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Items: 1 to 50 of 135

1.

Independent effects of dietary fat and sucrose content on chondrocyte metabolism and osteoarthritis pathology in mice.

Donovan EL, Lopes EBP, Batushansky A, Kinter M, Griffin TM.

Dis Model Mech. 2018 Jul 16. pii: dmm.034827. doi: 10.1242/dmm.034827. [Epub ahead of print]

2.

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.

Tarantini S, Valcarcel-Ares MN, Yabluchanskiy A, Tucsek Z, Hertelendy P, Kiss T, Gautam T, Zhang XA, Sonntag WE, de Cabo R, Farkas E, Elliott MH, Kinter MT, Deak F, Ungvari Z, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):853-863. doi: 10.1093/gerona/glx177.

PMID:
29905772
3.

Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.

Deepa SS, Pharaoh G, Kinter M, Diaz V, Fok WC, Riddle K, Pulliam D, Hill S, Fischer KE, Soto V, Georgescu C, Wren JD, Viscomi C, Richardson A, Van Remmen H.

Aging Cell. 2018 Apr 25:e12769. doi: 10.1111/acel.12769. [Epub ahead of print]

4.

Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass.

Ahn B, Pharaoh G, Premkumar P, Huseman K, Ranjit R, Kinter M, Szweda L, Kiss T, Fulop G, Tarantini S, Csiszar A, Ungvari Z, Van Remmen H.

Redox Biol. 2018 Jul;17:47-58. doi: 10.1016/j.redox.2018.04.004. Epub 2018 Apr 6. No abstract available.

5.

Coenzyme A-mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice.

Schafer C, Young ZT, Makarewich CA, Elnwasany A, Kinter C, Kinter M, Szweda LI.

J Biol Chem. 2018 May 4;293(18):6915-6924. doi: 10.1074/jbc.RA117.000268. Epub 2018 Mar 14.

PMID:
29540486
6.

Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance.

Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS.

EMBO Rep. 2018 Mar;19(3). pii: e45009. doi: 10.15252/embr.201745009. Epub 2018 Feb 2.

PMID:
29420235
7.

Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes.

Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE.

Mol Metab. 2018 Mar;9:141-155. doi: 10.1016/j.molmet.2018.01.013. Epub 2018 Feb 2.

8.

Cardiac Insulin Signaling Regulates Glycolysis Through Phosphofructokinase 2 Content and Activity.

Bockus LB, Matsuzaki S, Vadvalkar SS, Young ZT, Giorgione JR, Newhardt MF, Kinter M, Humphries KM.

J Am Heart Assoc. 2017 Dec 4;6(12). pii: e007159. doi: 10.1161/JAHA.117.007159.

9.

PPARα is essential for retinal lipid metabolism and neuronal survival.

Pearsall EA, Cheng R, Zhou K, Takahashi Y, Matlock HG, Vadvalkar SS, Shin Y, Fredrick TW, Gantner ML, Meng S, Fu Z, Gong Y, Kinter M, Humphries KM, Szweda LI, Smith LEH, Ma JX.

BMC Biol. 2017 Nov 28;15(1):113. doi: 10.1186/s12915-017-0451-x.

10.

Photoreceptor glucose metabolism determines normal retinal vascular growth.

Fu Z, Löfqvist CA, Liegl R, Wang Z, Sun Y, Gong Y, Liu CH, Meng SS, Burnim SB, Arellano I, Chouinard MT, Duran R, Poblete A, Cho SS, Akula JD, Kinter M, Ley D, Pupp IH, Talukdar S, Hellström A, Smith LE.

EMBO Mol Med. 2018 Jan;10(1):76-90. doi: 10.15252/emmm.201707966.

11.

Functional changes in the neural retina occur in the absence of mitochondrial dysfunction in a rodent model of diabetic retinopathy.

Masser DR, Otalora L, Clark NW, Kinter MT, Elliott MH, Freeman WM.

J Neurochem. 2017 Dec;143(5):595-608. doi: 10.1111/jnc.14216. Epub 2017 Oct 20.

PMID:
28902411
12.

Effect of biomechanical stress on endogenous antioxidant networks in bovine articular cartilage.

Issa R, Boeving M, Kinter M, Griffin TM.

J Orthop Res. 2018 Feb;36(2):760-769. doi: 10.1002/jor.23728. Epub 2017 Oct 17.

PMID:
28892196
13.

A fish oil diet induces mitochondrial uncoupling and mitochondrial unfolded protein response in epididymal white adipose tissue of mice.

Bhaskaran S, Unnikrishnan A, Ranjit R, Qaisar R, Pharaoh G, Matyi S, Kinter M, Deepa SS.

Free Radic Biol Med. 2017 Jul;108:704-714. doi: 10.1016/j.freeradbiomed.2017.04.028. Epub 2017 Apr 26.

PMID:
28455142
14.

Decreased Mitochondrial Pyruvate Transport Activity in the Diabetic Heart: ROLE OF MITOCHONDRIAL PYRUVATE CARRIER 2 (MPC2) ACETYLATION.

Vadvalkar SS, Matsuzaki S, Eyster CA, Giorgione JR, Bockus LB, Kinter CS, Kinter M, Humphries KM.

J Biol Chem. 2017 Mar 17;292(11):4423-4433. doi: 10.1074/jbc.M116.753509. Epub 2017 Feb 1.

15.

Regulation of Pyruvate Dehydrogenase Kinase 4 in the Heart through Degradation by the Lon Protease in Response to Mitochondrial Substrate Availability.

Crewe C, Schafer C, Lee I, Kinter M, Szweda LI.

J Biol Chem. 2017 Jan 6;292(1):305-312. doi: 10.1074/jbc.M116.754127. Epub 2016 Nov 17.

16.

Catalase-dependent H2O2 consumption by cardiac mitochondria and redox-mediated loss in insulin signaling.

Rindler PM, Cacciola A, Kinter M, Szweda LI.

Am J Physiol Heart Circ Physiol. 2016 Nov 1;311(5):H1091-H1096. doi: 10.1152/ajpheart.00066.2016. Epub 2016 Sep 9.

17.

Hypoxia induces heart regeneration in adult mice.

Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA.

Nature. 2017 Jan 12;541(7636):222-227. doi: 10.1038/nature20173. Epub 2016 Oct 31.

PMID:
27798600
18.

Correction: Interaction of G-Protein βγ Complex with Chromatin Modulates GPCR-Dependent Gene Regulation.

Bhatnagar A, Unal H, Jagannathan R, Kaveti S, Duan ZH, Yong S, Vasanji A, Kinter M, Desnoyer R, Karnik SS.

PLoS One. 2016 May 4;11(5):e0155198. doi: 10.1371/journal.pone.0155198. eCollection 2016.

19.

Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis.

Fu Y, Kinter M, Hudson J, Humphries KM, Lane RS, White JR, Hakim M, Pan Y, Verdin E, Griffin TM.

Arthritis Rheumatol. 2016 Aug;68(8):1887-98. doi: 10.1002/art.39618.

20.

Nutrient sensing and utilization: Getting to the heart of metabolic flexibility.

Griffin TM, Humphries KM, Kinter M, Lim HY, Szweda LI.

Biochimie. 2016 May;124:74-83. doi: 10.1016/j.biochi.2015.10.013. Epub 2015 Oct 22. Review.

21.

The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging.

Walsh ME, Bhattacharya A, Sataranatarajan K, Qaisar R, Sloane L, Rahman MM, Kinter M, Van Remmen H.

Aging Cell. 2015 Dec;14(6):957-70. doi: 10.1111/acel.12387. Epub 2015 Aug 20.

22.

Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae.

Meyer RE, Chuong HH, Hild M, Hansen CL, Kinter M, Dawson DS.

Mol Biol Cell. 2015 Sep 1;26(17):2986-3000. doi: 10.1091/mbc.E15-01-0032. Epub 2015 Jul 8.

23.

Lysine Acetylation Activates Mitochondrial Aconitase in the Heart.

Fernandes J, Weddle A, Kinter CS, Humphries KM, Mather T, Szweda LI, Kinter M.

Biochemistry. 2015 Jun 30;54(25):4008-18. doi: 10.1021/acs.biochem.5b00375. Epub 2015 Jun 19.

24.

Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src.

Tsutsui Y, Johnson JM, Demeler B, Kinter MT, Hays FA.

Biochemistry. 2015 Jun 9;54(22):3469-82. doi: 10.1021/acs.biochem.5b00122. Epub 2015 May 26.

PMID:
25961473
25.

Mitochondrial respiration and redox coupling in articular chondrocytes.

Lane RS, Fu Y, Matsuzaki S, Kinter M, Humphries KM, Griffin TM.

Arthritis Res Ther. 2015 Mar 10;17:54. doi: 10.1186/s13075-015-0566-9.

26.

Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction.

Wong KE, Mikus CR, Slentz DH, Seiler SE, DeBalsi KL, Ilkayeva OR, Crain KI, Kinter MT, Kien CL, Stevens RD, Muoio DM.

Diabetes. 2015 May;64(5):1532-43. doi: 10.2337/db14-0827. Epub 2014 Nov 24.

27.

Complement factor H, vitronectin, and opticin are tyrosine-sulfated proteins of the retinal pigment epithelium.

Kanan Y, Siefert JC, Kinter M, Al-Ubaidi MR.

PLoS One. 2014 Aug 19;9(8):e105409. doi: 10.1371/journal.pone.0105409. eCollection 2014.

28.

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.

Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA.

Cell. 2014 Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032. Erratum in: Cell. 2014 May 22;157(5):1243.

29.

Rapid inhibition of pyruvate dehydrogenase: an initiating event in high dietary fat-induced loss of metabolic flexibility in the heart.

Crewe C, Kinter M, Szweda LI.

PLoS One. 2013 Oct 7;8(10):e77280. doi: 10.1371/journal.pone.0077280. eCollection 2013.

30.

An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression.

Wang S, Wen F, Wiley GB, Kinter MT, Gaffney PM.

PLoS Genet. 2013;9(9):e1003750. doi: 10.1371/journal.pgen.1003750. Epub 2013 Sep 5.

31.

Vimentin is a target of PKCβ phosphorylation in MCP-1-activated primary human monocytes.

Thiagarajan PS, Akbasli AC, Kinter MT, Willard B, Cathcart MK.

Inflamm Res. 2013 Nov;62(11):991-1001. doi: 10.1007/s00011-013-0657-5. Epub 2013 Aug 22.

32.

Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria.

Rindler PM, Crewe CL, Fernandes J, Kinter M, Szweda LI.

Am J Physiol Heart Circ Physiol. 2013 Sep 1;305(5):H634-43. doi: 10.1152/ajpheart.00799.2012. Epub 2013 Jun 21. Review.

33.

Glutathionylation of α-ketoglutarate dehydrogenase: the chemical nature and relative susceptibility of the cofactor lipoic acid to modification.

McLain AL, Cormier PJ, Kinter M, Szweda LI.

Free Radic Biol Med. 2013 Aug;61:161-9. doi: 10.1016/j.freeradbiomed.2013.03.020. Epub 2013 Apr 6.

34.

Interaction of G-protein βγ complex with chromatin modulates GPCR-dependent gene regulation.

Bhatnagar A, Unal H, Jagannathan R, Kaveti S, Duan ZH, Yong S, Vasanji A, Kinter M, Desnoyer R, Karnik SS.

PLoS One. 2013;8(1):e52689. doi: 10.1371/journal.pone.0052689. Epub 2013 Jan 9. Erratum in: PLoS One. 2016;11(5):e0155198.

35.

High dietary fat selectively increases catalase expression within cardiac mitochondria.

Rindler PM, Plafker SM, Szweda LI, Kinter M.

J Biol Chem. 2013 Jan 18;288(3):1979-90. doi: 10.1074/jbc.M112.412890. Epub 2012 Nov 30.

36.

A quantitative proteomic profile of the Nrf2-mediated antioxidant response of macrophages to oxidized LDL determined by multiplexed selected reaction monitoring.

Kinter CS, Lundie JM, Patel H, Rindler PM, Szweda LI, Kinter M.

PLoS One. 2012;7(11):e50016. doi: 10.1371/journal.pone.0050016. Epub 2012 Nov 16.

37.

Proteomic and bioinformatic profile of primary human oral epithelial cells.

Ghosh SK, Yohannes E, Bebek G, Weinberg A, Jiang B, Willard B, Chance MR, Kinter MT, McCormick TS.

J Proteome Res. 2012 Nov 2;11(11):5492-502. doi: 10.1021/pr3007254. Epub 2012 Oct 16.

38.

Disulfide bond as a switch for copper-zinc superoxide dismutase activity in asthma.

Ghosh S, Willard B, Comhair SA, Dibello P, Xu W, Shiva S, Aulak KS, Kinter M, Erzurum SC.

Antioxid Redox Signal. 2013 Feb 1;18(4):412-23. doi: 10.1089/ars.2012.4566. Epub 2012 Sep 7.

39.

Methylation of γ-carboxylated Glu (Gla) allows detection by liquid chromatography-mass spectrometry and the identification of Gla residues in the γ-glutamyl carboxylase.

Hallgren KW, Zhang D, Kinter M, Willard B, Berkner KL.

J Proteome Res. 2013 Jun 7;12(6):2365-74. doi: 10.1021/pr3003722. Epub 2013 May 10.

40.

Polycystin-1 regulates STAT activity by a dual mechanism.

Talbot JJ, Shillingford JM, Vasanth S, Doerr N, Mukherjee S, Kinter MT, Watnick T, Weimbs T.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7985-90. doi: 10.1073/pnas.1103816108. Epub 2011 Apr 25.

41.

Tyrosine 656 in topoisomerase IIβ is important for the catalytic activity of the enzyme: Identification based on artifactual +80-Da modification at this site.

Grozav AG, Willard BB, Kozuki T, Chikamori K, Micluta MA, Petrescu AJ, Kinter M, Ganapathi R, Ganapathi MK.

Proteomics. 2011 Mar;11(5):829-42. doi: 10.1002/pmic.201000194. Epub 2011 Jan 31.

42.

Deposition of stearate-oleate rich seed fat in Mangifera indica is mediated by a FatA type acyl-ACP thioesterase.

Bhattacharjee A, Ghosh SK, Neogi K, Aich A, Willard B, Kinter M, Sen SK, Ghosh D, Ghosh S.

Phytochemistry. 2011 Feb;72(2-3):166-77. doi: 10.1016/j.phytochem.2010.11.004. Epub 2010 Dec 2.

PMID:
21130480
43.

AT1 receptor induced alterations in histone H2A reveal novel insights into GPCR control of chromatin remodeling.

Jagannathan R, Kaveti S, Desnoyer RW, Willard B, Kinter M, Karnik SS.

PLoS One. 2010 Sep 3;5(9):e12552. doi: 10.1371/journal.pone.0012552.

44.

Proteomic analysis of pollination-induced corolla senescence in petunia.

Bai S, Willard B, Chapin LJ, Kinter MT, Francis DM, Stead AD, Jones ML.

J Exp Bot. 2010 Feb;61(4):1089-109. doi: 10.1093/jxb/erp373. Epub 2010 Jan 28.

45.

The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia.

DiBello PM, Dayal S, Kaveti S, Zhang D, Kinter M, Lentz SR, Jacobsen DW.

Mol Cell Proteomics. 2010 Mar;9(3):471-85. doi: 10.1074/mcp.M900406-MCP200. Epub 2009 Dec 14.

46.

REH2 RNA helicase in kinetoplastid mitochondria: ribonucleoprotein complexes and essential motifs for unwinding and guide RNA (gRNA) binding.

Hernandez A, Madina BR, Ro K, Wohlschlegel JA, Willard B, Kinter MT, Cruz-Reyes J.

J Biol Chem. 2010 Jan 8;285(2):1220-8. doi: 10.1074/jbc.M109.051862. Epub 2009 Oct 22.

47.

Two-site phosphorylation of EPRS coordinates multimodal regulation of noncanonical translational control activity.

Arif A, Jia J, Mukhopadhyay R, Willard B, Kinter M, Fox PL.

Mol Cell. 2009 Jul 31;35(2):164-80. doi: 10.1016/j.molcel.2009.05.028.

48.

Protein sequencing with tandem mass spectrometry.

Ziady AG, Kinter M.

Methods Mol Biol. 2009;544:325-41. doi: 10.1007/978-1-59745-483-4_21.

PMID:
19488709
49.

Glucose-mediated tyrosine nitration in adipocytes: targets and consequences.

Koeck T, Willard B, Crabb JW, Kinter M, Stuehr DJ, Aulak KS.

Free Radic Biol Med. 2009 Apr 1;46(7):884-92. doi: 10.1016/j.freeradbiomed.2008.12.010. Epub 2008 Dec 24.

50.

Ribosomal S6 kinase 2 directly phosphorylates the 5-hydroxytryptamine 2A (5-HT2A) serotonin receptor, thereby modulating 5-HT2A signaling.

Strachan RT, Sheffler DJ, Willard B, Kinter M, Kiselar JG, Roth BL.

J Biol Chem. 2009 Feb 27;284(9):5557-73. doi: 10.1074/jbc.M805705200. Epub 2008 Dec 22.

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