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Items: 1 to 50 of 2842

1.

Protein Allostery in Rational Drug Design.

Kinoshita T.

Adv Exp Med Biol. 2019;1163:45-64. doi: 10.1007/978-981-13-8719-7_3.

PMID:
31707699
2.

Systemic and Ocular Determinants of Choroidal Structures on Optical Coherence Tomography of Eyes with Diabetes and Diabetic Retinopathy.

Kinoshita T, Imaizumi H, Shimizu M, Mori J, Hatanaka A, Aoki S, Miyamoto H, Iwasaki M, Murao F, Niki M, Sano H, Sonoda S, Sakamoto T, Mitamura Y.

Sci Rep. 2019 Nov 7;9(1):16228. doi: 10.1038/s41598-019-52750-0.

3.

An isoform-selective inhibitor of tropomyosin receptor kinase A behaves as molecular glue.

Furuya N, Momose T, Katsuno K, Fushimi N, Muranaka H, Handa C, Sawa M, Ozawa T, Kinoshita T.

Bioorg Med Chem Lett. 2019 Oct 28:126775. doi: 10.1016/j.bmcl.2019.126775. [Epub ahead of print]

PMID:
31699609
4.

Effect of tranexamic acid on mortality in patients with haemoptysis: a nationwide study.

Kinoshita T, Ohbe H, Matsui H, Fushimi K, Ogura H, Yasunaga H.

Crit Care. 2019 Nov 6;23(1):347. doi: 10.1186/s13054-019-2620-5.

5.

Caspase-7 mediates caspase-1-induced apoptosis independently of Bid.

Mahib MR, Hosojima S, Kushiyama H, Kinoshita T, Shiroishi T, Suda T, Tsuchiya K.

Microbiol Immunol. 2019 Nov 5. doi: 10.1111/1348-0421.12756. [Epub ahead of print]

PMID:
31687791
6.

Development of a deep learning model to identify hyperdense MCA sign in patients with acute ischemic stroke.

Shinohara Y, Takahashi N, Lee Y, Ohmura T, Kinoshita T.

Jpn J Radiol. 2019 Oct 31. doi: 10.1007/s11604-019-00894-4. [Epub ahead of print]

PMID:
31673998
7.

DA-EPOCH-R combined with high-dose methotrexate in patients with newly diagnosed stage II-IV CD5-positive diffuse large B-cell lymphoma: a single-arm, open-label, phase 2 study.

Miyazaki K, Asano N, Yamada T, Miyawaki K, Sakai R, Igarashi T, Nishikori M, Ohata K, Sunami K, Yoshida I, Yamamoto G, Takahashi N, Okamoto M, Yano H, Nishimura Y, Tamaru S, Nishikawa M, Izutsu K, Kinoshita T, Suzumiya J, Ohshima K, Kato K, Katayama N, Yamaguchi M; CD5+ DLBCL Treatment Study Group.

Haematologica. 2019 Oct 24. pii: haematol.2019.231076. doi: 10.3324/haematol.2019.231076. [Epub ahead of print]

8.

Frequency of Common Copy-Number Variations at 15q11.2q13 in Sperm of Healthy Men.

Kinoshita T, Mikami M, Ayabe T, Matsubara K, Ono H, Ohki K, Fukami M, Katoh-Fukui Y.

Cytogenet Genome Res. 2019 Oct 22. doi: 10.1159/000503267. [Epub ahead of print]

PMID:
31639787
9.

Ensemble structural analyses depict the regulatory mechanism of non-phosphorylated human MAP2K4.

Matsumoto T, Yamano A, Murakawa Y, Fukada H, Sawa M, Kinoshita T.

Biochem Biophys Res Commun. 2019 Oct 18. pii: S0006-291X(19)31979-5. doi: 10.1016/j.bbrc.2019.10.086. [Epub ahead of print]

PMID:
31635803
10.

Correction to: Vascular endothelial PDPK1 plays a pivotal role in the maintenance of pancreatic beta cell mass and function in adult male mice.

Obata A, Kimura T, Obata Y, Shimoda M, Kinoshita T, Kohara K, Okauchi S, Hirukawa H, Kamei S, Nakanishi S, Mune T, Kaku K, Kaneto H.

Diabetologia. 2019 Oct 11. doi: 10.1007/s00125-019-04982-y. [Epub ahead of print]

PMID:
31605154
11.

OCCUPATIONAL RADIATION EXPOSURE DOSE OF THE EYE IN DEPARTMENT OF CARDIAC ARRHYTHMIA PHYSICIAN.

Kato M, Chida K, Ishida T, Sasaki F, Toyoshima H, Oosaka H, Terata K, Abe Y, Kinoshita T.

Radiat Prot Dosimetry. 2019 Oct 12. pii: ncz175. doi: 10.1093/rpd/ncz175. [Epub ahead of print]

PMID:
31605141
12.

Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development.

Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G, Holers VM, Huber-Lang M, Kinoshita T, Mollnes TE, Montgomery RA, Morgan BP, Nilsson B, Pio R, Ricklin D, Risitano AM, Taylor RP, Mantovani A, Ioannidis JPA, Lambris JD.

Nat Immunol. 2019 Oct 11. doi: 10.1038/s41590-019-0531-x. [Epub ahead of print]

PMID:
31605100
13.

Radiosynthesis of 18F-labeled d-allose.

Yamamoto H, Wada K, Toyohara J, Tago T, Ibaraki M, Kinoshita T, Yamamoto Y, Nishiyama Y, Kudomi N.

Carbohydr Res. 2019 Dec 1;486:107827. doi: 10.1016/j.carres.2019.107827. Epub 2019 Sep 27.

PMID:
31586720
14.

Ileal conduit necrosis after total pelvic exenteration for recurrence of gastrointestinal stromal tumor.

Komori K, Okuno N, Kinoshita T, Oshiro T, Ouchi A, Ito S, Abe T, Senda Y, Misawa K, Ito Y, Uemura N, Natsume S, Higaki E, Okuno M, Hosoi T, An B, Hayashi D, Uchino T, Kunitomo A, Oki S, Takano J, Suenaga Y, Maeda S, Dei H, Numata Y, Shimizu Y.

Nagoya J Med Sci. 2019 Aug;81(3):529-534. doi: 10.18999/nagjms.81.3.529.

15.

'Stealth' corporate innovation: an emerging threat for therapeutic drug development.

Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G, Holers VM, Huber-Lang M, Kinoshita T, Mollnes TE, Montgomery RA, Morgan BP, Nilsson B, Pio R, Ricklin D, Risitano AM, Taylor RP, Mantovani A, Ioannidis JPA, Lambris JD.

Nat Immunol. 2019 Sep 27. doi: 10.1038/s41590-019-0503-1. [Epub ahead of print] No abstract available. Erratum in: Nat Immunol. 2019 Oct 11;:.

PMID:
31562490
16.

Structure-function study of a novel inhibitor of the casein kinase 1 family in Arabidopsis thaliana.

Saito AN, Matsuo H, Kuwata K, Ono A, Kinoshita T, Yamaguchi J, Nakamichi N.

Plant Direct. 2019 Sep 17;3(9):e00172. doi: 10.1002/pld3.172. eCollection 2019 Sep.

17.

Structural basis for the specific cleavage of core-fucosylated N-glycans by endo-β-N-acetylglucosaminidase from the fungus Cordyceps militaris.

Seki H, Huang Y, Arakawa T, Yamada C, Kinoshita T, Iwamoto S, Higuchi Y, Takegawa K, Fushinobu S.

J Biol Chem. 2019 Nov 8;294(45):17143-17154. doi: 10.1074/jbc.RA119.010842. Epub 2019 Sep 23.

PMID:
31548313
18.

Perioperative Management of a Patient With Cornelia de Lange Syndrome and Tetralogy of Fallot.

Nakajima A, Ohshima A, Fukayama H, Kinoshita T.

Anesth Prog. 2019 Fall;66(3):159-161. doi: 10.2344/anpr-66-04-02.

PMID:
31545670
19.

Spinal cord collateral flow during antegrade cerebral perfusion for aortic arch surgery.

Kinoshita T, Yoshida H, Hachiro K, Suzuki T, Asai T.

J Thorac Cardiovasc Surg. 2019 Aug 25. pii: S0022-5223(19)31642-3. doi: 10.1016/j.jtcvs.2019.07.088. [Epub ahead of print]

PMID:
31543306
20.

Efficacy of Postoperative Chemotherapy After Resection that Leaves No Macroscopically Visible Disease of Gastric Cancer with Positive Peritoneal Lavage Cytology (CY1) or Localized Peritoneum Metastasis (P1a): A Multicenter Retrospective Study.

Yamaguchi T, Takashima A, Nagashima K, Makuuchi R, Aizawa M, Ohashi M, Tashiro K, Yamada T, Kinoshita T, Hata H, Kawachi Y, Kawabata R, Tsuji T, Hihara J, Sakamoto T, Fukagawa T, Katai H, Higuchi K, Boku N.

Ann Surg Oncol. 2019 Sep 18. doi: 10.1245/s10434-019-07697-x. [Epub ahead of print]

PMID:
31535301
21.

3,4-Dibromo-7-Azaindole Modulates Arabidopsis Circadian Clock by Inhibiting Casein Kinase 1 Activity.

Ono A, Sato A, Fujimoto KJ, Matsuo H, Yanai T, Kinoshita T, Nakamichi N.

Plant Cell Physiol. 2019 Nov 1;60(11):2360-2368. doi: 10.1093/pcp/pcz183.

PMID:
31529098
22.

Surgical Strategy for Rectovaginal Fistula After Colorectal Anastomosis at a High-volume Cancer Center According to Image Type and Colonoscopy Findings.

Komori K, Kinoshita T, Oshiro T, Ouchi A, Ito S, Abe T, Senda Y, Misawa K, Ito Y, Natsume S, Higaki E, Okuno M, Hosoi T, Nagao T, Kunitomo A, Oki S, Takano J, Suenaga Y, Maeda S, Dei H, Numata Y, Shimizu Y.

Anticancer Res. 2019 Sep;39(9):5097-5103. doi: 10.21873/anticanres.13704.

PMID:
31519621
23.

Development of a High-Throughput Screening-Compatible Assay for Discovery of GPR3 Inverse Agonists Using a cAMP Biosensor.

Ayukawa K, Suzuki C, Ogasawara H, Kinoshita T, Furuno M, Suzuki G.

SLAS Discov. 2019 Sep 13:2472555219875101. doi: 10.1177/2472555219875101. [Epub ahead of print]

PMID:
31516076
24.

Simultaneous Separation of Triacylglycerol Enantiomers and Positional Isomers by Chiral High Performance Liquid Chromatography Coupled with Mass Spectrometry.

Nagai T, Kinoshita T, Kasamatsu E, Yoshinaga K, Mizobe H, Yoshida A, Itabashi Y, Gotoh N.

J Oleo Sci. 2019 Oct 3;68(10):1019-1026. doi: 10.5650/jos.ess19122. Epub 2019 Sep 11.

25.

Donor Site Evaluation After Osteochondral Autograft Transplantation for Capitellar Osteochondritis Dissecans.

Matsuura T, Hashimoto Y, Kinoshita T, Nishino K, Nishida Y, Takigami J, Katsuda H, Shimada N.

Am J Sports Med. 2019 Oct;47(12):2836-2843. doi: 10.1177/0363546519871064. Epub 2019 Sep 10.

PMID:
31503508
26.

A case of successful cryoballoon ablation of paroxysmal atrial fibrillation originating from a persistent left superior vena cava.

Fujino T, Yuzawa H, Kinoshita T, Shinohara M, Okishige K, Ikeda T.

J Cardiol Cases. 2019 May 23;20(3):77-80. doi: 10.1016/j.jccase.2019.04.005. eCollection 2019 Sep.

27.

Risk stratification for cardiac mortality using electrocardiographic markers based on 24-hour Holter recordings: the JANIES-SHD study.

Kinoshita T, Hashimoto K, Yoshioka K, Miwa Y, Yodogawa K, Watanabe E, Nakamura K, Nakagawa M, Nakamura K, Watanabe T, Yusu S, Tachibana M, Nakahara S, Mizumaki K, Ikeda T.

J Cardiol. 2019 Aug 29. pii: S0914-5087(19)30238-2. doi: 10.1016/j.jjcc.2019.07.012. [Epub ahead of print]

PMID:
31474497
28.

Efficacy of Scalp Cooling in Preventing and Recovering From Chemotherapy-Induced Alopecia in Breast Cancer Patients: The HOPE Study.

Kinoshita T, Nakayama T, Fukuma E, Inokuchi M, Ishiguro H, Ogo E, Kikuchi M, Jinno H, Yamazaki N, Toi M.

Front Oncol. 2019 Aug 6;9:733. doi: 10.3389/fonc.2019.00733. eCollection 2019.

29.
30.

Pre-stimulus Brain Activity Is Associated With State-Anxiety Changes During Single-Session Transcranial Direct Current Stimulation.

Nishida K, Koshikawa Y, Morishima Y, Yoshimura M, Katsura K, Ueda S, Ikeda S, Ishii R, Pascual-Marqui R, Kinoshita T.

Front Hum Neurosci. 2019 Aug 8;13:266. doi: 10.3389/fnhum.2019.00266. eCollection 2019.

31.

Complement and inflammasome overactivation mediates paroxysmal nocturnal hemoglobinuria with autoinflammation.

Höchsmann B, Murakami Y, Osato M, Knaus A, Kawamoto M, Inoue N, Hirata T, Murata S, Anliker M, Eggerman T, Jäger M, Floettmann R, Höllein A, Murase S, Ueda Y, Nishimura JI, Kanakura Y, Kohara N, Schrezenmeier H, Krawitz PM, Kinoshita T.

J Clin Invest. 2019 Oct 22. pii: 123501. doi: 10.1172/JCI123501. [Epub ahead of print]

32.

HER2 heterogeneity is a poor prognosticator for HER2-positive gastric cancer.

Kaito A, Kuwata T, Tokunaga M, Shitara K, Sato R, Akimoto T, Kinoshita T.

World J Clin Cases. 2019 Aug 6;7(15):1964-1977. doi: 10.12998/wjcc.v7.i15.1964.

33.

Efficacy of clarithromycin against H5N1 and H7N9 avian influenza a virus infection in cynomolgus monkeys.

Arikata M, Itoh Y, Shichinohe S, Nakayama M, Ishigaki H, Kinoshita T, Le MQ, Kawaoka Y, Ogasawara K, Shimizu T.

Antiviral Res. 2019 Nov;171:104591. doi: 10.1016/j.antiviral.2019.104591. Epub 2019 Aug 14.

PMID:
31421167
34.

Left ventricular mass regression in patients without patient-prosthesis mismatch after aortic valve replacement for aortic stenosis.

Hachiro K, Kinoshita T, Asai T, Suzuki T.

Gen Thorac Cardiovasc Surg. 2019 Aug 14. doi: 10.1007/s11748-019-01188-2. [Epub ahead of print]

PMID:
31414321
35.

Identification and characterization of POU class V family genes in Japanese red bellied newt, Cynops pyrrhogaster.

Hasegawa S, Nakao I, Ootani Y, Ogawa A, Takano M, Kinoshita T.

Zygote. 2019 Oct;27(5):329-336. doi: 10.1017/S0967199419000339. Epub 2019 Aug 15.

PMID:
31412969
36.

Impact of Mitral Surgery for Mitral Regurgitation on Coexisting Aortic Regurgitation.

Hachiro K, Kinoshita T, Asai T, Suzuki T.

Ann Thorac Cardiovasc Surg. 2019 Aug 7. doi: 10.5761/atcs.oa.19-00141. [Epub ahead of print]

37.

Changes of choroidal structure and circulation after water drinking test in normal eyes.

Nagasato D, Mitamura Y, Egawa M, Kameoka M, Nagasawa T, Tabuchi H, Kinoshita T, Sonoda S, Sakamoto T.

Graefes Arch Clin Exp Ophthalmol. 2019 Nov;257(11):2391-2399. doi: 10.1007/s00417-019-04427-7. Epub 2019 Aug 5.

PMID:
31378831
38.

Two Cases of Equine Multinodular Pulmonary Fibrosis in Japan.

Ochi A, Sekiguchi M, Tsujimura K, Kinoshita T, Ueno T, Katayama Y.

J Comp Pathol. 2019 Jul;170:46-52. doi: 10.1016/j.jcpa.2019.05.007. Epub 2019 Jun 13.

PMID:
31375158
39.

Asymmetric Phosphorus Incorporation in Homoepitaxial P-Doped (111) Diamond Revealed by Photoelectron Holography.

Yokoya T, Terashima K, Takeda A, Fukura T, Fujiwara H, Muro T, Kinoshita T, Kato H, Yamasaki S, Oguchi T, Wakita T, Muraoka Y, Matsushita T.

Nano Lett. 2019 Sep 11;19(9):5915-5919. doi: 10.1021/acs.nanolett.9b01481. Epub 2019 Aug 21.

PMID:
31373825
40.

Mutations in PIGU Impair the Function of the GPI Transamidase Complex, Causing Severe Intellectual Disability, Epilepsy, and Brain Anomalies.

Knaus A, Kortüm F, Kleefstra T, Stray-Pedersen A, Đukić D, Murakami Y, Gerstner T, van Bokhoven H, Iqbal Z, Horn D, Kinoshita T, Hempel M, Krawitz PM.

Am J Hum Genet. 2019 Aug 1;105(2):395-402. doi: 10.1016/j.ajhg.2019.06.009. Epub 2019 Jul 25.

PMID:
31353022
41.

Regulation of stomatal opening and histone modification by photoperiod in Arabidopsis thaliana.

Aoki S, Toh S, Nakamichi N, Hayashi Y, Wang Y, Suzuki T, Tsuji H, Kinoshita T.

Sci Rep. 2019 Jul 22;9(1):10054. doi: 10.1038/s41598-019-46440-0.

42.

Taxane-based combinations as adjuvant chemotherapy for node-positive ER-positive breast cancer based on 2004-2009 data from the Breast Cancer Registry of the Japanese Breast Cancer Society.

Hojo T, Masuda N, Iwamoto T, Niikura N, Anan K, Aogi K, Ohnishi T, Yamauchi C, Yoshida M, Kinoshita T, Masuoka H, Sagara Y, Sakatani T, Kojima Y, Tsuda H, Kumamaru H, Miyata H, Nakamura S.

Breast Cancer. 2019 Jul 20. doi: 10.1007/s12282-019-00997-w. [Epub ahead of print]

PMID:
31327134
43.

Extra-perigastric Extranodal Metastasis is a Significant Prognostic Factor in Node-Positive Gastric Cancer.

Tonouchi A, Sugano M, Tokunaga M, Sugita S, Watanabe M, Sato R, Kaito A, Akimoto T, Ochiai A, Kinoshita T, Kuwata T.

World J Surg. 2019 Oct;43(10):2499-2505. doi: 10.1007/s00268-019-05076-x.

PMID:
31312947
44.

Different risks of nodal metastasis by tumor location in remnant gastric cancer after curative gastrectomy for gastric cancer.

Takahashi K, Yoshikawa T, Morita S, Kinoshita T, Yura M, Otsuki S, Tokunaga M, Yamagata Y, Kaito A, Katai H.

Gastric Cancer. 2019 Jul 13. doi: 10.1007/s10120-019-00989-x. [Epub ahead of print]

PMID:
31302790
45.

Circulating soluble LR11, a differentiation regulator for vascular cells, is increased during pregnancy and exaggerated in patients with pre-eclampsia.

Ishida H, Jiang M, Ebinuma H, Hiruta N, Schneider WJ, Kinoshita T, Bujo H.

Clin Chim Acta. 2019 Oct;497:172-177. doi: 10.1016/j.cca.2019.07.001. Epub 2019 Jul 9.

PMID:
31299181
46.

A promiscuous kinase inhibitor delineates the conspicuous structural features of protein kinase CK2a1.

Tsuyuguchi M, Nakaniwa T, Sawa M, Nakanishi I, Kinoshita T.

Acta Crystallogr F Struct Biol Commun. 2019 Jul 1;75(Pt 7):515-519. doi: 10.1107/S2053230X19008951. Epub 2019 Jul 4.

PMID:
31282872
47.

Mutations in PIGB Cause an Inherited GPI Biosynthesis Defect with an Axonal Neuropathy and Metabolic Abnormality in Severe Cases.

Murakami Y, Nguyen TTM, Baratang N, Raju PK, Knaus A, Ellard S, Jones G, Lace B, Rousseau J, Ajeawung NF, Kamei A, Minase G, Akasaka M, Araya N, Koshimizu E, van den Ende J, Erger F, Altmüller J, Krumina Z, Strautmanis J, Inashkina I, Stavusis J, El-Gharbawy A, Sebastian J, Puri RD, Kulshrestha S, Verma IC, Maier EM, Haack TB, Israni A, Baptista J, Gunning A, Rosenfeld JA, Liu P, Joosten M, Rocha ME, Hashem MO, Aldhalaan HM, Alkuraya FS, Miyatake S, Matsumoto N, Krawitz PM, Rossignol E, Kinoshita T, Campeau PM.

Am J Hum Genet. 2019 Aug 1;105(2):384-394. doi: 10.1016/j.ajhg.2019.05.019. Epub 2019 Jun 27.

PMID:
31256876
48.

A long-term survival case of Sister Mary Joseph's nodule caused by colon cancer and treated with a multidisciplinary approach.

Iwata Y, Kinoshita T, Kimura K, Komori K, Hayashi D, Akazawa T, Shigeyoshi I, Tsutsuyama M, Kawakami J, Ouchi A, Natsume S, Uemura N, Ito Y, Misawa K, Senda Y, Abe T, Ito S, Tajika M, Yatabe Y, Yoshida K, Shimizu Y.

Nagoya J Med Sci. 2019 May;81(2):325-329. doi: 10.18999/nagjms.81.2.325.

49.

Establishment of Novel Gastric Cancer Patient-Derived Xenografts and Cell Lines: Pathological Comparison between Primary Tumor, Patient-Derived, and Cell-Line Derived Xenografts.

Kuwata T, Yanagihara K, Iino Y, Komatsu T, Ochiai A, Sekine S, Taniguchi H, Katai H, Kinoshita T, Ohtsu A.

Cells. 2019 Jun 14;8(6). pii: E585. doi: 10.3390/cells8060585.

50.

Explicit prognostic disclosure to Asian women with breast cancer: A randomized, scripted video-vignette study (J-SUPPORT1601).

Mori M, Fujimori M, van Vliet LM, Yamaguchi T, Shimizu C, Kinoshita T, Morishita-Kawahara M, Inoue A, Inoguchi H, Matsuoka Y, Bruera E, Morita T, Uchitomi Y.

Cancer. 2019 Oct 1;125(19):3320-3329. doi: 10.1002/cncr.32327. Epub 2019 Jun 17.

PMID:
31206639

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