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Items: 1 to 50 of 365

1.

Conditional Deletion of LRP1 Leads to Progressive Loss of Recombined NG2-Expressing Oligodendrocyte Precursor Cells in a Novel Mouse Model.

Schäfer I, Kaisler J, Scheller A, Kirchhoff F, Haghikia A, Faissner A.

Cells. 2019 Nov 30;8(12). pii: E1550. doi: 10.3390/cells8121550.

PMID:
31801252
2.

Sublamina-specific organization of the blood brain barrier in the mouse olfactory nerve layer.

Beiersdorfer A, Wolburg H, Grawe J, Scheller A, Kirchhoff F, Lohr C.

Glia. 2019 Nov 7. doi: 10.1002/glia.23744. [Epub ahead of print]

PMID:
31696993
3.

Structural Basis for Tetherin Antagonism as a Barrier to Zoonotic Lentiviral Transmission.

Buffalo CZ, Stürzel CM, Heusinger E, Kmiec D, Kirchhoff F, Hurley JH, Ren X.

Cell Host Microbe. 2019 Sep 11;26(3):359-368.e8. doi: 10.1016/j.chom.2019.08.002. Epub 2019 Aug 22.

PMID:
31447307
4.

Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques.

Abdulhaqq SA, Martinez M, Kang G, Rodriguez IV, Nichols SM, Beaumont D, Joseph J, Azzoni L, Yin X, Wise M, Weiner D, Liu Q, Foulkes A, Münch J, Kirchhoff F, Coutifaris C, Tomaras GD, Sariol C, Marx PA, Li Q, Kraiselburd EN, Montaner LJ.

Nat Commun. 2019 Aug 21;10(1):3753. doi: 10.1038/s41467-019-11814-5.

5.

A trip down memory lane with Retrovirology.

Benkirane M, Berkhout B, Borrow P, Fassati A, Fujii M, Garcia-Martinez JV, Margolis D, Nijhuis M, Parent L, Strebel K, Venter F, Kirchhoff F, Lever A, Ross S, Mak J.

Retrovirology. 2019 Aug 21;16(1):22. doi: 10.1186/s12977-019-0485-y. No abstract available.

6.

Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface Expression.

van Stigt Thans T, Akko JI, Niehrs A, Garcia-Beltran WF, Richert L, Stürzel CM, Ford CT, Li H, Ochsenbauer C, Kappes JC, Hahn BH, Kirchhoff F, Martrus G, Sauter D, Altfeld M, Hölzemer A.

J Virol. 2019 Sep 30;93(20). pii: e00719-19. doi: 10.1128/JVI.00719-19. Print 2019 Oct 15.

PMID:
31375574
7.

Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment.

Smith N, Rodero MP, Bekaddour N, Bondet V, Ruiz-Blanco YB, Harms M, Mayer B, Bader-Meunier B, Quartier P, Bodemer C, Baudouin V, Dieudonné Y, Kirchhoff F, Sanchez Garcia E, Charbit B, Leboulanger N, Jahrsdörfer B, Richard Y, Korganow AS, Münch J, Nisole S, Duffy D, Herbeuval JP.

Sci Adv. 2019 Jul 10;5(7):eaav9019. doi: 10.1126/sciadv.aav9019. eCollection 2019 Jul.

8.

Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses.

Prévost J, Pickering S, Mumby MJ, Medjahed H, Gendron-Lepage G, Delgado GG, Dirk BS, Dikeakos JD, Stürzel CM, Sauter D, Kirchhoff F, Bibollet-Ruche F, Hahn BH, Dubé M, Kaufmann DE, Neil SJD, Finzi A, Richard J.

MBio. 2019 Jun 18;10(3). pii: e01113-19. doi: 10.1128/mBio.01113-19.

9.

IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.

Hotter D, Bosso M, Jønsson KL, Krapp C, Stürzel CM, Das A, Littwitz-Salomon E, Berkhout B, Russ A, Wittmann S, Gramberg T, Zheng Y, Martins LJ, Planelles V, Jakobsen MR, Hahn BH, Dittmer U, Sauter D, Kirchhoff F.

Cell Host Microbe. 2019 Jun 12;25(6):858-872.e13. doi: 10.1016/j.chom.2019.05.002. Epub 2019 Jun 4.

PMID:
31175045
10.

N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation.

Yamasoba D, Sato K, Ichinose T, Imamura T, Koepke L, Joas S, Reith E, Hotter D, Misawa N, Akaki K, Uehata T, Mino T, Miyamoto S, Noda T, Yamashita A, Standley DM, Kirchhoff F, Sauter D, Koyanagi Y, Takeuchi O.

Nat Microbiol. 2019 Sep;4(9):1532-1544. doi: 10.1038/s41564-019-0460-3. Epub 2019 May 27.

PMID:
31133753
11.

Role of MHC-I Expression on Spinal Motoneuron Survival and Glial Reactions Following Ventral Root Crush in Mice.

Cartarozzi LP, Perez M, Kirchhoff F, Oliveira ALR.

Cells. 2019 May 21;8(5). pii: E483. doi: 10.3390/cells8050483.

12.

Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins.

Braun E, Hotter D, Koepke L, Zech F, Groß R, Sparrer KMJ, Müller JA, Pfaller CK, Heusinger E, Wombacher R, Sutter K, Dittmer U, Winkler M, Simmons G, Jakobsen MR, Conzelmann KK, Pöhlmann S, Münch J, Fackler OT, Kirchhoff F, Sauter D.

Cell Rep. 2019 May 14;27(7):2092-2104.e10. doi: 10.1016/j.celrep.2019.04.063.

13.

Enteric Glia: S100, GFAP, and Beyond.

Grundmann D, Loris E, Maas-Omlor S, Huang W, Scheller A, Kirchhoff F, Schäfer KH.

Anat Rec (Hoboken). 2019 Aug;302(8):1333-1344. doi: 10.1002/ar.24128. Epub 2019 Apr 29.

PMID:
30951262
14.

Panglial gap junctions between astrocytes and olfactory ensheathing cells mediate transmission of Ca2+ transients and neurovascular coupling.

Beiersdorfer A, Scheller A, Kirchhoff F, Lohr C.

Glia. 2019 Jul;67(7):1385-1400. doi: 10.1002/glia.23613. Epub 2019 Mar 18.

PMID:
30883940
15.

Sex hormones modulate pathogenic processes in experimental traumatic brain injury.

Gölz C, Kirchhoff FP, Westerhorstmann J, Schmidt M, Hirnet T, Rune GM, Bender RA, Schäfer MKE.

J Neurochem. 2019 Jul;150(2):173-187. doi: 10.1111/jnc.14678. Epub 2019 Feb 20.

PMID:
30790293
16.

Early embryonic NG2 glia are exclusively gliogenic and do not generate neurons in the brain.

Huang W, Guo Q, Bai X, Scheller A, Kirchhoff F.

Glia. 2019 Jun;67(6):1094-1103. doi: 10.1002/glia.23590. Epub 2019 Feb 6.

PMID:
30724411
17.

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses.

Langer S, Hammer C, Hopfensperger K, Klein L, Hotter D, De Jesus PD, Herbert KM, Pache L, Smith N, van der Merwe JA, Chanda SK, Fellay J, Kirchhoff F, Sauter D.

Elife. 2019 Feb 5;8. pii: e41930. doi: 10.7554/eLife.41930.

18.

Key Viral Adaptations Preceding the AIDS Pandemic.

Sauter D, Kirchhoff F.

Cell Host Microbe. 2019 Jan 9;25(1):27-38. doi: 10.1016/j.chom.2018.12.002. Review.

PMID:
30629915
19.

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments.

Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet JP, Bezzi P.

Mol Psychiatry. 2018 Aug 20. doi: 10.1038/s41380-018-0226-y. [Epub ahead of print]

20.

SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.

Kmiec D, Akbil B, Ananth S, Hotter D, Sparrer KMJ, Stürzel CM, Trautz B, Ayouba A, Peeters M, Yao Z, Stagljar I, Passos V, Zillinger T, Goffinet C, Sauter D, Fackler OT, Kirchhoff F.

PLoS Pathog. 2018 Aug 20;14(8):e1007269. doi: 10.1371/journal.ppat.1007269. eCollection 2018 Aug.

21.

HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.

Morris KL, Buffalo CZ, Stürzel CM, Heusinger E, Kirchhoff F, Ren X, Hurley JH.

Cell. 2018 Jul 26;174(3):659-671.e14. doi: 10.1016/j.cell.2018.07.004.

22.

Successful HeartMate 3 implantation in isolated right heart failure-first in man experience of right heart configuration.

Ricklefs M, Hanke JS, Dogan G, Chatterjee A, Feldmann C, Deniz E, Korte W, Kirchhoff F, Haverich A, Schmitto JD.

J Thorac Dis. 2018 Jun;10(Suppl 15):S1834-S1837. doi: 10.21037/jtd.2018.05.35. No abstract available.

23.

Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons.

Katz E, Stoler O, Scheller A, Khrapunsky Y, Goebbels S, Kirchhoff F, Gutnick MJ, Wolf F, Fleidervish IA.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7184-E7192. doi: 10.1073/pnas.1720493115. Epub 2018 Jul 10.

24.

Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2.

Heusinger E, Deppe K, Sette P, Krapp C, Kmiec D, Kluge SF, Marx PA, Apetrei C, Kirchhoff F, Sauter D.

J Virol. 2018 Aug 29;92(18). pii: e00276-18. doi: 10.1128/JVI.00276-18. Print 2018 Sep 15.

25.

Comparison of different cytotoxicity assays for in vitro evaluation of mesoporous silica nanoparticles.

Braun K, Stürzel CM, Biskupek J, Kaiser U, Kirchhoff F, Lindén M.

Toxicol In Vitro. 2018 Oct;52:214-221. doi: 10.1016/j.tiv.2018.06.019. Epub 2018 Jun 22.

PMID:
29940343
26.

Reduced Susceptibility to VIRIP-Based HIV-1 Entry Inhibitors Has a High Genetic Barrier and Severe Fitness Costs.

Müller JA, Glöckle A, Gawanbacht A, Geyer M, Münch J, Kirchhoff F.

J Virol. 2018 Aug 16;92(17). pii: e00733-18. doi: 10.1128/JVI.00733-18. Print 2018 Sep 1.

27.

Wearable Cardioverter-Defibrillators following Cardiac Surgery-A Single-Center Experience.

Heimeshoff J, Merz C, Ricklefs M, Kirchhoff F, Haverich A, Bara C, Kühn C.

Thorac Cardiovasc Surg. 2019 Mar;67(2):92-97. doi: 10.1055/s-0038-1660802. Epub 2018 Jun 20.

PMID:
29925094
28.

During Development NG2 Glial Cells of the Spinal Cord are Restricted to the Oligodendrocyte Lineage, but Generate Astrocytes upon Acute Injury.

Huang W, Bai X, Stopper L, Catalin B, Cartarozzi LP, Scheller A, Kirchhoff F.

Neuroscience. 2018 Aug 10;385:154-165. doi: 10.1016/j.neuroscience.2018.06.015. Epub 2018 Jun 18.

PMID:
29913244
29.

The Antiviral Activity of the Cellular Glycoprotein LGALS3BP/90K Is Species Specific.

Lodermeyer V, Ssebyatika G, Passos V, Ponnurangam A, Malassa A, Ewald E, Stürzel CM, Kirchhoff F, Rotger M, Falk CS, Telenti A, Krey T, Goffinet C.

J Virol. 2018 Jun 29;92(14). pii: e00226-18. doi: 10.1128/JVI.00226-18. Print 2018 Jul 15.

30.

Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia.

Jahn HM, Kasakow CV, Helfer A, Michely J, Verkhratsky A, Maurer HH, Scheller A, Kirchhoff F.

Sci Rep. 2018 Apr 12;8(1):5913. doi: 10.1038/s41598-018-24085-9.

31.

Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.

Joas S, Parrish EH, Gnanadurai CW, Lump E, Stürzel CM, Parrish NF, Learn GH, Sauermann U, Neumann B, Rensing KM, Fuchs D, Billingsley JM, Bosinger SE, Silvestri G, Apetrei C, Huot N, Garcia-Tellez T, Müller-Trutwin M, Hotter D, Sauter D, Stahl-Hennig C, Hahn BH, Kirchhoff F.

Nat Commun. 2018 Apr 10;9(1):1371. doi: 10.1038/s41467-018-03762-3.

32.

Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses.

Richard J, Prévost J, Baxter AE, von Bredow B, Ding S, Medjahed H, Delgado GG, Brassard N, Stürzel CM, Kirchhoff F, Hahn BH, Parsons MS, Kaufmann DE, Evans DT, Finzi A.

MBio. 2018 Mar 20;9(2). pii: e00358-18. doi: 10.1128/mBio.00358-18.

33.

Multilayered and versatile inhibition of cellular antiviral factors by HIV and SIV accessory proteins.

Sauter D, Kirchhoff F.

Cytokine Growth Factor Rev. 2018 Apr;40:3-12. doi: 10.1016/j.cytogfr.2018.02.005. Epub 2018 Feb 23. Review.

PMID:
29526437
34.

Fibroblast growth factor 23 is induced by an activated renin-angiotensin-aldosterone system in cardiac myocytes and promotes the pro-fibrotic crosstalk between cardiac myocytes and fibroblasts.

Leifheit-Nestler M, Kirchhoff F, Nespor J, Richter B, Soetje B, Klintschar M, Heineke J, Haffner D.

Nephrol Dial Transplant. 2018 Oct 1;33(10):1722-1734. doi: 10.1093/ndt/gfy006.

PMID:
29425341
35.

In vivo two-photon imaging of motoneurons and adjacent glia in the ventral spinal cord.

Cartarozzi LP, Rieder P, Bai X, Scheller A, Oliveira ALR, Kirchhoff F.

J Neurosci Methods. 2018 Apr 1;299:8-15. doi: 10.1016/j.jneumeth.2018.01.005. Epub 2018 Feb 3.

PMID:
29408351
36.

Interferons and beyond: Induction of antiretroviral restriction factors.

Hotter D, Kirchhoff F.

J Leukoc Biol. 2018 Mar;103(3):465-477. doi: 10.1002/JLB.3MR0717-307R. Epub 2017 Dec 15. Review.

PMID:
29345347
37.

Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo.

Yamada E, Nakaoka S, Klein L, Reith E, Langer S, Hopfensperger K, Iwami S, Schreiber G, Kirchhoff F, Koyanagi Y, Sauter D, Sato K.

Cell Host Microbe. 2018 Jan 10;23(1):110-120.e7. doi: 10.1016/j.chom.2017.12.009.

38.

Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host.

Palesch D, Bosinger SE, Tharp GK, Vanderford TH, Paiardini M, Chahroudi A, Johnson ZP, Kirchhoff F, Hahn BH, Norgren RB, Patel NB, Sodora DL, Dawoud RA, Stewart CB, Seepo SM, Harris RA, Liu Y, Raveendran M, Han Y, English A, Thomas GWC, Hahn MW, Pipes L, Mason CE, Muzny DM, Gibbs RA, Sauter D, Worley K, Rogers J, Silvestri G.

Nature. 2018 Jan 3;553(7686):77-81. doi: 10.1038/nature25140.

39.

Exploiting the human peptidome for novel antimicrobial and anticancer agents.

Bosso M, Ständker L, Kirchhoff F, Münch J.

Bioorg Med Chem. 2018 Jun 1;26(10):2719-2726. doi: 10.1016/j.bmc.2017.10.038. Epub 2017 Oct 31. Review.

PMID:
29122440
40.

Current technical approaches to brain energy metabolism.

Barros LF, Bolaños JP, Bonvento G, Bouzier-Sore AK, Brown A, Hirrlinger J, Kasparov S, Kirchhoff F, Murphy AN, Pellerin L, Robinson MB, Weber B.

Glia. 2018 Jun;66(6):1138-1159. doi: 10.1002/glia.23248. Epub 2017 Nov 7. Review.

41.

Molecular Control of HIV and SIV Latency.

Darcis G, Van Driessche B, Bouchat S, Kirchhoff F, Van Lint C.

Curr Top Microbiol Immunol. 2018;417:1-22. doi: 10.1007/82_2017_74. Review.

PMID:
29071474
42.

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals.

Mwimanzi F, Toyoda M, Mahiti M, Mann JK, Martin JN, Bangsberg D, Brockman MA, Goulder P, Kirchhoff F, Brumme ZL, Ndung'u T, Ueno T.

J Virol. 2017 Dec 14;92(1). pii: e01409-17. doi: 10.1128/JVI.01409-17. Print 2018 Jan 1.

43.

Analysis of Functional NMDA Receptors in Astrocytes.

Kirchhoff F.

Methods Mol Biol. 2017;1677:241-251. doi: 10.1007/978-1-4939-7321-7_13.

PMID:
28986877
44.

Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways.

Schwarz Y, Zhao N, Kirchhoff F, Bruns D.

Nat Neurosci. 2017 Nov;20(11):1529-1539. doi: 10.1038/nn.4647. Epub 2017 Sep 25.

PMID:
28945220
45.

Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.

Manrique S, Sauter D, Horenkamp FA, Lülf S, Yu H, Hotter D, Anand K, Kirchhoff F, Geyer M.

Nat Commun. 2017 Sep 5;8(1):442. doi: 10.1038/s41467-017-00481-z.

46.

Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation.

Hotter D, Krabbe T, Reith E, Gawanbacht A, Rahm N, Ayouba A, Van Driessche B, Van Lint C, Peeters M, Kirchhoff F, Sauter D.

PLoS Pathog. 2017 Aug 31;13(8):e1006598. doi: 10.1371/journal.ppat.1006598. eCollection 2017 Aug.

47.

HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells.

Körner C, Simoneau CR, Schommers P, Granoff M, Ziegler M, Hölzemer A, Lunemann S, Chukwukelu J, Corleis B, Naranbhai V, Kwon DS, Scully EP, Jost S, Kirchhoff F, Carrington M, Altfeld M.

Cell Host Microbe. 2017 Jul 12;22(1):111-119.e4. doi: 10.1016/j.chom.2017.06.008.

48.

The Role of the Oligodendrocyte Lineage in Acute Brain Trauma.

Scheller A, Bai X, Kirchhoff F.

Neurochem Res. 2017 Sep;42(9):2479-2489. doi: 10.1007/s11064-017-2343-4. Epub 2017 Jul 12. Review.

PMID:
28702713
49.

Semen amyloids participate in spermatozoa selection and clearance.

Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC.

Elife. 2017 Jun 27;6. pii: e24888. doi: 10.7554/eLife.24888.

50.

TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo.

Belkacemi T, Niermann A, Hofmann L, Wissenbach U, Birnbaumer L, Leidinger P, Backes C, Meese E, Keller A, Bai X, Scheller A, Kirchhoff F, Philipp SE, Weissgerber P, Flockerzi V, Beck A.

Glia. 2017 Sep;65(9):1535-1549. doi: 10.1002/glia.23180. Epub 2017 Jun 21.

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