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Items: 15


Bioengineered human acellular vessels recellularize and evolve into living blood vessels after human implantation.

Kirkton RD, Santiago-Maysonet M, Lawson JH, Tente WE, Dahl SLM, Niklason LE, Prichard HL.

Sci Transl Med. 2019 Mar 27;11(485). pii: eaau6934. doi: 10.1126/scitranslmed.aau6934.


Generation and customization of biosynthetic excitable tissues for electrophysiological studies and cell-based therapies.

Nguyen HX, Kirkton RD, Bursac N.

Nat Protoc. 2018 May;13(5):927-945. doi: 10.1038/nprot.2018.016. Epub 2018 Apr 5.


Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection.

Kirkton RD, Prichard HL, Santiago-Maysonet M, Niklason LE, Lawson JH, Dahl SLM.

J Surg Res. 2018 Jan;221:143-151. doi: 10.1016/j.jss.2017.08.035. Epub 2017 Sep 19.


Modeling an Excitable Biosynthetic Tissue with Inherent Variability for Paired Computational-Experimental Studies.

Gokhale TA, Kim JM, Kirkton RD, Bursac N, Henriquez CS.

PLoS Comput Biol. 2017 Jan 20;13(1):e1005342. doi: 10.1371/journal.pcbi.1005342. eCollection 2017 Jan.


Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage.

Christoforou N, Chakraborty S, Kirkton RD, Adler AF, Addis RC, Leong KW.

Sci Rep. 2017 Jan 10;7:40285. doi: 10.1038/srep40285.


Engineering prokaryotic channels for control of mammalian tissue excitability.

Nguyen HX, Kirkton RD, Bursac N.

Nat Commun. 2016 Oct 18;7:13132. doi: 10.1038/ncomms13132.


Spatial profiles of electrical mismatch determine vulnerability to conduction failure across a host-donor cell interface.

Kirkton RD, Badie N, Bursac N.

Circ Arrhythm Electrophysiol. 2013 Dec;6(6):1200-7. doi: 10.1161/CIRCEP.113.001050. Epub 2013 Nov 14.


Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming.

Christoforou N, Chellappan M, Adler AF, Kirkton RD, Wu T, Addis RC, Bursac N, Leong KW.

PLoS One. 2013 May 21;8(5):e63577. doi: 10.1371/journal.pone.0063577. Print 2013.


Genetic engineering of somatic cells to study and improve cardiac function.

Kirkton RD, Bursac N.

Europace. 2012 Nov;14 Suppl 5:v40-v49. doi: 10.1093/europace/eus269.


Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts.

Wang C, Hennessey JA, Kirkton RD, Wang C, Graham V, Puranam RS, Rosenberg PB, Bursac N, Pitt GS.

Circ Res. 2011 Sep 16;109(7):775-82. doi: 10.1161/CIRCRESAHA.111.247957. Epub 2011 Aug 4.


Characterizing functional stem cell-cardiomyocyte interactions.

Bursac N, Kirkton RD, McSpadden LC, Liau B.

Regen Med. 2010 Jan;5(1):87-105. doi: 10.2217/rme.09.69. Review.


Electrotonic loading of anisotropic cardiac monolayers by unexcitable cells depends on connexin type and expression level.

McSpadden LC, Kirkton RD, Bursac N.

Am J Physiol Cell Physiol. 2009 Aug;297(2):C339-51. doi: 10.1152/ajpcell.00024.2009. Epub 2009 Jun 3.


Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes.

Pedrotty DM, Klinger RY, Kirkton RD, Bursac N.

Cardiovasc Res. 2009 Sep 1;83(4):688-97. doi: 10.1093/cvr/cvp164. Epub 2009 May 28.


Genetic engineering and stem cells: combinatorial approaches for cardiac cell therapy.

Kirkton RD, Bursac N.

IEEE Eng Med Biol Mag. 2008 May-Jun;27(3):85-8. doi: 10.1109/MEMB.2008.922356. No abstract available.

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