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A randomized controlled trial to reduce sedentary time in rheumatoid arthritis: protocol and rationale of the Take a STAND for Health study.

Pinto AJ, Peçanha T, Meireles K, Benatti FB, Bonfiglioli K, de Sá Pinto AL, Lima FR, Pereira RMR, Irigoyen MCC, Turner JE, Kirwan JP, Owen N, Dunstan DW, Roschel H, Gualano B.

Trials. 2020 Feb 12;21(1):171. doi: 10.1186/s13063-020-4104-y.


Exercise Training Rapidly Increases Hepatic Insulin Extraction in NAFLD.

Hari A, Fealy CE, Axelrod CL, Haus JM, Flask CA, McCullough AJ, Kirwan JP.

Med Sci Sports Exerc. 2020 Feb 5. doi: 10.1249/MSS.0000000000002273. [Epub ahead of print]


Extraocular Vision in a Brittle Star Is Mediated by Chromatophore Movement in Response to Ambient Light.

Sumner-Rooney L, Kirwan JD, Lowe E, Ullrich-Lüter E.

Curr Biol. 2020 Jan 20;30(2):319-327.e4. doi: 10.1016/j.cub.2019.11.042. Epub 2020 Jan 2.


How do different lighting conditions affect the vision and quality of life of people with glaucoma? A systematic review.

Enoch J, Jones L, Taylor DJ, Bronze C, Kirwan JF, Jones PR, Crabb DP.

Eye (Lond). 2020 Jan;34(1):138-154. doi: 10.1038/s41433-019-0679-5. Epub 2019 Dec 10. Review.


Radiation treatment of soft palate squamous cell carcinoma.

Rapp CT, Chera BS, Morris CG, Amdur RJ, Kirwan JM, Mendenhall WM.

Head Neck. 2020 Mar;42(3):530-538. doi: 10.1002/hed.26035. Epub 2019 Nov 27.


UCC118 supplementation reduces exercise-induced gastrointestinal permeability and remodels the gut microbiome in healthy humans.

Axelrod CL, Brennan CJ, Cresci G, Paul D, Hull M, Fealy CE, Kirwan JP.

Physiol Rep. 2019 Nov;7(22):e14276. doi: 10.14814/phy2.14276.


Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs.

Lorenz M, Blaschke B, Benn A, Hammer E, Witt E, Kirwan J, Fritsche-Guenther R, Gloaguen Y, Bartsch C, Vietzke A, Kramer F, Kappert K, Brunner P, Nguyen HG, Dreger H, Stangl K, Knaus P, Stangl V.

Atherosclerosis. 2019 Dec;291:99-106. doi: 10.1016/j.atherosclerosis.2019.10.007. Epub 2019 Oct 10.


Erratum for "Comparison of modified Matyash method to conventional solvent systems for polar metabolite and lipid extractions" [Anal. Chim. Acta 1037 (2018) 301-315].

Sostare E, Di Guida R, Kirwan J, Chalal K, Palmer E, Dunn WB, Viant MR.

Anal Chim Acta. 2019 Dec 24;1091:169. doi: 10.1016/j.aca.2019.09.069. Epub 2019 Oct 16. No abstract available.


Does the Incidence of Treatment-Related Toxicity Plateau After Radiation Therapy: The Long-Term Impact of Integral Dose in Hodgkin's Lymphoma Survivors.

Holtzman AL, Stahl JM, Zhu S, Morris CG, Hoppe BS, Kirwan JE, Mendenhall NP.

Adv Radiat Oncol. 2019 Jul 23;4(4):699-705. doi: 10.1016/j.adro.2019.07.010. eCollection 2019 Oct-Dec.


A millipede compound eye mediating low-resolution vision.

Kirwan JD, Nilsson DE.

Vision Res. 2019 Dec;165:36-44. doi: 10.1016/j.visres.2019.09.003. Epub 2019 Oct 14.


Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.

Helsley RN, Varadharajan V, Brown AL, Gromovsky AD, Schugar RC, Ramachandiran I, Fung K, Kabbany MN, Banerjee R, Neumann CK, Finney C, Pathak P, Orabi D, Osborn LJ, Massey W, Zhang R, Kadam A, Sansbury BE, Pan C, Sacks J, Lee RG, Crooke RM, Graham MJ, Lemieux ME, Gogonea V, Kirwan JP, Allende DS, Civelek M, Fox PL, Rudel LL, Lusis AJ, Spite M, Brown JM.

Elife. 2019 Oct 17;8. pii: e49882. doi: 10.7554/eLife.49882.


Group cognitive-behavioural programme to reduce the impact of rheumatoid arthritis fatigue: the RAFT RCT with economic and qualitative evaluations.

Hewlett S, Almeida C, Ambler N, Blair PS, Choy E, Dures E, Hammond A, Hollingworth W, Kadir B, Kirwan J, Plummer Z, Rooke C, Thorn J, Turner N, Pollock J.

Health Technol Assess. 2019 Oct;23(57):1-130. doi: 10.3310/hta23570.


A novel treatment in the management of genital ulceration in Behçet's disease.

Benson RM, Kirwan J, Moots RJ.

Clin Exp Rheumatol. 2019 Nov-Dec;37 Suppl 121(6):158. Epub 2019 Oct 2. No abstract available.


Sleep, quality of life, and depression in endometrial cancer survivors with obesity seeking weight loss.

Nock NL, Dimitropoulos A, Zanotti KM, Waggoner S, Nagel C, Golubic M, Michener CM, Kirwan JP, Alberts J.

Support Care Cancer. 2019 Sep 2. doi: 10.1007/s00520-019-05051-1. [Epub ahead of print]


WiPP: Workflow for Improved Peak Picking for Gas Chromatography-Mass Spectrometry (GC-MS) Data.

Borgsmüller N, Gloaguen Y, Opialla T, Blanc E, Sicard E, Royer AL, Le Bizec B, Durand S, Migné C, Pétéra M, Pujos-Guillot E, Giacomoni F, Guitton Y, Beule D, Kirwan J.

Metabolites. 2019 Aug 21;9(9). pii: E171. doi: 10.3390/metabo9090171.


Non-invasive assessment of hepatic lipid subspecies matched with non-alcoholic fatty liver disease phenotype.

Erickson ML, Haus JM, Malin SK, Flask CA, McCullough AJ, Kirwan JP.

Nutr Metab Cardiovasc Dis. 2019 Nov;29(11):1197-1204. doi: 10.1016/j.numecd.2019.06.012. Epub 2019 Jun 21.


Exercise Mitigates Bone Loss in Women With Severe Obesity After Roux-en-Y Gastric Bypass: A Randomized Controlled Trial.

Murai IH, Roschel H, Dantas WS, Gil S, Merege-Filho C, de Cleva R, de Sá-Pinto AL, Lima F, Santo MA, Benatti FB, Kirwan JP, Pereira RM, Gualano B.

J Clin Endocrinol Metab. 2019 Oct 1;104(10):4639-4650. doi: 10.1210/jc.2019-00074.


Cardiovascular Biomarkers After Metabolic Surgery Versus Medical Therapy for Diabetes.

Bhatt DL, Aminian A, Kashyap SR, Kirwan JP, Wolski K, Brethauer SA, Hazen SL, Nissen SE, Schauer PR.

J Am Coll Cardiol. 2019 Jul 16;74(2):261-263. doi: 10.1016/j.jacc.2019.04.058. No abstract available.


Combining computer vision and deep learning to enable ultra-scale aerial phenotyping and precision agriculture: A case study of lettuce production.

Bauer A, Bostrom AG, Ball J, Applegate C, Cheng T, Laycock S, Rojas SM, Kirwan J, Zhou J.

Hortic Res. 2019 Jun 1;6:70. doi: 10.1038/s41438-019-0151-5. eCollection 2019.


Biobanking for Metabolomics and Lipidomics in Precision Medicine.

Kirwan JA, Kaddurah-Daouk R, Mitchell T, Pischon T, Schmidt MA, Velagapudi V.

Clin Chem. 2019 Jul;65(7):827-832. doi: 10.1373/clinchem.2018.298620. Epub 2019 May 14. No abstract available.


Developing a group intervention to manage fatigue in rheumatoid arthritis through modifying physical activity.

Salmon VE, Hewlett S, Walsh NE, Kirwan JR, Morris M, Urban M, Cramp F.

BMC Musculoskelet Disord. 2019 May 4;20(1):194. doi: 10.1186/s12891-019-2558-4.


Psychometric properties and cross-language equivalence of the revised Bristol Rheumatoid Arthritis Fatigue and the Rheumatoid Arthritis Impact of Disease scales in rheumatoid arthritis.

Oude Voshaar MAH, Bode C, Hewlett S, Kirwan J, Gossec L, van de Laar MAFJ.

Qual Life Res. 2019 Sep;28(9):2543-2552. doi: 10.1007/s11136-019-02188-8. Epub 2019 Apr 26.


Practical guidance for engaging patients in health research, treatment guidelines and regulatory processes: results of an expert group meeting organized by the World Health Organization (WHO) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).

de Wit M, Cooper C, Tugwell P, Bere N, Kirwan J, Conaghan PG, Roberts C, Aujoulat I, Al-Daghri N, Araujo de Carvalho I, Barker M, Bedlington N, Brandi ML, Bruyère O, Burlet N, Halbout P, Hiligsmann M, Jiwa F, Kanis JA, Laslop A, Lawrence W, Pinto D, Prieto Yerro C, Rabenda V, Rizzoli R, Scholte-Voshaar M, Vlaskovska M, Reginster JY.

Aging Clin Exp Res. 2019 Jul;31(7):905-915. doi: 10.1007/s40520-019-01193-8. Epub 2019 Apr 16. Review.


Skeletal muscle Nur77 and NOR1 insulin responsiveness is blunted in obesity and type 2 diabetes but improved after exercise training.

Mey JT, Solomon TPJ, Kirwan JP, Haus JM.

Physiol Rep. 2019 Mar;7(6):e14042. doi: 10.14814/phy2.14042.


Exercise training promotes a GDF15-associated reduction in fat mass in older adults with obesity.

Zhang H, Fealy CE, Kirwan JP.

Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E829-E836. doi: 10.1152/ajpendo.00439.2018. Epub 2019 Mar 12.


SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology.

Malik AR, Szydlowska K, Nizinska K, Asaro A, van Vliet EA, Popp O, Dittmar G, Fritsche-Guenther R, Kirwan JA, Nykjaer A, Lukasiuk K, Aronica E, Willnow TE.

Cell Rep. 2019 Mar 5;26(10):2792-2804.e6. doi: 10.1016/j.celrep.2019.02.027.


Gastric Bypass Surgery Improves the Skeletal Muscle Ceramide/S1P Ratio and Upregulates the AMPK/ SIRT1/ PGC-1α Pathway in Zucker Diabetic Fatty Rats.

Huang H, Aminian A, Hassan M, Dan O, Axelrod CL, Schauer PR, Brethauer SA, Kirwan JP.

Obes Surg. 2019 Jul;29(7):2158-2165. doi: 10.1007/s11695-019-03800-z.


Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT).

Hewlett S, Almeida C, Ambler N, Blair PS, Choy EH, Dures E, Hammond A, Hollingworth W, Kadir B, Kirwan JR, Plummer Z, Rooke C, Thorn J, Turner N, Pollock J; RAFT Study Group.

Ann Rheum Dis. 2019 Apr;78(4):465-472. doi: 10.1136/annrheumdis-2018-214469. Epub 2019 Feb 6.


A Whole-Grain Diet Increases Glucose-Stimulated Insulin Secretion Independent of Gut Hormones in Adults at Risk for Type 2 Diabetes.

Malin SK, Kullman EL, Scelsi AR, Godin JP, Ross AB, Kirwan JP.

Mol Nutr Food Res. 2019 Apr;63(7):e1800967. doi: 10.1002/mnfr.201800967. Epub 2019 Mar 20.


Medical marijuana-an obesity problem or opportunity?

Greenway FL, Kirwan JP.

Int J Obes (Lond). 2019 Apr;43(4):761-762. doi: 10.1038/s41366-019-0334-z. Epub 2019 Feb 12. No abstract available.


The historical context and scientific legacy of John O. Holloszy.

Hagberg JM, Coyle EF, Baldwin KM, Cartee GD, Fontana L, Joyner MJ, Kirwan JP, Seals DR, Weiss EP.

J Appl Physiol (1985). 2019 Aug 1;127(2):277-305. doi: 10.1152/japplphysiol.00669.2018. Epub 2019 Feb 7.


Survival of women with early-stage cervical cancer in the UK treated with minimal access and open surgery.

Martin-Hirsch P, Wood N, Whitham NL, Macdonald R, Kirwan J, Anagnostopoulos A, Hutson R, Theophilou G, Otify M, Smith M, Myriokefalitaki E, Quinland W, Mahon-Daly F, Clayton RD, Nagar H, Harley I, Dobbs S, Ratnavelu N, Kucukmetin A, Fisher AD, Tailor A, Butler-Manuel S, Madhuri K, Edmondson RJ.

BJOG. 2019 Jul;126(8):956-959. doi: 10.1111/1471-0528.15617. Epub 2019 Mar 1. No abstract available.


Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults.

Erickson ML, Malin SK, Wang Z, Brown JM, Hazen SL, Kirwan JP.

Nutrients. 2019 Jan 16;11(1). pii: E179. doi: 10.3390/nu11010179.


Exercise-induced improvements in glucose effectiveness are blunted by a high glycemic diet in adults with prediabetes.

Hari A, Fealy C, Solomon TPJ, Haus JM, Kelly KR, Barkoukis H, Kirwan JP.

Acta Diabetol. 2019 Feb;56(2):211-217. doi: 10.1007/s00592-018-1272-2. Epub 2019 Jan 5.


Orienting to polarized light at night - matching lunar skylight to performance in a nocturnal beetle.

Foster JJ, Kirwan JD, El Jundi B, Smolka J, Khaldy L, Baird E, Byrne MJ, Nilsson DE, Johnsen S, Dacke M.

J Exp Biol. 2019 Jan 28;222(Pt 2). pii: jeb188532. doi: 10.1242/jeb.188532.


Is GH nadir during OGTT a reliable test for diagnosis of acromegaly in patients with abnormal glucose metabolism?

Dobri G, Niwattisaiwong S, Bena JF, Gupta M, Kirwan J, Kennedy L, Hamrahian AH.

Endocrine. 2019 Apr;64(1):139-146. doi: 10.1007/s12020-018-1805-z. Epub 2018 Nov 10.


Exercise training remodels human skeletal muscle mitochondrial fission and fusion machinery towards a pro-elongation phenotype.

Axelrod CL, Fealy CE, Mulya A, Kirwan JP.

Acta Physiol (Oxf). 2019 Apr;225(4):e13216. doi: 10.1111/apha.13216. Epub 2018 Dec 1.


Reversal of Improved Endothelial Function After Bariatric Surgery Is Mitigated by Exercise Training.

Dantas WS, Gil S, Murai IH, Costa-Hong V, Peçanha T, Merege-Filho CAA, de Sá-Pinto AL, de Cleva R, Santo MA, Pereira RMR, Kirwan JP, Roschel H, Gualano B.

J Am Coll Cardiol. 2018 Oct 30;72(18):2278-2279. doi: 10.1016/j.jacc.2018.07.094. No abstract available.


Comparison of modified Matyash method to conventional solvent systems for polar metabolite and lipid extractions.

Sostare J, Di Guida R, Kirwan J, Chalal K, Palmer E, Dunn WB, Viant MR.

Anal Chim Acta. 2018 Dec 11;1037:301-315. doi: 10.1016/j.aca.2018.03.019. Epub 2018 Apr 5. Erratum in: Anal Chim Acta. 2019 Dec 24;1091:169.


Mitochondrial dynamics in skeletal muscle insulin resistance and type 2 diabetes.

Fealy CE, Mulya A, Axelrod CL, Kirwan JP.

Transl Res. 2018 Dec;202:69-82. doi: 10.1016/j.trsl.2018.07.011. Epub 2018 Jul 31. Review.


Correction: Low-resolution vision in a velvet worm (Onychophora) (doi: 10.1242/jeb.175802).

Kirwan JD, Graf J, Smolka J, Mayer G, Henze MJ, Nilsson DE.

J Exp Biol. 2018 Jul 1;221(Pt 13). pii: jeb186551. doi: 10.1242/jeb.186551. No abstract available.


Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for "Precision Medicine and Pharmacometabolomics Task Group"-The Metabolomics Society Initiative).

Kirwan JA, Brennan L, Broadhurst D, Fiehn O, Cascante M, Dunn WB, Schmidt MA, Velagapudi V.

Clin Chem. 2018 Aug;64(8):1158-1182. doi: 10.1373/clinchem.2018.287045. Epub 2018 Jun 19. Review.


Mechanisms Responsible for Metabolic Improvements of Bariatric Surgeries.

Kirwan JP, Münzberg H, Berthoud HR.

Diabetes. 2018 Jun;67(6):1043-1044. doi: 10.2337/dbi18-0011. No abstract available.


Weight loss interventions for adults with overweight/obesity and chronic musculoskeletal pain: a mixed methods systematic review.

Cooper L, Ryan CG, Ells LJ, Hamilton S, Atkinson G, Cooper K, Johnson MI, Kirwan JP, Martin D.

Obes Rev. 2018 Jul;19(7):989-1007. doi: 10.1111/obr.12686. Epub 2018 May 20.


Functional high-intensity exercise training ameliorates insulin resistance and cardiometabolic risk factors in type 2 diabetes.

Fealy CE, Nieuwoudt S, Foucher JA, Scelsi AR, Malin SK, Pagadala M, Cruz LA, Li M, Rocco M, Burguera B, Kirwan JP.

Exp Physiol. 2018 Jul;103(7):985-994. doi: 10.1113/EP086844.


The sea urchin Diadema africanum uses low resolution vision to find shelter and deter enemies.

Kirwan JD, Bok MJ, Smolka J, Foster JJ, Hernández JC, Nilsson DE.

J Exp Biol. 2018 Jul 16;221(Pt 14). pii: jeb176271. doi: 10.1242/jeb.176271.


2-Octylcyanoacrylate for the prevention of anastomotic leak.

Costales AB, Patil D, Mulya A, Kirwan JP, Michener CM.

J Surg Res. 2018 Jun;226:166-172. doi: 10.1016/j.jss.2018.01.026. Epub 2018 Feb 22.


Low--resolution vision in a velvet worm (Onychophora).

Kirwan JD, Graf J, Smolka J, Mayer G, Henze MJ, Nilsson DE.

J Exp Biol. 2018 Jun 4;221(Pt 11). pii: jeb175802. doi: 10.1242/jeb.175802. Erratum in: J Exp Biol. 2018 Jul 1;221(Pt 13):.


Re: Schlenker et al.: Efficacy, safety, and risk factors for failure of standalone ab interno gelatin microstent implantation versus standalone trabeculectomy. (Ophthalmology. 2017;124:1579-1588).

Kirwan J, Lockwood A, Shah P, Broadway D, McNaught A, King A.

Ophthalmology. 2018 Apr;125(4):e25. doi: 10.1016/j.ophtha.2017.11.028. No abstract available.


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