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Changes in plasma lipids predict pravastatin efficacy in secondary prevention.

Jayawardana KS, Mundra PA, Giles C, Barlow CK, Nestel PJ, Barnes EH, Kirby A, Thompson P, Sullivan DR, Alshehry ZH, Mellett NA, Huynh K, McConville MJ, Zoungas S, Hillis GS, Chalmers J, Woodward M, Marschner IC, Wong G, Kingwell BA, Simes J, Tonkin AM, Meikle PJ; LIPID Study Investigators.

JCI Insight. 2019 Jul 11;4(13). pii: 128438. doi: 10.1172/jci.insight.128438. eCollection 2019 Jul 11.


Building an Academic-Industry Partnership to Tackle Australia's Biggest Health Burden.

Climie RE, Kingwell BA, Figtree GA.

Heart Lung Circ. 2019 Aug;28(8):1144-1147. doi: 10.1016/j.hlc.2019.05.174.


Impact of Pre-Procedural Blood Pressure on Long-Term Outcomes Following Percutaneous Coronary Intervention.

Warren J, Nanayakkara S, Andrianopoulos N, Brennan A, Dinh D, Yudi M, Clark D, Ajani AE, Reid CM, Selkrig L, Shaw J, Hiew C, Freeman M, Kaye D, Kingwell BA, Dart AM, Duffy SJ; Melbourne Interventional Group Investigators.

J Am Coll Cardiol. 2019 Jun 11;73(22):2846-2855. doi: 10.1016/j.jacc.2019.03.493.


HDL Phospholipids, but Not Cholesterol Distinguish Acute Coronary Syndrome From Stable Coronary Artery Disease.

Meikle PJ, Formosa MF, Mellett NA, Jayawardana KS, Giles C, Bertovic DA, Jennings GL, Childs W, Reddy M, Carey AL, Baradi A, Nanayakkara S, Wilson AM, Duffy SJ, Kingwell BA.

J Am Heart Assoc. 2019 Jun 4;8(11):e011792. doi: 10.1161/JAHA.118.011792.


Distinct effects of acute exercise and breaks in sitting on working memory and executive function in older adults: a three-arm, randomised cross-over trial to evaluate the effects of exercise with and without breaks in sitting on cognition.

Wheeler MJ, Green DJ, Ellis KA, Cerin E, Heinonen I, Naylor LH, Larsen R, Wennberg P, Boraxbekk CJ, Lewis J, Eikelis N, Lautenschlager NT, Kingwell BA, Lambert G, Owen N, Dunstan DW.

Br J Sports Med. 2019 Apr 29. pii: bjsports-2018-100168. doi: 10.1136/bjsports-2018-100168. [Epub ahead of print]


Rethinking good cholesterol: a clinicians' guide to understanding HDL.

Xiang AS, Kingwell BA.

Lancet Diabetes Endocrinol. 2019 Jul;7(7):575-582. doi: 10.1016/S2213-8587(19)30003-8. Epub 2019 Mar 22. Review.


Acute effects of active breaks during prolonged sitting on subcutaneous adipose tissue gene expression: an ancillary analysis of a randomised controlled trial.

Grace MS, Formosa MF, Bozaoglu K, Bergouignan A, Brozynska M, Carey AL, Veiga CB, Sethi P, Dillon F, Bertovic DA, Inouye M, Owen N, Dunstan DW, Kingwell BA.

Sci Rep. 2019 Mar 7;9(1):3847. doi: 10.1038/s41598-019-40490-0.


Effect of Morning Exercise With or Without Breaks in Prolonged Sitting on Blood Pressure in Older Overweight/Obese Adults.

Wheeler MJ, Dunstan DW, Ellis KA, Cerin E, Phillips S, Lambert G, Naylor LH, Dempsey PC, Kingwell BA, Green DJ.

Hypertension. 2019 Apr;73(4):859-867. doi: 10.1161/HYPERTENSIONAHA.118.12373.


Sex-Specific Lifestyle and Biomedical Risk Factors for Chronic Disease among Early-Middle, Middle and Older Aged Australian Adults.

Dash SR, Hoare E, Varsamis P, Jennings GLR, Kingwell BA.

Int J Environ Res Public Health. 2019 Jan 15;16(2). pii: E224. doi: 10.3390/ijerph16020224.


The E3 ligase MARCH5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes.

Bond ST, Moody SC, Liu Y, Civelek M, Villanueva CJ, Gregorevic P, Kingwell BA, Hevener AL, Lusis AJ, Henstridge DC, Calkin AC, Drew BG.

Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E293-E304. doi: 10.1152/ajpendo.00394.2018. Epub 2018 Dec 4.


Sitting Less and Moving More: Implications for Hypertension.

Dempsey PC, Larsen RN, Dunstan DW, Owen N, Kingwell BA.

Hypertension. 2018 Nov;72(5):1037-1046. doi: 10.1161/HYPERTENSIONAHA.118.11190. Review. No abstract available.


Between-meal sucrose-sweetened beverage consumption impairs glycaemia and lipid metabolism during prolonged sitting: A randomized controlled trial.

Varsamis P, Formosa MF, Larsen RN, Reddy-Luthmoodoo M, Jennings GL, Cohen ND, Grace M, Hawley JA, Devlin BL, Owen N, Dunstan DW, Dempsey PC, Kingwell BA.

Clin Nutr. 2019 Aug;38(4):1536-1543. doi: 10.1016/j.clnu.2018.08.021. Epub 2018 Sep 1.


Acute metabolic and cardiovascular effects of mirabegron in healthy individuals.

Loh RKC, Formosa MF, La Gerche A, Reutens AT, Kingwell BA, Carey AL.

Diabetes Obes Metab. 2019 Feb;21(2):276-284. doi: 10.1111/dom.13516. Epub 2018 Sep 24.


Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention.

Mundra PA, Barlow CK, Nestel PJ, Barnes EH, Kirby A, Thompson P, Sullivan DR, Alshehry ZH, Mellett NA, Huynh K, Jayawardana KS, Giles C, McConville MJ, Zoungas S, Hillis GS, Chalmers J, Woodward M, Wong G, Kingwell BA, Simes J, Tonkin AM, Meikle PJ; LIPID Study Investigators.

JCI Insight. 2018 Sep 6;3(17). pii: 121326. doi: 10.1172/jci.insight.121326. eCollection 2018 Sep 6.


Regular brief interruptions to sitting after a high-energy evening meal attenuate glycemic excursions in overweight/obese adults.

Climie RE, Grace MS, Larsen RL, Dempsey PC, Oberoi J, Cohen ND, Owen N, Kingwell BA, Dunstan DW.

Nutr Metab Cardiovasc Dis. 2018 Sep;28(9):909-916. doi: 10.1016/j.numecd.2018.05.009. Epub 2018 May 26.


Potential implications of the new American hypertension guidelines in Australia.

Jennings GL, Kingwell BA, Hoare E.

Med J Aust. 2018 Aug 6;209(3):108-109. No abstract available.


Brown adipose tissue and lipid metabolism: New strategies for identification of activators and biomarkers with clinical potential.

Xiang AS, Meikle PJ, Carey AL, Kingwell BA.

Pharmacol Ther. 2018 Dec;192:141-149. doi: 10.1016/j.pharmthera.2018.07.002. Epub 2018 Jul 24. Review.


Exploring Motivation and Barriers to Physical Activity among Active and Inactive Australian Adults.

Hoare E, Stavreski B, Jennings GL, Kingwell BA.

Sports (Basel). 2017 Jun 28;5(3). pii: E47. doi: 10.3390/sports5030047.


Blood Pressure Down Under, but Down Under What? US and Australian Hypertension Guideline Conversation.

Hoare E, Kingwell BA, Jennings GLR.

Hypertension. 2018 Jun;71(6):972-975. doi: 10.1161/HYPERTENSIONAHA.118.11026. Epub 2018 Apr 23. No abstract available.


Standing up to the cardiometabolic consequences of hematological cancers.

Howden EJ, La Gerche A, Arthur JF, McMullen JR, Jennings GL, Dunstan DW, Owen N, Avery S, Kingwell BA.

Blood Rev. 2018 Sep;32(5):349-360. doi: 10.1016/j.blre.2018.02.005. Epub 2018 Feb 21. Review.


Left Ventricular Dysfunction and Exercise Capacity Trajectory: Implications for Subclinical Heart Failure Staging Criteria.

Sacre JW, Wong C, Chan YK, Carrington MJ, Stewart S, Kingwell BA.

JACC Cardiovasc Imaging. 2019 May;12(5):798-806. doi: 10.1016/j.jcmg.2017.10.023. Epub 2018 Feb 14.


Prolonged uninterrupted sitting elevates postprandial hyperglycaemia proportional to degree of insulin resistance.

Dempsey PC, Larsen RN, Winkler EAH, Owen N, Kingwell BA, Dunstan DW.

Diabetes Obes Metab. 2018 Jun;20(6):1526-1530. doi: 10.1111/dom.13254. Epub 2018 Mar 6.


Sex-Specific Associations in Nutrition and Activity-Related Risk Factors for Chronic Disease: Australian Evidence from Childhood to Emerging Adulthood.

Hoare E, Dash SR, Jennings GL, Kingwell BA.

Int J Environ Res Public Health. 2018 Jan 26;15(2). pii: E214. doi: 10.3390/ijerph15020214.


Weight Loss and Exercise Alter the High-Density Lipoprotein Lipidome and Improve High-Density Lipoprotein Functionality in Metabolic Syndrome.

Khan AA, Mundra PA, Straznicky NE, Nestel PJ, Wong G, Tan R, Huynh K, Ng TW, Mellett NA, Weir JM, Barlow CK, Alshehry ZH, Lambert GW, Kingwell BA, Meikle PJ.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):438-447. doi: 10.1161/ATVBAHA.117.310212. Epub 2017 Dec 28.


High-density lipoprotein and cardiac glucose metabolism: Implications for management of acute coronary syndromes.

Richart AL, Heywood SE, Siebel AL, Kingwell BA.

Eur J Prev Cardiol. 2018 Feb;25(3):273-275. doi: 10.1177/2047487317748217. Epub 2017 Dec 14. No abstract available.


Correction to: Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans.

Loh RKC, Formosa MF, Eikelis N, Bertovic DA, Anderson MJ, Barwood SA, Nanayakkara S, Cohen ND, La Gerche A, Reutens AT, Yap KS, Barber TW, Lambert GW, Cherk MH, Duffy SJ, Kingwell BA, Carey AL.

Diabetologia. 2018 Feb;61(2):504-505. doi: 10.1007/s00125-017-4514-x.


Fasting Plasma Glucose, Self-Appraised Diet Quality and Depressive Symptoms: A US-Representative Cross-Sectional Study.

Hoare E, Dash SR, Varsamis P, Jennings GL, Kingwell BA.

Nutrients. 2017 Dec 7;9(12). pii: E1330. doi: 10.3390/nu9121330.


Cardiometabolic Impact of Changing Sitting, Standing, and Stepping in the Workplace.

Winkler EAH, Chastin S, Eakin EG, Owen N, Lamontagne AD, Moodie M, Dempsey PC, Kingwell BA, Dunstan DW, Healy GN.

Med Sci Sports Exerc. 2018 Mar;50(3):516-524. doi: 10.1249/MSS.0000000000001453.


Australian adults' behaviours, knowledge and perceptions of risk factors for heart disease: A cross-sectional study.

Hoare E, Stavreski B, Kingwell BA, Jennings GL.

Prev Med Rep. 2017 Oct 17;8:204-209. doi: 10.1016/j.pmedr.2017.10.007. eCollection 2017 Dec.


Prolonged uninterrupted sitting increases fatigue in type 2 diabetes.

Dempsey PC, Dunstan DW, Larsen RN, Lambert GW, Kingwell BA, Owen N.

Diabetes Res Clin Pract. 2018 Jan;135:128-133. doi: 10.1016/j.diabres.2017.11.001. Epub 2017 Nov 10.


Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans.

Loh RKC, Formosa MF, Eikelis N, Bertovic DA, Anderson MJ, Barwood SA, Nanayakkara S, Cohen ND, La Gerche A, Reutens AT, Yap KS, Barber TW, Lambert GW, Cherk MH, Duffy SJ, Kingwell BA, Carey AL.

Diabetologia. 2018 Jan;61(1):220-230. doi: 10.1007/s00125-017-4479-9. Epub 2017 Oct 18. Erratum in: Diabetologia. 2017 Dec 8;:.


High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice.

Heywood SE, Richart AL, Henstridge DC, Alt K, Kiriazis H, Zammit C, Carey AL, Kammoun HL, Delbridge LM, Reddy M, Chen YC, Du XJ, Hagemeyer CE, Febbraio MA, Siebel AL, Kingwell BA.

Sci Transl Med. 2017 Oct 11;9(411). pii: eaam6084. doi: 10.1126/scitranslmed.aam6084.


Sugar- and Intense-Sweetened Drinks in Australia: A Systematic Review on Cardiometabolic Risk.

Hoare E, Varsamis P, Owen N, Dunstan DW, Jennings GL, Kingwell BA.

Nutrients. 2017 Sep 28;9(10). pii: E1075. doi: 10.3390/nu9101075.


Mild cognitive impairment is associated with subclinical diastolic dysfunction in patients with chronic heart disease.

Sacre JW, Ball J, Wong C, Chan YK, Stewart S, Kingwell BA, Carrington MJ.

Eur Heart J Cardiovasc Imaging. 2018 Mar 1;19(3):285-292. doi: 10.1093/ehjci/jex169.


Better Indigenous Risk stratification for Cardiac Health study (BIRCH) protocol: rationale and design of a cross-sectional and prospective cohort study to identify novel cardiovascular risk indicators in Aboriginal Australian and Torres Strait Islander adults.

Rémond MGW, Stewart S, Carrington MJ, Marwick TH, Kingwell BA, Meikle P, O'Brien D, Marshall NS, Maguire GP.

BMC Cardiovasc Disord. 2017 Aug 23;17(1):228. doi: 10.1186/s12872-017-0662-7.


Baseline serum phosphatidylcholine plasmalogen concentrations are inversely associated with incident myocardial infarction in patients with mixed peripheral artery disease presentations.

Moxon JV, Jones RE, Wong G, Weir JM, Mellett NA, Kingwell BA, Meikle PJ, Golledge J.

Atherosclerosis. 2017 Aug;263:301-308. doi: 10.1016/j.atherosclerosis.2017.06.925. Epub 2017 Jun 29.


Human brown adipose tissue as a target for obesity management; beyond cold-induced thermogenesis.

Loh RKC, Kingwell BA, Carey AL.

Obes Rev. 2017 Nov;18(11):1227-1242. doi: 10.1111/obr.12584. Epub 2017 Jul 14. Review.


The sugar content of soft drinks in Australia, Europe and the United States.

Varsamis P, Larsen RN, Dunstan DW, Jennings GL, Owen N, Kingwell BA.

Med J Aust. 2017 Jun 5;206(10):454-455. No abstract available.


Does the type of activity "break" from prolonged sitting differentially impact on postprandial blood glucose reductions? An exploratory analysis.

Larsen RN, Dempsey PC, Dillon F, Grace M, Kingwell BA, Owen N, Dunstan DW.

Appl Physiol Nutr Metab. 2017 Aug;42(8):897-900. doi: 10.1139/apnm-2016-0642. Epub 2017 Mar 24.


Breaking Up Prolonged Sitting Alters the Postprandial Plasma Lipidomic Profile of Adults With Type 2 Diabetes.

Grace MS, Dempsey PC, Sethi P, Mundra PA, Mellett NA, Weir JM, Owen N, Dunstan DW, Meikle PJ, Kingwell BA.

J Clin Endocrinol Metab. 2017 Jun 1;102(6):1991-1999. doi: 10.1210/jc.2016-3926.


Interrupting prolonged sitting in type 2 diabetes: nocturnal persistence of improved glycaemic control.

Dempsey PC, Blankenship JM, Larsen RN, Sacre JW, Sethi P, Straznicky NE, Cohen ND, Cerin E, Lambert GW, Owen N, Kingwell BA, Dunstan DW.

Diabetologia. 2017 Mar;60(3):499-507. doi: 10.1007/s00125-016-4169-z. Epub 2016 Dec 9.


Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle.

Lee-Young RS, Hoffman NJ, Murphy KT, Henstridge DC, Samocha-Bonet D, Siebel AL, Iliades P, Zivanovic B, Hong YH, Colgan TD, Kraakman MJ, Bruce CR, Gregorevic P, McConell GK, Lynch GS, Drummond GR, Kingwell BA, Greenfield JR, Febbraio MA.

Mol Metab. 2016 Sep 9;5(11):1083-1091. doi: 10.1016/j.molmet.2016.09.002. eCollection 2016 Nov.


Interrupting prolonged sitting with brief bouts of light walking or simple resistance activities reduces resting blood pressure and plasma noradrenaline in type 2 diabetes.

Dempsey PC, Sacre JW, Larsen RN, Straznicky NE, Sethi P, Cohen ND, Cerin E, Lambert GW, Owen N, Kingwell BA, Dunstan DW.

J Hypertens. 2016 Dec;34(12):2376-2382.


Plasma Lipidomic Profiles Improve on Traditional Risk Factors for the Prediction of Cardiovascular Events in Type 2 Diabetes Mellitus.

Alshehry ZH, Mundra PA, Barlow CK, Mellett NA, Wong G, McConville MJ, Simes J, Tonkin AM, Sullivan DR, Barnes EH, Nestel PJ, Kingwell BA, Marre M, Neal B, Poulter NR, Rodgers A, Williams B, Zoungas S, Hillis GS, Chalmers J, Woodward M, Meikle PJ.

Circulation. 2016 Nov 22;134(21):1637-1650. Epub 2016 Oct 18.


Sitting Less and Moving More: Improved Glycaemic Control for Type 2 Diabetes Prevention and Management.

Dempsey PC, Owen N, Yates TE, Kingwell BA, Dunstan DW.

Curr Diab Rep. 2016 Nov;16(11):114. Review.


Frequent interruptions of sedentary time modulates contraction- and insulin-stimulated glucose uptake pathways in muscle: Ancillary analysis from randomized clinical trials.

Bergouignan A, Latouche C, Heywood S, Grace MS, Reddy-Luthmoodoo M, Natoli AK, Owen N, Dunstan DW, Kingwell BA.

Sci Rep. 2016 Aug 24;6:32044. doi: 10.1038/srep32044.


Benefits for Type 2 Diabetes of Interrupting Prolonged Sitting With Brief Bouts of Light Walking or Simple Resistance Activities.

Dempsey PC, Larsen RN, Sethi P, Sacre JW, Straznicky NE, Cohen ND, Cerin E, Lambert GW, Owen N, Kingwell BA, Dunstan DW.

Diabetes Care. 2016 Jun;39(6):964-72. doi: 10.2337/dc15-2336. Epub 2016 Apr 13.


Effects of the BET-inhibitor, RVX-208 on the HDL lipidome and glucose metabolism in individuals with prediabetes: A randomized controlled trial.

Siebel AL, Trinh SK, Formosa MF, Mundra PA, Natoli AK, Reddy-Luthmoodoo M, Huynh K, Khan AA, Carey AL, van Hall G, Cobelli C, Dalla-Man C, Otvos JD, Rye KA, Johansson J, Gordon A, Wong NC, Sviridov D, Barter P, Duffy SJ, Meikle PJ, Kingwell BA.

Metabolism. 2016 Jun;65(6):904-14. doi: 10.1016/j.metabol.2016.03.002. Epub 2016 Mar 8.


MicroRNA-194 Modulates Glucose Metabolism and Its Skeletal Muscle Expression Is Reduced in Diabetes.

Latouche C, Natoli A, Reddy-Luthmoodoo M, Heywood SE, Armitage JA, Kingwell BA.

PLoS One. 2016 May 10;11(5):e0155108. doi: 10.1371/journal.pone.0155108. eCollection 2016.


Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial.

de Courten B, de Courten MP, Soldatos G, Dougherty SL, Straznicky N, Schlaich M, Sourris KC, Chand V, Scheijen JL, Kingwell BA, Cooper ME, Schalkwijk CG, Walker KZ, Forbes JM.

Am J Clin Nutr. 2016 Jun;103(6):1426-33. doi: 10.3945/ajcn.115.125427. Epub 2016 Mar 30.


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