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Items: 1 to 50 of 423

1.

ADAM15 in apoptosis resistance of synovial fibroblasts: converting Fas/CD95 death signals into the activation of pro-survival pathways by calmodulin recruitment.

Janczi T, Beate BB, Fehrl Y, DeGiacomo P, Kinne RW, Burkhardt H.

Arthritis Rheumatol. 2018 Jul 13. doi: 10.1002/art.40667. [Epub ahead of print]

PMID:
30003689
2.

In Vitro Analysis of Cartilage Regeneration Using a Collagen Type I Hydrogel (CaReS) in the Bovine Cartilage Punch Model.

Horbert V, Xin L, Foehr P, Brinkmann O, Bungartz M, Burgkart RH, Graeve T, Kinne RW.

Cartilage. 2018 Feb 1:1947603518756985. doi: 10.1177/1947603518756985. [Epub ahead of print]

PMID:
29463136
3.

FSP1-specific SMAD2 knockout in renal tubular, endothelial, and interstitial cells reduces fibrosis and epithelial-to-mesenchymal transition in murine STZ-induced diabetic nephropathy.

Loeffler I, Liebisch M, Allert S, Kunisch E, Kinne RW, Wolf G.

Cell Tissue Res. 2018 Apr;372(1):115-133. doi: 10.1007/s00441-017-2754-1. Epub 2017 Dec 6.

PMID:
29209813
4.

Erratum: Author's name correction.

Mika J, Brinkmann O, Clanton TO, Szalay G, Kinne RW.

J Orthop Case Rep. 2017 Jul-Aug;7(4):80. doi: 10.13107/jocr.2250-0685.864.

5.

Short-time pre-washing of brushite-forming calcium phosphate cement improves its in vitro cytocompatibility.

Kunisch E, Maenz S, Knoblich M, Ploeger F, Jandt KD, Bossert J, Kinne RW, Alsalameh S.

Tissue Cell. 2017 Dec;49(6):697-710. doi: 10.1016/j.tice.2017.10.002. Epub 2017 Oct 14.

PMID:
29102397
6.

The GDF5 mutant BB-1 enhances the bone formation induced by an injectable, poly(l-lactide-co-glycolide) acid (PLGA) fiber-reinforced, brushite-forming cement in a sheep defect model of lumbar osteopenia.

Gunnella F, Kunisch E, Maenz S, Horbert V, Xin L, Mika J, Borowski J, Bischoff S, Schubert H, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Plöger F, Kinne RW, Brinkmann O, Bungartz M.

Spine J. 2018 Feb;18(2):357-369. doi: 10.1016/j.spinee.2017.10.002. Epub 2017 Oct 12.

PMID:
29031993
7.

Comparison of Near-Infrared Spectroscopy with Needle Indentation and Histology for the Determination of Cartilage Thickness in the Large Animal Model Sheep.

Horbert V, Lange M, Reuter T, Hoffmann M, Bischoff S, Borowski J, Schubert H, Driesch D, Mika J, Hurschler C, Kinne RW.

Cartilage. 2017 Oct 1:1947603517731851. doi: 10.1177/1947603517731851. [Epub ahead of print]

PMID:
28980486
8.

Surgical Preparation for Articular Cartilage Regeneration in the Osteoarthritic Knee Joint.

Mika J, Clanton TO, Ambrose CG, Kinne RW.

Cartilage. 2017 Oct;8(4):365-368. doi: 10.1177/1947603516670710. Epub 2016 Sep 28.

9.

GDF5 significantly augments the bone formation induced by an injectable, PLGA fiber-reinforced, brushite-forming cement in a sheep defect model of lumbar osteopenia.

Bungartz M, Kunisch E, Maenz S, Horbert V, Xin L, Gunnella F, Mika J, Borowski J, Bischoff S, Schubert H, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Plöger F, Kinne RW, Brinkmann O.

Spine J. 2017 Nov;17(11):1685-1698. doi: 10.1016/j.spinee.2017.06.007. Epub 2017 Jun 19.

PMID:
28642196
10.

Low-dose BMP-2 is sufficient to enhance the bone formation induced by an injectable, PLGA fiber-reinforced, brushite-forming cement in a sheep defect model of lumbar osteopenia.

Gunnella F, Kunisch E, Bungartz M, Maenz S, Horbert V, Xin L, Mika J, Borowski J, Bischoff S, Schubert H, Hortschansky P, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Plöger F, Kinne RW, Brinkmann O.

Spine J. 2017 Nov;17(11):1699-1711. doi: 10.1016/j.spinee.2017.06.005. Epub 2017 Jun 12.

PMID:
28619686
11.

Detailed spatial characterization of superficial hip muscle activation during walking: A multi-electrode surface EMG investigation of the gluteal region in healthy older adults.

Anders C, Patenge S, Sander K, Layher F, Biedermann U, Kinne RW.

PLoS One. 2017 Jun 5;12(6):e0178957. doi: 10.1371/journal.pone.0178957. eCollection 2017.

12.

Enhanced bone formation in sheep vertebral bodies after minimally invasive treatment with a novel, PLGA fiber-reinforced brushite cement.

Maenz S, Brinkmann O, Kunisch E, Horbert V, Gunnella F, Bischoff S, Schubert H, Sachse A, Xin L, Günster J, Illerhaus B, Jandt KD, Bossert J, Kinne RW, Bungartz M.

Spine J. 2017 May;17(5):709-719. doi: 10.1016/j.spinee.2016.11.006. Epub 2016 Nov 15.

PMID:
27871820
13.

Decreased extrusion of calcium phosphate cement versus high viscosity PMMA cement into spongious bone marrow-an ex vivo and in vivo study in sheep vertebrae.

Xin L, Bungartz M, Maenz S, Horbert V, Hennig M, Illerhaus B, Günster J, Bossert J, Bischoff S, Borowski J, Schubert H, Jandt KD, Kunisch E, Kinne RW, Brinkmann O.

Spine J. 2016 Dec;16(12):1468-1477. doi: 10.1016/j.spinee.2016.07.529. Epub 2016 Aug 2.

PMID:
27496285
14.

First-time systematic postoperative clinical assessment of a minimally invasive approach for lumbar ventrolateral vertebroplasty in the large animal model sheep.

Bungartz M, Maenz S, Kunisch E, Horbert V, Xin L, Gunnella F, Mika J, Borowski J, Bischoff S, Schubert H, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Kinne RW, Brinkmann O.

Spine J. 2016 Oct;16(10):1263-1275. doi: 10.1016/j.spinee.2016.06.015. Epub 2016 Jun 23.

PMID:
27345746
15.

Isolated Acute Exertional Compartment Syndrome (AECS) of the Extensor Carpi Ulnaris.

Mika J, Brinkmann O, Clanton TO, Szalay G, Kinne RW.

J Orthop Case Rep. 2016 Jan-Mar;6(1):5-7. doi: 10.13107/jocr.2250-0685.362. Erratum in: J Orthop Case Rep. 2017 Jul-Aug;7(4):80.

16.

Effects of oxygen plasma treatment on interfacial shear strength and post-peak residual strength of a PLGA fiber-reinforced brushite cement.

Maenz S, Hennig M, Mühlstädt M, Kunisch E, Bungartz M, Brinkmann O, Bossert J, Kinne RW, Jandt KD.

J Mech Behav Biomed Mater. 2016 Apr;57:347-58. doi: 10.1016/j.jmbbm.2016.01.030. Epub 2016 Feb 5.

PMID:
26875148
17.

Are surface antigens suited to verify the redifferentiation potential and culture purity of human chondrocytes in cell-based implants.

Krüger M, Krüger JP, Kinne RW, Kaps C, Endres M.

Tissue Cell. 2015 Oct;47(5):489-97. doi: 10.1016/j.tice.2015.07.004. Epub 2015 Jul 17.

PMID:
26254705
18.

Identification of phlorizin binding domains in sodium-glucose cotransporter family: SGLT1 as a unique model system.

Raja M, Kinne RK.

Biochimie. 2015 Aug;115:187-93. doi: 10.1016/j.biochi.2015.06.003. Epub 2015 Jun 15.

PMID:
26086341
19.

Pathogenic mutations causing glucose transport defects in GLUT1 transporter: The role of intermolecular forces in protein structure-function.

Raja M, Kinne RK.

Biophys Chem. 2015 May-Jun;200-201:9-17. doi: 10.1016/j.bpc.2015.03.005. Epub 2015 Mar 25. Review.

PMID:
25863194
20.

Functional role of the KCa3.1 potassium channel in synovial fibroblasts from rheumatoid arthritis patients.

Friebel K, Schönherr R, Kinne RW, Kunisch E.

J Cell Physiol. 2015 Jul;230(7):1677-88. doi: 10.1002/jcp.24924.

PMID:
25545021
21.
22.

Enhanced mechanical properties of a novel, injectable, fiber-reinforced brushite cement.

Maenz S, Kunisch E, Mühlstädt M, Böhm A, Kopsch V, Bossert J, Kinne RW, Jandt KD.

J Mech Behav Biomed Mater. 2014 Nov;39:328-38. doi: 10.1016/j.jmbbm.2014.07.028. Epub 2014 Aug 7.

PMID:
25171749
23.

Novel application of multi-stimuli network inference to synovial fibroblasts of rheumatoid arthritis patients.

Kupfer P, Huber R, Weber M, Vlaic S, Häupl T, Koczan D, Guthke R, Kinne RW.

BMC Med Genomics. 2014 Jul 3;7:40. doi: 10.1186/1755-8794-7-40.

24.

Forces and dynamics of glucose and inhibitor binding to sodium glucose co-transporter SGLT1 studied by single molecule force spectroscopy.

Neundlinger I, Puntheeranurak T, Wildling L, Rankl C, Wang LX, Gruber HJ, Kinne RK, Hinterdorfer P.

J Biol Chem. 2014 Aug 1;289(31):21673-83. doi: 10.1074/jbc.M113.529875. Epub 2014 Jun 24.

25.

Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.

Woetzel D, Huber R, Kupfer P, Pohlers D, Pfaff M, Driesch D, Häupl T, Koczan D, Stiehl P, Guthke R, Kinne RW.

Arthritis Res Ther. 2014 Apr 1;16(2):R84. doi: 10.1186/ar4526.

26.

Laser-structured bacterial nanocellulose hydrogels support ingrowth and differentiation of chondrocytes and show potential as cartilage implants.

Ahrem H, Pretzel D, Endres M, Conrad D, Courseau J, Müller H, Jaeger R, Kaps C, Klemm DO, Kinne RW.

Acta Biomater. 2014 Mar;10(3):1341-53. doi: 10.1016/j.actbio.2013.12.004. Epub 2013 Dec 12.

PMID:
24334147
27.

ADAM15 adds to apoptosis resistance of synovial fibroblasts by modulating focal adhesion kinase signaling.

Böhm BB, Freund I, Krause K, Kinne RW, Burkhardt H.

Arthritis Rheum. 2013 Nov;65(11):2826-34. doi: 10.1002/art.38109.

28.
29.

[The bovine cartilage punch model: a tool for the in vitro analysis of biomaterials and cartilage regeneration].

Dunzel A, Rüdiger T, Pretzel D, Kopsch V, Endres M, Kaps C, Föhr P, Burgkart RH, Linß S, Kinne RW.

Orthopade. 2013 Apr;42(4):254-61. doi: 10.1007/s00132-012-1954-3. German.

PMID:
23508463
30.

(Auto)immunity to cartilage matrix proteins - a time bomb?

Kinne RW.

Arthritis Res Ther. 2013 Jan 21;15(1):101. doi: 10.1186/ar4123.

31.

SLC5 and SLC2 transporters in epithelia-cellular role and molecular mechanisms.

Raja M, Puntheeranurak T, Hinterdorfer P, Kinne R.

Curr Top Membr. 2012;70:29-76. doi: 10.1016/B978-0-12-394316-3.00002-8. Review.

PMID:
23177983
32.

An ovine in vitro model for chondrocyte-based scaffold-assisted cartilage grafts.

Endres M, Neumann K, Zhou B, Freymann U, Pretzel D, Stoffel M, Kinne RW, Kaps C.

J Orthop Surg Res. 2012 Nov 9;7:37. doi: 10.1186/1749-799X-7-37.

33.

Cytocompatibility of polymer-based periodontal bone substitutes in gingival fibroblast and MC3T3 osteoblast cell cultures.

Ruediger T, Berg A, Guellmar A, Rode C, Schnabelrauch M, Urbanek A, Wagner K, Wyrwa R, Kinne RW, Sigusch BW.

Dent Mater. 2012 Oct;28(10):e239-49. doi: 10.1016/j.dental.2012.05.008. Epub 2012 Jun 23.

PMID:
22727357
34.

Batch correction of microarray data substantially improves the identification of genes differentially expressed in rheumatoid arthritis and osteoarthritis.

Kupfer P, Guthke R, Pohlers D, Huber R, Koczan D, Kinne RW.

BMC Med Genomics. 2012 Jun 8;5:23. doi: 10.1186/1755-8794-5-23.

35.

[Gait analysis after minimally invasive total hip arthroplasty].

Sander K, Layher F, Anders C, Roth A, Babisch J, Scholle HC, Kinne RW.

Orthopade. 2012 May;41(5):365-76. doi: 10.1007/s00132-011-1891-6. German.

PMID:
22552542
36.
37.

Hepatic Fibrosis in a Long-term Murine Model of Sepsis.

Gonnert FA, Kunisch E, Gajda M, Lambeck S, Weber M, Claus RA, Bauer M, Kinne RW.

Shock. 2012 Apr;37(4):399-407. doi: 10.1097/SHK.0b013e31824a670b.

PMID:
22266973
38.

IL-33 regulates TNF-α dependent effects in synovial fibroblasts.

Kunisch E, Chakilam S, Gandesiri M, Kinne RW.

Int J Mol Med. 2012 Apr;29(4):530-40. doi: 10.3892/ijmm.2012.883. Epub 2012 Jan 10.

39.

Single-molecule recognition force spectroscopy of transmembrane transporters on living cells.

Puntheeranurak T, Neundlinger I, Kinne RK, Hinterdorfer P.

Nat Protoc. 2011 Sep 1;6(9):1443-52. doi: 10.1038/nprot.2011.370.

PMID:
21886107
40.

Relative percentage and zonal distribution of mesenchymal progenitor cells in human osteoarthritic and normal cartilage.

Pretzel D, Linss S, Rochler S, Endres M, Kaps C, Alsalameh S, Kinne RW.

Arthritis Res Ther. 2011 Apr 15;13(2):R64. doi: 10.1186/ar3320.

41.

SGLT inhibitors as new therapeutic tools in the treatment of diabetes.

Kinne RK, Castaneda F.

Handb Exp Pharmacol. 2011;(203):105-26. doi: 10.1007/978-3-642-17214-4_5. Review.

PMID:
21484569
42.

A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblasts.

Geurts J, Vermeij EA, Pohlers D, Arntz OJ, Kinne RW, van den Berg WB, van de Loo FA.

Ann Rheum Dis. 2011 Jul;70(7):1311-9. doi: 10.1136/ard.2010.135665. Epub 2011 Apr 7.

PMID:
21474483
43.

Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients.

Bittner S, Bobak N, Feuchtenberger M, Herrmann AM, Göbel K, Kinne RW, Hansen AJ, Budde T, Kleinschnitz C, Frey O, Tony HP, Wiendl H, Meuth SG.

Arthritis Res Ther. 2011 Feb 11;13(1):R21. doi: 10.1186/ar3245.

44.

Clinical impact of radiolabeled anti-CD4 antibodies in the diagnosis of rheumatoid arthritis.

Kinne RW, Emmrich F, Freesmeyer M.

Q J Nucl Med Mol Imaging. 2010 Dec;54(6):629-38. Review.

PMID:
21221070
45.

Surgical preparation for articular cartilage regeneration without penetration of the subchondral bone plate: in vitro and in vivo studies in humans and sheep.

Mika J, Clanton TO, Pretzel D, Schneider G, Ambrose CG, Kinne RW.

Am J Sports Med. 2011 Mar;39(3):624-31. doi: 10.1177/0363546510388876. Epub 2011 Jan 6.

PMID:
21212304
46.

A biophysical glance at the outer surface of the membrane transporter SGLT1.

Tyagi NK, Puntheeranurak T, Raja M, Kumar A, Wimmer B, Neundlinger I, Gruber H, Hinterdorfer P, Kinne RK.

Biochim Biophys Acta. 2011 Jan;1808(1):1-18. doi: 10.1016/j.bbamem.2010.07.028. Epub 2010 Aug 6. Review.

47.

Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis.

Anderson R, Franch A, Castell M, Perez-Cano FJ, Bräuer R, Pohlers D, Gajda M, Siskos AP, Katsila T, Tamvakopoulos C, Rauchhaus U, Panzner S, Kinne RW.

Arthritis Res Ther. 2010;12(4):R147. doi: 10.1186/ar3089. Epub 2010 Jul 19.

48.

CD11c as a transcriptional biomarker to predict response to anti-TNF monotherapy with adalimumab in patients with rheumatoid arthritis.

Stuhlmüller B, Häupl T, Hernandez MM, Grützkau A, Kuban RJ, Tandon N, Voss JW, Salfeld J, Kinne RW, Burmester GR.

Clin Pharmacol Ther. 2010 Mar;87(3):311-21. doi: 10.1038/clpt.2009.244. Epub 2009 Dec 23.

PMID:
20032971
49.

Targeted delivery of liposomal dexamethasone phosphate to the spleen provides a persistent therapeutic effect in rat antigen-induced arthritis.

Rauchhaus U, Kinne RW, Pohlers D, Wiegand S, Wölfert A, Gajda M, Bräuer R, Panzner S.

Ann Rheum Dis. 2009 Dec;68(12):1933-4. doi: 10.1136/ard.2009.108985. No abstract available.

PMID:
19910302
50.

Adapted Boolean network models for extracellular matrix formation.

Wollbold J, Huber R, Pohlers D, Koczan D, Guthke R, Kinne RW, Gausmann U.

BMC Syst Biol. 2009 Jul 21;3:77. doi: 10.1186/1752-0509-3-77.

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