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Items: 1 to 50 of 348

1.

Key Viral Adaptations Preceding the AIDS Pandemic.

Sauter D, Kirchhoff F.

Cell Host Microbe. 2019 Jan 9;25(1):27-38. doi: 10.1016/j.chom.2018.12.002. Review.

PMID:
30629915
2.

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments.

Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet JP, Bezzi P.

Mol Psychiatry. 2018 Aug 20. doi: 10.1038/s41380-018-0226-y. [Epub ahead of print]

PMID:
30127471
3.

SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.

Kmiec D, Akbil B, Ananth S, Hotter D, Sparrer KMJ, Stürzel CM, Trautz B, Ayouba A, Peeters M, Yao Z, Stagljar I, Passos V, Zillinger T, Goffinet C, Sauter D, Fackler OT, Kirchhoff F.

PLoS Pathog. 2018 Aug 20;14(8):e1007269. doi: 10.1371/journal.ppat.1007269. eCollection 2018 Aug.

4.

HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.

Morris KL, Buffalo CZ, Stürzel CM, Heusinger E, Kirchhoff F, Ren X, Hurley JH.

Cell. 2018 Jul 26;174(3):659-671.e14. doi: 10.1016/j.cell.2018.07.004.

PMID:
30053425
5.

Successful HeartMate 3 implantation in isolated right heart failure-first in man experience of right heart configuration.

Ricklefs M, Hanke JS, Dogan G, Chatterjee A, Feldmann C, Deniz E, Korte W, Kirchhoff F, Haverich A, Schmitto JD.

J Thorac Dis. 2018 Jun;10(Suppl 15):S1834-S1837. doi: 10.21037/jtd.2018.05.35. No abstract available.

6.

Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons.

Katz E, Stoler O, Scheller A, Khrapunsky Y, Goebbels S, Kirchhoff F, Gutnick MJ, Wolf F, Fleidervish IA.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7184-E7192. doi: 10.1073/pnas.1720493115. Epub 2018 Jul 10.

PMID:
29991598
7.

Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2.

Heusinger E, Deppe K, Sette P, Krapp C, Kmiec D, Kluge SF, Marx PA, Apetrei C, Kirchhoff F, Sauter D.

J Virol. 2018 Aug 29;92(18). pii: e00276-18. doi: 10.1128/JVI.00276-18. Print 2018 Sep 15.

PMID:
29976668
8.

Comparison of different cytotoxicity assays for in vitro evaluation of mesoporous silica nanoparticles.

Braun K, Stürzel CM, Biskupek J, Kaiser U, Kirchhoff F, Lindén M.

Toxicol In Vitro. 2018 Oct;52:214-221. doi: 10.1016/j.tiv.2018.06.019. Epub 2018 Jun 22.

PMID:
29940343
9.

Reduced Susceptibility to VIRIP-Based HIV-1 Entry Inhibitors Has a High Genetic Barrier and Severe Fitness Costs.

Müller JA, Glöckle A, Gawanbacht A, Geyer M, Münch J, Kirchhoff F.

J Virol. 2018 Aug 16;92(17). pii: e00733-18. doi: 10.1128/JVI.00733-18. Print 2018 Sep 1.

PMID:
29925662
10.

Wearable Cardioverter-Defibrillators following Cardiac Surgery-A Single-Center Experience.

Heimeshoff J, Merz C, Ricklefs M, Kirchhoff F, Haverich A, Bara C, Kühn C.

Thorac Cardiovasc Surg. 2018 Jun 20. doi: 10.1055/s-0038-1660802. [Epub ahead of print]

PMID:
29925094
11.

During Development NG2 Glial Cells of the Spinal Cord are Restricted to the Oligodendrocyte Lineage, but Generate Astrocytes upon Acute Injury.

Huang W, Bai X, Stopper L, Catalin B, Cartarozzi LP, Scheller A, Kirchhoff F.

Neuroscience. 2018 Aug 10;385:154-165. doi: 10.1016/j.neuroscience.2018.06.015. Epub 2018 Jun 18.

PMID:
29913244
12.

The Antiviral Activity of the Cellular Glycoprotein LGALS3BP/90K Is Species Specific.

Lodermeyer V, Ssebyatika G, Passos V, Ponnurangam A, Malassa A, Ewald E, Stürzel CM, Kirchhoff F, Rotger M, Falk CS, Telenti A, Krey T, Goffinet C.

J Virol. 2018 Jun 29;92(14). pii: e00226-18. doi: 10.1128/JVI.00226-18. Print 2018 Jul 15.

13.

Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia.

Jahn HM, Kasakow CV, Helfer A, Michely J, Verkhratsky A, Maurer HH, Scheller A, Kirchhoff F.

Sci Rep. 2018 Apr 12;8(1):5913. doi: 10.1038/s41598-018-24085-9.

14.

Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.

Joas S, Parrish EH, Gnanadurai CW, Lump E, Stürzel CM, Parrish NF, Learn GH, Sauermann U, Neumann B, Rensing KM, Fuchs D, Billingsley JM, Bosinger SE, Silvestri G, Apetrei C, Huot N, Garcia-Tellez T, Müller-Trutwin M, Hotter D, Sauter D, Stahl-Hennig C, Hahn BH, Kirchhoff F.

Nat Commun. 2018 Apr 10;9(1):1371. doi: 10.1038/s41467-018-03762-3.

15.

Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses.

Richard J, Prévost J, Baxter AE, von Bredow B, Ding S, Medjahed H, Delgado GG, Brassard N, Stürzel CM, Kirchhoff F, Hahn BH, Parsons MS, Kaufmann DE, Evans DT, Finzi A.

MBio. 2018 Mar 20;9(2). pii: e00358-18. doi: 10.1128/mBio.00358-18.

16.

Multilayered and versatile inhibition of cellular antiviral factors by HIV and SIV accessory proteins.

Sauter D, Kirchhoff F.

Cytokine Growth Factor Rev. 2018 Apr;40:3-12. doi: 10.1016/j.cytogfr.2018.02.005. Epub 2018 Feb 23. Review.

PMID:
29526437
17.

Fibroblast growth factor 23 is induced by an activated renin-angiotensin-aldosterone system in cardiac myocytes and promotes the pro-fibrotic crosstalk between cardiac myocytes and fibroblasts.

Leifheit-Nestler M, Kirchhoff F, Nespor J, Richter B, Soetje B, Klintschar M, Heineke J, Haffner D.

Nephrol Dial Transplant. 2018 Oct 1;33(10):1722-1734. doi: 10.1093/ndt/gfy006.

PMID:
29425341
18.

In vivo two-photon imaging of motoneurons and adjacent glia in the ventral spinal cord.

Cartarozzi LP, Rieder P, Bai X, Scheller A, Oliveira ALR, Kirchhoff F.

J Neurosci Methods. 2018 Apr 1;299:8-15. doi: 10.1016/j.jneumeth.2018.01.005. Epub 2018 Feb 3.

PMID:
29408351
19.

Interferons and beyond: Induction of antiretroviral restriction factors.

Hotter D, Kirchhoff F.

J Leukoc Biol. 2018 Mar;103(3):465-477. doi: 10.1002/JLB.3MR0717-307R. Epub 2017 Dec 15. Review.

PMID:
29345347
20.

Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo.

Yamada E, Nakaoka S, Klein L, Reith E, Langer S, Hopfensperger K, Iwami S, Schreiber G, Kirchhoff F, Koyanagi Y, Sauter D, Sato K.

Cell Host Microbe. 2018 Jan 10;23(1):110-120.e7. doi: 10.1016/j.chom.2017.12.009.

21.

Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host.

Palesch D, Bosinger SE, Tharp GK, Vanderford TH, Paiardini M, Chahroudi A, Johnson ZP, Kirchhoff F, Hahn BH, Norgren RB, Patel NB, Sodora DL, Dawoud RA, Stewart CB, Seepo SM, Harris RA, Liu Y, Raveendran M, Han Y, English A, Thomas GWC, Hahn MW, Pipes L, Mason CE, Muzny DM, Gibbs RA, Sauter D, Worley K, Rogers J, Silvestri G.

Nature. 2018 Jan 3;553(7686):77-81. doi: 10.1038/nature25140.

22.

Exploiting the human peptidome for novel antimicrobial and anticancer agents.

Bosso M, Ständker L, Kirchhoff F, Münch J.

Bioorg Med Chem. 2018 Jun 1;26(10):2719-2726. doi: 10.1016/j.bmc.2017.10.038. Epub 2017 Oct 31. Review.

PMID:
29122440
23.

Current technical approaches to brain energy metabolism.

Barros LF, Bolaños JP, Bonvento G, Bouzier-Sore AK, Brown A, Hirrlinger J, Kasparov S, Kirchhoff F, Murphy AN, Pellerin L, Robinson MB, Weber B.

Glia. 2018 Jun;66(6):1138-1159. doi: 10.1002/glia.23248. Epub 2017 Nov 7. Review.

PMID:
29110344
24.

Molecular Control of HIV and SIV Latency.

Darcis G, Van Driessche B, Bouchat S, Kirchhoff F, Van Lint C.

Curr Top Microbiol Immunol. 2018;417:1-22. doi: 10.1007/82_2017_74.

PMID:
29071474
25.

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals.

Mwimanzi F, Toyoda M, Mahiti M, Mann JK, Martin JN, Bangsberg D, Brockman MA, Goulder P, Kirchhoff F, Brumme ZL, Ndung'u T, Ueno T.

J Virol. 2017 Dec 14;92(1). pii: e01409-17. doi: 10.1128/JVI.01409-17. Print 2018 Jan 1.

26.

Analysis of Functional NMDA Receptors in Astrocytes.

Kirchhoff F.

Methods Mol Biol. 2017;1677:241-251. doi: 10.1007/978-1-4939-7321-7_13.

PMID:
28986877
27.

Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways.

Schwarz Y, Zhao N, Kirchhoff F, Bruns D.

Nat Neurosci. 2017 Nov;20(11):1529-1539. doi: 10.1038/nn.4647. Epub 2017 Sep 25.

PMID:
28945220
28.

Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.

Manrique S, Sauter D, Horenkamp FA, Lülf S, Yu H, Hotter D, Anand K, Kirchhoff F, Geyer M.

Nat Commun. 2017 Sep 5;8(1):442. doi: 10.1038/s41467-017-00481-z.

29.

Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation.

Hotter D, Krabbe T, Reith E, Gawanbacht A, Rahm N, Ayouba A, Van Driessche B, Van Lint C, Peeters M, Kirchhoff F, Sauter D.

PLoS Pathog. 2017 Aug 31;13(8):e1006598. doi: 10.1371/journal.ppat.1006598. eCollection 2017 Aug.

30.

HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells.

Körner C, Simoneau CR, Schommers P, Granoff M, Ziegler M, Hölzemer A, Lunemann S, Chukwukelu J, Corleis B, Naranbhai V, Kwon DS, Scully EP, Jost S, Kirchhoff F, Carrington M, Altfeld M.

Cell Host Microbe. 2017 Jul 12;22(1):111-119.e4. doi: 10.1016/j.chom.2017.06.008.

31.

The Role of the Oligodendrocyte Lineage in Acute Brain Trauma.

Scheller A, Bai X, Kirchhoff F.

Neurochem Res. 2017 Sep;42(9):2479-2489. doi: 10.1007/s11064-017-2343-4. Epub 2017 Jul 12. Review.

PMID:
28702713
32.

Semen amyloids participate in spermatozoa selection and clearance.

Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC.

Elife. 2017 Jun 27;6. pii: e24888. doi: 10.7554/eLife.24888.

33.

TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo.

Belkacemi T, Niermann A, Hofmann L, Wissenbach U, Birnbaumer L, Leidinger P, Backes C, Meese E, Keller A, Bai X, Scheller A, Kirchhoff F, Philipp SE, Weissgerber P, Flockerzi V, Beck A.

Glia. 2017 Sep;65(9):1535-1549. doi: 10.1002/glia.23180. Epub 2017 Jun 21.

34.

Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.

Guidi N, Sacma M, Ständker L, Soller K, Marka G, Eiwen K, Weiss JM, Kirchhoff F, Weil T, Cancelas JA, Florian MC, Geiger H.

EMBO J. 2017 May 15;36(10):1463. doi: 10.15252/embj.201796968. No abstract available.

35.

Pelvic ring fractures in the elderly now and then - a pelvic registry study.

Rollmann MF, Herath SC, Kirchhoff F, Braun BJ, Holstein JH, Pohlemann T, Menger MD, Histing T.

Arch Gerontol Geriatr. 2017 Jul;71:83-88. doi: 10.1016/j.archger.2017.03.007. Epub 2017 Mar 19.

PMID:
28384504
36.

Enrichment and isolation of neurons from adult mouse brain for ex vivo analysis.

Berl S, Karram K, Scheller A, Jungblut M, Kirchhoff F, Waisman A.

J Neurosci Methods. 2017 May 1;283:15-22. doi: 10.1016/j.jneumeth.2017.03.015. Epub 2017 Mar 21.

PMID:
28336359
37.

BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity.

Richard J, Prévost J, von Bredow B, Ding S, Brassard N, Medjahed H, Coutu M, Melillo B, Bibollet-Ruche F, Hahn BH, Kaufmann DE, Smith AB 3rd, Sodroski J, Sauter D, Kirchhoff F, Gee K, Neil SJ, Evans DT, Finzi A.

J Virol. 2017 May 12;91(11). pii: e00219-17. doi: 10.1128/JVI.00219-17. Print 2017 Jun 1.

38.

Generation and Characterization of Virus-Enhancing Peptide Nanofibrils Functionalized with Fluorescent Labels.

Rode S, Hayn M, Röcker A, Sieste S, Lamla M, Markx D, Meier C, Kirchhoff F, Walther P, Fändrich M, Weil T, Münch J.

Bioconjug Chem. 2017 Apr 19;28(4):1260-1270. doi: 10.1021/acs.bioconjchem.7b00079. Epub 2017 Mar 31.

PMID:
28300392
39.

Primate Lentiviruses Modulate NF-κB Activity by Multiple Mechanisms to Fine-Tune Viral and Cellular Gene Expression.

Heusinger E, Kirchhoff F.

Front Microbiol. 2017 Feb 14;8:198. doi: 10.3389/fmicb.2017.00198. eCollection 2017. Review.

40.

Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.

Guidi N, Sacma M, Ständker L, Soller K, Marka G, Eiwen K, Weiss JM, Kirchhoff F, Weil T, Cancelas JA, Florian MC, Geiger H.

EMBO J. 2017 Apr 3;36(7):840-853. doi: 10.15252/embj.201694969. Epub 2017 Mar 2. Erratum in: EMBO J. 2017 May 15;36(10 ):1463.

41.

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.

Jønsson KL, Laustsen A, Krapp C, Skipper KA, Thavachelvam K, Hotter D, Egedal JH, Kjolby M, Mohammadi P, Prabakaran T, Sørensen LK, Sun C, Jensen SB, Holm CK, Lebbink RJ, Johannsen M, Nyegaard M, Mikkelsen JG, Kirchhoff F, Paludan SR, Jakobsen MR.

Nat Commun. 2017 Feb 10;8:14391. doi: 10.1038/ncomms14391.

42.

Efficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain.

Mack K, Starz K, Sauter D, Langer S, Bibollet-Ruche F, Learn GH, Stürzel CM, Leoz M, Plantier JC, Geyer M, Hahn BH, Kirchhoff F.

J Virol. 2017 Feb 28;91(6). pii: e02177-16. doi: 10.1128/JVI.02177-16. Print 2017 Mar 15.

43.

Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks.

Perea G, Gómez R, Mederos S, Covelo A, Ballesteros JJ, Schlosser L, Hernández-Vivanco A, Martín-Fernández M, Quintana R, Rayan A, Díez A, Fuenzalida M, Agarwal A, Bergles DE, Bettler B, Manahan-Vaughan D, Martín ED, Kirchhoff F, Araque A.

Elife. 2016 Dec 24;5. pii: e20362. doi: 10.7554/eLife.20362.

44.

Differential Control of BST2 Restriction and Plasmacytoid Dendritic Cell Antiviral Response by Antagonists Encoded by HIV-1 Group M and O Strains.

Bego MG, Cong L, Mack K, Kirchhoff F, Cohen ÉA.

J Virol. 2016 Oct 28;90(22):10236-10246. Print 2016 Nov 15.

45.

Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells.

Schneider S, Gruart A, Grade S, Zhang Y, Kröger S, Kirchhoff F, Eichele G, Delgado García JM, Dimou L.

Glia. 2016 Dec;64(12):2201-2218. doi: 10.1002/glia.23055. Epub 2016 Sep 12.

PMID:
27615452
46.

IFITMs: Important Factors In Trans-Mission of HIV-1.

Sauter D, Kirchhoff F.

Cell Host Microbe. 2016 Oct 12;20(4):407-408. doi: 10.1016/j.chom.2016.09.009.

47.

HIV Triggers a cGAS-Dependent, Vpu- and Vpr-Regulated Type I Interferon Response in CD4+ T Cells.

Vermeire J, Roesch F, Sauter D, Rua R, Hotter D, Van Nuffel A, Vanderstraeten H, Naessens E, Iannucci V, Landi A, Witkowski W, Baeyens A, Kirchhoff F, Verhasselt B.

Cell Rep. 2016 Oct 4;17(2):413-424. doi: 10.1016/j.celrep.2016.09.023.

48.

The Potency of Nef-Mediated SERINC5 Antagonism Correlates with the Prevalence of Primate Lentiviruses in the Wild.

Heigele A, Kmiec D, Regensburger K, Langer S, Peiffer L, Stürzel CM, Sauter D, Peeters M, Pizzato M, Learn GH, Hahn BH, Kirchhoff F.

Cell Host Microbe. 2016 Sep 14;20(3):381-391. doi: 10.1016/j.chom.2016.08.004.

49.

Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance.

Kmiec D, Iyer SS, Stürzel CM, Sauter D, Hahn BH, Kirchhoff F.

MBio. 2016 Aug 16;7(4). pii: e00934-16. doi: 10.1128/mBio.00934-16.

50.

Phenotype and distribution pattern of nestin-GFP-expressing cells in murine myenteric plexus.

Grundmann D, Markwart F, Scheller A, Kirchhoff F, Schäfer KH.

Cell Tissue Res. 2016 Dec;366(3):573-586. Epub 2016 Aug 13.

PMID:
27519533

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