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Items: 1 to 50 of 238

1.

Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration.

Zou J, Feng H, Sood R, Kinnunen PKJ, Pyykko I.

Nanoscale Res Lett. 2017 Dec;12(1):372. doi: 10.1186/s11671-017-2142-5. Epub 2017 May 25.

2.

Acyl Chain Disorder and Azelaoyl Orientation in Lipid Membranes Containing Oxidized Lipids.

Mendes Ferreira T, Sood R, Bärenwald R, Carlström G, Topgaard D, Saalwächter K, Kinnunen PK, Ollila OH.

Langmuir. 2016 Jun 28;32(25):6524-33. doi: 10.1021/acs.langmuir.6b00788. Epub 2016 Jun 17.

PMID:
27260273
3.

Interactions and dynamics of two extended conformation adapting phosphatidylcholines in model biomembranes.

Amirkavei M, Kinnunen PK.

Biochim Biophys Acta. 2016 Feb;1858(2):264-73. doi: 10.1016/j.bbamem.2015.12.006. Epub 2015 Dec 4.

4.

Correction: Formation of lipid/peptide tubules by IAPP and temporin B on supported lipid membranes.

Kinnunen PK, Domanov YA, Mattila JP, Varis T.

Soft Matter. 2015 Dec 21;11(47):9218. doi: 10.1039/c5sm90202a.

PMID:
26580712
5.

Formation of lipid/peptide tubules by IAPP and temporin B on supported lipid membranes.

Kinnunen PK, Domanov YA, Mattila JP, Varis T.

Soft Matter. 2015 Dec 21;11(47):9188-200. doi: 10.1039/b925228b. Erratum in: Soft Matter. 2015 Dec 21;11(47):9218.

PMID:
26575388
6.

Phospholipid lateral diffusion in phosphatidylcholine-sphingomyelin-cholesterol monolayers; effects of oxidatively truncated phosphatidylcholines.

Parkkila P, Stefl M, Olżyńska A, Hof M, Kinnunen PK.

Biochim Biophys Acta. 2015 Jan;1848(1 Pt A):167-73. doi: 10.1016/j.bbamem.2014.10.025. Epub 2014 Oct 25.

7.

Novel endosomolytic peptides for enhancing gene delivery in nanoparticles.

Ahmad A, Ranjan S, Zhang W, Zou J, Pyykkö I, Kinnunen PK.

Biochim Biophys Acta. 2015 Feb;1848(2):544-53. doi: 10.1016/j.bbamem.2014.11.008. Epub 2014 Nov 15.

8.

Identification of Sphingomyelinase on the Surface of Chlamydia pneumoniae: Possible Role in the Entry into Its Host Cells.

Peñate Medina TA, Korhonen JT, Lahesmaa R, Puolakkainen M, Peñate Medina O, Kinnunen PK.

Interdiscip Perspect Infect Dis. 2014;2014:412827. doi: 10.1155/2014/412827. Epub 2014 Mar 13.

9.

Principles of rational design of thermally targeted liposomes for local drug delivery.

Tejera-Garcia R, Parkkila P, Zamotin V, Kinnunen PK.

Nanomedicine. 2014 Aug;10(6):1243-52. doi: 10.1016/j.nano.2014.03.013. Epub 2014 Mar 28.

PMID:
24685945
10.

Human heat shock protein 70 (Hsp70) as a peripheral membrane protein.

Mahalka AK, Kirkegaard T, Jukola LT, Jäättelä M, Kinnunen PK.

Biochim Biophys Acta. 2014 May;1838(5):1344-61. doi: 10.1016/j.bbamem.2014.01.022. Epub 2014 Jan 28.

11.

Golgi-Associated plant Pathogenesis Related protein 1 (GAPR-1) forms amyloid-like fibrils by interaction with acidic phospholipids and inhibits Aβ aggregation.

Olrichs NK, Mahalka AK, Kaloyanova D, Kinnunen PK, Bernd Helms J.

Amyloid. 2014 Jun;21(2):88-96. doi: 10.3109/13506129.2014.882304. Epub 2014 Jan 29.

PMID:
24471790
12.

Pathway and morphological transformation of liposome nanocarriers after release from a novel sustained inner-ear delivery system.

Zou J, Sood R, Zhang Y, Kinnunen PK, Pyykkö I.

Nanomedicine (Lond). 2014 Jul;9(14):2143-55. doi: 10.2217/nnm.13.181. Epub 2014 Jan 28.

PMID:
24471501
13.

Impact of oxidized phospholipids on the structural and dynamic organization of phospholipid membranes: a combined DSC and solid state NMR study.

Wallgren M, Beranova L, Pham QD, Linh K, Lidman M, Procek J, Cyprych K, Kinnunen PK, Hof M, Gröbner G.

Faraday Discuss. 2013;161:499-513; discussion 563-89.

PMID:
23805755
14.

Class specific peptide inhibitors for secretory phospholipases A2.

Mahalka AK, Kinnunen PK.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):349-53. doi: 10.1016/j.bbrc.2013.05.110. Epub 2013 Jun 4.

PMID:
23747420
15.

Oxidized phosphatidylcholines in membrane-level cellular signaling: from biophysics to physiology and molecular pathology.

Volinsky R, Kinnunen PK.

FEBS J. 2013 Jun;280(12):2806-16. doi: 10.1111/febs.12247. Epub 2013 Apr 17. Review.

16.

Oxidized phosphatidylcholines promote phase separation of cholesterol-sphingomyelin domains.

Volinsky R, Paananen R, Kinnunen PK.

Biophys J. 2012 Jul 18;103(2):247-54. doi: 10.1016/j.bpj.2012.06.017. Epub 2012 Jul 17.

17.

Peptide-mediated targeting of liposomes to TrkB receptor-expressing cells.

Ranjan S, Sood R, Dudas J, Glueckert R, Schrott-Fischer A, Roy S, Pyykkö I, Kinnunen PK.

Int J Nanomedicine. 2012;7:3475-85. doi: 10.2147/IJN.S32367. Epub 2012 Jul 6.

18.

Gravimetric determination of phospholipid concentration.

Tejera-Garcia R, Connell L, Shaw WA, Kinnunen PK.

Chem Phys Lipids. 2012 Sep;165(6):689-95. doi: 10.1016/j.chemphyslip.2012.06.005. Epub 2012 Jul 5.

PMID:
22771452
19.

Size-dependent passage of liposome nanocarriers with preserved posttransport integrity across the middle-inner ear barriers in rats.

Zou J, Sood R, Ranjan S, Poe D, Ramadan UA, Pyykkö I, Kinnunen PK.

Otol Neurotol. 2012 Jun;33(4):666-73. doi: 10.1097/MAO.0b013e318254590e.

PMID:
22569149
20.

Protein-oxidized phospholipid interactions in cellular signaling for cell death: from biophysics to clinical correlations.

Kinnunen PK, Kaarniranta K, Mahalka AK.

Biochim Biophys Acta. 2012 Oct;1818(10):2446-55. doi: 10.1016/j.bbamem.2012.04.008. Epub 2012 Apr 19. Review.

21.

Minimally invasive drug delivery to the cochlea through application of nanoparticles to the round window membrane.

Buckiová D, Ranjan S, Newman TA, Johnston AH, Sood R, Kinnunen PK, Popelář J, Chumak T, Syka J.

Nanomedicine (Lond). 2012 Sep;7(9):1339-54. Epub 2012 Apr 4.

PMID:
22475648
22.

Oxidized phosphatidylcholines facilitate phospholipid flip-flop in liposomes.

Volinsky R, Cwiklik L, Jurkiewicz P, Hof M, Jungwirth P, Kinnunen PK.

Biophys J. 2011 Sep 21;101(6):1376-84. doi: 10.1016/j.bpj.2011.07.051. Epub 2011 Sep 20.

23.

Making unilamellar liposomes using focused ultrasound.

Tejera-Garcia R, Ranjan S, Zamotin V, Sood R, Kinnunen PK.

Langmuir. 2011 Aug 16;27(16):10088-97. doi: 10.1021/la201708x. Epub 2011 Jul 21.

PMID:
21740027
24.

Activation of phospholipase A2 by Hsp70 in vitro.

Mahalka AK, Code C, Jahromi BR, Kirkegaard T, Jäättelä M, Kinnunen PK.

Biochim Biophys Acta. 2011 Oct;1808(10):2569-72. doi: 10.1016/j.bbamem.2011.06.002. Epub 2011 Jun 13. Erratum in: Biochim Biophys Acta. 2014 Jul;1838(7):1921. Rezaijahromi, Behnam [corrected to Jahromi, Behnam Rezai].

25.

1-Palmitoyl-2-(9'-oxononanoyl)-sn-glycero-3-phosphocholine, an oxidized phospholipid, accelerates Finnish type familial gelsolin amyloidosis in vitro.

Mahalka AK, Maury CP, Kinnunen PK.

Biochemistry. 2011 Jun 7;50(22):4877-89. doi: 10.1021/bi200195s. Epub 2011 May 13.

PMID:
21545139
26.

Visualization of intracellular trafficking of Math1 protein in different cell types with a newly-constructed nonviral gene delivery plasmid.

Zhang W, Zhang Y, Sood R, Ranjan S, Surovtseva E, Ahmad A, Kinnunen PK, Pyykkö I, Zou J.

J Gene Med. 2011 Feb;13(2):134-44. doi: 10.1002/jgm.1537.

PMID:
21308898
27.

Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium.

Zou J, Sood R, Ranjan S, Poe D, Ramadan UA, Kinnunen PK, Pyykkö I.

J Nanobiotechnology. 2010 Dec 18;8:32. doi: 10.1186/1477-3155-8-32.

28.

Cytochrome c-lipid interactions: new insights from resonance energy transfer.

Trusova VM, Gorbenko GP, Molotkovsky JG, Kinnunen PK.

Biophys J. 2010 Sep 22;99(6):1754-63. doi: 10.1016/j.bpj.2010.06.017.

29.

Characterization of hydrophobic interaction and antioxidant properties of the phenothiazine nucleus in mitochondrial and model membranes.

Borges MB, Dos Santos CG, Yokomizo CH, Sood R, Vitovic P, Kinnunen PK, Rodrigues T, Nantes IL.

Free Radic Res. 2010 Sep;44(9):1054-63. doi: 10.3109/10715762.2010.498826.

PMID:
20815768
30.

Activation of phospholipase A2 by 1-palmitoyl-2-(9'-oxo-nonanoyl)-sn-glycero-3-phosphocholine in vitro.

Code C, Mahalka AK, Bry K, Kinnunen PK.

Biochim Biophys Acta. 2010 Aug;1798(8):1593-600. doi: 10.1016/j.bbamem.2010.05.002. Epub 2010 May 10.

31.

The intermediate state of DMPG is stabilized by enhanced positive spontaneous curvature.

Alakoskela JM, Parry MJ, Kinnunen PK.

Langmuir. 2010 Apr 6;26(7):4892-900. doi: 10.1021/la100411p.

PMID:
20205407
32.

Interlamellar coupling of phospholipid bilayers in liposomes: an emergent property of lipid rearrangement.

Parry MJ, Hagen M, Mouritsen OG, Kinnunen PK, Alakoskela JM.

Langmuir. 2010 Apr 6;26(7):4909-15. doi: 10.1021/la9034547.

PMID:
20180577
33.

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, Kinnunen PK, Nylandsted J, Jäättelä M.

Nature. 2010 Jan 28;463(7280):549-53. doi: 10.1038/nature08710.

PMID:
20111001
34.

Screening for the drug-phospholipid interaction: correlation to phospholipidosis.

Alakoskela JM, Vitovic P, Kinnunen PK.

ChemMedChem. 2009 Aug;4(8):1224-51. doi: 10.1002/cmdc.200900052. Review.

PMID:
19551800
35.

Binding of amphipathic alpha-helical antimicrobial peptides to lipid membranes: lessons from temporins B and L.

Mahalka AK, Kinnunen PK.

Biochim Biophys Acta. 2009 Aug;1788(8):1600-9. doi: 10.1016/j.bbamem.2009.04.012. Epub 2009 Apr 24. Review.

36.

Cytochrome c induces lipid demixing in weakly charged phosphatidylcholine/phosphatidylglycerol model membranes as evidenced by resonance energy transfer.

Gorbenko GP, Trusova VM, Molotkovsky JG, Kinnunen PK.

Biochim Biophys Acta. 2009 Jun;1788(6):1358-65. doi: 10.1016/j.bbamem.2009.03.007. Epub 2009 Mar 25.

37.

Activation of phospholipase A2 by temporin B: formation of antimicrobial peptide-enzyme amyloid-type cofibrils.

Code C, Domanov YA, Killian JA, Kinnunen PK.

Biochim Biophys Acta. 2009 May;1788(5):1064-72. doi: 10.1016/j.bbamem.2009.03.002. Epub 2009 Mar 11.

38.

Molecular mechanisms of membrane deformation by I-BAR domain proteins.

Saarikangas J, Zhao H, Pykäläinen A, Laurinmäki P, Mattila PK, Kinnunen PK, Butcher SJ, Lappalainen P.

Curr Biol. 2009 Jan 27;19(2):95-107. doi: 10.1016/j.cub.2008.12.029. Epub 2009 Jan 15.

39.

High-affinity small molecule-phospholipid complex formation: binding of siramesine to phosphatidic acid.

Parry MJ, Alakoskela JM, Khandelia H, Kumar SA, Jäättelä M, Mahalka AK, Kinnunen PK.

J Am Chem Soc. 2008 Oct 1;130(39):12953-60. doi: 10.1021/ja800516w. Epub 2008 Sep 4.

PMID:
18767848
40.

Membrane insertion of the three main membranotropic sequences from SARS-CoV S2 glycoprotein.

Guillén J, Kinnunen PK, Villalaín J.

Biochim Biophys Acta. 2008 Dec;1778(12):2765-74. doi: 10.1016/j.bbamem.2008.07.021. Epub 2008 Aug 5.

41.

Interfacial behavior of cholesterol, ergosterol, and lanosterol in mixtures with DPPC and DMPC.

Sabatini K, Mattila JP, Kinnunen PK.

Biophys J. 2008 Sep;95(5):2340-55. doi: 10.1529/biophysj.108.132076. Epub 2008 May 30.

42.

Oxidized phospholipids as potential molecular targets for antimicrobial peptides.

Mattila JP, Sabatini K, Kinnunen PK.

Biochim Biophys Acta. 2008 Oct;1778(10):2041-50. doi: 10.1016/j.bbamem.2008.03.020. Epub 2008 Apr 8.

43.

Cholesterol, lanosterol, and ergosterol attenuate the membrane association of LL-37(W27F) and temporin L.

Sood R, Kinnunen PK.

Biochim Biophys Acta. 2008 Jun;1778(6):1460-6. doi: 10.1016/j.bbamem.2008.02.014. Epub 2008 Mar 5.

44.

Amyloid-type fiber formation in control of enzyme action: interfacial activation of phospholipase A2.

Code C, Domanov Y, Jutila A, Kinnunen PK.

Biophys J. 2008 Jul;95(1):215-24. doi: 10.1529/biophysj.108.128710. Epub 2008 Mar 13.

45.

Assessment of drug-lipid complex formation by a high-throughput Langmuir-balance and correlation to phospholipidosis.

Vitovic P, Alakoskela JM, Kinnunen PK.

J Med Chem. 2008 Mar 27;51(6):1842-8. doi: 10.1021/jm7013953. Epub 2008 Mar 5.

PMID:
18318464
46.

Interaction of cytochrome c with 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine: evidence for acyl chain reversal.

Mattila JP, Sabatini K, Kinnunen PK.

Langmuir. 2008 Apr 15;24(8):4157-60. doi: 10.1021/la703940s. Epub 2008 Mar 4.

PMID:
18315024
47.

Membranes: a meeting point for lipids, proteins and therapies.

Escribá PV, González-Ros JM, Goñi FM, Kinnunen PK, Vigh L, Sánchez-Magraner L, Fernández AM, Busquets X, Horváth I, Barceló-Coblijn G.

J Cell Mol Med. 2008 Jun;12(3):829-75. doi: 10.1111/j.1582-4934.2008.00281.x. Epub 2008 Feb 8. Review.

48.

Enantiospecific interactions between cholesterol and phospholipids.

Alakoskela JM, Sabatini K, Jiang X, Laitala V, Covey DF, Kinnunen PK.

Langmuir. 2008 Feb 5;24(3):830-6. doi: 10.1021/la702909q. Epub 2008 Jan 3.

PMID:
18171092
49.

Binding of LL-37 to model biomembranes: insight into target vs host cell recognition.

Sood R, Domanov Y, Pietiäinen M, Kontinen VP, Kinnunen PK.

Biochim Biophys Acta. 2008 Apr;1778(4):983-96. doi: 10.1016/j.bbamem.2007.11.016. Epub 2007 Dec 14.

50.

Islet amyloid polypeptide forms rigid lipid-protein amyloid fibrils on supported phospholipid bilayers.

Domanov YA, Kinnunen PK.

J Mol Biol. 2008 Feb 8;376(1):42-54. Epub 2007 Dec 4.

PMID:
18155730

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