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A chemical genetics screen reveals influence of p38 map kinase and autophagy on phagosome development and intracellular replication of Brucella neotomae in macrophages.

Kang YS, Kirby JE.

Infect Immun. 2019 Jun 3. pii: IAI.00044-19. doi: 10.1128/IAI.00044-19. [Epub ahead of print]


Evaluation of apramycin against spectinomycin-resistant and -susceptible strains of Neisseria gonorrhoeae.

Riedel S, Vijayakumar D, Berg G, Kang AD, Smith KP, Kirby JE.

J Antimicrob Chemother. 2019 Jan 27. doi: 10.1093/jac/dkz012. [Epub ahead of print]


Brucella neotomae Recapitulates Attributes of Zoonotic Human Disease in a Murine Infection Model.

Kang YS, Brown DA, Kirby JE.

Infect Immun. 2018 Dec 19;87(1). pii: e00255-18. doi: 10.1128/IAI.00255-18. Print 2019 Jan.


Synergistic Activity of Colistin-Containing Combinations against Colistin-Resistant Enterobacteriaceae.

Brennan-Krohn T, Pironti A, Kirby JE.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e00873-18. doi: 10.1128/AAC.00873-18. Print 2018 Oct.


Evaluation of apramycin activity against methicillin-resistant, methicillin-sensitive, and vancomycin-intermediate Staphylococcus aureus clinical isolates.

Truelson KA, Brennan-Krohn T, Smith KP, Kirby JE.

Diagn Microbiol Infect Dis. 2018 Oct;92(2):168-171. doi: 10.1016/j.diagmicrobio.2018.05.018. Epub 2018 May 29.


A Rapid, Accurate, Single Molecule Counting Method Detects Clostridium difficile Toxin B in Stool Samples.

Gite S, Archambault D, Cappillino MP, Cunha D, Dorich V, Shatova T, Tempesta A, Walsh B, Walsh JA, Williams A, Kirby JE, Bowers J, Straus D.

Sci Rep. 2018 May 30;8(1):8364. doi: 10.1038/s41598-018-26353-0.


The Inoculum Effect in the Era of Multidrug Resistance: Minor Differences in Inoculum Have Dramatic Effect on MIC Determination.

Smith KP, Kirby JE.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00433-18. doi: 10.1128/AAC.00433-18. Print 2018 Aug.


Efficacy of Apramycin against Multidrug-Resistant Acinetobacter baumannii in the Murine Neutropenic Thigh Model.

Kang AD, Smith KP, Berg AH, Truelson KA, Eliopoulos GM, McCoy C, Kirby JE.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02585-17. doi: 10.1128/AAC.02585-17. Print 2018 Apr.


Automated Interpretation of Blood Culture Gram Stains by Use of a Deep Convolutional Neural Network.

Smith KP, Kang AD, Kirby JE.

J Clin Microbiol. 2018 Feb 22;56(3). pii: e01521-17. doi: 10.1128/JCM.01521-17. Print 2018 Mar.


Screening for synergistic activity of antimicrobial combinations against carbapenem-resistant Enterobacteriaceae using inkjet printer-based technology.

Brennan-Krohn T, Truelson KA, Smith KP, Kirby JE.

J Antimicrob Chemother. 2017 Oct 1;72(10):2775-2781. doi: 10.1093/jac/dkx241.


Development of MAST: A Microscopy-Based Antimicrobial Susceptibility Testing Platform.

Smith KP, Richmond DL, Brennan-Krohn T, Elliott HL, Kirby JE.

SLAS Technol. 2017 Dec;22(6):662-674. doi: 10.1177/2472630317727721. Epub 2017 Aug 24.


Arthroconidia in lung tissue: an unusual histopathological finding in pulmonary coccidioidomycosis.

Brennan-Krohn T, Yoon E, Nishino M, Kirby JE, Riedel S.

Hum Pathol. 2018 Jan;71:55-59. doi: 10.1016/j.humpath.2017.07.013. Epub 2017 Aug 1.


Activity of minocycline against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae clinical isolates, with comparison to doxycycline and tigecycline.

Chen A, Smith KP, Whitfield BA, Zucchi PC, Lasco TM, Bias TE, Kirby JE, Hirsch EB.

Diagn Microbiol Infect Dis. 2017 Aug;88(4):365-367. doi: 10.1016/j.diagmicrobio.2017.05.004. Epub 2017 May 11.


The Poisoned Well: Enhancing the Predictive Value of Antimicrobial Susceptibility Testing in the Era of Multidrug Resistance.

Brennan-Krohn T, Smith KP, Kirby JE.

J Clin Microbiol. 2017 Aug;55(8):2304-2308. doi: 10.1128/JCM.00511-17. Epub 2017 May 3.


Invitro Apramycin Activity against multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.

Kang AD, Smith KP, Eliopoulos GM, Berg AH, McCoy C, Kirby JE.

Diagn Microbiol Infect Dis. 2017 Jun;88(2):188-191. doi: 10.1016/j.diagmicrobio.2017.03.006. Epub 2017 Mar 16.


Promotion and Rescue of Intracellular Brucella neotomae Replication during Coinfection with Legionella pneumophila.

Kang YS, Kirby JE.

Infect Immun. 2017 Apr 21;85(5). pii: e00991-16. doi: 10.1128/IAI.00991-16. Print 2017 May.


Answer to February 2017 Photo Quiz.

Bryan AW Jr, Qian Q, Kirby JE.

J Clin Microbiol. 2017 Feb;55(2):660-661. doi: 10.1128/JCM.00194-15. No abstract available.


Photo Quiz: A Man with Fever and Headache.

Bryan AW Jr, Qian Q, Kirby JE.

J Clin Microbiol. 2017 Feb;55(2):351. doi: 10.1128/JCM.00193-15. No abstract available.


Investigation of a Candida guilliermondii Pseudo-outbreak Reveals a Novel Source of Laboratory Contamination.

Kirby JE, Branch-Elliman W, LaSalvia MT, Longhi L, MacKechnie M, Urman G, Baldini LM, Muriel FR, Sullivan B, Yassa DS, Gold HS, Wagner TK, Diekema DJ, Wright SB.

J Clin Microbiol. 2017 Apr;55(4):1080-1089. doi: 10.1128/JCM.02336-16. Epub 2017 Jan 18.


Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.

Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA, Wortman JR, Murphy CI, Hanage WP.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1135-1140. doi: 10.1073/pnas.1616248114. Epub 2017 Jan 17.


Improved Accuracy of Cefepime Susceptibility Testing for Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae with an On-Demand Digital Dispensing Method.

Smith KP, Brennan-Krohn T, Weir S, Kirby JE.

J Clin Microbiol. 2017 Feb;55(2):470-478. doi: 10.1128/JCM.02128-16. Epub 2016 Nov 30.


Evaluation of apramycin activity against carbapenem-resistant and -susceptible strains of Enterobacteriaceae.

Smith KP, Kirby JE.

Diagn Microbiol Infect Dis. 2016 Dec;86(4):439-441. doi: 10.1016/j.diagmicrobio.2016.09.002. Epub 2016 Sep 8.


How inkjet printing technology can defeat multidrug-resistant pathogens.

Smith KP, Kirby JE.

Future Microbiol. 2016 Oct;11:1375-1377. Epub 2016 Oct 27. No abstract available.


Fatal purpura fulminans and Waterhouse-Friderichsen syndrome from fulminant Streptococcus pneumoniae sepsis in an asplenic young adult.

Hale AJ, LaSalvia M, Kirby JE, Kimball A, Baden R.

IDCases. 2016 Aug 16;6:1-4. doi: 10.1016/j.idcr.2016.08.004. eCollection 2016.


Female mice lacking Xist RNA show partial dosage compensation and survive to term.

Yang L, Kirby JE, Sunwoo H, Lee JT.

Genes Dev. 2016 Aug 1;30(15):1747-60. doi: 10.1101/gad.281162.116.


Fatal Spontaneous Clostridium bifermentans Necrotizing Endometritis: A Case Report and Literature Review of the Pathogen.

Hale A, Kirby JE, Albrecht M.

Open Forum Infect Dis. 2016 May 12;3(2):ofw095. doi: 10.1093/ofid/ofw095. eCollection 2016 Apr.


Verification of an Automated, Digital Dispensing Platform for At-Will Broth Microdilution-Based Antimicrobial Susceptibility Testing.

Smith KP, Kirby JE.

J Clin Microbiol. 2016 Sep;54(9):2288-93. doi: 10.1128/JCM.00932-16. Epub 2016 Jun 22.


Photo Quiz: A Man with Fever and Cough.

Qian Q, Urman G, Cederroth T, Najarian R, Kirby JE.

J Clin Microbiol. 2016 Apr;54(4):825; discussion 1177. doi: 10.1128/JCM.00851-14. No abstract available.


Susceptibility of Multidrug-Resistant Gram-Negative Urine Isolates to Oral Antibiotics.

Hirsch EB, Zucchi PC, Chen A, Raux BR, Kirby JE, McCoy C, Eliopoulos GM.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):3138-40. doi: 10.1128/AAC.02961-15. Print 2016 May.


Utility of microbiological testing of thoracic lymph nodes sampled by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with mediastinal lymphadenopathy.

Harris RM, Arnaout R, Koziel H, Folch E, Majid A, Kirby JE.

Diagn Microbiol Infect Dis. 2016 Feb;84(2):170-4. doi: 10.1016/j.diagmicrobio.2015.10.013. Epub 2015 Oct 21.


Activity of fosfomycin and comparison of several susceptibility testing methods against contemporary urine isolates.

Hirsch EB, Raux BR, Zucchi PC, Kim Y, McCoy C, Kirby JE, Wright SB, Eliopoulos GM.

Int J Antimicrob Agents. 2015 Dec;46(6):642-7. doi: 10.1016/j.ijantimicag.2015.08.012. Epub 2015 Sep 30.


Continuous positive airway pressure-associated cutaneous amoebiasis in an immunosuppressed patient.

Sells RE, Chen CA, Wong MT, Zimarowski MJ, Kirby JE, Joyce RM, Wu PA.

Br J Dermatol. 2016 Mar;174(3):625-8. doi: 10.1111/bjd.14231. Epub 2016 Jan 5.


High-Throughput Intracellular Antimicrobial Susceptibility Testing of Legionella pneumophila.

Chiaraviglio L, Kirby JE.

Antimicrob Agents Chemother. 2015 Dec;59(12):7517-29. doi: 10.1128/AAC.01248-15. Epub 2015 Sep 21.


Pathological rib fracture and soft tissue mass simulating malignancy--Cryptococcus, an unsuspected culprit.

Harris RM, Stillman IE, Goldsmith JD, Qian Q, Kirby JE.

Diagn Microbiol Infect Dis. 2015 Mar;81(3):189-91. doi: 10.1016/j.diagmicrobio.2014.10.010. Epub 2014 Oct 31.


Evaluation of the Hologic gen-probe PANTHER, APTIMA Combo 2 assay in a tertiary care teaching hospital.

Cheng A, Kirby JE.

Am J Clin Pathol. 2014 Mar;141(3):397-403. doi: 10.1309/AJCPFQ25SQVZAWHZ.


Rapid identification of Staphylococcus aureus directly from Bactec blood culture broth by the BinaxNOW S. aureus test.

Qian Q, Eichelberger K, Kirby JE.

J Clin Microbiol. 2014 Jan;52(1):319-20. doi: 10.1128/JCM.02291-13. Epub 2013 Oct 23.


Xist RNA is a potent suppressor of hematologic cancer in mice.

Yildirim E, Kirby JE, Brown DE, Mercier FE, Sadreyev RI, Scadden DT, Lee JT.

Cell. 2013 Feb 14;152(4):727-42. doi: 10.1016/j.cell.2013.01.034.


Mechanisms of TBI and visual consequences in military and veteran populations.

Goodrich GL, Flyg HM, Kirby JE, Chang CY, Martinsen GL.

Optom Vis Sci. 2013 Feb;90(2):105-12. doi: 10.1097/OPX.0b013e31827f15a1.


Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes.

Anguera MC, Sadreyev R, Zhang Z, Szanto A, Payer B, Sheridan SD, Kwok S, Haggarty SJ, Sur M, Alvarez J, Gimelbrant A, Mitalipova M, Kirby JE, Lee JT.

Cell Stem Cell. 2012 Jul 6;11(1):75-90. doi: 10.1016/j.stem.2012.03.008.


Evaluation of the Abbott RealTime CT/NG assay in comparison to the Roche Cobas Amplicor CT/NG assay.

Cheng A, Qian Q, Kirby JE.

J Clin Microbiol. 2011 Apr;49(4):1294-300. doi: 10.1128/JCM.02595-10. Epub 2011 Feb 16.


An immunocompromised murine model of chronic Bartonella infection.

Chiaraviglio L, Duong S, Brown DA, Birtles RJ, Kirby JE.

Am J Pathol. 2010 Jun;176(6):2753-63. doi: 10.2353/ajpath.2010.090862. Epub 2010 Apr 15.


The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide.

Soscia SJ, Kirby JE, Washicosky KJ, Tucker SM, Ingelsson M, Hyman B, Burton MA, Goldstein LE, Duong S, Tanzi RE, Moir RD.

PLoS One. 2010 Mar 3;5(3):e9505. doi: 10.1371/journal.pone.0009505.


Direct detection of methicillin resistance in Staphylococcus aureus in blood culture broth by use of a penicillin binding protein 2a latex agglutination test.

Qian Q, Venkataraman L, Kirby JE, Gold HS, Yamazumi T.

J Clin Microbiol. 2010 Apr;48(4):1420-1. doi: 10.1128/JCM.01517-09. Epub 2010 Feb 3.


Ruling out novel H1N1 influenza virus infection with direct fluorescent antigen testing.

Pollock NR, Duong S, Cheng A, Han LL, Smole S, Kirby JE.

Clin Infect Dis. 2009 Sep 15;49(6):e66-8. doi: 10.1086/644502.


Effective use of JC virus PCR for diagnosis of progressive multifocal leukoencephalopathy.

Wang Y, Kirby JE, Qian Q.

J Med Microbiol. 2009 Feb;58(Pt 2):253-5. doi: 10.1099/jmm.0.004432-0.


Optimal use of Myco/F lytic and standard BACTEC blood culture bottles for detection of yeast and mycobacteria.

Kirby JE, Delaney M, Qian Q, Gold HS.

Arch Pathol Lab Med. 2009 Jan;133(1):93-6. doi: 10.1043/1543-2165-133.1.93.


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