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Items: 1 to 50 of 379

1.

Tracing Tumor Evolution in Sarcoma Reveals Clonal Origin of Advanced Metastasis.

Tang YJ, Huang J, Tsushima H, Ban GI, Zhang H, Oristian KM, Puviindran V, Williams N, Ding X, Ou J, Jung SH, Lee CL, Jiao Y, Chen BJ, Kirsch DG, Alman BA.

Cell Rep. 2019 Sep 10;28(11):2837-2850.e5. doi: 10.1016/j.celrep.2019.08.029.

PMID:
31509746
2.

Disruption in Health Care (and Sleep Medicine): "It's the End of the World as We Know it…and I Feel Fine."

Kirsch DB.

J Clin Sleep Med. 2019 Aug 12. pii: jc-19-00390. [Epub ahead of print] No abstract available.

PMID:
31482817
3.

Association of Positive Airway Pressure Use With Acute Care Utilization and Costs.

Kirsch DB, Yang H, Maslow AL, Stolzenbach M, McCall A.

J Clin Sleep Med. 2019 Aug 19. pii: jc-18-00771. [Epub ahead of print]

PMID:
31482806
4.

Neutrophils promote tumor resistance to radiation therapy.

Wisdom AJ, Hong CS, Lin AJ, Xiang Y, Cooper DE, Zhang J, Xu ES, Kuo HC, Mowery YM, Carpenter DJ, Kadakia KT, Himes JE, Luo L, Ma Y, Williams N, Cardona DM, Haldar M, Diao Y, Markovina S, Schwarz JK, Kirsch DG.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18584-18589. doi: 10.1073/pnas.1901562116. Epub 2019 Aug 28.

PMID:
31462499
5.

The Fusion Oncogene FUS-CHOP Drives Sarcomagenesis of High-Grade Spindle Cell Sarcomas in Mice.

Chen M, Xu ES, Leisenring NH, Cardona DM, Luo L, Ma Y, Ventura A, Kirsch DG.

Sarcoma. 2019 Jul 25;2019:1340261. doi: 10.1155/2019/1340261. eCollection 2019.

6.

Establishing the Impact of Vascular Damage on Tumor Response to High-Dose Radiation Therapy.

Castle KD, Kirsch DG.

Cancer Res. 2019 Aug 19. pii: canres.1323.2019. doi: 10.1158/0008-5472.CAN-19-1323. [Epub ahead of print]

PMID:
31427377
7.

Dietary methionine influences therapy in mouse cancer models and alters human metabolism.

Gao X, Sanderson SM, Dai Z, Reid MA, Cooper DE, Lu M, Richie JP Jr, Ciccarella A, Calcagnotto A, Mikhael PG, Mentch SJ, Liu J, Ables G, Kirsch DG, Hsu DS, Nichenametla SN, Locasale JW.

Nature. 2019 Aug;572(7769):397-401. doi: 10.1038/s41586-019-1437-3. Epub 2019 Jul 31.

PMID:
31367041
8.

Stable Multimetallic Nanoparticles for Oxygen Electrocatalysis.

Lacey SD, Dong Q, Huang Z, Luo J, Xie H, Lin Z, Kirsch DJ, Vattipalli V, Povinelli C, Fan W, Shahbazian-Yassar R, Wang D, Hu L.

Nano Lett. 2019 Aug 14;19(8):5149-5158. doi: 10.1021/acs.nanolett.9b01523. Epub 2019 Jul 17.

PMID:
31313586
9.

Diplopia and proptosis due to isolated lateral rectus plasmacytoma in a patient with multiple myeloma.

Saffra N, Gorgani F, Panasci D, Kirsch D.

BMJ Case Rep. 2019 Jul 8;12(7). pii: e229178. doi: 10.1136/bcr-2018-229178.

PMID:
31289159
10.

Sensitization of Vascular Endothelial Cells to Ionizing Radiation Promotes the Development of Delayed Intestinal Injury in Mice.

Lee CL, Daniel AR, Holbrook M, Brownstein J, Silva Campos LD, Hasapis S, Ma Y, Borst LB, Badea CT, Kirsch DG.

Radiat Res. 2019 Sep;192(3):258-266. doi: 10.1667/RR15371.1. Epub 2019 Jul 2.

PMID:
31265788
11.

Insights into pediatric rhabdomyosarcoma research: Challenges and goals.

Yohe ME, Heske CM, Stewart E, Adamson PC, Ahmed N, Antonescu CR, Chen E, Collins N, Ehrlich A, Galindo RL, Gryder BE, Hahn H, Hammond S, Hatley ME, Hawkins DS, Hayes MN, Hayes-Jordan A, Helman LJ, Hettmer S, Ignatius MS, Keller C, Khan J, Kirsch DG, Linardic CM, Lupo PJ, Rota R, Shern JF, Shipley J, Sindiri S, Tapscott SJ, Vakoc CR, Wexler LH, Langenau DM.

Pediatr Blood Cancer. 2019 Oct;66(10):e27869. doi: 10.1002/pbc.27869. Epub 2019 Jun 21. Review.

PMID:
31222885
12.

Safely combining trabectedin with radiotherapy to treat myxoid liposarcoma.

Chen M, Kirsch DG.

EClinicalMedicine. 2019 Mar 31;9:5-6. doi: 10.1016/j.eclinm.2019.03.015. eCollection 2019 Mar. No abstract available.

13.

Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma.

Lee CL, Mowery YM, Daniel AR, Zhang D, Sibley AB, Delaney JR, Wisdom AJ, Qin X, Wang X, Caraballo I, Gresham J, Luo L, Van Mater D, Owzar K, Kirsch DG.

JCI Insight. 2019 Jul 11;4(13). pii: 128698. doi: 10.1172/jci.insight.128698.

14.

Public Awareness, Medical Integration, and Innovation in Sleep Medicine.

Kirsch DB, Khosla S.

J Clin Sleep Med. 2019 May 15;15(5):799-801. doi: 10.5664/jcsm.7786. No abstract available.

15.

Bridging the translational gap: Implementation of multimodal small animal imaging strategies for tumor burden assessment in a co-clinical trial.

Blocker SJ, Mowery YM, Holbrook MD, Qi Y, Kirsch DG, Johnson GA, Badea CT.

PLoS One. 2019 Apr 8;14(4):e0207555. doi: 10.1371/journal.pone.0207555. eCollection 2019.

16.

Functional assay to guide precision radiotherapy by assessing individual patient radiosensitivity.

Wisdom AJ, Kirsch DG.

EBioMedicine. 2019 Mar;41:26-27. doi: 10.1016/j.ebiom.2019.03.002. Epub 2019 Mar 7. No abstract available.

17.

Letter to the Editor Regarding the Updated American Academy of Otolaryngology-Head and Neck Surgery Foundation Clinical Practice Guideline on Tonsillectomy in Children.

Lloyd R, Kirsch DB, Carden KA, Malhotra RK, Rosen IM, Ramar K.

J Clin Sleep Med. 2019 Feb 15;15(2):363-365. doi: 10.5664/jcsm.7650. No abstract available.

18.

Investigating a chimeric anti-mouse PDGFRα antibody as a radiosensitizer in primary mouse sarcomas.

Song EJ, Ashcraft KA, Lowery CD, Mowery YM, Luo L, Ma Y, Campos LDS, Cardona DM, Stancato L, Kirsch DG.

EBioMedicine. 2019 Feb;40:224-230. doi: 10.1016/j.ebiom.2019.01.046. Epub 2019 Jan 31.

19.

Consumer Sleep Technologies: How to Balance the Promises of New Technology with Evidence-Based Medicine and Clinical Guidelines.

Khosla S, Deak MC, Gault D, Goldstein CA, Hwang D, Kwon Y, O'Hearn D, Schutte-Rodin S, Yurcheshen M, Kirsch DB.

J Clin Sleep Med. 2019 Jan 15;15(1):163-165. doi: 10.5664/jcsm.7598. No abstract available.

20.

Clinical Use of a Home Sleep Apnea Test: An Updated American Academy of Sleep Medicine Position Statement.

Rosen IM, Kirsch DB, Carden KA, Malhotra RK, Ramar K, Aurora RN, Kristo DA, Martin JL, Olson EJ, Rosen CL, Rowley JA, Shelgikar AV; American Academy of Sleep Medicine Board of Directors.

J Clin Sleep Med. 2018 Dec 15;14(12):2075-2077. doi: 10.5664/jcsm.7540.

21.

Mild Traumatic Brain Injury in Mice Beneficially Alters Lung NK1R and Structural Protein Expression to Enhance Survival after Pseudomonas aeruginosa Infection.

Vaickus M, Hsieh T, Kintsurashvili E, Kim J, Kirsch D, Kasotakis G, Remick DG.

Am J Pathol. 2019 Feb;189(2):295-307. doi: 10.1016/j.ajpath.2018.10.019. Epub 2018 Nov 23.

PMID:
30472211
22.

Arousal-Based Scoring for Obstructive Sleep Apnea.

Malhotra RK, Kirsch DB, Carden KA, Rosen IM, Ramar K.

J Clin Sleep Med. 2018 Nov 15;14(11):1963-1964. doi: 10.5664/jcsm.7508. No abstract available.

23.

Medical Cannabis, Synthetic Marijuana Extracts, and Obstructive Sleep Apnea.

Ramar K, Kirsch DB, Carden KA, Rosen IM, Malhotra RK.

J Clin Sleep Med. 2018 Oct 15;14(10):1815-1816. doi: 10.5664/jcsm.7412. No abstract available.

24.

Injury promotes sarcoma development in a genetically and temporally restricted manner.

Van Mater D, Xu E, Reddy A, Añó L, Sachdeva M, Huang W, Williams N, Ma Y, Love C, Happ L, Dave S, Kirsch DG.

JCI Insight. 2018 Oct 18;3(20). pii: 123687. doi: 10.1172/jci.insight.123687.

25.

Deletion of Atm in Tumor but not Endothelial Cells Improves Radiation Response in a Primary Mouse Model of Lung Adenocarcinoma.

Torok JA, Oh P, Castle KD, Reinsvold M, Ma Y, Luo L, Lee CL, Kirsch DG.

Cancer Res. 2019 Feb 15;79(4):773-782. doi: 10.1158/0008-5472.CAN-17-3103. Epub 2018 Oct 12.

PMID:
30315114
26.

Bone protection by inhibition of microRNA-182.

Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, Greenblatt MB, Mangala LS, Lopez-Berestein G, Kirsch DG, Sood AK, Zhao L, Zhao B.

Nat Commun. 2018 Oct 5;9(1):4108. doi: 10.1038/s41467-018-06446-0.

27.

Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals.

Liu X, Cooper DE, Cluntun AA, Warmoes MO, Zhao S, Reid MA, Liu J, Lund PJ, Lopes M, Garcia BA, Wellen KE, Kirsch DG, Locasale JW.

Cell. 2018 Oct 4;175(2):502-513.e13. doi: 10.1016/j.cell.2018.08.040. Epub 2018 Sep 20.

PMID:
30245009
28.

Multidisciplinary Management of Oligometastatic Soft Tissue Sarcoma.

Grilley-Olson JE, Webber NP, Demos DS, Christensen JD, Kirsch DG.

Am Soc Clin Oncol Educ Book. 2018 May 23;38:939-948. doi: 10.1200/EDBK_200573. Review.

PMID:
30231386
29.

Loss of MST/Hippo Signaling in a Genetically Engineered Mouse Model of Fusion-Positive Rhabdomyosarcoma Accelerates Tumorigenesis.

Oristian KM, Crose LES, Kuprasertkul N, Bentley RC, Lin YT, Williams N, Kirsch DG, Linardic CM.

Cancer Res. 2018 Oct 1;78(19):5513-5520. doi: 10.1158/0008-5472.CAN-17-3912. Epub 2018 Aug 9.

PMID:
30093562
30.

Blocking Cyclin-Dependent Kinase 4/6 During Single Dose Versus Fractionated Radiation Therapy Leads to Opposite Effects on Acute Gastrointestinal Toxicity in Mice.

Lee CL, Oh P, Xu ES, Ma Y, Kim Y, Daniel AR, Kirsch DG.

Int J Radiat Oncol Biol Phys. 2018 Dec 1;102(5):1569-1576. doi: 10.1016/j.ijrobp.2018.07.192. Epub 2018 Jul 26.

31.

Polysomnography for Obstructive Sleep Apnea Should Include Arousal-Based Scoring: An American Academy of Sleep Medicine Position Statement.

Malhotra RK, Kirsch DB, Kristo DA, Olson EJ, Aurora RN, Carden KA, Chervin RD, Martin JL, Ramar K, Rosen CL, Rowley JA, Rosen IM; American Academy of Sleep Medicine Board of Directors.

J Clin Sleep Med. 2018 Jul 15;14(7):1245-1247. doi: 10.5664/jcsm.7234.

32.

Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.

Cheung PF, Neff F, Neander C, Bazarna A, Savvatakis K, Liffers ST, Althoff K, Lee CL, Moding EJ, Kirsch DG, Saur D, Bazhin AV, Trajkovic-Arsic M, Heikenwalder MF, Siveke JT.

Cancer Res. 2018 Sep 1;78(17):4997-5010. doi: 10.1158/0008-5472.CAN-18-0052. Epub 2018 May 29.

33.

Consumer Sleep Technology: An American Academy of Sleep Medicine Position Statement.

Khosla S, Deak MC, Gault D, Goldstein CA, Hwang D, Kwon Y, O'Hearn D, Schutte-Rodin S, Yurcheshen M, Rosen IM, Kirsch DB, Chervin RD, Carden KA, Ramar K, Aurora RN, Kristo DA, Malhotra RK, Martin JL, Olson EJ, Rosen CL, Rowley JA; American Academy of Sleep Medicine Board of Directors.

J Clin Sleep Med. 2018 May 15;14(5):877-880. doi: 10.5664/jcsm.7128.

34.

Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology.

Bristow RG, Alexander B, Baumann M, Bratman SV, Brown JM, Camphausen K, Choyke P, Citrin D, Contessa JN, Dicker A, Kirsch DG, Krause M, Le QT, Milosevic M, Morris ZS, Sarkaria JN, Sondel PM, Tran PT, Wilson GD, Willers H, Wong RKS, Harari PM.

Lancet Oncol. 2018 May;19(5):e240-e251. doi: 10.1016/S1470-2045(18)30096-2. Review.

PMID:
29726389
35.

Current Opportunities and Future Vision of Precision Medicine in Radiation Oncology.

Kirsch DG.

Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):267-270. doi: 10.1016/j.ijrobp.2017.04.005. No abstract available.

36.

Rationale and emerging strategies for immune checkpoint blockade in soft tissue sarcoma.

Wisdom AJ, Mowery YM, Riedel RF, Kirsch DG.

Cancer. 2018 Oct 1;124(19):3819-3829. doi: 10.1002/cncr.31517. Epub 2018 May 3. Review.

PMID:
29723407
37.

Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors.

Peacock JD, Pridgeon MG, Tovar EA, Essenburg CJ, Bowman M, Madaj Z, Koeman J, Boguslawski EA, Grit J, Dodd RD, Khachaturov V, Cardona DM, Chen M, Kirsch DG, Maina F, Dono R, Winn ME, Graveel CR, Steensma MR.

Cancer Res. 2018 Jul 1;78(13):3672-3687. doi: 10.1158/0008-5472.CAN-17-3167. Epub 2018 May 2.

38.

Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches-Meeting Viewpoint.

Ahmed MM, Coleman CN, Mendonca M, Bentzen S, Vikram B, Seltzer SM, Goodhead D, Obcemea C, Mohan R, Prise KM, Capala J, Citrin D, Kao G, Aryankalayil M, Eke I, Buchsbaum JC, Prasanna PGS, Liu FF, Le QT, Teicher B, Kirsch DG, Smart D, Tepper J, Formenti S, Haas-Kogan D, Raben D, Mitchell J.

Cancer Res. 2018 May 1;78(9):2166-2170. doi: 10.1158/0008-5472.CAN-17-3760. Epub 2018 Apr 23. No abstract available.

39.

Correlation of High-Risk Soft Tissue Sarcoma Biomarker Expression Patterns with Outcome following Neoadjuvant Chemoradiation.

Kane JM 3rd, Magliocco A, Zhang Q, Wang D, Klimowicz A, Harris J, Simko J, DeLaney T, Kraybill W, Kirsch DG.

Sarcoma. 2018 Feb 28;2018:8310950. doi: 10.1155/2018/8310950. eCollection 2018.

40.

Mice Lacking RIP3 Kinase are not Protected from Acute Radiation Syndrome.

Castle KD, Daniel AR, Moding EJ, Luo L, Lee CL, Kirsch DG.

Radiat Res. 2018 Jun;189(6):627-633. doi: 10.1667/RR15001.1. Epub 2018 Apr 10.

41.

The Risk of Fatigue and Sleepiness in the Ridesharing Industry: An American Academy of Sleep Medicine Position Statement.

Berneking M, Rosen IM, Kirsch DB, Chervin RD, Carden KA, Ramar K, Aurora RN, Kristo DA, Malhotra RK, Martin JL, Olson EJ, Rosen CL, Rowley JA, Gurubhagavatula I; American Academy of Sleep Medicine Board of Directors.

J Clin Sleep Med. 2018 Apr 15;14(4):683-685. doi: 10.5664/jcsm.7072.

42.

Medical Cannabis and the Treatment of Obstructive Sleep Apnea: An American Academy of Sleep Medicine Position Statement.

Ramar K, Rosen IM, Kirsch DB, Chervin RD, Carden KA, Aurora RN, Kristo DA, Malhotra RK, Martin JL, Olson EJ, Rosen CL, Rowley JA; American Academy of Sleep Medicine Board of Directors.

J Clin Sleep Med. 2018 Apr 15;14(4):679-681. doi: 10.5664/jcsm.7070.

43.

Dual-Energy CT Imaging of Tumor Liposome Delivery After Gold Nanoparticle-Augmented Radiation Therapy.

Ashton JR, Castle KD, Qi Y, Kirsch DG, West JL, Badea CT.

Theranostics. 2018 Feb 12;8(7):1782-1797. doi: 10.7150/thno.22621. eCollection 2018.

44.

Technological Advances, Biologic Rationales, and the Associated Success of Chemotherapy With Hyperthermia in Improved Outcomes in Patients With Sarcoma.

Dewhirst MW, Kirsch D.

JAMA Oncol. 2018 Apr 1;4(4):493-494. doi: 10.1001/jamaoncol.2017.4941. No abstract available.

PMID:
29450459
45.

Characterizing the Potency and Impact of Carbon Ion Therapy in a Primary Mouse Model of Soft Tissue Sarcoma.

Brownstein JM, Wisdom AJ, Castle KD, Mowery YM, Guida P, Lee CL, Tommasino F, Tessa C, Scifoni E, Gao J, Luo L, Campos LDS, Ma Y, Williams N, Jung SH, Durante M, Kirsch DG.

Mol Cancer Ther. 2018 Apr;17(4):858-868. doi: 10.1158/1535-7163.MCT-17-0965. Epub 2018 Feb 7.

46.

Ambient-air ozonolysis of triglycerides in aged fingerprint residues.

Pleik S, Spengler B, Ram Bhandari D, Luhn S, Schäfer T, Urbach D, Kirsch D.

Analyst. 2018 Feb 26;143(5):1197-1209. doi: 10.1039/c7an01506b.

PMID:
29431747
47.

Extrusion-Based 3D Printing of Hierarchically Porous Advanced Battery Electrodes.

Lacey SD, Kirsch DJ, Li Y, Morgenstern JT, Zarket BC, Yao Y, Dai J, Garcia LQ, Liu B, Gao T, Xu S, Raghavan SR, Connell JW, Lin Y, Hu L.

Adv Mater. 2018 Mar;30(12):e1705651. doi: 10.1002/adma.201705651. Epub 2018 Jan 30.

PMID:
29380891
48.

Intraarterial Liver-Directed Therapies: The Role of Interventional Oncology.

Ma J, Gimenez JM, Sandow T, Devun D, Kirsch D, Gulotta P, Gilbert P, Kay D.

Ochsner J. 2017 Winter;17(4):412-416. Review.

49.

Clinical Images: Transjugular Intrahepatic Portosystemic Shunt Reduction for Management of Recurrent Hepatic Encephalopathy.

Khalili H, Goldman D, Frischhertz S, Kirsch D.

Ochsner J. 2017 Winter;17(4):311-316. No abstract available.

50.

Assessment of Response to Transcatheter Arterial Chemoembolization with Doxorubicin-eluting Microspheres: Tumor Biology and Hepatocellular Carcinoma Recurrence in a 5-year Transplant Cohort.

Sandow TA, Arndt SE, Albar AA, DeVun DA, Kirsch DS, Gimenez JM, Bohorquez HE, Gilbert PJ, Thevenot PT, Nunez KG, Galliano GA, Cohen AJ, Kay D, Gulotta PM.

Radiology. 2018 Mar;286(3):1072-1083. doi: 10.1148/radiol.2017170731. Epub 2017 Dec 4.

PMID:
29206595

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