England, Wales and Northern Ireland.

Croxford S, Yin Z, Kall M, Burns F, Simmons R, Copas A, Ireland G, Kirwan P, Chau C, Delpech V.

HIV Med. 2018 May 9. doi: 10.1111/hiv.12627. [Epub ahead of print]


Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights.

Heeley N, Kirwan P, Darwish T, Arnaud M, Evans ML, Merkle FT, Reimann F, Gribble FM, Blouet C.

Mol Metab. 2018 Apr;10:14-27. doi: 10.1016/j.molmet.2018.01.021. Epub 2018 Feb 7.


Experiences of stigma and discrimination in social and healthcare settings among trans people living with HIV in the UK.

Hibbert M, Wolton A, Crenna-Jennings W, Benton L, Kirwan P, Lut I, Okala S, Ross M, Furegato M, Nambiar K, Douglas N, Roche J, Jeffries J, Reeves I, Nelson M, Weerawardhana C, Jamal Z, Hudson A, Delpech V.

AIDS Care. 2018 Jul;30(7):836-843. doi: 10.1080/09540121.2018.1436687. Epub 2018 Feb 6.


Generation and Characterization of Functional Human Hypothalamic Neurons.

Kirwan P, Jura M, Merkle FT.

Curr Protoc Neurosci. 2017 Oct 24;81:3.33.1-3.33.24. doi: 10.1002/cpns.40.


Injecting drug use predicts active tuberculosis in a national cohort of people living with HIV.

Winter JR, Stagg HR, Smith CJ, Brown AE, Lalor MK, Lipman M, Pozniak A, Skingsley A, Kirwan P, Yin Z, Thomas HL, Delpech V, Abubakar I.

AIDS. 2017 Nov 13;31(17):2403-2413. doi: 10.1097/QAD.0000000000001635.


Fall in new HIV diagnoses among men who have sex with men (MSM) at selected London sexual health clinics since early 2015: testing or treatment or pre-exposure prophylaxis (PrEP)?

Brown AE, Mohammed H, Ogaz D, Kirwan PD, Yung M, Nash SG, Furegato M, Hughes G, Connor N, Delpech VC, Gill ON.

Euro Surveill. 2017 Jun 22;22(25). pii: 30553. doi: 10.2807/1560-7917.ES.2017.22.25.30553.


HIV testing in persons diagnosed with hepatitis B and C.

Ireland G, Ogaz D, Kirwan P, Mandal S, Delpech V, Connor N, Simmons R.

HIV Med. 2018 Mar;19(3):e54-e55. doi: 10.1111/hiv.12525. Epub 2017 Jun 14. No abstract available.


What is the overlap between HIV and shigellosis epidemics in England: further evidence of MSM transmission?

Mohan K, Hibbert M, Rooney G, Canvin M, Childs T, Jenkins C, Simms I, Kirwan P, Delpech V, Yin Z, Hughes G, Field N.

Sex Transm Infect. 2018 Feb;94(1):67-71. doi: 10.1136/sextrans-2016-052962. Epub 2017 May 10.


Insidious Risk of Severe Mycobacterium chimaera Infection in Cardiac Surgery Patients.

Chand M, Lamagni T, Kranzer K, Hedge J, Moore G, Parks S, Collins S, Del Ojo Elias C, Ahmed N, Brown T, Smith EG, Hoffman P, Kirwan P, Mason B, Smith-Palmer A, Veal P, Lalor MK, Bennett A, Walker J, Yeap A, Isidro Carrion Martin A, Dolan G, Bhatt S, Skingsley A, Charlett A, Pearce D, Russell K, Kendall S, Klein AA, Robins S, Schelenz S, Newsholme W, Thomas S, Collyns T, Davies E, McMenamin J, Doherty L, Peto TE, Crook D, Zambon M, Phin N.

Clin Infect Dis. 2017 Feb 1;64(3):335-342. doi: 10.1093/cid/ciw754. Epub 2016 Dec 7. Erratum in: Clin Infect Dis. 2017 Sep 1;65(5):875.


Recognising your fears is the first step to overcoming them.

Kirwan P.

Nurs Stand. 2016 Nov 30;31(14):36.


Fibrosis of the Choroid Plexus Filtration Membrane.

Prineas JW, Parratt JD, Kirwan PD.

J Neuropathol Exp Neurol. 2016 Sep;75(9):855-67. doi: 10.1093/jnen/nlw061. Epub 2016 Jul 21.


Risk of invasive meningococcal disease in children and adults with HIV in England: a population-based cohort study.

Simmons RD, Kirwan P, Beebeejaun K, Riordan A, Borrow R, Ramsay ME, Delpech V, Lattimore S, Ladhani S.

BMC Med. 2015 Dec 9;13:297. doi: 10.1186/s12916-015-0538-6.


Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro.

Kirwan P, Turner-Bridger B, Peter M, Momoh A, Arambepola D, Robinson HP, Livesey FJ.

Development. 2015 Sep 15;142(18):3178-87. doi: 10.1242/dev.123851.


APP metabolism regulates tau proteostasis in human cerebral cortex neurons.

Moore S, Evans LD, Andersson T, Portelius E, Smith J, Dias TB, Saurat N, McGlade A, Kirwan P, Blennow K, Hardy J, Zetterberg H, Livesey FJ.

Cell Rep. 2015 May 5;11(5):689-96. doi: 10.1016/j.celrep.2015.03.068. Epub 2015 Apr 23.


Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia.

Menezes MJ, Guo Y, Zhang J, Riley LG, Cooper ST, Thorburn DR, Li J, Dong D, Li Z, Glessner J, Davis RL, Sue CM, Alexander SI, Arbuckle S, Kirwan P, Keating BJ, Xu X, Hakonarson H, Christodoulou J.

Hum Mol Genet. 2015 Apr 15;24(8):2297-307. doi: 10.1093/hmg/ddu747. Epub 2015 Jan 2.


The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro.

Ali FR, Cheng K, Kirwan P, Metcalfe S, Livesey FJ, Barker RA, Philpott A.

Development. 2014 Jun;141(11):2216-24. doi: 10.1242/dev.106377. Epub 2014 May 12.


'Have you seen what is on Facebook?' The use of social networking software by healthcare professions students.

White J, Kirwan P, Lai K, Walton J, Ross S.

BMJ Open. 2013 Jul 24;3(7). pii: e003013. doi: 10.1136/bmjopen-2013-003013. Print 2013.


"I have the right to a private life": medical students' views about professionalism in a digital world.

Ross S, Lai K, Walton JM, Kirwan P, White JS.

Med Teach. 2013 Oct;35(10):826-31. doi: 10.3109/0142159X.2013.802301. Epub 2013 Jul 5.


Plasma cytokines, chemokines and cellular immune responses in pre-school Nigerian children infected with Plasmodium falciparum.

Noone C, Parkinson M, Dowling DJ, Aldridge A, Kirwan P, Molloy SF, Asaolu SO, Holland C, O'Neill SM.

Malar J. 2013 Jan 7;12:5. doi: 10.1186/1475-2875-12-5.


Ascaris co-infection does not alter malaria-induced anaemia in a cohort of Nigerian preschool children.

Abanyie FA, McCracken C, Kirwan P, Molloy SF, Asaolu SO, Holland CV, Gutman J, Lamb TJ.

Malar J. 2013 Jan 2;12:1. doi: 10.1186/1475-2875-12-1.


Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks.

Shi Y, Kirwan P, Livesey FJ.

Nat Protoc. 2012 Oct;7(10):1836-46. doi: 10.1038/nprot.2012.116. Epub 2012 Sep 13.


A human stem cell model of early Alzheimer's disease pathology in Down syndrome.

Shi Y, Kirwan P, Smith J, MacLean G, Orkin SH, Livesey FJ.

Sci Transl Med. 2012 Mar 7;4(124):124ra29. doi: 10.1126/scitranslmed.3003771. Epub 2012 Feb 15.


Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses.

Shi Y, Kirwan P, Smith J, Robinson HP, Livesey FJ.

Nat Neurosci. 2012 Feb 5;15(3):477-86, S1. doi: 10.1038/nn.3041.


Do nurses and social workers have different values? An exploratory study of the care for older people.

Dunworth M, Kirwan P.

J Interprof Care. 2012 May;26(3):226-31. doi: 10.3109/13561820.2011.645172. Epub 2012 Jan 10.


Tumor necrosis factor α induces a model of preeclampsia in pregnant baboons (Papio hamadryas).

Sunderland NS, Thomson SE, Heffernan SJ, Lim S, Thompson J, Ogle R, McKenzie P, Kirwan PJ, Makris A, Hennessy A.

Cytokine. 2011 Nov;56(2):192-9. doi: 10.1016/j.cyto.2011.06.003. Epub 2011 Jul 6.


Hepatitis C and B testing in English prisons is low but increasing.

Kirwan P, Evans B; Sentinel Surveillance of Hepatitis Testing Study Group, Brant L.

J Public Health (Oxf). 2011 Jun;33(2):197-204. doi: 10.1093/pubmed/fdr011. Epub 2011 Feb 23.


Hepatitis B transmission event in an English prison and the importance of immunization.

Viswanathan U, Beaumont A, O'Moore E, Ramsay M, Tedder R, Ijaz S, Balogun K, Kirwan P.

J Public Health (Oxf). 2011 Jun;33(2):193-6. doi: 10.1093/pubmed/fdq083. Epub 2010 Oct 21.


Impact of repeated four-monthly anthelmintic treatment on Plasmodium infection in preschool children: a double-blind placebo-controlled randomized trial.

Kirwan P, Jackson AL, Asaolu SO, Molloy SF, Abiona TC, Bruce MC, Ranford-Cartwright L, O' Neill SM, Holland CV.

BMC Infect Dis. 2010 Sep 21;10:277. doi: 10.1186/1471-2334-10-277.


Sporadic Cryptosporidium infection in Nigerian children: risk factors with species identification.

Molloy SF, Tanner CJ, Kirwan P, Asaolu SO, Smith HV, Nichols RA, Connelly L, Holland CV.

Epidemiol Infect. 2011 Jun;139(6):946-54. doi: 10.1017/S0950268810001998. Epub 2010 Aug 27.


Identification of a high diversity of Cryptosporidium species genotypes and subtypes in a pediatric population in Nigeria.

Molloy SF, Smith HV, Kirwan P, Nichols RA, Asaolu SO, Connelly L, Holland CV.

Am J Trop Med Hyg. 2010 Apr;82(4):608-13. doi: 10.4269/ajtmh.2010.09-0624.


Developmental age, physical fitness and Toxocara seroprevalence amongst lower-secondary students living in rural areas contaminated with Toxocara eggs.

Jarosz W, Mizgajska-Wiktor H, Kirwan P, Konarski J, Rychlicki W, Wawrzyniak G.

Parasitology. 2010 Jan;137(1):53-63. doi: 10.1017/S0031182009990874. Epub 2009 Aug 20.


Soil-transmitted helminth infections in Nigerian children aged 0-25 months.

Kirwan P, Asaolu SO, Abiona TC, Jackson AL, Smith HV, Holland CV.

J Helminthol. 2009 Sep;83(3):261-6. doi: 10.1017/S0022149X08201252. Epub 2009 Apr 9.


Renal connective tissue growth factor correlates with glomerular basement membrane thickness and prospective albuminuria in a non-human primate model of diabetes: possible predictive marker for incipient diabetic nephropathy.

Thomson SE, McLennan SV, Kirwan PD, Heffernan SJ, Hennessy A, Yue DK, Twigg SM.

J Diabetes Complications. 2008 Jul-Aug;22(4):284-94. doi: 10.1016/j.jdiacomp.2007.07.001. Epub 2008 Apr 16.


Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1.

Makris A, Thornton C, Thompson J, Thomson S, Martin R, Ogle R, Waugh R, McKenzie P, Kirwan P, Hennessy A.

Kidney Int. 2007 May;71(10):977-84. Epub 2007 Mar 21.

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