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Items: 1 to 50 of 137

1.

Early identification of unusually clustered mutations and root causes in therapeutic antibody development.

Qian Y, Chen Z, Huang X, Wang X, Xu X, Kirov S, Ludwig R, Qian NX, Ravi K, Tao L, Borys MC, Li ZJ.

Biotechnol Bioeng. 2018 May 19. doi: 10.1002/bit.26728. [Epub ahead of print]

PMID:
29777592
2.

STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.

Skoulidis F, Goldberg ME, Greenawalt DM, Hellmann MD, Awad MM, Gainor JF, Schrock AB, Hartmaier RJ, Trabucco SE, Gay L, Ali SM, Elvin JA, Singal G, Ross JS, Fabrizio D, Szabo PM, Chang H, Sasson A, Srinivasan S, Kirov S, Szustakowski J, Vitazka P, Edwards R, Bufill JA, Sharma N, Ou SI, Peled N, Spigel DR, Rizvi H, Aguilar EJ, Carter BW, Erasmus J, Halpenny DF, Plodkowski AJ, Long NM, Nishino M, Denning WL, Galan-Cobo A, Hamdi H, Hirz T, Tong P, Wang J, Rodriguez-Canales J, Villalobos PA, Parra ER, Kalhor N, Sholl LM, Sauter JL, Jungbluth AA, Mino-Kenudson M, Azimi R, Elamin YY, Zhang J, Leonardi GC, Jiang F, Wong KK, Lee JJ, Papadimitrakopoulou VA, Wistuba II, Miller VA, Frampton GM, Wolchok JD, Shaw AT, Jänne PA, Stephens PJ, Rudin CM, Geese WJ, Albacker LA, Heymach JV.

Cancer Discov. 2018 Jul;8(7):822-835. doi: 10.1158/2159-8290.CD-18-0099. Epub 2018 May 17.

PMID:
29773717
3.

Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine.

Pryazhnikov E, Mugantseva E, Casarotto P, Kolikova J, Fred SM, Toptunov D, Afzalov R, Hotulainen P, Voikar V, Terry-Lorenzo R, Engel S, Kirov S, Castren E, Khiroug L.

Sci Rep. 2018 Apr 24;8(1):6464. doi: 10.1038/s41598-018-24933-8.

4.

NaV channel variants in patients with painful and nonpainful peripheral neuropathy.

Wadhawan S, Pant S, Golhar R, Kirov S, Thompson J, Jacobsen L, Qureshi I, Ajroud-Driss S, Freeman R, Simpson DM, Smith AG, Hoke A, Bristow LJ.

Neurol Genet. 2017 Dec 15;3(6):e207. doi: 10.1212/NXG.0000000000000207. eCollection 2017 Dec.

5.

CRISPR-DAV: CRISPR NGS data analysis and visualization pipeline.

Wang X, Tilford C, Neuhaus I, Mintier G, Guo Q, Feder JN, Kirov S.

Bioinformatics. 2017 Dec 1;33(23):3811-3812. doi: 10.1093/bioinformatics/btx518.

PMID:
28961906
6.

Reversible Disruption of Neuronal Mitochondria by Ischemic and Traumatic Injury Revealed by Quantitative Two-Photon Imaging in the Neocortex of Anesthetized Mice.

Kislin M, Sword J, Fomitcheva IV, Croom D, Pryazhnikov E, Lihavainen E, Toptunov D, Rauvala H, Ribeiro AS, Khiroug L, Kirov SA.

J Neurosci. 2017 Jan 11;37(2):333-348. doi: 10.1523/JNEUROSCI.1510-16.2016.

7.

The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy.

Hartings JA, Shuttleworth CW, Kirov SA, Ayata C, Hinzman JM, Foreman B, Andrew RD, Boutelle MG, Brennan KC, Carlson AP, Dahlem MA, Drenckhahn C, Dohmen C, Fabricius M, Farkas E, Feuerstein D, Graf R, Helbok R, Lauritzen M, Major S, Oliveira-Ferreira AI, Richter F, Rosenthal ES, Sakowitz OW, Sánchez-Porras R, Santos E, Schöll M, Strong AJ, Urbach A, Westover MB, Winkler MK, Witte OW, Woitzik J, Dreier JP.

J Cereb Blood Flow Metab. 2017 May;37(5):1571-1594. doi: 10.1177/0271678X16654495. Epub 2016 Jan 1. Review.

8.

Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.

Dreier JP, Fabricius M, Ayata C, Sakowitz OW, William Shuttleworth C, Dohmen C, Graf R, Vajkoczy P, Helbok R, Suzuki M, Schiefecker AJ, Major S, Winkler MK, Kang EJ, Milakara D, Oliveira-Ferreira AI, Reiffurth C, Revankar GS, Sugimoto K, Dengler NF, Hecht N, Foreman B, Feyen B, Kondziella D, Friberg CK, Piilgaard H, Rosenthal ES, Westover MB, Maslarova A, Santos E, Hertle D, Sánchez-Porras R, Jewell SL, Balança B, Platz J, Hinzman JM, Lückl J, Schoknecht K, Schöll M, Drenckhahn C, Feuerstein D, Eriksen N, Horst V, Bretz JS, Jahnke P, Scheel M, Bohner G, Rostrup E, Pakkenberg B, Heinemann U, Claassen J, Carlson AP, Kowoll CM, Lublinsky S, Chassidim Y, Shelef I, Friedman A, Brinker G, Reiner M, Kirov SA, Andrew RD, Farkas E, Güresir E, Vatter H, Chung LS, Brennan KC, Lieutaud T, Marinesco S, Maas AI, Sahuquillo J, Dahlem MA, Richter F, Herreras O, Boutelle MG, Okonkwo DO, Bullock MR, Witte OW, Martus P, van den Maagdenberg AM, Ferrari MD, Dijkhuizen RM, Shutter LA, Andaluz N, Schulte AP, MacVicar B, Watanabe T, Woitzik J, Lauritzen M, Strong AJ, Hartings JA.

J Cereb Blood Flow Metab. 2017 May;37(5):1595-1625. doi: 10.1177/0271678X16654496. Epub 2016 Jan 1. Review.

9.

Impact of Pre-existing NS5A-L31 or -Y93H Minor Variants on Response Rates in Patients Infected with HCV Genotype-1b Treated with Daclatasvir/Asunaprevir.

Hernandez D, Yu F, Huang X, Kirov S, Pant S, McPhee F.

Adv Ther. 2016 Jul;33(7):1169-79. doi: 10.1007/s12325-016-0354-1. Epub 2016 Jun 10.

PMID:
27287851
10.

Adrenergic activation attenuates astrocyte swelling induced by hypotonicity and neurotrauma.

Vardjan N, Horvat A, Anderson JE, Yu D, Croom D, Zeng X, Lužnik Z, Kreft M, Teng YD, Kirov SA, Zorec R.

Glia. 2016 Jun;64(6):1034-49. doi: 10.1002/glia.22981. Epub 2016 Mar 28.

11.

Neuronal pannexin-1 channels are not molecular routes of water influx during spreading depolarization-induced dendritic beading.

Sword J, Croom D, Wang PL, Thompson RJ, Kirov SA.

J Cereb Blood Flow Metab. 2017 May;37(5):1626-1633. doi: 10.1177/0271678X16639328. Epub 2016 Jan 1.

12.

Chloride Cotransporters as a Molecular Mechanism underlying Spreading Depolarization-Induced Dendritic Beading.

Steffensen AB, Sword J, Croom D, Kirov SA, MacAulay N.

J Neurosci. 2015 Sep 2;35(35):12172-87. doi: 10.1523/JNEUROSCI.0400-15.2015.

13.

Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.

Lenhart R, Kirov S, Desilva H, Cao J, Lei M, Johnston K, Peterson R, Schweizer L, Purandare A, Ross-Macdonald P, Fairchild C, Wong T, Wee S.

Mol Cancer Ther. 2015 Oct;14(10):2167-74. doi: 10.1158/1535-7163.MCT-15-0037. Epub 2015 Aug 7.

14.

Astrocyte contributions to flow/pressure-evoked parenchymal arteriole vasoconstriction.

Kim KJ, Iddings JA, Stern JE, Blanco VM, Croom D, Kirov SA, Filosa JA.

J Neurosci. 2015 May 27;35(21):8245-57. doi: 10.1523/JNEUROSCI.4486-14.2015.

15.

Functional annotation of differentially regulated gene set using WebGestalt: a gene set predictive of response to ipilimumab in tumor biopsies.

Kirov S, Ji R, Wang J, Zhang B.

Methods Mol Biol. 2014;1101:31-42. doi: 10.1007/978-1-62703-721-1_3.

PMID:
24233776
16.

Draft genome sequence of the chronic, nonclonal cystic fibrosis isolate Pseudomonas aeruginosa strain 18A.

Woo JK, McElroy K, Rice SA, Kirov SM, Thomas T, Kjelleberg S.

Genome Announc. 2013 Mar 21;1(2):e0000113. doi: 10.1128/genomeA.00001-13.

17.

Evolution of neuronal and astroglial disruption in the peri-contusional cortex of mice revealed by in vivo two-photon imaging.

Sword J, Masuda T, Croom D, Kirov SA.

Brain. 2013 May;136(Pt 5):1446-61. doi: 10.1093/brain/awt026. Epub 2013 Mar 6.

18.

Is spreading depolarization characterized by an abrupt, massive release of gibbs free energy from the human brain cortex?

Dreier JP, Isele T, Reiffurth C, Offenhauser N, Kirov SA, Dahlem MA, Herreras O.

Neuroscientist. 2013 Feb;19(1):25-42. doi: 10.1177/1073858412453340. Epub 2012 Jul 24.

19.

Persistent astroglial swelling accompanies rapid reversible dendritic injury during stroke-induced spreading depolarizations.

Risher WC, Croom D, Kirov SA.

Glia. 2012 Nov;60(11):1709-20. doi: 10.1002/glia.22390. Epub 2012 Jul 20.

20.

Biofilm dispersal cells of a cystic fibrosis Pseudomonas aeruginosa isolate exhibit variability in functional traits likely to contribute to persistent infection.

Woo JK, Webb JS, Kirov SM, Kjelleberg S, Rice SA.

FEMS Immunol Med Microbiol. 2012 Nov;66(2):251-64. doi: 10.1111/j.1574-695X.2012.01006.x. Epub 2012 Jul 31.

21.

Bundle-forming pilus locus of Aeromonas veronii bv. Sobria.

Hadi N, Yang Q, Barnett TC, Tabei SM, Kirov SM, Shaw JG.

Infect Immun. 2012 Apr;80(4):1351-60. doi: 10.1128/IAI.06304-11. Epub 2012 Feb 6.

22.

Capillary blood flow around microglial somata determines dynamics of microglial processes in ischemic conditions.

Masuda T, Croom D, Hida H, Kirov SA.

Glia. 2011 Nov;59(11):1744-53. doi: 10.1002/glia.21220. Epub 2011 Jul 28.

23.

Dibucaine mitigates spreading depolarization in human neocortical slices and prevents acute dendritic injury in the ischemic rodent neocortex.

Risher WC, Lee MR, Fomitcheva IV, Hess DC, Kirov SA.

PLoS One. 2011;6(7):e22351. doi: 10.1371/journal.pone.0022351. Epub 2011 Jul 15.

24.

Specific regulation of NRG1 isoform expression by neuronal activity.

Liu X, Bates R, Yin DM, Shen C, Wang F, Su N, Kirov SA, Luo Y, Wang JZ, Xiong WC, Mei L.

J Neurosci. 2011 Jun 8;31(23):8491-501. doi: 10.1523/JNEUROSCI.5317-10.2011.

25.

Potent inhibition of anoxic depolarization by the sodium channel blocker dibucaine.

Douglas HA, Callaway JK, Sword J, Kirov SA, Andrew RD.

J Neurophysiol. 2011 Apr;105(4):1482-94. doi: 10.1152/jn.00817.2010. Epub 2011 Jan 27.

26.

Fear and shame: using theatre to destigmatise mental illness in an Australian Macedonian community.

Blignault I, Smith S, Woodland L, Ponzio V, Ristevski D, Kirov S.

Health Promot J Austr. 2010 Aug;21(2):120-6. Erratum in: Health Promot J Austr. 2010 Dec;21(3):244.

PMID:
20701561
27.

Peri-hemorrhagic degeneration accompanies stereotaxic collagenase-mediated cortical hemorrhage in mouse.

Masuda T, Maki M, Hara K, Yasuhara T, Matsukawa N, Yu S, Bae EC, Tajiri N, Chheda SH, Solomita MA, Weinbren N, Kaneko Y, Kirov SA, Hess DC, Hida H, Borlongan CV.

Brain Res. 2010 Oct 8;1355:228-39. doi: 10.1016/j.brainres.2010.07.101. Epub 2010 Aug 5.

PMID:
20691669
28.

Recurrent spontaneous spreading depolarizations facilitate acute dendritic injury in the ischemic penumbra.

Risher WC, Ard D, Yuan J, Kirov SA.

J Neurosci. 2010 Jul 21;30(29):9859-68. doi: 10.1523/JNEUROSCI.1917-10.2010.

29.

Using a multifaceted community intervention to reduce stigma about mental illness in an Australian Macedonian community.

Blignault I, Woodland L, Ponzio V, Ristevski D, Kirov S.

Health Promot J Austr. 2009 Dec;20(3):227-33.

PMID:
19951244
30.

Three-dimensional relationships between perisynaptic astroglia and human hippocampal synapses.

Witcher MR, Park YD, Lee MR, Sharma S, Harris KM, Kirov SA.

Glia. 2010 Apr;58(5):572-87. doi: 10.1002/glia.20946.

31.

Iron-binding compounds impair Pseudomonas aeruginosa biofilm formation, especially under anaerobic conditions.

O'May CY, Sanderson K, Roddam LF, Kirov SM, Reid DW.

J Med Microbiol. 2009 Jun;58(Pt 6):765-73. doi: 10.1099/jmm.0.004416-0.

PMID:
19429753
32.

Iron chelation directed against biofilms as an adjunct to conventional antibiotics.

Reid DW, O'May C, Kirov SM, Roddam L, Lamont IL, Sanderson K.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L857-8. doi: 10.1152/ajplung.00058.2009. No abstract available.

33.

The PAZAR database of gene regulatory information coupled to the ORCA toolkit for the study of regulatory sequences.

Portales-Casamar E, Arenillas D, Lim J, Swanson MI, Jiang S, McCallum A, Kirov S, Wasserman WW.

Nucleic Acids Res. 2009 Jan;37(Database issue):D54-60. doi: 10.1093/nar/gkn783. Epub 2008 Oct 29.

34.
35.

Bacterial cyanogenesis occurs in the cystic fibrosis lung.

Sanderson K, Wescombe L, Kirov SM, Champion A, Reid DW.

Eur Respir J. 2008 Aug;32(2):329-33. doi: 10.1183/09031936.00152407. Epub 2008 May 14.

36.

Association analysis for large-scale gene set data.

Kirov SA, Zhang B, Snoddy JR.

Methods Mol Biol. 2007;408:19-33. doi: 10.1007/978-1-59745-547-3_2.

PMID:
18314575
37.

PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation.

Portales-Casamar E, Kirov S, Lim J, Lithwick S, Swanson MI, Ticoll A, Snoddy J, Wasserman WW.

Genome Biol. 2007;8(10):R207.

38.

Biofilm differentiation and dispersal in mucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.

Kirov SM, Webb JS, O'may CY, Reid DW, Woo JK, Rice SA, Kjelleberg S.

Microbiology. 2007 Oct;153(Pt 10):3264-74.

PMID:
17906126
39.

Whole isolated neocortical and hippocampal preparations and their use in imaging studies.

Davies ML, Kirov SA, Andrew RD.

J Neurosci Methods. 2007 Nov 30;166(2):203-16. Epub 2007 Jul 25.

40.

Increased airway iron as a potential factor in the persistence of Pseudomonas aeruginosa infection in cystic fibrosis.

Reid DW, Carroll V, O'May C, Champion A, Kirov SM.

Eur Respir J. 2007 Aug;30(2):286-92. Epub 2007 May 15.

41.

Biofilm dispersal and exacerbations of cystic fibrosis lung disease.

Reid DW, Kirov SM, Webb JS, Carroll V, Kjelleberg S, Champion A, Sanderson K.

Pediatr Pulmonol. 2006 Dec;41(12):1254; author reply 1255. No abstract available.

PMID:
17068827
42.

Anaerobic culture conditions favor biofilm-like phenotypes in Pseudomonas aeruginosa isolates from patients with cystic fibrosis.

O'May CY, Reid DW, Kirov SM.

FEMS Immunol Med Microbiol. 2006 Dec;48(3):373-80. Epub 2006 Oct 18.

43.

Plasticity of perisynaptic astroglia during synaptogenesis in the mature rat hippocampus.

Witcher MR, Kirov SA, Harris KM.

Glia. 2007 Jan 1;55(1):13-23.

PMID:
17001633
44.

Warmer preparation of hippocampal slices prevents synapse proliferation that might obscure LTP-related structural plasticity.

Bourne JN, Kirov SA, Sorra KE, Harris KM.

Neuropharmacology. 2007 Jan;52(1):55-9. Epub 2006 Aug 8.

PMID:
16895730
45.

Dense core vesicles resemble active-zone transport vesicles and are diminished following synaptogenesis in mature hippocampal slices.

Sorra KE, Mishra A, Kirov SA, Harris KM.

Neuroscience. 2006 Sep 15;141(4):2097-106. Epub 2006 Jun 22.

PMID:
16797135
46.

Physiological evidence that pyramidal neurons lack functional water channels.

Andrew RD, Labron MW, Boehnke SE, Carnduff L, Kirov SA.

Cereb Cortex. 2007 Apr;17(4):787-802. Epub 2006 May 24.

PMID:
16723408
47.

Clinical significance of seeding dispersal in biofilms.

Kirov SM, Webb JS, Kjelleberg S.

Microbiology. 2005 Nov;151(Pt 11):3452-3; discussion 3453. No abstract available.

PMID:
16272368
48.

Computational, integrative, and comparative methods for the elucidation of genetic coexpression networks.

Baldwin NE, Chesler EJ, Kirov S, Langston MA, Snoddy JR, Williams RW, Zhang B.

J Biomed Biotechnol. 2005 Jun 30;2005(2):172-80.

49.

Gene expression profiling in the hippocampus of learned helpless and nonhelpless rats.

Kohen R, Kirov S, Navaja GP, Happe HK, Hamblin MW, Snoddy JR, Neumaier JF, Petty F.

Pharmacogenomics J. 2005;5(5):278-91.

PMID:
16010284
50.

WebGestalt: an integrated system for exploring gene sets in various biological contexts.

Zhang B, Kirov S, Snoddy J.

Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W741-8.

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