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Items: 27


Leukemia-derived exosomes and cytokines pave the way for entry into the brain.

Kinjyo I, Bragin D, Grattan R, Winter SS, Wilson BS.

J Leukoc Biol. 2019 Apr;105(4):741-753. doi: 10.1002/JLB.3A0218-054R. Epub 2019 Jan 31.


Characterization of the anti-CD22 targeted therapy, moxetumomab pasudotox, for B-cell precursor acute lymphoblastic leukemia.

Kinjyo I, Matlawska-Wasowska K, Chen X, Monks NR, Burke P, Winter SS, Wilson BS.

Pediatr Blood Cancer. 2017 Nov;64(11). doi: 10.1002/pbc.26604. Epub 2017 Apr 27.


Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphoblastic leukemia.

Erasmus MF, Matlawska-Wasowska K, Kinjyo I, Mahajan A, Winter SS, Xu L, Horowitz M, Lidke DS, Wilson BS.

Sci Signal. 2016 Nov 29;9(456):ra116.


Shedding light on cell cycle control by T and B lymphocytes.

Kinjyo I, Weninger W, Hodgkin PD.

Cell Cycle. 2015 Aug 3;14(15):2381-2. doi: 10.1080/15384101.2015.1063291. Epub 2015 Jul 1. No abstract available.


Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation.

Kinjyo I, Qin J, Tan SY, Wellard CJ, Mrass P, Ritchie W, Doi A, Cavanagh LL, Tomura M, Sakaue-Sawano A, Kanagawa O, Miyawaki A, Hodgkin PD, Weninger W.

Nat Commun. 2015 Feb 24;6:6301. doi: 10.1038/ncomms7301.


Real-time cell cycle imaging during melanoma growth, invasion, and drug response.

Haass NK, Beaumont KA, Hill DS, Anfosso A, Mrass P, Munoz MA, Kinjyo I, Weninger W.

Pigment Cell Melanoma Res. 2014 Sep;27(5):764-76. doi: 10.1111/pcmr.12274. Epub 2014 Jun 27.


Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division.

Chang JT, Ciocca ML, Kinjyo I, Palanivel VR, McClurkin CE, Dejong CS, Mooney EC, Kim JS, Steinel NC, Oliaro J, Yin CC, Florea BI, Overkleeft HS, Berg LJ, Russell SM, Koretzky GA, Jordan MS, Reiner SL.

Immunity. 2011 Apr 22;34(4):492-504. doi: 10.1016/j.immuni.2011.03.017. Epub 2011 Apr 14.


Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.

Kinjyo I, Gordon SM, Intlekofer AM, Dowdell K, Mooney EC, Caricchio R, Grupp SA, Teachey DT, Rao VK, Lindsten T, Reiner SL.

J Immunol. 2010 Dec 15;185(12):7151-5. doi: 10.4049/jimmunol.1003193. Epub 2010 Nov 12.


Silencing of SOCS1 in macrophages suppresses tumor development by enhancing antitumor inflammation.

Hashimoto M, Ayada T, Kinjyo I, Hiwatashi K, Yoshida H, Okada Y, Kobayashi T, Yoshimura A.

Cancer Sci. 2009 Apr;100(4):730-6.


Cyclic adenosine monophosphate suppresses the transcription of proinflammatory cytokines via the phosphorylated c-Fos protein.

Koga K, Takaesu G, Yoshida R, Nakaya M, Kobayashi T, Kinjyo I, Yoshimura A.

Immunity. 2009 Mar 20;30(3):372-83. doi: 10.1016/j.immuni.2008.12.021. Epub 2009 Mar 12. Erratum in: Immunity. 2009 Jul 17;31(1):170.


CD44 mediates successful interstitial navigation by killer T cells and enables efficient antitumor immunity.

Mrass P, Kinjyo I, Ng LG, Reiner SL, Puré E, Weninger W.

Immunity. 2008 Dec 19;29(6):971-85. doi: 10.1016/j.immuni.2008.10.015.


Two-photon imaging of effector T-cell behavior: lessons from a tumor model.

Ng LG, Mrass P, Kinjyo I, Reiner SL, Weninger W.

Immunol Rev. 2008 Feb;221:147-62. doi: 10.1111/j.1600-065X.2008.00596.x. Review.


Positive and negative roles of IL-6, STAT3, and SOCS3 in inflammatory arthritis.

Kinjyo I, Ohishi M, Shouda T, Kobayashi T, Yoshimura A.

Adv Exp Med Biol. 2007;602:113-24. No abstract available.


Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

Chang JT, Palanivel VR, Kinjyo I, Schambach F, Intlekofer AM, Banerjee A, Longworth SA, Vinup KE, Mrass P, Oliaro J, Killeen N, Orange JS, Russell SM, Weninger W, Reiner SL.

Science. 2007 Mar 23;315(5819):1687-91. Epub 2007 Mar 1.


Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1.

Kinjyo I, Inoue H, Hamano S, Fukuyama S, Yoshimura T, Koga K, Takaki H, Himeno K, Takaesu G, Kobayashi T, Yoshimura A.

J Exp Med. 2006 Apr 17;203(4):1021-31. Epub 2006 Apr 10.


Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production.

Ogata H, Chinen T, Yoshida T, Kinjyo I, Takaesu G, Shiraishi H, Iida M, Kobayashi T, Yoshimura A.

Oncogene. 2006 Apr 20;25(17):2520-30.


The neuropeptide neuromedin U activates eosinophils and is involved in allergen-induced eosinophilia.

Moriyama M, Fukuyama S, Inoue H, Matsumoto T, Sato T, Tanaka K, Kinjyo I, Kano T, Yoshimura A, Kojima M.

Am J Physiol Lung Cell Mol Physiol. 2006 May;290(5):L971-7. Epub 2005 Dec 22.


Analysis of SOCS-3 promoter responses to interferon gamma.

Gatto L, Berlato C, Poli V, Tininini S, Kinjyo I, Yoshimura A, Cassatella MA, Bazzoni F.

J Biol Chem. 2004 Apr 2;279(14):13746-54. Epub 2004 Jan 23.


SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling.

Kimura A, Kinjyo I, Matsumura Y, Mori H, Mashima R, Harada M, Chien KR, Yasukawa H, Yoshimura A.

J Biol Chem. 2004 Feb 20;279(8):6905-10. Epub 2003 Dec 29.


Negative regulation of cytokine signaling by CIS/SOCS family proteins and their roles in inflammatory diseases.

Hanada T, Kinjyo I, Inagaki-Ohara K, Yoshimura A.

Rev Physiol Biochem Pharmacol. 2003;149:72-86. Epub 2003 Mar 29. Review.


SOCS1/JAB is a negative regulator of LPS-induced macrophage activation.

Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M, Yoshimura A.

Immunity. 2002 Nov;17(5):583-91.


Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation.

Berlato C, Cassatella MA, Kinjyo I, Gatto L, Yoshimura A, Bazzoni F.

J Immunol. 2002 Jun 15;168(12):6404-11.


A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.

Hanada T, Yoshida T, Kinjyo I, Minoguchi S, Yasukawa H, Kato S, Mimata H, Nomura Y, Seki Y, Kubo M, Yoshimura A.

J Biol Chem. 2001 Nov 2;276(44):40746-54. Epub 2001 Aug 24.


The janus kinase inhibitor, Jab/SOCS-1, is an interferon-gamma inducible gene and determines the sensitivity to interferons.

Sakamoto H, Kinjyo I, Yoshimura A.

Leuk Lymphoma. 2000 Jun;38(1-2):49-58. Review.


Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain.

Sasaki A, Yasukawa H, Suzuki A, Kamizono S, Syoda T, Kinjyo I, Sasaki M, Johnston JA, Yoshimura A.

Genes Cells. 1999 Jun;4(6):339-51.


Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway.

Yoshimura A, Ichihara M, Kinjyo I, Moriyama M, Copeland NG, Gilbert DJ, Jenkins NA, Hara T, Miyajima A.

EMBO J. 1996 Mar 1;15(5):1055-63.

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