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Items: 1 to 50 of 82

1.

Photo-Induced Doping in a Graphene Field-Effect Transistor with Inkjet-Printed Organic Semiconducting Molecules.

Nekrasov N, Kireev D, Omerović N, Emelianov A, Bobrinetskiy I.

Nanomaterials (Basel). 2019 Dec 10;9(12). pii: E1753. doi: 10.3390/nano9121753.

2.

Wearable graphene sensors use ambient light to monitor health.

Akinwande D, Kireev D.

Nature. 2019 Dec;576(7786):220-221. doi: 10.1038/d41586-019-03483-7. No abstract available.

PMID:
31822826
3.

Off-Pocket Activity Cliffs: A Puzzling Facet of Molecular Recognition.

Abramyan TM, An Y, Kireev D.

J Chem Inf Model. 2019 Dec 16. doi: 10.1021/acs.jcim.9b00731. [Epub ahead of print]

PMID:
31790251
4.

MEA Recordings and Cell-Substrate Investigations with Plasmonic and Transparent, Tunable Holey Gold.

Hondrich TJJ, Lenyk B, Shokoohimehr P, Kireev D, Maybeck V, Mayer D, Offenhäusser A.

ACS Appl Mater Interfaces. 2019 Dec 18;11(50):46451-46461. doi: 10.1021/acsami.9b14948. Epub 2019 Dec 6.

PMID:
31752486
5.

RT-qPCR Detection of Low-Copy HIV RNA with Yin-Yang Probes.

Kireev DE, Farzan VM, Shipulin GA, Korshun VA, Zatsepin TS.

Methods Mol Biol. 2020;2063:27-35. doi: 10.1007/978-1-0716-0138-9_3.

PMID:
31667760
6.

Ultrasensitive Field-Effect Biosensors Enabled by the Unique Electronic Properties of Graphene.

Zhang X, Jing Q, Ao S, Schneider GF, Kireev D, Zhang Z, Fu W.

Small. 2019 Oct 8:e1902820. doi: 10.1002/smll.201902820. [Epub ahead of print] Review.

PMID:
31592577
7.

Graphene-Based Sensing Platform for On-Chip Ochratoxin A Detection.

Nekrasov N, Kireev D, Emelianov A, Bobrinetskiy I.

Toxins (Basel). 2019 Sep 20;11(10). pii: E550. doi: 10.3390/toxins11100550.

8.

Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology.

Da C, Zhang D, Stashko M, Vasileiadi E, Parker RE, Minson KA, Huey MG, Huelse JM, Hunter D, Gilbert TSK, Norris-Drouin J, Miley M, Herring LE, Graves LM, DeRyckere D, Earp HS, Graham DK, Frye SV, Wang X, Kireev D.

J Am Chem Soc. 2019 Oct 2;141(39):15700-15709. doi: 10.1021/jacs.9b08660. Epub 2019 Sep 20.

PMID:
31497954
9.

Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7.

Lamb KN, Bsteh D, Dishman SN, Moussa HF, Fan H, Stuckey JI, Norris JL, Cholensky SH, Li D, Wang J, Sagum C, Stanton BZ, Bedford MT, Pearce KH, Kenakin TP, Kireev DB, Wang GG, James LI, Bell O, Frye SV.

Cell Chem Biol. 2019 Oct 17;26(10):1365-1379.e22. doi: 10.1016/j.chembiol.2019.07.013. Epub 2019 Aug 15.

PMID:
31422906
10.

N3-MEA Probes: Scooping Neuronal Networks.

Kireev D, Rincón Montes V, Stevanovic J, Srikantharajah K, Offenhäusser A.

Front Neurosci. 2019 Apr 10;13:320. doi: 10.3389/fnins.2019.00320. eCollection 2019.

11.

Discovery of selective activators of PRC2 mutant EED-I363M.

Suh JL, Barnash KD, Abramyan TM, Li F, The J, Engelberg IA, Vedadi M, Brown PJ, Kireev DB, Arrowsmith CH, James LI, Frye SV.

Sci Rep. 2019 Apr 25;9(1):6524. doi: 10.1038/s41598-019-43005-z.

12.

Molecular Epidemiology of HIV-1 Subtype G in the Russian Federation.

Murzakova A, Kireev D, Baryshev P, Lopatukhin A, Serova E, Shemshura A, Saukhat S, Kolpakov D, Matuzkova A, Suladze A, Nosik M, Eremin V, Shipulin G, Pokrovsky V.

Viruses. 2019 Apr 16;11(4). pii: E348. doi: 10.3390/v11040348.

13.

Dynamics of Substrate Processing by PPIP5K2, a Versatile Catalytic Machine.

An Y, Jessen HJ, Wang H, Shears SB, Kireev D.

Structure. 2019 Jun 4;27(6):1022-1028.e2. doi: 10.1016/j.str.2019.03.007. Epub 2019 Apr 4.

PMID:
30956131
14.

A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes.

Yuen LH, Dana S, Liu Y, Bloom SI, Thorsell AG, Neri D, Donato AJ, Kireev D, Schüler H, Franzini RM.

J Am Chem Soc. 2019 Apr 3;141(13):5169-5181. doi: 10.1021/jacs.8b08039. Epub 2019 Mar 19.

PMID:
30855951
15.

Novel homo Yin-Yang probes improve sensitivity in RT-qPCR detection of low copy HIV RNA.

Farzan VM, Kvach MV, Aparin IO, Kireev DE, Prikazchikova TA, Ustinov AV, Shmanai VV, Shipulin GA, Korshun VA, Zatsepin TS.

Talanta. 2019 Mar 1;194:226-232. doi: 10.1016/j.talanta.2018.10.043. Epub 2018 Oct 16.

PMID:
30609524
16.

Correction to "Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID subunit 1".

Suh JL, Watts B, Stuckey JI, Norris-Drouin JL, Cholensky SH, Dickson BM, An Y, Mathea S, Salah E, Knapp S, Khan A, Adams AT, Strahl BD, Sagum CA, Bedford MT, James LI, Kireev DB, Frye SV.

Biochemistry. 2018 Dec 11;57(49):6806. doi: 10.1021/acs.biochem.8b01187. Epub 2018 Nov 28. No abstract available.

PMID:
30485080
17.

Highly Selective MERTK Inhibitors Achieved by a Single Methyl Group.

Zhao J, Zhang D, Zhang W, Stashko MA, DeRyckere D, Vasileiadi E, Parker RE, Hunter D, Liu Q, Zhang Y, Norris-Drouin J, Li B, Drewry DH, Kireev D, Graham DK, Earp HS, Frye SV, Wang X.

J Med Chem. 2018 Nov 21;61(22):10242-10254. doi: 10.1021/acs.jmedchem.8b01229. Epub 2018 Nov 5.

PMID:
30347155
18.

High Performance Flexible Organic Electrochemical Transistors for Monitoring Cardiac Action Potential.

Liang Y, Ernst M, Brings F, Kireev D, Maybeck V, Offenhäusser A, Mayer D.

Adv Healthc Mater. 2018 Oct;7(19):e1800304. doi: 10.1002/adhm.201800304. Epub 2018 Aug 14.

PMID:
30109770
19.

Evaluating the accuracy and sensitivity of detecting minority HIV-1 populations by Illumina next-generation sequencing.

Kireev DE, Lopatukhin AE, Murzakova AV, Pimkina EV, Speranskaya AS, Neverov AD, Fedonin GG, Fantin YS, Shipulin GA.

J Virol Methods. 2018 Nov;261:40-45. doi: 10.1016/j.jviromet.2018.08.001. Epub 2018 Aug 4.

PMID:
30086382
20.

Identification of Cosalane as an Inhibitor of Human and Murine CC-Chemokine Receptor 7 Signaling via a High-Throughput Screen.

Hull-Ryde EA, Porter MA, Fowler KA, Kireev D, Li K, Simpson CD, Sassano MF, Suto MJ, Pearce KH, Janzen W, Coghill JM.

SLAS Discov. 2018 Dec;23(10):1083-1091. doi: 10.1177/2472555218780917. Epub 2018 Jun 29.

PMID:
29958052
21.

Use of Protein Kinase-Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors.

Puhl-Rubio AC, Stashko MA, Wang H, Hardy PB, Tyagi V, Li B, Wang X, Kireev D, Jessen HJ, Frye SV, Shears SB, Pearce KH.

SLAS Discov. 2018 Oct;23(9):982-988. doi: 10.1177/2472555218775323. Epub 2018 May 29.

22.

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth.

Krulikas LJ, McDonald IM, Lee B, Okumu DO, East MP, Gilbert TSK, Herring LE, Golitz BT, Wells CI, Axtman AD, Zuercher WJ, Willson TM, Kireev D, Yeh JJ, Johnson GL, Baines AT, Graves LM.

SLAS Discov. 2018 Sep;23(8):850-861. doi: 10.1177/2472555218773045. Epub 2018 May 9.

23.

Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1.

Suh JL, Watts B, Stuckey JI, Norris-Drouin JL, Cholensky SH, Dickson BM, An Y, Mathea S, Salah E, Knapp S, Khan A, Adams AT, Strahl BD, Sagum CA, Bedford MT, James LI, Kireev DB, Frye SV.

Biochemistry. 2018 Apr 10;57(14):2140-2149. doi: 10.1021/acs.biochem.8b00150. Epub 2018 Mar 28. Erratum in: Biochemistry. 2018 Dec 11;57(49):6806.

24.

[Molecular epidemiological analysis of HIV-1 variants circulating in Russia in 1987-2015].

Lapovok IA, Lopatukhin AE, Kireev DE, Kazennova EV, Lebedev AV, Bobkova MR, Kolomeets AN, Turbina GI, Shipulin GA, Ladnaya NN, Pokrovsky VV.

Ter Arkh. 2017;89(11):44-49. doi: 10.17116/terarkh2017891144-49. Russian.

PMID:
29260745
25.

Biosensing near the neutrality point of graphene.

Fu W, Feng L, Panaitov G, Kireev D, Mayer D, Offenhäusser A, Krause HJ.

Sci Adv. 2017 Oct 25;3(10):e1701247. doi: 10.1126/sciadv.1701247. eCollection 2017 Oct.

26.

Graphene transistors for interfacing with cells: towards a deeper understanding of liquid gating and sensitivity.

Kireev D, Brambach M, Seyock S, Maybeck V, Fu W, Wolfrum B, Offenhäusser A.

Sci Rep. 2017 Jul 27;7(1):6658. doi: 10.1038/s41598-017-06906-5.

27.

Retraction: A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors.

Baughman BM, Wang H, An Y, Kireev D, Stashko MA, Jessen HJ, Pearce KH, Frye SV, Shears SB.

PLoS One. 2017 Jun 21;12(6):e0180272. doi: 10.1371/journal.pone.0180272. eCollection 2017. No abstract available.

28.

Graphene Multielectrode Arrays as a Versatile Tool for Extracellular Measurements.

Kireev D, Seyock S, Lewen J, Maybeck V, Wolfrum B, Offenhäusser A.

Adv Healthc Mater. 2017 Jun;6(12). doi: 10.1002/adhm.201601433. Epub 2017 Apr 3.

PMID:
28371490
29.

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

McIver AL, Zhang W, Liu Q, Jiang X, Stashko MA, Nichols J, Miley MJ, Norris-Drouin J, Machius M, DeRyckere D, Wood E, Graham DK, Earp HS, Kireev D, Frye SV, Wang X.

ChemMedChem. 2017 Feb 3;12(3):207-213. doi: 10.1002/cmdc.201600589. Epub 2017 Jan 9.

30.

Versatile Flexible Graphene Multielectrode Arrays.

Kireev D, Seyock S, Ernst M, Maybeck V, Wolfrum B, Offenhäusser A.

Biosensors (Basel). 2016 Dec 23;7(1). pii: E1. doi: 10.3390/bios7010001.

31.

Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors.

Wang X, Liu J, Zhang W, Stashko MA, Nichols J, Miley MJ, Norris-Drouin J, Chen Z, Machius M, DeRyckere D, Wood E, Graham DK, Earp HS, Kireev D, Frye SV.

ACS Med Chem Lett. 2016 Sep 13;7(12):1044-1049. eCollection 2016 Dec 8.

32.

A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors.

Baughman BM, Wang H, An Y, Kireev D, Stashko MA, Jessen HJ, Pearce KH, Frye SV, Shears SB.

PLoS One. 2016 Oct 13;11(10):e0164378. doi: 10.1371/journal.pone.0164378. eCollection 2016. Retraction in: PLoS One. 2017 Jun 21;12 (6):e0180272.

33.

Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.

Simpson C, Jones NG, Hull-Ryde EA, Kireev D, Stashko M, Tang K, Janetka J, Wildman SA, Zuercher WJ, Schapira M, Hui R, Janzen W, Sibley LD.

ACS Infect Dis. 2016 Mar 11;2(3):194-206. Epub 2015 Dec 28.

34.

Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing.

Barnash KD, Lamb KN, Stuckey JI, Norris JL, Cholensky SH, Kireev DB, Frye SV, James LI.

ACS Chem Biol. 2016 Sep 16;11(9):2475-83. doi: 10.1021/acschembio.6b00415. Epub 2016 Jul 14.

35.

Structure-Based Virtual Screening of Commercially Available Compound Libraries.

Kireev D.

Methods Mol Biol. 2016;1439:65-76. doi: 10.1007/978-1-4939-3673-1_4.

PMID:
27316988
36.

The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia.

Minson KA, Smith CC, DeRyckere D, Libbrecht C, Lee-Sherick AB, Huey MG, Lasater EA, Kirkpatrick GD, Stashko MA, Zhang W, Jordan CT, Kireev D, Wang X, Frye SV, Earp HS, Shah NP, Graham DK.

JCI Insight. 2016 Mar;1(3):e85630. doi: 10.1172/jci.insight.85630.

37.

Electrolyte-Gated Graphene Ambipolar Frequency Multipliers for Biochemical Sensing.

Fu W, Feng L, Mayer D, Panaitov G, Kireev D, Offenhäusser A, Krause HJ.

Nano Lett. 2016 Apr 13;16(4):2295-300. doi: 10.1021/acs.nanolett.5b04729. Epub 2016 Mar 3.

PMID:
26928906
38.

Discovery of Mer kinase inhibitors by virtual screening using Structural Protein-Ligand Interaction Fingerprints.

Da C, Stashko M, Jayakody C, Wang X, Janzen W, Frye S, Kireev D.

Bioorg Med Chem. 2015 Mar 1;23(5):1096-101. doi: 10.1016/j.bmc.2015.01.001. Epub 2015 Jan 13.

39.

Development of a High-Throughput Screening Assay to Identify Inhibitors of the Lipid Kinase PIP5K1C.

Wright BD, Simpson C, Stashko M, Kireev D, Hull-Ryde EA, Zylka MJ, Janzen WP.

J Biomol Screen. 2015 Jun;20(5):655-62. doi: 10.1177/1087057114564057. Epub 2014 Dec 22.

40.

Development and validation of protocol for HIV-1 detection in washed sperm before medically assisted procreation.

Dmitryukova M, Kireev D, Lopatukhin A, Kvashnina E, Balezin S, Portnov I, Potokij N, Shipulin G.

Gynecol Endocrinol. 2014 Oct;30 Suppl 1:20-1. doi: 10.3109/09513590.2014.945773.

PMID:
25200822
41.

Structural protein-ligand interaction fingerprints (SPLIF) for structure-based virtual screening: method and benchmark study.

Da C, Kireev D.

J Chem Inf Model. 2014 Sep 22;54(9):2555-61. doi: 10.1021/ci500319f. Epub 2014 Aug 20.

42.

UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor.

Zhang W, DeRyckere D, Hunter D, Liu J, Stashko MA, Minson KA, Cummings CT, Lee M, Glaros TG, Newton DL, Sather S, Zhang D, Kireev D, Janzen WP, Earp HS, Graham DK, Frye SV, Wang X.

J Med Chem. 2014 Aug 28;57(16):7031-41. doi: 10.1021/jm500749d. Epub 2014 Aug 6.

43.

The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface.

Camerino MA, Zhong N, Dong A, Dickson BM, James LI, Baughman BM, Norris JL, Kireev DB, Janzen WP, Arrowsmith CH, Frye SV.

Medchemcomm. 2013 Nov;4(11):1501-1507.

44.

[The first experience of application of standardized genotype technique of identification of HIV-tropism].

Lopatukhin AÉ, Kireev DE, Poliakov AN, Bukin EK, Kaiser R, Luebke N, Kuevda DA, Shipulin GA.

Klin Lab Diagn. 2013 Jun;(6):46-8. Russian.

PMID:
24340948
45.

Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis.

Zhang W, McIver AL, Stashko MA, DeRyckere D, Branchford BR, Hunter D, Kireev D, Miley MJ, Norris-Drouin J, Stewart WM, Lee M, Sather S, Zhou Y, Di Paola JA, Machius M, Janzen WP, Earp HS, Graham DK, Frye SV, Wang X.

J Med Chem. 2013 Dec 12;56(23):9693-700. doi: 10.1021/jm4013888. Epub 2013 Nov 20.

46.

Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors.

Zhang W, Zhang D, Stashko MA, DeRyckere D, Hunter D, Kireev D, Miley MJ, Cummings C, Lee M, Norris-Drouin J, Stewart WM, Sather S, Zhou Y, Kirkpatrick G, Machius M, Janzen WP, Earp HS, Graham DK, Frye SV, Wang X.

J Med Chem. 2013 Dec 12;56(23):9683-92. doi: 10.1021/jm401387j. Epub 2013 Nov 20. Erratum in: J Med Chem. 2014 Aug 28;57(16):7141.

47.

Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3.

James LI, Korboukh VK, Krichevsky L, Baughman BM, Herold JM, Norris JL, Jin J, Kireev DB, Janzen WP, Arrowsmith CH, Frye SV.

J Med Chem. 2013 Sep 26;56(18):7358-71. doi: 10.1021/jm400919p. Epub 2013 Sep 16.

48.

UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.

Christoph S, Deryckere D, Schlegel J, Frazer JK, Batchelor LA, Trakhimets AY, Sather S, Hunter DM, Cummings CT, Liu J, Yang C, Kireev D, Simpson C, Norris-Drouin J, Hull-Ryde EA, Janzen WP, Johnson GL, Wang X, Frye SV, Earp HS 3rd, Graham DK.

Mol Cancer Ther. 2013 Nov;12(11):2367-77. doi: 10.1158/1535-7163.MCT-13-0040. Epub 2013 Aug 30.

49.

Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation.

Rothbart SB, Dickson BM, Ong MS, Krajewski K, Houliston S, Kireev DB, Arrowsmith CH, Strahl BD.

Genes Dev. 2013 Jun 1;27(11):1288-98. doi: 10.1101/gad.220467.113.

50.

UNC1062, a new and potent Mer inhibitor.

Liu J, Zhang W, Stashko MA, Deryckere D, Cummings CT, Hunter D, Yang C, Jayakody CN, Cheng N, Simpson C, Norris-Drouin J, Sather S, Kireev D, Janzen WP, Earp HS, Graham DK, Frye SV, Wang X.

Eur J Med Chem. 2013 Jul;65:83-93. doi: 10.1016/j.ejmech.2013.03.035. Epub 2013 Apr 2.

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