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Items: 41

1.

Final congenital melanocytic naevi colour is determined by normal skin colour and unaltered by superficial removal techniques: a longitudinal study.

Polubothu S, Kinsler VA.

Br J Dermatol. 2019 May 23. doi: 10.1111/bjd.18149. [Epub ahead of print]

PMID:
31120141
2.

Does the gene matter? Genotype-phenotype and genotype-outcome associations in congenital melanocytic naevi.

Polubothu S, McGuire N, Al-Olabi L, Baird W, Bulstrode N, Chalker J, Josifova D, Lomas D, O'Hara J, Ong J, Rampling D, Stadnik P, Thomas A, Wedgeworth E, Sebire NJ, Kinsler VA.

Br J Dermatol. 2019 May 21. doi: 10.1111/bjd.18106. [Epub ahead of print]

PMID:
31111470
3.

Striking contiguous depigmentation across the lower limbs in piebaldism and its implications for understanding melanocytic migration and development.

Funkhouser CH, Kinsler VA, Frieden IJ.

Pediatr Dermatol. 2019 Jul;36(4):511-513. doi: 10.1111/pde.13831. Epub 2019 Apr 14.

PMID:
30983016
4.

Mosaic abnormalities of the skin: review and guidelines from the European Reference Network for rare skin diseases.

Kinsler VA, Boccara O, Fraitag S, Torrelo A, Vabres P, Diociaiuti A.

Br J Dermatol. 2019 Mar 28. doi: 10.1111/bjd.17924. [Epub ahead of print] Review.

PMID:
30920652
5.

Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.

Al-Olabi L, Polubothu S, Dowsett K, Andrews KA, Stadnik P, Joseph AP, Knox R, Pittman A, Clark G, Baird W, Bulstrode N, Glover M, Gordon K, Hargrave D, Huson SM, Jacques TS, James G, Kondolf H, Kangesu L, Keppler-Noreuil KM, Khan A, Lindhurst MJ, Lipson M, Mansour S, O'Hara J, Mahon C, Mosica A, Moss C, Murthy A, Ong J, Parker VE, Rivière JB, Sapp JC, Sebire NJ, Shah R, Sivakumar B, Thomas A, Virasami A, Waelchli R, Zeng Z, Biesecker LG, Barnacle A, Topf M, Semple RK, Patton EE, Kinsler VA.

J Clin Invest. 2018 Nov 1;128(11):5185. doi: 10.1172/JCI124649. Epub 2018 Nov 1. No abstract available.

6.

Sedation for screening MRI in patients with congenital melanocytic naevi under the age of one is a successful, safe and economical first-line approach.

Plumptre I, Stuart G, Cerullo A, Kinsler VA.

Br J Dermatol. 2019 Mar;180(3):668-669. doi: 10.1111/bjd.17263. Epub 2018 Dec 3. No abstract available.

7.

Uniparental disomy as a mechanism for CERS3-mutated autosomal recessive congenital ichthyosis.

Polubothu S, Glover M, Holder SE, Kinsler VA.

Br J Dermatol. 2018 Nov;179(5):1214-1215. doi: 10.1111/bjd.16999. Epub 2018 Sep 20. No abstract available.

8.

Aggressive melanoma in an infant with congenital melanocytic nevus syndrome and multiple, NRAS and BRAF mutation-negative nodules.

de la Rosa Carrillo D, Vindenes H, Kinsler VA, Rønnestad A, Ringstad G, Müller LO, Tafjord S, Tønseth KA, Kvamme B, Clausen OPF.

Pediatr Dermatol. 2018 Sep;35(5):e281-e285. doi: 10.1111/pde.13595. Epub 2018 Jul 12.

PMID:
29999207
9.

Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.

Al-Olabi L, Polubothu S, Dowsett K, Andrews KA, Stadnik P, Joseph AP, Knox R, Pittman A, Clark G, Baird W, Bulstrode N, Glover M, Gordon K, Hargrave D, Huson SM, Jacques TS, James G, Kondolf H, Kangesu L, Keppler-Noreuil KM, Khan A, Lindhurst MJ, Lipson M, Mansour S, O'Hara J, Mahon C, Mosica A, Moss C, Murthy A, Ong J, Parker VE, Rivière JB, Sapp JC, Sebire NJ, Shah R, Sivakumar B, Thomas A, Virasami A, Waelchli R, Zeng Z, Biesecker LG, Barnacle A, Topf M, Semple RK, Patton EE, Kinsler VA.

J Clin Invest. 2018 Apr 2;128(4):1496-1508. doi: 10.1172/JCI98589. Epub 2018 Mar 12. Erratum in: J Clin Invest. 2018 Nov 1;128(11):5185.

10.

Widespread dynamic and pleiotropic expression of the melanocortin-1-receptor (MC1R) system is conserved across chick, mouse and human embryonic development.

Thomas AC, Heux P, Santos C, Arulvasan W, Solanky N, Carey ME, Gerrelli D, Kinsler VA, Etchevers HC.

Birth Defects Res. 2018 Mar 15;110(5):443-455. doi: 10.1002/bdr2.1183. Epub 2018 Jan 8.

11.

The patterns of birthmarks suggest a novel population of melanocyte precursors arising around the time of gastrulation.

Kinsler VA, Larue L.

Pigment Cell Melanoma Res. 2018 Jan;31(1):95-109. doi: 10.1111/pcmr.12645. Epub 2017 Oct 13.

12.

Atypical dermal melanocytosis: a diagnostic clue in constitutional mismatch repair deficiency syndrome.

Polubothu S, Scott RH, Vabres P, Kinsler VA.

Br J Dermatol. 2017 Nov;177(5):e185-e186. doi: 10.1111/bjd.15532. Epub 2017 Sep 28. Review. No abstract available.

13.

MEK inhibition appears to improve symptom control in primary NRAS-driven CNS melanoma in children.

Kinsler VA, O'Hare P, Jacques T, Hargrave D, Slater O.

Br J Cancer. 2017 Apr 11;116(8):990-993. doi: 10.1038/bjc.2017.49. Epub 2017 Mar 2.

14.

Segmental hemangioma of the head and neck: High prevalence of PHACE syndrome.

Forde KM, Glover MT, Chong WK, Kinsler VA.

J Am Acad Dermatol. 2017 Feb;76(2):356-358. doi: 10.1016/j.jaad.2016.06.058. No abstract available.

PMID:
28089002
15.

The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.

Polubothu S, Kinsler VA.

Br J Dermatol. 2017 May;176(5):1385-1387. doi: 10.1111/bjd.15260. Epub 2017 Apr 21. No abstract available.

16.

Melanoma in congenital melanocytic naevi.

Kinsler VA, O'Hare P, Bulstrode N, Calonje JE, Chong WK, Hargrave D, Jacques T, Lomas D, Sebire NJ, Slater O.

Br J Dermatol. 2017 May;176(5):1131-1143. doi: 10.1111/bjd.15301. Epub 2017 Apr 4. Review.

17.

Copy number abnormalities in new or progressive 'neurocutaneous melanosis' confirm it to be primary CNS melanoma.

Kinsler VA, Polubothu S, Calonje JE, Chong WK, Thompson D, Jacques TS, Morrogh D.

Acta Neuropathol. 2017 Feb;133(2):329-331. doi: 10.1007/s00401-016-1651-0. Epub 2016 Dec 8. No abstract available.

18.

Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold - A Potential Therapeutic Intervention for Skin Diseases.

Chen W, Kinsler VA, Macmillan D, Di WL.

PLoS One. 2016 Nov 8;11(11):e0166268. doi: 10.1371/journal.pone.0166268. eCollection 2016.

19.

Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.

Castillo SD, Tzouanacou E, Zaw-Thin M, Berenjeno IM, Parker VE, Chivite I, Milà-Guasch M, Pearce W, Solomon I, Angulo-Urarte A, Figueiredo AM, Dewhurst RE, Knox RG, Clark GR, Scudamore CL, Badar A, Kalber TL, Foster J, Stuckey DJ, David AL, Phillips WA, Lythgoe MF, Wilson V, Semple RK, Sebire NJ, Kinsler VA, Graupera M, Vanhaesebroeck B.

Sci Transl Med. 2016 Mar 30;8(332):332ra43. doi: 10.1126/scitranslmed.aad9982.

20.

Extending the spectrum of AKT1 mosaicism: not just the Proteus syndrome.

Polubothu S, Al-Olabi L, Wilson L, Chong WK, Kinsler VA.

Br J Dermatol. 2016 Sep;175(3):612-4. doi: 10.1111/bjd.14478. Epub 2016 Jun 23. No abstract available.

21.

Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis.

Thomas AC, Zeng Z, Rivière JB, O'Shaughnessy R, Al-Olabi L, St-Onge J, Atherton DJ, Aubert H, Bagazgoitia L, Barbarot S, Bourrat E, Chiaverini C, Chong WK, Duffourd Y, Glover M, Groesser L, Hadj-Rabia S, Hamm H, Happle R, Mushtaq I, Lacour JP, Waelchli R, Wobser M, Vabres P, Patton EE, Kinsler VA.

J Invest Dermatol. 2016 Apr;136(4):770-778. doi: 10.1016/j.jid.2015.11.027. Epub 2016 Jan 14.

22.

Growth and hormone profiling in children with congenital melanocytic naevi.

Waelchli R, Williams J, Cole T, Dattani M, Hindmarsh P, Kennedy H, Martinez A, Khan S, Semple RK, White A, Sebire N, Healy E, Moore G, Kinsler VA.

Br J Dermatol. 2015 Dec;173(6):1471-8. doi: 10.1111/bjd.14091. Epub 2015 Nov 17. Erratum in: Br J Dermatol. 2016 Jul;175(1):226-7.

23.

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.

Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD.

J Invest Dermatol. 2015 Nov;135(11):2902. doi: 10.1038/jid.2015.230. Epub 2015 Jul 16. No abstract available.

24.

Classification of neurological abnormalities in children with congenital melanocytic naevus syndrome identifies magnetic resonance imaging as the best predictor of clinical outcome.

Waelchli R, Aylett SE, Atherton D, Thompson DJ, Chong WK, Kinsler VA.

Br J Dermatol. 2015 Sep;173(3):739-50. doi: 10.1111/bjd.13898. Epub 2015 Aug 27.

25.

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.

Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD.

J Invest Dermatol. 2015 Aug;135(8):2093-2101. doi: 10.1038/jid.2015.114. Epub 2015 Mar 27. Erratum in: J Invest Dermatol. 2015 Nov;135(11):2902.

26.

Congenital hemidysplasia with ichthyosiform naevus and limb defects (CHILD) syndrome without hemidysplasia.

Estapé A, Josifova D, Rampling D, Glover M, Kinsler VA.

Br J Dermatol. 2015 Jul;173(1):304-7. doi: 10.1111/bjd.13636. Epub 2015 May 28. No abstract available.

27.

The adverse effect profile of oral azathioprine in pediatric atopic dermatitis, and recommendations for monitoring.

Fuggle NR, Bragoli W, Mahto A, Glover M, Martinez AE, Kinsler VA.

J Am Acad Dermatol. 2015 Jan;72(1):108-14. doi: 10.1016/j.jaad.2014.08.048. Epub 2014 Nov 4.

28.

A novel microdeletion in LOR causing autosomal dominant loricrin keratoderma.

Kinsler VA, Drury S, Khan A, Waelchli R, Rukaite G, Barnicoat A, Lench N, Harper JI, O'Shaughnessy RF.

Br J Dermatol. 2015 Jan;172(1):262-4. doi: 10.1111/bjd.13361. Epub 2014 Dec 9. No abstract available.

29.

New vascular classification of port-wine stains: improving prediction of Sturge-Weber risk.

Waelchli R, Aylett SE, Robinson K, Chong WK, Martinez AE, Kinsler VA.

Br J Dermatol. 2014 Oct;171(4):861-7. doi: 10.1111/bjd.13203. Epub 2014 Oct 1.

30.

Next-generation sequencing of nevus spilus-type congenital melanocytic nevus: exquisite genotype-phenotype correlation in mosaic RASopathies.

Kinsler VA, Krengel S, Riviere JB, Waelchli R, Chapusot C, Al-Olabi L, Faivre L, Haenssle HA, Weibel L, Jeudy G, Vabres P.

J Invest Dermatol. 2014 Oct;134(10):2658-2660. doi: 10.1038/jid.2014.195. Epub 2014 Apr 21. No abstract available.

31.

Identifying a hyperkeratosis signature in autosomal recessive congenital ichthyosis: Mdm2 inhibition prevents hyperkeratosis in a rat ARCI model.

Youssef G, Ono M, Brown SJ, Kinsler VA, Sebire NJ, Harper JI, O'Shaughnessy RFL.

J Invest Dermatol. 2014 Mar;134(3):858-861. doi: 10.1038/jid.2013.374. Epub 2013 Sep 4. No abstract available.

32.

Immunohistochemical and ultrastructural features of congenital melanocytic naevus cells support a stem-cell phenotype.

Kinsler VA, Anderson G, Latimer B, Natarajan D, Healy E, Moore GE, Sebire NJ.

Br J Dermatol. 2013 Aug;169(2):374-83. doi: 10.1111/bjd.12323.

33.

Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS.

Kinsler VA, Thomas AC, Ishida M, Bulstrode NW, Loughlin S, Hing S, Chalker J, McKenzie K, Abu-Amero S, Slater O, Chanudet E, Palmer R, Morrogh D, Stanier P, Healy E, Sebire NJ, Moore GE.

J Invest Dermatol. 2013 Sep;133(9):2229-36. doi: 10.1038/jid.2013.70. Epub 2013 Feb 7. Erratum in: J Invest Dermatol. 2016 Nov;136(11):2326.

34.

Germline melanocortin-1-receptor genotype is associated with severity of cutaneous phenotype in congenital melanocytic nevi: a role for MC1R in human fetal development.

Kinsler VA, Abu-Amero S, Budd P, Jackson IJ, Ring SM, Northstone K, Atherton DJ, Bulstrode NW, Stanier P, Hennekam RC, Sebire NJ, Moore GE, Healy E.

J Invest Dermatol. 2012 Aug;132(8):2026-32. doi: 10.1038/jid.2012.95. Epub 2012 May 10.

35.

Neuropathology of neurocutaneous melanosis: histological foci of melanotic neurones and glia may be undetectable on MRI.

Kinsler VA, Paine SM, Anderson GW, Wijesekara DS, Sebire NJ, Chong WK, Harkness W, Aylett SE, Jacques TS.

Acta Neuropathol. 2012 Mar;123(3):453-6. doi: 10.1007/s00401-012-0945-0. No abstract available.

36.

Great Ormond Street Hospital for Children Registry for Congenital Melanocytic Naevi: prospective study 1988-2007. Part 2--Evaluation of treatments.

Kinsler VA, Birley J, Atherton DJ.

Br J Dermatol. 2009 Feb;160(2):387-92. doi: 10.1111/j.1365-2133.2008.08901.x. Epub 2008 Oct 22. Erratum in: Br J Dermatol. 2009 Feb;160(2):474.

PMID:
19016692
37.

Great Ormond Street Hospital for Children Registry for congenital melanocytic naevi: prospective study 1988-2007. Part 1-epidemiology, phenotype and outcomes.

Kinsler VA, Birley J, Atherton DJ.

Br J Dermatol. 2009 Jan;160(1):143-50. doi: 10.1111/j.1365-2133.2008.08849.x. Epub 2008 Oct 22.

PMID:
18811688
38.

Complications of congenital melanocytic naevi in children: analysis of 16 years' experience and clinical practice.

Kinsler VA, Chong WK, Aylett SE, Atherton DJ.

Br J Dermatol. 2008 Sep;159(4):907-14. doi: 10.1111/j.1365-2133.2008.08775.x. Epub 2008 Jul 30.

PMID:
18671780
39.

Diffuse cutaneous mastocytosis treated with psoralen photochemotherapy: case report and review of the literature.

Kinsler VA, Hawk JL, Atherton DJ.

Br J Dermatol. 2005 Jan;152(1):179-80. Review. No abstract available.

PMID:
15656827
40.

Central nervous system imaging and congenital melanocytic naevi.

Kinsler VA, Aylett SE, Coley SC, Chong WK, Atherton DJ.

Arch Dis Child. 2001 Feb;84(2):152-5.

41.

The effect of the oxytocin antagonists F314 and F792 on the in vitro contractility of human myometrium.

Kinsler VA, Thornton S, Ashford ML, Melin P, Smith SK.

Br J Obstet Gynaecol. 1996 Apr;103(4):373-5. No abstract available.

PMID:
8605137

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