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Items: 13


A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis.

Parafati M, Kirby RJ, Khorasanizadeh S, Rastinejad F, Malany S.

Dis Model Mech. 2018 Sep 25;11(9). pii: dmm033530. doi: 10.1242/dmm.033530.


Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress.

Kirby RJ, Divlianska DB, Whig K, Bryan N, Morfa CJ, Koo A, Nguyen KH, Maloney P, Peddibhotla S, Sessions EH, Hershberger PM, Smith LH, Malany S.

J Pharmacol Exp Ther. 2018 Jan;364(1):87-96. doi: 10.1124/jpet.117.243717. Epub 2017 Nov 3. Erratum in: J Pharmacol Exp Ther. 2018 Feb;364(2):179.


Assessment of drug-induced arrhythmic risk using limit cycle and autocorrelation analysis of human iPSC-cardiomyocyte contractility.

Kirby RJ, Qi F, Phatak S, Smith LH, Malany S.

Toxicol Appl Pharmacol. 2016 Aug 15;305:250-258. doi: 10.1016/j.taap.2016.06.025. Epub 2016 Jun 23.


Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface.

Fells JI, Lee SC, Fujiwara Y, Norman DD, Lim KG, Tsukahara R, Liu J, Patil R, Miller DD, Kirby RJ, Nelson S, Seibel W, Papoian R, Parrill AL, Baker DL, Bittman R, Tigyi G.

Mol Pharmacol. 2013 Sep;84(3):415-24. doi: 10.1124/mol.113.087080. Epub 2013 Jun 21.


Development of a small-molecule screening method for inhibitors of cellular response to myostatin and activin A.

Cash JN, Angerman EB, Kirby RJ, Merck L, Seibel WL, Wortman MD, Papoian R, Nelson S, Thompson TB.

J Biomol Screen. 2013 Aug;18(7):837-44. doi: 10.1177/1087057113482585. Epub 2013 Mar 29.


Dynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney.

Kirby RJ, Jin Y, Fu J, Cubillos J, Swertfeger D, Arend LJ.

Am J Physiol Renal Physiol. 2009 Mar;296(3):F634-41. doi: 10.1152/ajprenal.90232.2008. Epub 2008 Dec 10.


The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals.

Law CO, Kirby RJ, Aghamohammadzadeh S, Furley AJ.

Development. 2008 Aug;135(14):2361-71. doi: 10.1242/dev.009019. Epub 2008 Jun 11.


Group 1B phospholipase A2-mediated lysophospholipid absorption directly contributes to postprandial hyperglycemia.

Labonté ED, Kirby RJ, Schildmeyer NM, Cannon AM, Huggins KW, Hui DY.

Diabetes. 2006 Apr;55(4):935-41.


Electrocardiographic parameters of normal alpacas (Lama pacos).

Ferasin L, Ogden DM, Davies SJ, Kirby RJ, D'Alterio GL.

Vet Rec. 2005 Sep 17;157(12):341-3.


Rate of gastric emptying influences dietary cholesterol absorption efficiency in selected inbred strains of mice.

Kirby RJ, Howles PN, Hui DY.

J Lipid Res. 2004 Jan;45(1):89-98. Epub 2003 Oct 16.


Drosophila homolog of the myotonic dystrophy-associated gene, SIX5, is required for muscle and gonad development.

Kirby RJ, Hamilton GM, Finnegan DJ, Johnson KJ, Jarman AP.

Curr Biol. 2001 Jul 10;11(13):1044-9.


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