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Items: 10

1.

Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo.

Xu Y, Huang L, Kirschman JL, Vanover DA, Tiwari PM, Santangelo PJ, Shen X, Russell DG.

J Immunol. 2019 Jan 15;202(2):608-617. doi: 10.4049/jimmunol.1800924. Epub 2018 Dec 12.

PMID:
30541883
2.

Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection.

Tiwari PM, Vanover D, Lindsay KE, Bawage SS, Kirschman JL, Bhosle S, Lifland AW, Zurla C, Santangelo PJ.

Nat Commun. 2018 Oct 1;9(1):3999. doi: 10.1038/s41467-018-06508-3.

3.

High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.

Sago CD, Lokugamage MP, Paunovska K, Vanover DA, Monaco CM, Shah NN, Gamboa Castro M, Anderson SE, Rudoltz TG, Lando GN, Munnilal Tiwari P, Kirschman JL, Willett N, Jang YC, Santangelo PJ, Bryksin AV, Dahlman JE.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9944-E9952. doi: 10.1073/pnas.1811276115. Epub 2018 Oct 1. Erratum in: Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11427.

4.

In Vitro Transcribed mRNA Vaccines with Programmable Stimulation of Innate Immunity.

Loomis KH, Lindsay KE, Zurla C, Bhosle SM, Vanover DA, Blanchard EL, Kirschman JL, Bellamkonda RV, Santangelo PJ.

Bioconjug Chem. 2018 Sep 19;29(9):3072-3083. doi: 10.1021/acs.bioconjchem.8b00443. Epub 2018 Aug 13.

PMID:
30067354
5.

Unifying in vitro and in vivo IVT mRNA expression discrepancies in skeletal muscle via mechanotransduction.

Bhosle SM, Loomis KH, Kirschman JL, Blanchard EL, Vanover DA, Zurla C, Habrant D, Edwards D, Baumhof P, Pitard B, Santangelo PJ.

Biomaterials. 2018 Mar;159:189-203. doi: 10.1016/j.biomaterials.2018.01.010. Epub 2018 Jan 6.

PMID:
29331806
6.

RSV glycoprotein and genomic RNA dynamics reveal filament assembly prior to the plasma membrane.

Vanover D, Smith DV, Blanchard EL, Alonas E, Kirschman JL, Lifland AW, Zurla C, Santangelo PJ.

Nat Commun. 2017 Sep 22;8(1):667. doi: 10.1038/s41467-017-00732-z.

7.

Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA-protein correlations at the level of single cells.

Kirschman JL, Bhosle S, Vanover D, Blanchard EL, Loomis KH, Zurla C, Murray K, Lam BC, Santangelo PJ.

Nucleic Acids Res. 2017 Jul 7;45(12):e113. doi: 10.1093/nar/gkx290.

8.

Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide.

Udhayakumar VK, De Beuckelaer A, McCaffrey J, McCrudden CM, Kirschman JL, Vanover D, Van Hoecke L, Roose K, Deswarte K, De Geest BG, Lienenklaus S, Santangelo PJ, Grooten J, McCarthy HO, De Koker S.

Adv Healthc Mater. 2017 Jul;6(13). doi: 10.1002/adhm.201601412. Epub 2017 Apr 24.

PMID:
28436620
9.

Computing in mammalian cells with nucleic acid strand exchange.

Groves B, Chen YJ, Zurla C, Pochekailov S, Kirschman JL, Santangelo PJ, Seelig G.

Nat Nanotechnol. 2016 Mar;11(3):287-294. doi: 10.1038/nnano.2015.278. Epub 2015 Dec 21.

10.

A dedicated superbend x-ray microdiffraction beamline for materials, geo-, and environmental sciences at the advanced light source.

Kunz M, Tamura N, Chen K, MacDowell AA, Celestre RS, Church MM, Fakra S, Domning EE, Glossinger JM, Kirschman JL, Morrison GY, Plate DW, Smith BV, Warwick T, Yashchuk VV, Padmore HA, Ustundag E.

Rev Sci Instrum. 2009 Mar;80(3):035108. doi: 10.1063/1.3096295.

PMID:
19334953

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