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Items: 1 to 50 of 189

1.

Parsing the Patients of FREEDOM.

Blankenship JC, Kirchner HL.

J Am Coll Cardiol. 2019 Oct 22;74(16):2085-2087. doi: 10.1016/j.jacc.2019.08.1010. No abstract available.

PMID:
31623767
2.

Patient assessment of chatbots for the scalable delivery of genetic counseling.

Schmidlen T, Schwartz M, DiLoreto K, Kirchner HL, Sturm AC.

J Genet Couns. 2019 Sep 24. doi: 10.1002/jgc4.1169. [Epub ahead of print]

PMID:
31549758
3.

Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems.

Zheutlin AB, Dennis J, Karlsson Linnér R, Moscati A, Restrepo N, Straub P, Ruderfer D, Castro VM, Chen CY, Ge T, Huckins LM, Charney A, Kirchner HL, Stahl EA, Chabris CF, Davis LK, Smoller JW.

Am J Psychiatry. 2019 Oct 1;176(10):846-855. doi: 10.1176/appi.ajp.2019.18091085. Epub 2019 Aug 16.

PMID:
31416338
4.

Routinely reported ejection fraction and mortality in clinical practice: where does the nadir of risk lie?

Wehner GJ, Jing L, Haggerty CM, Suever JD, Leader JB, Hartzel DN, Kirchner HL, Manus JNA, James N, Ayar Z, Gladding P, Good CW, Cleland JGF, Fornwalt BK.

Eur Heart J. 2019 Aug 6. pii: ehz550. doi: 10.1093/eurheartj/ehz550. [Epub ahead of print]

PMID:
31386109
5.

Social and Psychological Risk and Protective Factors for Veteran Well-Being: The Role of Veteran Identity and Its Implications for Intervention.

Adams RE, Urosevich TG, Hoffman SN, Kirchner HL, Figley CR, Withey CA, Boscarino JJ, Dugan RJ, Boscarino JA.

Mil Behav Health. 2019;7(3):304-314. doi: 10.1080/21635781.2019.1580642. Epub 2019 Mar 12.

6.

Grapheme-Color Synesthesia is Associated with PTSD Among Deployed Veterans: Confirmation of Previous Findings and Need for Additional Research.

Hoffman SN, Urosevich TG, Kirchner HL, Boscarino JJ, Dugan RJ, Withey CA, Adams RE, Figley CR, Boscarino JA.

Int J Emerg Ment Health. 2019;21(1). pii: https://www.omicsonline.org/open-access/graphemecolor-synesthesia-is-associated-with-ptsd-among-deployed-veterans-confirmation-of-previous-findings-and-need-for-additiona-1522-4821-108513.html.

7.

Hidden Burden of Electronic Health Record-Identified Familial Hypercholesterolemia: Clinical Outcomes and Cost of Medical Care.

Patel P, Hu Y, Kolinovsky A, Geng Z, Ruhl J, Krishnamurthy S, deRichemond C, Khan A, Kirchner HL, Metpally R, Jones LK, Sturm AC, Carey D, Snyder S, Williams MS, Mehra VC.

J Am Heart Assoc. 2019 Jul 2;8(13):e011822. doi: 10.1161/JAHA.118.011822. Epub 2019 Jun 29.

8.

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.

Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, Chen S, Contreras-Cubas C, Córdova E, Correa A, Cortes M, DeFronzo RA, Dolan L, Drews KL, Elliott A, Floyd JS, Gabriel S, Garay-Sevilla ME, García-Ortiz H, Gross M, Han S, Heard-Costa NL, Jackson AU, Jørgensen ME, Kang HM, Kelsey M, Kim BJ, Koistinen HA, Kuusisto J, Leader JB, Linneberg A, Liu CT, Liu J, Lyssenko V, Manning AK, Marcketta A, Malacara-Hernandez JM, Martínez-Hernández A, Matsuo K, Mayer-Davis E, Mendoza-Caamal E, Mohlke KL, Morrison AC, Ndungu A, Ng MCY, O'Dushlaine C, Payne AJ, Pihoker C; Broad Genomics Platform, Post WS, Preuss M, Psaty BM, Vasan RS, Rayner NW, Reiner AP, Revilla-Monsalve C, Robertson NR, Santoro N, Schurmann C, So WY, Soberón X, Stringham HM, Strom TM, Tam CHT, Thameem F, Tomlinson B, Torres JM, Tracy RP, van Dam RM, Vujkovic M, Wang S, Welch RP, Witte DR, Wong TY, Atzmon G, Barzilai N, Blangero J, Bonnycastle LL, Bowden DW, Chambers JC, Chan E, Cheng CY, Cho YS, Collins FS, de Vries PS, Duggirala R, Glaser B, Gonzalez C, Gonzalez ME, Groop L, Kooner JS, Kwak SH, Laakso M, Lehman DM, Nilsson P, Spector TD, Tai ES, Tuomi T, Tuomilehto J, Wilson JG, Aguilar-Salinas CA, Bottinger E, Burke B, Carey DJ, Chan JCN, Dupuis J, Frossard P, Heckbert SR, Hwang MY, Kim YJ, Kirchner HL, Lee JY, Lee J, Loos RJF, Ma RCW, Morris AD, O'Donnell CJ, Palmer CNA, Pankow J, Park KS, Rasheed A, Saleheen D, Sim X, Small KS, Teo YY, Haiman C, Hanis CL, Henderson BE, Orozco L, Tusié-Luna T, Dewey FE, Baras A, Gieger C, Meitinger T, Strauch K, Lange L, Grarup N, Hansen T, Pedersen O, Zeitler P, Dabelea D, Abecasis G, Bell GI, Cox NJ, Seielstad M, Sladek R, Meigs JB, Rich SS, Rotter JI; DiscovEHR Collaboration; CHARGE; LuCamp; ProDiGY; GoT2D; ESP; SIGMA-T2D; T2D-GENES; AMP-T2D-GENES, Altshuler D, Burtt NP, Scott LJ, Morris AP, Florez JC, McCarthy MI, Boehnke M.

Nature. 2019 Jun;570(7759):71-76. doi: 10.1038/s41586-019-1231-2. Epub 2019 May 22.

9.

Guard/Reserve service members and mental health outcomes following deployment: Results from the Veterans' Health Study.

Boscarino JA, Adams RE, Urosevich TG, Hoffman SN, Kirchner HL, Dugan RJ, Boscarino JJ, Withey CA, Figley CR.

Gen Hosp Psychiatry. 2019 Mar 15. pii: S0163-8343(19)30109-4. doi: 10.1016/j.genhosppsych.2019.03.002. [Epub ahead of print] No abstract available.

PMID:
30910352
10.

Endoscopic ultrasound-guided biopsy in chronic liver disease: a randomized comparison of 19-G FNA and 22-G FNB needles.

Mok SRS, Diehl DL, Johal AS, Khara HS, Confer BD, Mudireddy PR, Kovach AH, Diehl MM, Kirchner HL, Chen ZE.

Endosc Int Open. 2019 Jan;7(1):E62-E71. doi: 10.1055/a-0655-7462. Epub 2019 Jan 4.

11.

Exome Sequencing-Based Screening for BRCA1/2 Expected Pathogenic Variants Among Adult Biobank Participants.

Manickam K, Buchanan AH, Schwartz MLB, Hallquist MLG, Williams JL, Rahm AK, Rocha H, Savatt JM, Evans AE, Butry LM, Lazzeri AL, Lindbuchler DM, Flansburg CN, Leeming R, Vogel VG, Lebo MS, Mason-Suares HM, Hoskinson DC, Abul-Husn NS, Dewey FE, Overton JD, Reid JG, Baras A, Willard HF, McCormick CZ, Krishnamurthy SB, Hartzel DN, Kost KA, Lavage DR, Sturm AC, Frisbie LR, Person TN, Metpally RP, Giovanni MA, Lowry LE, Leader JB, Ritchie MD, Carey DJ, Justice AE, Kirchner HL, Faucett WA, Williams MS, Ledbetter DH, Murray MF.

JAMA Netw Open. 2018 Sep 7;1(5):e182140. doi: 10.1001/jamanetworkopen.2018.2140.

12.

Reply to Association between treatment of superficial bladder cancer and 10-year mortality in older adults with multiple chronic conditions.

Garg T, Young AJ, O'Keeffe-Rosetti M, McMullen CK, Nielsen ME, Kirchner HL, Murphy TE.

Cancer. 2019 Feb 15;125(4):652-653. doi: 10.1002/cncr.31894. Epub 2018 Dec 5. No abstract available.

PMID:
30516841
13.

Association between treatment of superficial bladder cancer and 10-year mortality in older adults with multiple chronic conditions.

Garg T, Young AJ, O'Keeffe-Rosetti M, McMullen CK, Nielsen ME, Kirchner HL, Murphy TE.

Cancer. 2018 Dec 1;124(23):4477-4485. doi: 10.1002/cncr.31705. Epub 2018 Oct 5.

PMID:
30289971
14.

Mental Health Impact of Homecoming Experience Among 1730 Formerly Deployed Veterans From the Vietnam War to Current Conflicts: Results From the Veterans' Health Study.

Boscarino JA, Adams RE, Urosevich TG, Hoffman SN, Kirchner HL, Boscarino JJ, Withey CA, Dugan RJ, Figley CR.

J Nerv Ment Dis. 2018 Oct;206(10):757-764. doi: 10.1097/NMD.0000000000000879.

15.

Demographic, clinical, and behavioral determinants of 7-year weight change trajectories in Roux-en-Y gastric bypass patients.

Lent MR, Hu Y, Benotti PN, Petrick AT, Wood GC, Still CD, Kirchner HL.

Surg Obes Relat Dis. 2018 Nov;14(11):1680-1685. doi: 10.1016/j.soard.2018.07.023. Epub 2018 Jul 30.

PMID:
30166262
16.

Perioperative diltiazem or nitroglycerin in on-pump coronary artery bypass: A systematic review and network meta-analysis.

Hu Y, Yang X, Zhang L, Wu X, Liu AY, Boscarino JA, Kirchner HL, Casale AS, Zhang X.

PLoS One. 2018 Aug 30;13(8):e0203315. doi: 10.1371/journal.pone.0203315. eCollection 2018.

17.

A prospective pilot comparison of wet and dry heparinized suction for EUS-guided liver biopsy (with videos).

Mok SRS, Diehl DL, Johal AS, Khara HS, Confer BD, Mudireddy PR, Kirchner HL, Chen ZE.

Gastrointest Endosc. 2018 Dec;88(6):919-925. doi: 10.1016/j.gie.2018.07.036. Epub 2018 Aug 16.

PMID:
30120956
18.

Identifying Asthma Exacerbation-Related Emergency Department Visit Using Electronic Medical Record and Claims Data.

Sundaresan AS, Schneider G, Reynolds J, Kirchner HL.

Appl Clin Inform. 2018 Jul;9(3):528-540. doi: 10.1055/s-0038-1666994. Epub 2018 Jul 18.

19.

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

Gusarova V, O'Dushlaine C, Teslovich TM, Benotti PN, Mirshahi T, Gottesman O, Van Hout CV, Murray MF, Mahajan A, Nielsen JB, Fritsche L, Wulff AB, Gudbjartsson DF, Sjögren M, Emdin CA, Scott RA, Lee WJ, Small A, Kwee LC, Dwivedi OP, Prasad RB, Bruse S, Lopez AE, Penn J, Marcketta A, Leader JB, Still CD, Kirchner HL, Mirshahi UL, Wardeh AH, Hartle CM, Habegger L, Fetterolf SN, Tusie-Luna T, Morris AP, Holm H, Steinthorsdottir V, Sulem P, Thorsteinsdottir U, Rotter JI, Chuang LM, Damrauer S, Birtwell D, Brummett CM, Khera AV, Natarajan P, Orho-Melander M, Flannick J, Lotta LA, Willer CJ, Holmen OL, Ritchie MD, Ledbetter DH, Murphy AJ, Borecki IB, Reid JG, Overton JD, Hansson O, Groop L, Shah SH, Kraus WE, Rader DJ, Chen YI, Hveem K, Wareham NJ, Kathiresan S, Melander O, Stefansson K, Nordestgaard BG, Tybjærg-Hansen A, Abecasis GR, Altshuler D, Florez JC, Boehnke M, McCarthy MI, Yancopoulos GD, Carey DJ, Shuldiner AR, Baras A, Dewey FE, Gromada J.

Nat Commun. 2018 Jun 13;9(1):2252. doi: 10.1038/s41467-018-04611-z.

20.

Visual Dysfunction and Associated Co-morbidities as Predictors of Mild Traumatic Brain Injury Seen Among Veterans in Non-VA Facilities: Implications for Clinical Practice.

Urosevich TG, Boscarino JJ, Hoffman SN, Kirchner HL, Figley CR, Adams RE, Withey CA, Boscarino JA.

Mil Med. 2018 Nov 1;183(11-12):e564-e570. doi: 10.1093/milmed/usy102.

21.

Profiling and Leveraging Relatedness in a Precision Medicine Cohort of 92,455 Exomes.

Staples J, Maxwell EK, Gosalia N, Gonzaga-Jauregui C, Snyder C, Hawes A, Penn J, Ulloa R, Bai X, Lopez AE, Van Hout CV, O'Dushlaine C, Teslovich TM, McCarthy SE, Balasubramanian S, Kirchner HL, Leader JB, Murray MF, Ledbetter DH, Shuldiner AR, Yancoupolos GD, Dewey FE, Carey DJ, Overton JD, Baras A, Habegger L, Reid JG.

Am J Hum Genet. 2018 May 3;102(5):874-889. doi: 10.1016/j.ajhg.2018.03.012.

22.

Heparin priming of EUS-FNA needles does not adversely affect tissue cytology or immunohistochemical staining.

Diehl DL, Mok SRS, Khara HS, Johal AS, Kirchner HL, Lin F.

Endosc Int Open. 2018 Mar;6(3):E356-E362. doi: 10.1055/s-0043-121880. Epub 2018 Mar 7.

23.

Metabolically Healthy Obesity and Risk of Kidney Function Decline.

Chang AR, Surapaneni A, Kirchner HL, Young A, Kramer HJ, Carey DJ, Appel LJ, Grams ME.

Obesity (Silver Spring). 2018 Apr;26(4):762-768. doi: 10.1002/oby.22134. Epub 2018 Mar 2.

24.

Improved Gout Outcomes in Primary Care Using a Novel Disease Management Program: A Pilot Study.

Bulbin D, Denio AE, Berger A, Brown J, Maynard C, Sharma T, Kirchner HL, Ayoub WT.

Arthritis Care Res (Hoboken). 2018 Nov;70(11):1679-1685. doi: 10.1002/acr.23544.

PMID:
29438607
25.

Trends in Survival After In-Hospital Cardiac Arrest During Nights and Weekends.

Ofoma UR, Basnet S, Berger A, Kirchner HL, Girotra S; American Heart Association Get With the Guidelines – Resuscitation Investigators.

J Am Coll Cardiol. 2018 Jan 30;71(4):402-411. doi: 10.1016/j.jacc.2017.11.043.

26.

Culture-Negative Septic Shock Compared With Culture-Positive Septic Shock: A Retrospective Cohort Study.

Kethireddy S, Bilgili B, Sees A, Kirchner HL, Ofoma UR, Light RB, Mirzanejad Y, Maki D, Kumar A, Layon AJ, Parrillo JE, Kumar A; Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group.

Crit Care Med. 2018 Apr;46(4):506-512. doi: 10.1097/CCM.0000000000002924.

PMID:
29293143
27.

T-SPOT.TB Performance in Routine Pediatric Practice in a Low TB Burden Setting.

Mandalakas AM, Highsmith HY, Harris NM, Pawlicka A, Kirchner HL.

Pediatr Infect Dis J. 2018 Apr;37(4):292-297. doi: 10.1097/INF.0000000000001792.

PMID:
29140933
28.

Ambulatory systolic blood pressure and obesity are independently associated with left ventricular hypertrophic remodeling in children.

Jing L, Nevius CD, Friday CM, Suever JD, Pulenthiran A, Mejia-Spiegeler A, Kirchner HL, Cochran WJ, Wehner GJ, Chishti AS, Haggerty CM, Fornwalt BK.

J Cardiovasc Magn Reson. 2017 Nov 9;19(1):86. doi: 10.1186/s12968-017-0401-3.

29.

Social Support, Help-Seeking, and Mental Health Outcomes Among Veterans in Non-VA Facilities: Results from the Veterans' Health Study.

Adams RE, Urosevich TG, Hoffman SN, Kirchner HL, Hyacinthe JC, Figley CR, Boscarino JJ, Boscarino JA.

Mil Behav Health. 2017;5(4):393-405. doi: 10.1080/21635781.2017.1333067. Epub 2017 May 19.

30.

Patient-reported quality of life recovery curves after robotic prostatectomy are similar across body mass index categories.

Garg T, Young AJ, Kost KA, Park AM, Danella JF, Kirchner HL.

Investig Clin Urol. 2017 Sep;58(5):331-338. doi: 10.4111/icu.2017.58.5.331. Epub 2017 Aug 3.

31.

Burden of Multiple Chronic Conditions among Patients with Urological Cancer.

Garg T, Young AJ, Kost KA, Danella JF, Larson S, Nielsen ME, Kirchner HL.

J Urol. 2018 Feb;199(2):543-550. doi: 10.1016/j.juro.2017.08.005. Epub 2017 Aug 5.

PMID:
28789948
32.

Impaired right ventricular contractile function in childhood obesity and its association with right and left ventricular changes: a cine DENSE cardiac magnetic resonance study.

Jing L, Pulenthiran A, Nevius CD, Mejia-Spiegeler A, Suever JD, Wehner GJ, Kirchner HL, Haggerty CM, Fornwalt BK.

J Cardiovasc Magn Reson. 2017 Jun 28;19(1):49. doi: 10.1186/s12968-017-0363-5.

33.

Attitudes about Future Genetic Testing for Posttraumatic Stress Disorder and Addiction among Community-Based Veterans.

Lent MR, Hoffman SN, Kirchner HL, Urosevich TG, Boscarino JJ, Boscarino JA.

Front Psychiatry. 2017 May 15;8:76. doi: 10.3389/fpsyt.2017.00076. eCollection 2017.

34.

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.

Dewey FE, Gusarova V, Dunbar RL, O'Dushlaine C, Schurmann C, Gottesman O, McCarthy S, Van Hout CV, Bruse S, Dansky HM, Leader JB, Murray MF, Ritchie MD, Kirchner HL, Habegger L, Lopez A, Penn J, Zhao A, Shao W, Stahl N, Murphy AJ, Hamon S, Bouzelmat A, Zhang R, Shumel B, Pordy R, Gipe D, Herman GA, Sheu WHH, Lee IT, Liang KW, Guo X, Rotter JI, Chen YI, Kraus WE, Shah SH, Damrauer S, Small A, Rader DJ, Wulff AB, Nordestgaard BG, Tybjærg-Hansen A, van den Hoek AM, Princen HMG, Ledbetter DH, Carey DJ, Overton JD, Reid JG, Sasiela WJ, Banerjee P, Shuldiner AR, Borecki IB, Teslovich TM, Yancopoulos GD, Mellis SJ, Gromada J, Baras A.

N Engl J Med. 2017 Jul 20;377(3):211-221. doi: 10.1056/NEJMoa1612790. Epub 2017 May 24.

35.

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.

Nomura A, Won HH, Khera AV, Takeuchi F, Ito K, McCarthy S, Emdin CA, Klarin D, Natarajan P, Zekavat SM, Gupta N, Peloso GM, Borecki IB, Teslovich TM, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Carey DJ, Murray MF, Kirchner HL, Leader JB, Lavage DR, Manus JN, Hartze DN, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Juang JJ, Hsiung CA, Lin SY, Wang JS, Tada H, Kawashiri MA, Inazu A, Yamagishi M, Katsuya T, Nakashima E, Nakatochi M, Yamamoto K, Yokota M, Momozawa Y, Rotter JI, Lander ES, Rader DJ, Danesh J, Ardissino D, Gabriel S, Willer CJ, Abecasis GR, Saleheen D, Kubo M, Kato N, Ida Chen YD, Dewey FE, Kathiresan S.

Circ Res. 2017 Jun 23;121(1):81-88. doi: 10.1161/CIRCRESAHA.117.311145. Epub 2017 May 15.

36.

Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease.

Khera AV, Won HH, Peloso GM, O'Dushlaine C, Liu D, Stitziel NO, Natarajan P, Nomura A, Emdin CA, Gupta N, Borecki IB, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Carey DJ, Murray MF, Kirchner HL, Leader JB, Lavage DR, Manus JN, Hartzel DN, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Lander ES, Rader DJ, Danesh J, Ardissino D, Gabriel S, Willer C, Abecasis GR, Saleheen D, Dewey FE, Kathiresan S; Myocardial Infarction Genetics Consortium, DiscovEHR Study Group, CARDIoGRAM Exome Consortium, and Global Lipids Genetics Consortium.

JAMA. 2017 Mar 7;317(9):937-946. doi: 10.1001/jama.2017.0972.

37.

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, Obeidat M, Henry AP, Portelli MA, Hall RJ, Billington CK, Rimington TL, Fenech AG, John C, Blake T, Jackson VE, Allen RJ, Prins BP; Understanding Society Scientific Group, Campbell A, Porteous DJ, Jarvelin MR, Wielscher M, James AL, Hui J, Wareham NJ, Zhao JH, Wilson JF, Joshi PK, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch NM, Karrasch S, Gieger C, Deary IJ, Harris SE, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr SM, Polasek O, Kähönen M, Surakka I, Vitart V, Hayward C, Lehtimäki T, Raitakari OT, Evans DM, Henderson AJ, Pennell CE, Wang CA, Sly PD, Wan ES, Busch R, Hobbs BD, Litonjua AA, Sparrow DW, Gulsvik A, Bakke PS, Crapo JD, Beaty TH, Hansel NN, Mathias RA, Ruczinski I, Barnes KC, Bossé Y, Joubert P, van den Berge M, Brandsma CA, Paré PD, Sin DD, Nickle DC, Hao K, Gottesman O, Dewey FE, Bruse SE, Carey DJ, Kirchner HL; Geisinger-Regeneron DiscovEHR Collaboration, Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger EP, Loos RJ, Walters RG, Chen Z, Millwood IY, Vaucher J, Kurmi OP, Li L, Hansell AL, Brightling C, Zeggini E, Cho MH, Silverman EK, Sayers I, Trynka G, Morris AP, Strachan DP, Hall IP, Tobin MD.

Nat Genet. 2017 Mar;49(3):416-425. doi: 10.1038/ng.3787. Epub 2017 Feb 6.

38.

Investigating the prognostic value of KOC (K homology domain containing protein overexpressed in cancer) overexpression after curative intent resection of pancreatic ductal adenocarcinoma.

Johnson B, Khalil M, Blansfield J, Lin F, Zhu S, Kirchner HL, Weir AB 3rd.

J Gastrointest Oncol. 2016 Dec;7(6):E113-E117. doi: 10.21037/jgo.2016.11.05.

39.

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study.

Dewey FE, Murray MF, Overton JD, Habegger L, Leader JB, Fetterolf SN, O'Dushlaine C, Van Hout CV, Staples J, Gonzaga-Jauregui C, Metpally R, Pendergrass SA, Giovanni MA, Kirchner HL, Balasubramanian S, Abul-Husn NS, Hartzel DN, Lavage DR, Kost KA, Packer JS, Lopez AE, Penn J, Mukherjee S, Gosalia N, Kanagaraj M, Li AH, Mitnaul LJ, Adams LJ, Person TN, Praveen K, Marcketta A, Lebo MS, Austin-Tse CA, Mason-Suares HM, Bruse S, Mellis S, Phillips R, Stahl N, Murphy A, Economides A, Skelding KA, Still CD, Elmore JR, Borecki IB, Yancopoulos GD, Davis FD, Faucett WA, Gottesman O, Ritchie MD, Shuldiner AR, Reid JG, Ledbetter DH, Baras A, Carey DJ.

Science. 2016 Dec 23;354(6319). pii: aaf6814. doi: 10.1126/science.aaf6814.

PMID:
28008009
40.

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, Hartwig FP, Horta BL, Hyppönen E, Power C, Moldovan M, van Iperen E, Hovingh GK, Demuth I, Norman K, Steinhagen-Thiessen E, Demuth J, Bertram L, Liu T, Coassin S, Willeit J, Kiechl S, Willeit K, Mason D, Wright J, Morris R, Wanamethee G, Whincup P, Ben-Shlomo Y, McLachlan S, Price JF, Kivimaki M, Welch C, Sanchez-Galvez A, Marques-Vidal P, Nicolaides A, Panayiotou AG, Onland-Moret NC, van der Schouw YT, Matullo G, Fiorito G, Guarrera S, Sacerdote C, Wareham NJ, Langenberg C, Scott R, Luan J, Bobak M, Malyutina S, Pająk A, Kubinova R, Tamosiunas A, Pikhart H, Husemoen LL, Grarup N, Pedersen O, Hansen T, Linneberg A, Simonsen KS, Cooper J, Humphries SE, Brilliant M, Kitchner T, Hakonarson H, Carrell DS, McCarty CA, Kirchner HL, Larson EB, Crosslin DR, de Andrade M, Roden DM, Denny JC, Carty C, Hancock S, Attia J, Holliday E, O'Donnell M, Yusuf S, Chong M, Pare G, van der Harst P, Said MA, Eppinga RN, Verweij N, Snieder H; LifeLines Cohort study group, Christen T, Mook-Kanamori DO, Gustafsson S, Lind L, Ingelsson E, Pazoki R, Franco O, Hofman A, Uitterlinden A, Dehghan A, Teumer A, Baumeister S, Dörr M, Lerch MM, Völker U, Völzke H, Ward J, Pell JP, Smith DJ, Meade T, Maitland-van der Zee AH, Baranova EV, Young R, Ford I, Campbell A, Padmanabhan S, Bots ML, Grobbee DE, Froguel P, Thuillier D, Balkau B, Bonnefond A, Cariou B, Smart M, Bao Y, Kumari M, Mahajan A, Ridker PM, Chasman DI, Reiner AP, Lange LA, Ritchie MD, Asselbergs FW, Casas JP, Keating BJ, Preiss D, Hingorani AD; UCLEB consortium, Sattar N.

Lancet Diabetes Endocrinol. 2017 Feb;5(2):97-105. doi: 10.1016/S2213-8587(16)30396-5. Epub 2016 Nov 29.

41.

Using pharmacists to improve risk stratification and management of stage 3A chronic kidney disease: a feasibility study.

Chang AR, Evans M, Yule C, Bohn L, Young A, Lewis M, Graboski E, Gerdy B, Ehmann W, Brady J, Lawrence L, Antunes N, Green J, Snyder S, Kirchner HL, Grams M, Perkins R.

BMC Nephrol. 2016 Nov 8;17(1):168.

42.

Factors associated with opioid overdose: a 10-year retrospective study of patients in a large integrated health care system.

Boscarino JA, Kirchner HL, Pitcavage JM, Nadipelli VR, Ronquest NA, Fitzpatrick MH, Han JJ.

Subst Abuse Rehabil. 2016 Sep 16;7:131-141. eCollection 2016.

43.

No association of labor epidural analgesia with cerebral palsy in children.

Zhang L, Graham JH, Feng W, Lewis MW, Zhang X, Kirchner HL.

J Anesth. 2016 Dec;30(6):1008-1013. doi: 10.1007/s00540-016-2244-8. Epub 2016 Sep 2.

PMID:
27590523
44.

Corrigendum to Baseline Undertreatment of Adults with Newly Diagnosed Familial Hypercholesterolemia by Genomic Sequencing [J Clin Lipidol 10 (2016) 692-693].

Jones L, Wright E, Hartzel D, Lindbuchler D, Leader J, Kirchner HL, Overton J, Reid J, Evans M, Dewey F, Murray M.

J Clin Lipidol. 2016 Jul - Aug;10(4):1053. doi: 10.1016/j.jacl.2016.06.004. Epub 2016 Aug 27. No abstract available.

PMID:
27578142
45.

Utilizing bi-spectral index (BIS) for the monitoring of sedated adult ICU patients: a systematic review.

Bilgili B, Montoya JC, Layon AJ, Berger AL, Kirchner HL, Gupta LK, Gloss DS.

Minerva Anestesiol. 2017 Mar;83(3):288 - 301. doi: 10.23736/S0375-9393.16.10886-7. Epub 2016 Jun 17.

46.

Bariatric surgery is associated with improvement in kidney outcomes.

Chang AR, Chen Y, Still C, Wood GC, Kirchner HL, Lewis M, Kramer H, Hartle JE, Carey D, Appel LJ, Grams ME.

Kidney Int. 2016 Jul;90(1):164-71. doi: 10.1016/j.kint.2016.02.039. Epub 2016 May 12.

47.

Cardiac remodeling and dysfunction in childhood obesity: a cardiovascular magnetic resonance study.

Jing L, Binkley CM, Suever JD, Umasankar N, Haggerty CM, Rich J, Wehner GJ, Hamlet SM, Powell DK, Radulescu A, Kirchner HL, Epstein FH, Fornwalt BK.

J Cardiovasc Magn Reson. 2016 May 11;18(1):28. doi: 10.1186/s12968-016-0247-0.

48.

Echocardiography-Defined Pulmonary Hypertension in Multiple Myeloma: Risk Factors and Impact on Outcomes.

Sangani RG, Butler M, Kirchner HL, Berger A, Stamm JA.

South Med J. 2016 May;109(5):282-9. doi: 10.14423/SMJ.0000000000000461.

PMID:
27135723
49.

Antihypertensive Medications and the Prevalence of Hyperkalemia in a Large Health System.

Chang AR, Sang Y, Leddy J, Yahya T, Kirchner HL, Inker LA, Matsushita K, Ballew SH, Coresh J, Grams ME.

Hypertension. 2016 Jun;67(6):1181-8. doi: 10.1161/HYPERTENSIONAHA.116.07363. Epub 2016 Apr 11.

50.

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

Dewey FE, Gusarova V, O'Dushlaine C, Gottesman O, Trejos J, Hunt C, Van Hout CV, Habegger L, Buckler D, Lai KM, Leader JB, Murray MF, Ritchie MD, Kirchner HL, Ledbetter DH, Penn J, Lopez A, Borecki IB, Overton JD, Reid JG, Carey DJ, Murphy AJ, Yancopoulos GD, Baras A, Gromada J, Shuldiner AR.

N Engl J Med. 2016 Mar 24;374(12):1123-33. doi: 10.1056/NEJMoa1510926. Epub 2016 Mar 2.

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