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Items: 1 to 50 of 78

1.

Moving galectin-3 closer to the goal line.

Kirk JA, de Boer RA.

Am J Physiol Heart Circ Physiol. 2019 Mar 1;316(3):H580-H582. doi: 10.1152/ajpheart.00761.2018. Epub 2018 Dec 21. No abstract available.

PMID:
30575435
2.

Estrogen but not testosterone preserves myofilament function from doxorubicin-induced cardiotoxicity by reducing oxidative modifications.

Rattanasopa C, Kirk JA, Bupha-Intr T, Papadaki M, de Tombe PP, Wattanapermpool J.

Am J Physiol Heart Circ Physiol. 2019 Feb 1;316(2):H360-H370. doi: 10.1152/ajpheart.00428.2018. Epub 2018 Nov 30.

PMID:
30499711
3.

Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function.

Papadaki M, Holewinski RJ, Previs SB, Martin TG, Stachowski MJ, Li A, Blair CA, Moravec CS, Van Eyk JE, Campbell KS, Warshaw DM, Kirk JA.

JCI Insight. 2018 Oct 18;3(20). pii: 121264. doi: 10.1172/jci.insight.121264.

4.

Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy.

Stachowski MJ, Holewinski RJ, Grote E, Venkatraman V, Van Eyk JE, Kirk JA.

Proteomics. 2018 Oct;18(19):e1800079. doi: 10.1002/pmic.201800079. Epub 2018 Aug 30.

5.

Galectin-3 in the pathogenesis of heart failure: a causative mediator or simply a biomarker?

Kirk JA, Frangogiannis NG.

Am J Physiol Heart Circ Physiol. 2018 Jun 1;314(6):H1256-H1258. doi: 10.1152/ajpheart.00150.2018. Epub 2018 Mar 2. No abstract available.

6.

Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis-Associated Versus Idiopathic Pulmonary Arterial Hypertension.

Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA.

Circulation. 2018 May 29;137(22):2360-2370. doi: 10.1161/CIRCULATIONAHA.117.033147. Epub 2018 Jan 19.

7.

The role of heat shock proteins and co-chaperones in heart failure.

Ranek MJ, Stachowski MJ, Kirk JA, Willis MS.

Philos Trans R Soc Lond B Biol Sci. 2018 Jan 19;373(1738). pii: 20160530. doi: 10.1098/rstb.2016.0530. Review.

8.

New class of precision antimicrobials redefines role of Clostridium difficile S-layer in virulence and viability.

Kirk JA, Gebhart D, Buckley AM, Lok S, Scholl D, Douce GR, Govoni GR, Fagan RP.

Sci Transl Med. 2017 Sep 6;9(406). pii: eaah6813. doi: 10.1126/scitranslmed.aah6813.

9.

Family history of cancer predicts endometrial cancer risk independently of Lynch Syndrome: Implications for genetic counselling.

Johnatty SE, Tan YY, Buchanan DD, Bowman M, Walters RJ, Obermair A, Quinn MA, Blomfield PB, Brand A, Leung Y, Oehler MK; ANECS Group, Kirk JA, O'Mara TA, Webb PM, Spurdle AB.

Gynecol Oncol. 2017 Nov;147(2):381-387. doi: 10.1016/j.ygyno.2017.08.011. Epub 2017 Aug 17.

PMID:
28822557
10.

Ventricular-arterial coupling in centenarians without cardiovascular diseases.

Sonaglioni A, Baravelli M, Lombardo M, Sommese C, Anzà C, Kirk JA, Padeletti L.

Aging Clin Exp Res. 2018 Apr;30(4):367-373. doi: 10.1007/s40520-017-0783-y. Epub 2017 Jun 14.

PMID:
28616854
11.

Cellular and Molecular Aspects of Dyssynchrony and Resynchronization.

Kirk JA, Kass DA.

Heart Fail Clin. 2017 Jan;13(1):29-41. doi: 10.1016/j.hfc.2016.07.003. Review.

PMID:
27886930
12.

Heat shock increases conjugation efficiency in Clostridium difficile.

Kirk JA, Fagan RP.

Anaerobe. 2016 Dec;42:1-5. doi: 10.1016/j.anaerobe.2016.06.009. Epub 2016 Jul 1.

13.

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.

Ngkelo A, Richart A, Kirk JA, Bonnin P, Vilar J, Lemitre M, Marck P, Branchereau M, Le Gall S, Renault N, Guerin C, Ranek MJ, Kervadec A, Danelli L, Gautier G, Blank U, Launay P, Camerer E, Bruneval P, Menasche P, Heymes C, Luche E, Casteilla L, Cousin B, Rodewald HR, Kass DA, Silvestre JS.

J Exp Med. 2016 Jun 27;213(7):1353-74. doi: 10.1084/jem.20160081.

14.

Characteristics of the Clostridium difficile cell envelope and its importance in therapeutics.

Kirk JA, Banerji O, Fagan RP.

Microb Biotechnol. 2017 Jan;10(1):76-90. doi: 10.1111/1751-7915.12372. Epub 2016 Jun 17. Review.

15.

Pacemaker-induced transient asynchrony suppresses heart failure progression.

Kirk JA, Chakir K, Lee KH, Karst E, Holewinski RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA.

Sci Transl Med. 2015 Dec 23;7(319):319ra207. doi: 10.1126/scitranslmed.aad2899.

16.

Thrombospondins in the transition from myocardial infarction to heart failure.

Kirk JA, Cingolani OH.

J Mol Cell Cardiol. 2016 Jan;90:102-10. doi: 10.1016/j.yjmcc.2015.12.009. Epub 2015 Dec 10. Review.

17.

Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials.

Kirk JA, Holewinski RJ, Crowgey EL, Van Eyk JE.

Proteomics. 2016 Mar;16(5):894-905. doi: 10.1002/pmic.201500401. Epub 2016 Feb 16. Review.

PMID:
26670943
18.

Cellular and Molecular Aspects of Dyssynchrony and Resynchronization.

Kirk JA, Kass DA.

Card Electrophysiol Clin. 2015 Dec;7(4):585-97. doi: 10.1016/j.ccep.2015.08.011. Review.

19.

Citrullination of myofilament proteins in heart failure.

Fert-Bober J, Giles JT, Holewinski RJ, Kirk JA, Uhrigshardt H, Crowgey EL, Andrade F, Bingham CO 3rd, Park JK, Halushka MK, Kass DA, Bathon JM, Van Eyk JE.

Cardiovasc Res. 2015 Nov 1;108(2):232-42. doi: 10.1093/cvr/cvv185. Epub 2015 Jun 25.

20.

Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.

Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, Margulies KB, Van Eyk JE, Paulus WJ, Takimoto E, Kass DA.

Nature. 2015 Mar 26;519(7544):472-6. doi: 10.1038/nature14332. Epub 2015 Mar 18.

21.

New redox-related arrows in the arsenal of cardiac disease treatment.

Kirk JA, Paolocci N.

Antioxid Redox Signal. 2014 Nov 10;21(14):1945-8. doi: 10.1089/ars.2014.6124. Epub 2014 Oct 2.

PMID:
25211226
22.

Identification of cardiac myofilament protein isoforms using multiple mass spectrometry based approaches.

Kooij V, Venkatraman V, Kirk JA, Ubaida-Mohien C, Graham DR, Faber MJ, Van Eyk JE.

Proteomics Clin Appl. 2014 Aug;8(7-8):578-589. doi: 10.1002/prca.201400039.

23.

Reply to J. Moline et al.

Buchanan DD, Tan YY, Walsh MD, Clendenning M, Metcalf AM, Ferguson K, Arnold ST, Thompson BA, Lose FA, Parsons MT, Walters RJ, Pearson SA, Cummings M, Oehler MK, Blomfield PB, Quinn MA, Kirk JA, Stewart CJ, Obermair A, Young JP, Webb PM, Spurdle AB.

J Clin Oncol. 2014 Jul 20;32(21):2278-9. doi: 10.1200/JCO.2014.55.8213. Epub 2014 Jun 9. No abstract available.

PMID:
24912891
24.

Sizing up models of heart failure: Proteomics from flies to humans.

Kooij V, Venkatraman V, Tra J, Kirk JA, Rowell J, Blice-Baum A, Cammarato A, Van Eyk JE.

Proteomics Clin Appl. 2014 Oct;8(9-10):653-64. doi: 10.1002/prca.201300123. Epub 2014 Jun 25. Review.

25.

Desmin modifications associate with amyloid-like oligomers deposition in heart failure.

Agnetti G, Halperin VL, Kirk JA, Chakir K, Guo Y, Lund L, Nicolini F, Gherli T, Guarnieri C, Caldarera CM, Tomaselli GF, Kass DA, Van Eyk JE.

Cardiovasc Res. 2014 Apr 1;102(1):24-34. doi: 10.1093/cvr/cvu003. Epub 2014 Jan 9.

26.

Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing.

Buchanan DD, Tan YY, Walsh MD, Clendenning M, Metcalf AM, Ferguson K, Arnold ST, Thompson BA, Lose FA, Parsons MT, Walters RJ, Pearson SA, Cummings M, Oehler MK, Blomfield PB, Quinn MA, Kirk JA, Stewart CJ, Obermair A, Young JP, Webb PM, Spurdle AB.

J Clin Oncol. 2014 Jan 10;32(2):90-100. doi: 10.1200/JCO.2013.51.2129. Epub 2013 Dec 9.

27.

Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β.

Kirk JA, Holewinski RJ, Kooij V, Agnetti G, Tunin RS, Witayavanitkul N, de Tombe PP, Gao WD, Van Eyk J, Kass DA.

J Clin Invest. 2014 Jan;124(1):129-38.

28.

A Priori Identifiability Analysis of Cardiovascular Models.

Kirk JA, Saccomani MP, Shroff SG.

Cardiovasc Eng Technol. 2013 Dec;4(4):500-512.

29.

Electromechanical dyssynchrony and resynchronization of the failing heart.

Kirk JA, Kass DA.

Circ Res. 2013 Aug 30;113(6):765-76. doi: 10.1161/CIRCRESAHA.113.300270. Review.

30.

Troponin I alterations detected by multiple-reaction monitoring: how might this impact the study of heart failure?

Kirk JA, Zhang P, Murphy AM, Van Eyk JE.

Expert Rev Proteomics. 2013 Feb;10(1):5-8. doi: 10.1586/epr.12.77. No abstract available.

PMID:
23414352
31.

Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart.

Zhang P, Kirk JA, Ji W, dos Remedios CG, Kass DA, Van Eyk JE, Murphy AM.

Circulation. 2012 Oct 9;126(15):1828-37. doi: 10.1161/CIRCULATIONAHA.112.096388. Epub 2012 Sep 12.

32.

Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes.

Rainer PP, Doleschal B, Kirk JA, Sivakumaran V, Saad Z, Groschner K, Maechler H, Hoefler G, Bauernhofer T, Samonigg H, Hutterer G, Kass DA, Pieske B, von Lewinski D, Pichler M.

BJU Int. 2012 Nov;110(10):1455-62. doi: 10.1111/j.1464-410X.2012.11134.x. Epub 2012 Apr 17.

33.

Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved.

Gupta A, Akki A, Wang Y, Leppo MK, Chacko VP, Foster DB, Caceres V, Shi S, Kirk JA, Su J, Lai S, Paolocci N, Steenbergen C, Gerstenblith G, Weiss RG.

J Clin Invest. 2012 Jan;122(1):291-302. doi: 10.1172/JCI57426. Epub 2011 Dec 27.

34.

Thrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle.

Cingolani OH, Kirk JA, Seo K, Koitabashi N, Lee DI, Ramirez-Correa G, Bedja D, Barth AS, Moens AL, Kass DA.

Circ Res. 2011 Dec 9;109(12):1410-4. doi: 10.1161/CIRCRESAHA.111.256743. Epub 2011 Oct 27.

35.

Are videoconferenced consultations as effective as face-to-face consultations for hereditary breast and ovarian cancer genetic counseling?

Zilliacus EM, Meiser B, Lobb EA, Kelly PJ, Barlow-Stewart K, Kirk JA, Spigelman AD, Warwick LJ, Tucker KM.

Genet Med. 2011 Nov;13(11):933-41. doi: 10.1097/GIM.0b013e3182217a19.

PMID:
21799430
36.

Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I.

Kirk JA, MacGowan GA, Evans C, Smith SH, Warren CM, Mamidi R, Chandra M, Stewart AF, Solaro RJ, Shroff SG.

Circ Res. 2009 Dec 4;105(12):1232-9. doi: 10.1161/CIRCRESAHA.109.205427. Epub 2009 Oct 22.

37.

A three-dimensional gel bioreactor for assessment of cardiomyocyte induction in skeletal muscle-derived stem cells.

Clause KC, Tinney JP, Liu LJ, Gharaibeh B, Huard J, Kirk JA, Shroff SG, Fujimoto KL, Wagner WR, Ralphe JC, Keller BB, Tobita K.

Tissue Eng Part C Methods. 2010 Jun;16(3):375-85. doi: 10.1089/ten.TEC.2009.0098.

38.

Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6J mice.

Naghshin J, McGaffin KR, Witham WG, Mathier MA, Romano LC, Smith SH, Janczewski AM, Kirk JA, Shroff SG, O'Donnell CP.

J Appl Physiol (1985). 2009 Sep;107(3):787-93. doi: 10.1152/japplphysiol.91256.2008. Epub 2009 Jul 9.

39.

Histopathological features of breast cancer in carriers of ATM gene variants.

Balleine RL, Murali R, Bilous AM, Farshid G, Waring P, Provan P, Byth K, Thorne H; kConFab Investigators, Kirk JA.

Histopathology. 2006 Nov;49(5):523-32.

PMID:
17064299
40.

Screening behavior in women at increased familial risk for breast cancer.

Antill YC, Reynolds J, Young MA, Kirk JA, Tucker KM, Bogtstra TL, Wong SS, Dudding TE, Di Iulio JL, Phillips KA.

Fam Cancer. 2006;5(4):359-68. Epub 2006 Jul 7.

PMID:
16817030
41.

How can we best detect hereditary non-polyposis colorectal cancer?

Kirk JA.

Med J Aust. 2006 Mar 6;184(5):206-7.

PMID:
16515428
42.

Pressure-calcium relationships in perfused mouse hearts.

MacGowan GA, Kirk JA, Evans C, Shroff SG.

Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2614-24. Epub 2006 Jan 13.

43.

Absence of a weight gain response to Vitamin B12 supplementation in weaned dairy heifers grazing pastures of marginal cobalt content.

Clark RG, Ellison RS, Mortleman L, Kirk JA, Henderson HV.

N Z Vet J. 1999 Aug;47(4):125-7. Erratum in: N Z Vet J. 2000 Jun;48(3):90.

PMID:
16032088
44.

Large genomic rearrangements of both BRCA2 and BRCA1 are a feature of the inherited breast/ovarian cancer phenotype in selected families.

Woodward AM, Davis TA, Silva AG, Kirk JA, Leary JA; kConFab Investigators.

J Med Genet. 2005 May;42(5):e31.

45.

Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A.

Mote PA, Leary JA, Avery KA, Sandelin K, Chenevix-Trench G, Kirk JA, Clarke CL; kConFab Investigators.

Genes Chromosomes Cancer. 2004 Mar;39(3):236-48.

PMID:
14732925
46.

Unmasking the S-phase-promoting potential of cyclin B1.

Moore JD, Kirk JA, Hunt T.

Science. 2003 May 9;300(5621):987-90.

47.

kConFab: a research resource of Australasian breast cancer families. Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer.

Osborne RH, Hopper JL, Kirk JA, Chenevix-Trench G, Thorne HJ, Sambrook JF.

Med J Aust. 2000 May 1;172(9):463-4. No abstract available.

PMID:
10870547
48.

Loss of nuclear BRCA1 expression in breast cancers is associated with a highly proliferative tumor phenotype.

Jarvis EM, Kirk JA, Clarke CL.

Cancer Genet Cytogenet. 1998 Mar;101(2):109-15.

PMID:
9494611
49.

Pediatric trauma.

Kirk JA.

CRNA. 1997 Nov;8(4):135-43. Review.

PMID:
9437948
50.

Association of hereditary angioedema and hereditary breast cancer.

Christie DR, Kirk JA, Clarke CL, Boyages J.

Cancer Genet Cytogenet. 1997 Jun;95(2):159-62.

PMID:
9169034

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